| ackertia globulosa sp. n. (nematoda: filarioidea) from rodents in kenya. | ackertia globulosa sp. n. (nematoda: filarioidea) is described from the pulmonary arteries of the striped mouse, lemniscomys striatus striatus (l.), in kenya. distinguishing features are the small size of the adults; the short left spicule and arrangement of the caudal papillae (3 pairs preanal, 4 pairs postanal) of the male; small projecting lobes on the tail of the females; and 10 to 12 refractile globules in the microfilarial sheath. the microfilariae are found in the skin, mostly of the ear. ... | 1975 | 1165543 |
| the murid filaria monanema martini: a model for onchocerciasis. part i. description of lesions. | a study of the anatomo-pathological lesions induced by monanema martini, a filaria with skin-dwelling microfilariae, was performed using 65 lemniscomys striatus fixed from 30 minutes to 36 months after inoculation of the infective larvae, 5 arvicanthis niloticus and 3 meriones unguiculatus fixed during the patent phase, and controls. attempts at quantification of lesions in l. striatus was made. approximately 20% of l. striatus had microfilariae in the eyeballs, and many more presented ocular le ... | 1991 | 1776782 |
| the fate of the filaria monanema martini in two rodent hosts: recovery rate, migration, and localization. | in meriones unguiculatus, the recovery rate of 80 inoculated larvae was low (about 20%) and irregular. in the natural host lemniscomys striatus, the recovery rate was about 50% with inoculated doses of 30, 80 or 400 l3, but slightly higher for 400 l3. this rate was constant from day 2 to month 8 post infection (p.i.). when 7-9 reinoculations were performed in one year, the recovery rate of the late inoculation was of only 14%. after subcutaneous inoculations, larvae penetrated into the peripheri ... | 1990 | 2221759 |
| the skin-dwelling microfilariae of monanema martini in lemniscomys striatus as potential drug screening model for onchocerciasis: midazolam effect in vitro. | the murid model of monanema martini in lemniscomys striatus was used to evaluate its potential as drug screening model in onchocerciasis. it had been described that the histopathology and the reaction to diethylcarbamazine treatment of this model closely resemble human onchocerciasis. to study further similarities the in vitro effect of midazolam was examined. skin-dwelling microfilariae (mf) of m. martini were taken by skin snips and placed in either plain phosphat buffered saline or midazolam. ... | 1988 | 2907264 |
| [cutaneous changes induced by a dose of dec in rodents with skin microfilaria: relevance of these phenomena for understanding the mazzotti reaction and the pathogenesis of human onchocerciasis]. | a single dose of dec was given to lemniscomys striatus parasitized by monanema martini. the histopathological analysis of ear-lobe skin sections shows: a massive escape of microfilariae from the lymph capillaries, a major vascular exudative reaction with edema and diapedesis of blood cells. this inflammatory process leads to the destruction of the extralymphatic microfilariae and it induces a subacute and chronic dermatitis at the 7th day. these findings explain the pathogenesis of mazzotti reac ... | 1987 | 3103881 |
| [anatomo-pathologic study of skin and ocular lesions in rodents infested by monanema spp.: significance for the study of human onchocerciasis]. | skin and ocular lesions were studied in murids lemniscomys striatus l. infested by 2 isolates of monanema spp, a rodent filaria with skin-dwelling microfilariae. histologic examination disclosed microfilariae in lymphatic vessels. penetration of microfilariae in extra-vascular tissues caused vascular changes, subacute inflammatory cells infiltration, granulomatous nodules and scarring lesions. these alterations corresponded to the successive stages of an inflammatory process. no correlation note ... | 1986 | 3813417 |
| [a filaria of african muridae in the wall of the colon: monanema martini n. sp]. | description of m. martini n. sp. (= m. nilotica el bihari et al., 1977 sensu bain et coll., 1985), a parasite of arvicanthis niloticus from mali. the natural host is arvicanthis niloticus from mali; the description is based on material from experimentally infected laboratory-bred rodents (holotype from a. niloticus; other specimens from lemniscomys striatus). like other related species the microfilariae of m. martini are said to be "skin dwelling" (in fact they are in cutaneous lymphatic vessels ... | 1986 | 3813428 |
| [comparative study of the cutaneous and ocular lesions of murids lemniscomys striatus parasitized by monanema spp. and atherurus africanus parasitized by cercopithifilaria sp. with those of human onchocercosis]. | histologic examination of skin and ocular lesions in various rodents infested by various species of filariae with skin-dwelling microfilariae disclosed very similar aspects as compared to lesions noted in human onchocerciasis: coexistence in the same organ of five following types of lesion: vascular changes; subacute inflammatory cells infiltration; granulomatous lesions; scarring alterations; vascular ectasia. | 1985 | 3933783 |
| [experimental transmission of monanema nilotica el bihari & coll., 1977, a filaria with skin-dwelling microfilaria parasitic in african murids]. | the value of monanema of murids as experimental models of ocular lesions due to onchocerciasis would be greatly increased if we could experiment with several host and parasite species since, in many cases, the lesions induced are more significant when the host-parasite association is poorly adapted. the life cycle of 2 isolates of monanema nilotica is completed, one from lemniscomys striatus from the central african republique and the other from arvicanthis niloticus of mali. as in m. globulosa, ... | 1985 | 3985535 |
| ophthalmological study of the lesions induced by the filarial worm with dermal microfilariae, monanema martini, in its murid hosts. | the filaria monanema martini with skin-dwelling microfilariae induces in its natural murid hosts lesions similar to those in human onchocerciasis. this was demonstrated by histo-pathological studies but it appeared useful to evaluate the model by a clinical investigation. an ophthalmological analysis was performed on the two species of hosts, inoculated by one, two, or multiple doses of larvae, and with infections of at least one year duration. a total of 140 eyes was examined (anterior and post ... | 1993 | 8293664 |
| ivermectin and moxidectin in two filarial systems: resistance of monanema martini; inhibition of litomosoides sigmodontis insemination. | effects of ivermectin and moxidectin were compared on two filarial species: monanema martini which presents dermal microfilariae and induces onchocerca-like lesions in its natural murid host lemniscomys striatus, and litomosoides sigmodontis (= l. carinii). m. martini microfilariae showed an unusual resistance to ivermectin, in vitro and in vivo; moxidectin was no more efficient. however, the two drugs used at high concentrations deeply altered the uterine embryogenesis, but had no lethal effect ... | 1997 | 9419842 |
| eimeria telekii n.sp. (apicomplexa: coccidia) from lemniscomys striatus (rodentia: muridae): morphology, pathology and phylogeny. | using a combination of morphological, life-cycle and molecular data, we describe a new apicomplexan parasite eimeria telekii n.sp. from a striped grass mouse lemniscomys striatus captured in kenya. oocysts are oval to spherical or ellipsoidal, 20.4 x 15.7 (15.5-25.0 x 12.0-20.0) microm with a colourless, smooth and bilayered wall. sporocysts are ellipsoidal, 11.2 x 7.8 (10.0-12.0 x 7.0-9.0) microm with a small stieda body and granular sporocyst residuum and contain 2 elongated, banana-shaped spo ... | 2001 | 11272644 |
| isolation and characterization of flagellates from rodents and canids in masinga, machakos district, kenya. | a total of 728 animals comprising of 633 rodents and 95 canids were examined for leishmanial parasites. flagellates were isolated from 67 out of 111 (60.4%) acomys subspinosus (spiny mouse), 12 out of 143 (8.4% ) mastomys natalensis (multimammate rat), 2 out of 50 (4.0%) lemniscomys striatus (striped mouse), 2 out of 6 (33.3%) herpestes sanguineus (slender mongoose), 1 of 1 helogale parvula (dwarf mongoose) and 1 out of 84 canis familiaris (domestic dog). all isolates were characterized by isoen ... | 1995 | 12160424 |
| ectoparasites (sucking lice, fleas and ticks) of small mammals in southeastern kenya. | during 1998-2000, at least 14 species (n = 309) of small mammals were live-trapped and examined for ectoparasites in moist forests of the taita and shimba hills and drier savannah habitats of nguruman, southeastern kenya. ectoparasites were recorded from 11 species of mammals. five species of sucking lice [hoplopleura inexpectans johnson, h. intermedia kellogg & ferris, polyplax reclinata (nitzsch), p. waterstoni bedford and schizophthirus graphiuri ferris], six species of fleas (ctenophthalmus ... | 2009 | 19941604 |
| lassa serology in natural populations of rodents and horizontal transmission. | lassa virus causes hemorrhagic fever in west africa. previously, we demonstrated by pcr screening that only the multimammate mouse, mastomys natalensis, hosts lassa virus in guinea. in the present study, we used the same specimen collection from 17 villages in coastal, upper, and forest guinea to investigate the lassa virus serology in the rodent population. the aim was to determine the dynamics of antibody development in m. natalensis and to detect potential spillover infections in other rodent ... | 2014 | 25229705 |
| monanema martini in its murid hosts: microfiladermia related to infective larvae and adult filariae. | the microfiladermia of monanema martini was studied in two natural murid hosts, lemniscomys striatus and arvicanthis niloticus, with 137 and 39 rodents respectively inoculated once, twice or several times. microfilarial densities (mf/mm2) were measured at the ear pinna every three months. almost all the rodents developed a microfiladermia. when l. striatus rodents were inoculated once with 30, 80, or 400 infective larvae, microfiladermia increased (peaks of 108, 148, 174 mf/mm2 respectively, at ... | 1994 | 7939158 |
| plague in tanzania: an overview. | human plague remains a public health concern in tanzania despite its quiescence in most foci for years, considering the recurrence nature of the disease. despite the long-standing history of this problem, there have not been recent reviews of the current knowledge on plague in tanzania. this work aimed at providing a current overview of plague in tanzania in terms of its introduction, potential reservoirs, possible causes of plague persistence and repeated outbreaks in the country. plague is bel ... | 2013 | 26591701 |
| spatio-temporal variation in small mammal species richness, relative abundance and body mass reveal changes in a coastal wetland ecosystem in ghana. | coastal wetlands in ghana are under severe threat of anthropogenic drivers of habitat degradation and climate change, thereby increasing the need for assessment and monitoring to inform targeted and effective conservation of these ecosystems. here, we assess small mammal species richness, relative abundance and body mass in three habitats at the muni-pomadze ramsar site of ghana, and compare these to baseline data gathered in 1997 to evaluate changes in the wetland ecosystem. small mammals were ... | 2016 | 27154051 |
| prevalence and diversity of small mammal-associated bartonella species in rural and urban kenya. | several rodent-associated bartonella species are human pathogens but little is known about their epidemiology. we trapped rodents and shrews around human habitations at two sites in kenya (rural asembo and urban kibera) to determine the prevalence of bartonella infection. bartonella were detected by culture in five of seven host species. in kibera, 60% of rattus rattus were positive, as compared to 13% in asembo. bartonella were also detected in c. olivieri (7%), lemniscomys striatus (50%), mast ... | 2015 | 25781015 |
| movement patterns of small rodents in lassa fever-endemic villages in guinea. | the natal multimammate mouse (mastomys natalensis) is the reservoir host of lassa arenavirus, the etiological agent of lassa fever in humans. because there exists no vaccine for human use, rodent control and adjusting human behavior are currently considered to be the only options for lassa fever control. in order to develop efficient rodent control programs, more information about the host's ecology is needed. in this study, we investigated the spatial behavior of m. natalensis and other small r ... | 2018 | 29572697 |