Publications

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relationships between cytauxzoon felis and african piroplasmids.a cat which had recovered from cytauxzoon felis infection following treatment with the anti-theilerial drug, parvaquone, showed an increase in piroplasm parasitemia after splenectomy and its blood was suitable for the preparation of antigen smears for the indirect fluorescent antibody test. high levels of antibodies were found in this cat after recovery, in two other cats sub-lethally infected with piroplasms and in sera of naturally infected bobcats. cats recovered from piroplasm infection died ...19873125663
a possible new piroplasm in lions from the republic of south africa.a small piroplasm was detected in blood smears from lions (panthera leo) in the kruger national park (knp; republic of south africa) during 1991/1992. the parasite was identified provisionally as babesia felis, but sera from these lions tested negative to b. felis antigen in the indirect immunofluorescent antibody test (ifat). blood from an infected lion was subsequently subinoculated into a domestic cat and two leopards in an attempt to identify the parasite. a lion also was infected with b. fe ...199910073351
screening of five drugs for efficacy against babesia felis in experimentally infected cats.the efficacy of 5 drugs was tested against experimental babesia felis infection in domestic cats. two of the drugs, rifampicin and a sulphadiazine-trimethoprim combination, appeared to have an anti-parasitic effect, but were inferior to primaquine. the other 3 drugs, buparvaquone, enrofloxacin and danofloxacin, had no significant anti-babesial effect.200010949519
occurrence of babesia felis and babesia leo in various wild felid species and domestic cats in southern africa, based on reverse line blot analysis.reverse line blot (rlb) is a hybridization assay that can be used to detect various blood parasites and differentiate between them. results, using the rlb, showed that babesia felis and babesia leo occurred as single or mixed infections in various felid species, but most frequently in domestic cats and lions, respectively. prevalence of infection in free-ranging cheetahs in namibia was low (7, 5%), whereas 50% of free-ranging lions in south africa and swaziland were infected. a large number (52, ...200717084029
surveillance for viral and parasitic pathogens in a vulnerable african lion (panthera leo) population in the northern tuli game reserve, botswana.african lion ( panthera leo ) numbers are decreasing rapidly and populations are becoming smaller and more fragmented. infectious diseases are one of numerous issues threatening free-ranging lion populations, and low-density populations are particularly at risk. we collected data on the prevalence and diversity of viral and parasitic pathogens in a small lion population in eastern botswana. during 2012 and 2014, blood samples were collected from 59% (n=13) of the adult-subadult lions in the nort ...201727669009
prevalence and diversity of babesia, hepatozoon, ehrlichia, and bartonella in wild and domestic carnivores from zambia, africa.a molecular survey was conducted for several hemoparasites of domestic dogs and three species of wild carnivores from two sites in zambia. three babesia spp. were detected including babesia felis and babesia leo in lions (panthera leo) and a babesia sp. (similar to babesia lengau) in spotted hyenas (crocuta crocuta) and a single lion. all wild dogs (lycaon pictus) and domestic dogs were negative for babesia. high prevalences for hepatozoon were noted in all three wild carnivores (38-61%) and in ...201424363181
babesia lengau associated with cerebral and haemolytic babesiosis in two domestic cats.although reported sporadically from various countries, feline babesiosis appears to be a significant clinical entity only in south africa, where babesia felis is usually incriminated as the causative agent. babesia lengau, recently described from asymptomatic cheetahs, has now possibly been incriminated as the causative agent in two severe clinical cases in domestic cats.201323634743
molecular detection of vector-borne pathogens in dogs and cats from qatar.vector-borne diseases (vbds) have been increasingly reported in dogs and cats worldwide. however, no data are currently available regarding canine and feline vbds in qatar and limited information is available from other persian gulf countries.201728633666
epidemiological aspects on vector-borne infections in stray and pet dogs from romania and hungary with focus on babesia spp.canine arthropod-borne infections are of major interest in small animal practice and have been widely investigated in central and western europe. however, only limited epidemiological data are available from south-eastern european countries, although diseases including babesiosis or dirofilariosis are widely recognised as important canine infections in these countries. a steadily increasing number of dogs imported from south-eastern europe into germany require particular attention by small anima ...201121947342
babesiosis in dogs and cats-expanding parasitological and clinical spectra.canine babesiosis caused by different babesia species is a protozoal tick-borne disease with worldwide distribution and global significance. historically, babesia infection in dogs was identified based on the morphologic appearance of the parasite in the erythrocyte. all large forms of babesia were designated babesia canis, whereas all small forms of babesia were considered to be babesia gibsoni. however, the development of molecular methods has demonstrated that other babesia species such as ba ...201121571435
feline babesiosis in south africa: a review.babesia felis, originally identified in wild cats in the sudan, was subsequently found to cause clinical disease in domestic cats. although babesiosis in domestic cats has been reported sporadically from various countries, as a significant disease it appears to be a distinctly south african phenomenon. apart from an inland focus, feline babesiosis is reported regularly only from coastal regions. the infection is assumed to be tick-borne, but the vector has not been identified. feline babesiosis ...200415604490
feline babesiosis: signalment, clinical pathology and concurrent infections.fifty-six cats with naturally occurring babesia felis infection were studied. no breed or sex predilection could be identified, but there was an apparent predilection for young adult cats less than 3 years of age. macrocytic, hypochromic, regenerative anaemia was present in 57% of the cats and in-saline agglutination tests were positive in 16%. no characteristic changes were observed in total or differential leukocyte counts. thrombocyte counts were variable and thrombocytopaenia was an inconsis ...200111563718
chemotherapy of babesia felis infection: efficacy of certain drugs.the efficacy of 10 drugs was tested against babesia felis infection in domestic cats. primaquine phosphate administered per os or as an intramuscular injection was found to be highly effective and the obvious drug of choice when compared with conventional babesicides. the recommended dosage is 0,5 mg/kg body mass of primaquine base. repeated treatments are well tolerated but single doses in excess of 1 mg/kg are known to cause mortality in cats.19817341778
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