| efficiency of different agrobacterium rhizogenes strains on hairy roots induction in solanum mammosum. | this article presents the abilities and efficiencies of five different strains of agrobacterium rhizogenes (strain atcc 31798, atcc 43057, ar12, a4 and a13) to induce hairy roots on solanum mammosum through genetic transformation. there is significant difference in the transformation efficiency (average number of days of hairy root induction) and transformation frequency for all strains of a. rhizogenes (p < 0.05). both a. rhizogenes strain ar12 and a13 were able to induce hairy root at 6 days o ... | 2013 | 23090845 |
| comparative proteomic analysis of indioside d-triggered cell death in hela cells. | medicinal plants represent a rich source of cancer drug leads. indioside d, a furostanol glycoside isolated from solanum mammosum, was found to possess antiproliferative activity toward a panel of human cancer cell lines. proteomic analysis of indioside d-treated hela cells revealed profound protein changes related to energy production and oxidative stress, suggesting that mitochondria dysfunction plays a role in indioside d-induced apoptosis. indioside d caused a rapid dissipation of mitochondr ... | 2008 | 18376857 |
| the search for natural bioactive compounds through a multidisciplinary approach in bolivia. part ii. antimalarial activity of some plants used by mosetene indians. | forty-six different species collected in the mosetene ethnia, dwelling in the andean piedmont of bolivia, were screened for antimalarial properties. thirty-three extracts were screened for antimalarial activity in vitro on plasmodium falciparum chloroquine resistant strain (indo), and forty-seven extracts were evaluated in vivo on the rodent malaria p. vinckei petteri 279by. only two plants are specifically used in combination by the mosetene against malaria attack (hymenachne donacifolia and te ... | 2000 | 10687870 |