| antifungal activity of plant extracts against arthrinium sacchari and chaetomium funicola. | various plant extracts were examined for antifungal activity with the objective of improving the commercial sterility of aseptically filled tea beverage products in pet bottles. when the hot water extract and the methanol extract of 29 samples were measured for their antifungal activity against arthrinium sacchari m001 and chaetomium funicola m002 strains, five samples, acer nikoense, glycyrrhiza glabra, lagerstroemia speciosa, psidium guajava and thea sinensis, showed high activity. of these, t ... | 2000 | 16232887 |
| modulation of expression of il-8 gene in bronchial epithelial cells by 5-methoxypsoralen. | persistent recruitment of neutrophils in the bronchi of cystic fibrosis patients contributes to airway tissue damage, suggesting the importance of intervening on the expression of the neutrophil chemokine il-8. extracts from plants have been investigated to select components able to reduce il-8 expression in bronchial epithelial cells challenged with pseudomonas aeruginosa. extracts and purified components have been added to cells 24 h before pro-inflammatory challenge with p. aeruginosa and il- ... | 2009 | 19720161 |
| inhibitory effects of orobol 7-o-d-glucoside from banaba (lagerstroemia speciosa l.) on human rhinoviruses replication. | the anti-human rhinovirus (hrv) activity of orobol 7-o-d-glucoside (o7g) from lagerstroemia speciosa l. (lythraceae) was evaluated in hela cells. | 2010 | 20497313 |
| Lagerstroemia speciosa fruit extract modulates quorum sensing-controlled virulence factor production and biofilm formation in Pseudomonas aeruginosa. | Lagerstroemia speciosa (Lythraceae), a Southeast Asian tree is more commonly known as "Jarul". Research on health benefits suggests that L. speciosa plant contains phytomolecules which may act as antioxidant, anti-diabetic and anti-obesity. However, antimicrobial activities of this plant are not reported. Potential of L. speciosa fruit extract (LSFE) was evaluated to antagonize cell to cell communication, expression of virulence genes and factors and biofilm formation in Pseudomonas aeruginosa ... | 2011 | 22117007 |
| biofilm inhibition formation of clinical strains of pseudomonas aeruginosa mutans, photocatalytic activity of azo dye and gc-ms analysis of leaves of lagerstroemia speciosa. | the investigation was conducted to analyse the bioactive compounds from the leaf extracts of l. speciosa by gc-ms. the extracts were screened for antibacterial and antibiofilm activities against potential clinical strains. the bioactive compounds from the leaves of l. speciosa were extracted by soxhlet continuous extraction method and their chemical composition was analysed by gas chromatography-mass spectroscopy (gc-ms). the antibacterial activity was evaluated against clinical strain like stap ... | 2017 | 28319869 |
| antibiofilm efficacy of green synthesized graphene oxide-silver nanocomposite using lagerstroemia speciosa floral extract: a comparative study on inhibition of gram-positive and gram-negative biofilms. | biofilm architecture provides bacteria with enhanced antibiotic resistance, thus raising the need to search for alternative therapies that can inhibit the bacterial colonization. in the present study, we synthesized graphene oxide-silver nanocomposite (go-ag) by non-toxic and eco-friendly route using a floral extract of legistromia speciosa (l.) pers. the gas chromatography-mass spectrometry (gc-ms) analysis of plant extract revealed the presence of compounds which can simultaneously act as redu ... | 2017 | 28027944 |
| ellagic acid & gallic acid from lagerstroemia speciosa l. inhibit hiv-1 infection through inhibition of hiv-1 protease & reverse transcriptase activity. | banaba (lagerstroemia speciosa l.) extracts have been used as traditional medicines and are effective in controlling diabetes and obesity. the aim of this study was to evaluate the anti-hiv property of the extracts prepared from the leaves and stems of banaba, and further purification and characterization of the active components. | 2013 | 23640562 |
| phytoremediation of dyes using lagerstroemia speciosa mediated silver nanoparticles and its biofilm activity against clinical strains pseudomonas aeruginosa. | the aim of this study was to prepare silver nanoparticles by a green method using the aqueous leaves extract of lagerstroemia speciosa. the prepared silver nanoparticles were characterized, studied for its photocatalytic and biofilm inhibition studies. the maximum absorbance peak was found at 427nm and thus confirming the formation of silver nanoparticles. the average size of silver nanoparticles synthesized was found to be 12nm using xrd and it was spherical in shape. the nanoparticles synthesi ... | 2017 | 28212517 |
| adverse effects of herbal medicines: an overview of systematic reviews. | this overview of systematic reviews (srs) aims to evaluate critically the evidence regarding the adverse effects of herbal medicines (hms). five electronic databases were searched to identify all relevant srs, with 50 srs of 50 different hms meeting our inclusion criteria. most had only minor weaknesses in methods. serious adverse effects were noted only for four hms: herbae pulvis standardisatus, larrea tridentate, piper methysticum and cassia senna. the most severe adverse effects were liver o ... | 2013 | 23472485 |
| evaluation of toxicity of plant extracts against vector of lymphatic filariasis, culex quinquefasciatus. | conventional insecticides are generally used as larvicides to control culex quinquefasciatus, vector of lymphatic filariasis. this study was undertaken to evaluate the larvicidal activity of some potential larvicidal plants leaf extracts against cx. quinquefasciatus larvae. | 0 | 22561628 |
| a review of the efficacy and safety of banaba (lagerstroemia speciosa l.) and corosolic acid. | banaba (lagerstroemia speciosa l.) extracts have been used for many years in folk medicine to treat diabetes, with the first published research study being reported in 1940. this review summarizes the current literature regarding banaba and its constituents. the hypoglycemic effects of banaba have been attributed to both corosolic acid as well as ellagitannins. studies have been conducted in various animal models, human subjects and in vitro systems using water soluble banaba leaf extracts, coro ... | 2011 | 22095937 |
| glucose-lowering effect of dlbs3233 is mediated through phosphorylation of tyrosine and upregulation of ppar╬│ and glut4 expression. | dlbs3233 is a standardized extract combination containing lagerstroemia speciosa and cinnamomum burmannii. the effect of dlbs3233 on glucose uptake, adiponectin secretion, and insulin signaling was examined in this study. | 2011 | 21674027 |
| antioxidant effect of lagerstroemia speciosa pers (banaba) leaf extract in streptozotocin-induced diabetic mice. | aqueous leaf extract of l. speciosa (banaba) effectively decreased the blood glucose in streptozotocin-induced diabetic mice after 15th day of banaba exposure. further, banaba leaf extract have the potential to inhibit lipid peroxidation and effectively intercept/neutralize reactive oxygen species such as super oxide, h2o2 and no based free radicals. the aqueous banaba leaf extract (150 mg/kg bodyweight) duly reduced stz generated reactive intermediates and radical species helping to regulate no ... | 2011 | 21428214 |
| antioxidant capacities and total phenolic contents of 56 wild fruits from south china. | in order to identify wild fruits possessing high nutraceutical potential, the antioxidant activities of 56 wild fruits from south china were systematically evaluated. the fat-soluble components were extracted with tetrahydrofuran, and the water-soluble ones were extracted with a 50:3.7:46.3 (v/v) methanol-acetic acid-water mixture. the antioxidant capacities of the extracts were evaluated using the ferric reducing antioxidant power (frap) and trolox equivalent antioxidant capacity (teac) assays, ... | 2010 | 21116229 |
| effect of corosolic acid on dietary hypercholesterolemia and hepatic steatosis in kk-ay diabetic mice. | corosolic acid (ca), contained in the leaves of the banaba plant (lagerstroemia speciosa l.), is a pentacyclic triterpene, and has hypoglycemic effects. the effects of ca on dietary hypercholesterolemia and hepatic steatosis were assessed in kk-ay mice, an animal model of type 2 diabetes. two kinds of high cholesterol diet with or without 0.023% ca, were prepared for the study. kk-ay mice were fed a normal diet (controls), the high cholesterol diet with ca (ca-mice) or that without ca (hc-mice) ... | 2010 | 20834178 |
| lagerstroemia speciosa extract inhibit tnf-induced activation of nuclear factor-kappab in rat cardiomyocyte h9c2 cells. | lagerstroemia speciosa has been used as a folk medicine among people with diabetes in the philippines. it is known to exhibit antidiabetic, antiobesity, and glucose transport activities through mechanisms not well defined. diabetes leads to cardiomyocyte hypertrophy in association with an upregulation of vasoactive factors and activation of nuclear factor (nf)-kappab and activating protein-1. we therefore investigated the effect of lagerstroemia speciosa on the activation of nf-kappab as a key m ... | 2010 | 20045454 |
| lc-ms/ms method for the simultaneous determination of ethyl gallate and its major metabolite in rat plasma. | a simple, rapid and sensitive liquid chromatography-tandem mass spectroscopy (lc-ms/ms) method was developed and validated for the determination of ethyl gallate, a pharmacologically active constituent isolated from lagerstroemia speciosa (linn.) pers. this method was used to examine the pharmacokinetics of ethyl gallate and its major metabolite gallic acid in rat plasma using propyl gallate as an internal standard. after precipitation of the plasma proteins with acetonitrile, the analytes were ... | 2010 | 19688816 |
| corosolic acid stimulates osteoblast differentiation by activating transcription factors and map kinases. | recently, the use of anabolic agents to enhance bone mass has been a source of interest. previous work by us suggested that corosolic acid (2alpha-hydroxyursolic acid), an active component of banaba leaves (lagerstroemia speciosa l.), potentially stimulates the differentiation of mouse osteoblasts. therefore, the present study investigated whether corosolic acid stimulates osteoblast differentiation, and its possible mechanisms of action. at low concentrations (up to 5 microm), corosolic acid si ... | 2009 | 19441063 |
| effect of feeding lagerstroemia speciosa and conventional fodder based rations on nutrient utilization, ruminal metabolites and body weight gain in mithun (bos frontalis). | the aim of the present study was to evaluate the effect of feeding green fodder, rice straw and concentrate-based total mixed rations (tmr) on dry matter (dm) intake (dmi), nutrient utilization, rumen fermentation patterns and body weight (bw) gain (bwg) in mithun (bos frontalis) calves. in a randomized block design, male mithun calves (n = 18, 8-10 months of age, 121 +/- 2 kg bw) were randomly divided into three experimental equal groups (six animals in each group) and fed isonitrogenous tmrs a ... | 2008 | 19012603 |
| effect of corosolic acid on the hydrolysis of disaccharides. | the banaba leaf (lagerstroemia speciosa l.) has been used in traditional oriental medicine to treat diabetes in the philippines. it contains corosolic acid (ca), a compound which has a hypoglycemic effect. we examined the effect of ca on blood glucose levels and the hydrolysis of disaccharides in the small intestine in mice. ca (10 mg/kg body weight) improved hyperglycemia after an oral administration of sucrose, and significantly reduced the hydrolysis of sucrose in the small intestine. these r ... | 2008 | 18635916 |
| amelioration of cisplatin induced nephrotoxicity in mice by an ethyl acetate extract of lagerstroemia speciosa (l). | we studied an ethyl acetate (etoac) extract of leaves obtained from the medicinal and ornamental tree, lagerstroemia speciosa l, for nephroprotective activity in cisplatin-induced acute renal injury in balb/c mice. the etoac extract at dose levels of 50 and 250 mg/kg showed a dose-dependent reduction in cisplatin-induced elevations in urea and creatinine concentrations. additionally, treatment with the etoac extract prevented the cisplatin-induced decline of the renal antioxidant enzymes superox ... | 2007 | 18380170 |
| effect of corosolic acid on gluconeogenesis in rat liver. | corosolic acid (cra), an active component of banaba leaves (lagerstroemia speciosa l.), decreases blood glucose in diabetic animals and humans. in this study, we investigated the mechanism of action of cra on gluconeogenesis in rat liver. cra (20-100 microm) dose-dependently decreased gluconeogenesis in perfused liver and in isolated hepatocytes. fructose-2,6-bisphosphate (f-2,6-bp), a gluconeogenic intermediate, plays a critical role in hepatic glucose output by regulating gluconeogenesis and g ... | 2008 | 18177973 |
| novel hosts of the eucalyptus canker pathogen chrysoporthe cubensis and a new chrysoporthe species from colombia. | the pathogen chrysoporthe cubensis (formerly cryphonectria cubensis) is best known for the important canker disease that it causes on eucalyptus species. this fungus is also a pathogen of syzygium aromaticum (clove), which is native to indonesia, and like eucalyptus, is a member of myrtaceae. furthermore, c. cubensis has been found on miconia spp. native to south america and residing in melastomataceae. recent surveys have yielded c. cubensis isolates from new hosts, characterized in this study ... | 2006 | 16876702 |
| bangladeshi medicinal plant extracts inhibiting molecular interactions between nuclear factors and target dna sequences mimicking nf-kappab binding sites. | several medicinal plants can be employed to produce extracts exhibiting biological effects. the aim of this work was to verify the ability of extracts derived from different medicinal plants of bangladesh in interfering with specific dna-protein interactions. the rationale for this study is based on the observation that alteration of gene transcription represents a very promising approach to control the expression of selected genes and could be obtained using different molecules acting on the in ... | 2005 | 16789890 |
| tannic acid stimulates glucose transport and inhibits adipocyte differentiation in 3t3-l1 cells. | obesity is a major risk factor for syndrome x and type ii diabetes (t2d). however, most antidiabetic drugs that are hypoglycemic also promote weight gain, thus alleviating one symptom of t2d while aggravating a major risk factor that leads to t2d. adipogenesis, the differentiation and proliferation of adipocytes, is a major mechanism leading to weight gain and obesity. it is highly desirable to develop pharmaceuticals and treatments for t2d that reduce blood glucose levels without inducing adipo ... | 2005 | 15671208 |
| activation of insulin receptors by lagerstroemin. | lagerstroemin, an ellagitannin isolated from the leaves of lagerstroemia speciosa (l.) pers. (lythraceae), was examined for its biological activities. in rat adipocytes, the compound increased the rate of glucose uptake and decreased the isoproterenol-induced glycerol release. in chinese hamster ovary cells expressing human insulin receptors, it increased the erk activity. these insulin-like actions were accompanied by the increased tyrosine-phosphorylation of the beta-subunit of the insulin rec ... | 2003 | 14501154 |
| identification of pyrogallol as an antiproliferative compound present in extracts from the medicinal plant emblica officinalis: effects on in vitro cell growth of human tumor cell lines. | in this study we compared the in vitro antiproliferative activity of extracts from medicinal plants toward human tumor cell lines, including human erythromyeloid k562, b-lymphoid raji, t-lymphoid jurkat, erythroleukemic hel cell lines. extracts from emblica officinalis were the most active in inhibiting in vitro cell proliferation, after comparison to those from terminalia arjuna, aphanamixis polystachya, oroxylum indicum, cuscuta reflexa, aegle marmelos, saraca asoka, rumex maritimus, lagerstro ... | 2002 | 12063567 |
| ellagitannins from lagerstroemia speciosa as activators of glucose transport in fat cells. | glucose transport enhancers were searched for in lagerstroemia speciosa, a philippine local herbal medicine used for diabetes mellitus. bioassay-guided fractionation of the aqueous acetone extract of the leaves afforded three active ellagitannins, lagerstroemin, flosin b and reginin a, identified by nmr and optical rotation. these compounds increased glucose uptake of rat adipocytes, and could be responsible for lowering the blood glucose level. | 2002 | 11859474 |
| an extract of lagerstroemia speciosa l. has insulin-like glucose uptake-stimulatory and adipocyte differentiation-inhibitory activities in 3t3-l1 cells. | the effects of extracts isolated from lagerstroemia speciosa l. (banaba) on glucose transport and adipocyte differentiation in 3t3-l1 cells were studied. glucose uptake-inducing activity of banaba extract (be) was investigated in differentiated adipocytes using a radioactive assay, and the ability of be to induce differentiation in preadipocytes was examined by northern and western blot analyses. the hot water be and the banaba methanol eluent (bme) stimulated glucose uptake in 3t3-l1 adipocytes ... | 2001 | 11533261 |
| alpha-amylase inhibitory activity of some malaysian plants used to treat diabetes; with particular reference to phyllanthus amarus. | extracts of six selected malaysian plants with a reputation of usefulness in treating diabetes were examined for alpha-amylase inhibition using an in vitro model. inhibitory activity studied by two different protocols (with and without pre-incubation) showed that phyllanthus amarus hexane extract had alpha-amylase inhibitory properties. hexane and dichloromethane extracts of anacardium occidentale, lagerstroemia speciosa, averrhoa bilimbipithecellobium jiringa and parkia speciosa were not active ... | 2006 | 16678367 |
| in vitro cytotoxic, antioxidative and alpha-glucosidase inhibitory potential of a herbal mixture comprised of allium sativum and lagerstroemia speciosa. | hyperglycemia induced over production of free radicals in the mitochondrial electron transport chain is now considered as one of the central mechanisms in the pathogenesis of diabetic complications. allium sativum and lagerstroemia speciosa contains active principles possessing anti-diabetic and antioxidant properties. this study is aimed at evaluating the evidence that supports this traditional claim and investigates the possible synergistic effect on these herbs when given as a herbal mixture ... | 2012 | 22957419 |
| dia-2, a polyherbal formulation ameliorates hyperglycemia and protein-oxidation without increasing the body weight in type ii diabetic rats. | the dried bulbs of allium sativum (garlic) and leaves of lagerstroemia speciosa (banaba) are used as medicinal food for the treatment of diabetes and other ailments. | 2013 | 23426539 |
| herbal formulation, dia-2 and rosiglitazone ameliorates hyperglycemia and hepatic steatosis in type 2 diabetic rats. | dia-2 is a herbal mixture containing standardized extract of allium sativum and lagerstroemia speciosa. recently we have reported the anti-diabetic effect of dia-2 in high fat diet (hfd) and streptozotocin (stz) induced type 2 diabetic (t2d) rats. the purpose of this study was to investigate and compare the effects of dia-2 with rosiglitazone (rg) on plasma biomarkers of hepatocellular injury, liver carbohydrate metabolizing enzymes, glycogen content, oxidant/antioxidant status and histopatholog ... | 2015 | 26367735 |
| assessment of air pollution stress on some commonly grown tree species in industrial zone of durgapur, west bengal, india. | the present study deals with the biochemical responses of some selected tree species with respect to increased air pollution in durgapur industrial city in india. areas in vicinity to industries possess very high concentrations of suspended particulate matter (571 microg/m3), sox (132 microg/m3) and nox (97 microg/m3) which shows significant correlations (p < 0.05) with the biochemical constituents of stressed plants. plants growing in industrial zone exhibit a considerable decline in total chlo ... | 2011 | 22324147 |
| in vitro thrombolytic potential of root extracts of four medicinal plants available in bangladesh. | thrombus formation inside the blood vessels obstructs blood flow through the circulatory system leading hypertension, stroke to the heart, anoxia, and so on. thrombolytic drugs are widely used for the management of cerebral venous sinus thrombosis patients, but they have certain limitations. medicinal plants and their components possessing antithrombotic activity have been reported before. however, plants that could be used for thrombolysis has not been reported so far. | 2014 | 25538351 |
| toxicity studies on herbal formulation used in diabetes mellitus. | in current study herbal formulation was prepared for diabetes mellitus (type 2). it consists of the extracts of salacia reticulate, cinnamomum zeylanicum,lagerstroemia speciosa, camellia sinensis and gymnema sylvester. toxicitystudies were carried out on heart, liver, kidney and blood of both male and female rabbits. drug was administered in a dose of 15mg/kg body weight daily for 90 days. on 91th day, blood was drawn from animals and investigated for changes in biochemical and hematological lev ... | 2014 | 26045373 |
| iqp-gc-101 reduces body weight and body fat mass: a randomized, double-blind, placebo-controlled study. | iqp-gc-101 is a patented blend of the standardized extracts of garcinia cambogia, camellia sinensis, unroasted coffea arabica, and lagerstroemia speciosa. these individual ingredients of iqp-gc-101 have each shown promise in promoting weight loss; however, the efficacy of the blend has not been established. this randomized, placebo-controlled, double-blind, parallel group study conducted over 14 weeks (including a 2-week run-in phase) aimed to investigate the efficacy and safety of iqp-gc-101 in ... | 2014 | 24797657 |
| screening for potential α-glucosidase and α-amylase inhibitory constituents from selected vietnamese plants used to treat type 2 diabetes. | the 18 plant species investigated in this study have been used as herbal antidiabetic remedies in vietnamese traditional medicines. this study aimed to evaluate their ability to inhibit α-glucosidase and α-amylase, two key enzymes involved in serum glucose regulation. | 2016 | 27041401 |
| a simple gc-ms method for the screening of betulinic, corosolic, maslinic, oleanolic and ursolic acid contents in commercial botanicals used as food supplement ingredients. | the occurrence of triterpene pentacyclic acids in plants is extensive, but little is known about their availability in commercial extracts. a simple gc-ms method for the simultaneous determination of betulinic, corosolic, maslinic, oleanolic and ursolic acids was developed and applied to 38 different commercial plant extracts sold as ingredients for dietary supplements. a suitable protocol was set up to perform routine control of a diverse array of samples with different botanical, chemical and ... | 2013 | 23122121 |