| a comparative study of the effects of venoms from five rear-fanged snake species on the growth of leishmania major: identification of a protein with inhibitory activity against the parasite. | leishmania parasites of several species cause cutaneous and visceral disease to millions of people worldwide, and treatment for this vector-borne protozoan parasite typically involves administration of highly toxic antimonial drugs. snake venoms are one of the most concentrated enzyme sources in nature, displaying a broad range of biological effects, and several drugs now used in humans were derived from venoms. in this study, we compared the effects of the venoms of the south american rear-fang ... | 2011 | 21601589 |
| venom proteomes of south and north american opisthoglyphous (colubridae and dipsadidae) snake species: a preliminary approach to understanding their biological roles. | opisthoglyphous snake venoms remain under-explored despite being promising sources for ecological, evolutionary and biomedical/biotechnological research. herein, we compared the protein composition and enzymatic properties of the venoms of philodryas baroni (pbv), philodryas olfersii olfersii (poov) and philodryas patagoniensis (ppv) from south america, and hypsiglena torquata texana (httv) and trimorphodon biscutatus lambda (tblv) from north america. all venoms degraded azocasein, and this meta ... | 2012 | 22974712 |
| subcutaneous compliance and gravitational adaptation in snakes. | previous studies have implicated morphological adaptations as important counter-measures to gravitational stresses on the circulatory systems of arboreal or climbing snakes. such features include tight skin and relatively non-compliant tissue compartments that oppose edema formation, but these traits have not been previously studied quantitatively. to provide information on this subject, interstitial fluid pressures were measured in eleven species of snakes using slit-end catheters positioned in ... | 1993 | 8277230 |
| biochemical and biological analysis of philodryas baroni (baron's green racer; dipsadidae) venom: relevance to the findings of human risk assessment. | philodryas baroni--an attractively colored snake--has become readily available through the exotic pet trade. most people consider this species harmless; however, it has already caused human envenomation. as little is known about the venom from this south american opisthoglyphous "colubrid" snake, herein, we studied its protein composition by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (sds-page), as well as its effects on the hemostatic system. both reducing and nonreducing sds-pag ... | 2014 | 23800999 |