| allee effects within small populations of aconitum napellus ssp. lusitanicum, a protected subspecies in northern france. | plants growing at low density can suffer from allee effects as a result of pollen limitation. previous studies of allee effects have focused on the effects of variation among populations in size or density on reproduction. here, the effects of plant distribution within populations on fitness components are explored in a rare plant, aconitum napellus ssp. lusitanicum, and ecological and genetic mechanisms underlying these effects are identified. to detect pollen limitation, seed production was co ... | 2008 | 18557816 |
| salade malade: malignant ventricular arrhythmias due to an accidental intoxication with aconitum napellus. | intoxication with aconitum napellus is rare in our regions. aconite alkaloids can cause ventricular arrhythmia by a prolonged activation of sodium channels. because the margin of safety is low between the analgesic and toxic dose, intoxication is not rare when aconite is used in herbal medicine. we present a case in which a 39-year-old male was accidentally intoxicated with aconite. even though no antidote or adequate therapy is available he was successfully resuscitated. (neth heart j 2008;16:9 ... | 2008 | 18345331 |
| malignant ventricular arrhythmias due to aconitum napellus root. | | 2009 | 19124940 |
| dpph radical scavenging activity of two flavonol glycosides from aconitum napellus sp. lusitanicum. | the dpph radical scavenging activity of two flavonol glycosides obtained from ethanolic extracts of aconitum napellus sp. lusitanicum was studied. the results showed a high dpph antiradical activity of compound 1 (quercetin 3-o-(6-trans-caffeoyl)-beta-glucopyranosyl-(1-->2)-beta-glucopyranosyl-7-o-alpha-rhamnopyranoside) when compared with compound 2 (quercetin-3-sophoroside-7-rhamnopyranoside), rutin and ascorbic acid. the relationship between the caffeoyl and rhamnopyranoside groups in the fla ... | 2006 | 16828239 |
| [poisoning with aconitum napellus (monkshood)]. | a lethal case of aconite poisoning due to ingestion of pieces of monkshood (aconitum napellus) is described. | 2003 | 12812106 |
| response to paper 'malignant ventricular arrhythmias due to aconitum napellus root'. | | 2009 | 19212028 |
| establishment of zygomorphy on an ontogenic spiral and evolution of perianth in the tribe delphinieae (ranunculaceae). | ranunculaceae presents both ancestral and derived floral traits for eudicots, and as such is of potential interest to understand key steps involved in the evolution of zygomorphy in eudicots. zygomorphy evolved once in ranunculaceae, in the speciose and derived tribe delphinieae. this tribe consists of two genera (aconitum and delphinium s.l.) comprising more than one-quarter of the species of the family. in this paper, the establishment of zygomorphy during development was investigated to cast ... | 2009 | 19608573 |
| toxicology in the old testament. did the high priest alcimus die of acute aconitine poisoning? | the bible contains several interesting contributions to the history of neurology, as is the case of the high priest alkimos, who died suddenly in 159 bc. he was regarded as a stereotypical stroke victim for a long time. the reports on his death in the septauginta and the later 'jewish antiquities' of flavius josephus present some typical symptoms of stroke (collapse, loss of speech and death within a short time), but they also describe severe pains, which are very unusual among patients with str ... | 2002 | 12298423 |
| flavonoids from aconitum napellus subsp. neomontanum. | three flavonol glycosides quercetin 7-o-(6-trans-caffeoyl)-beta-glucopyranosyl-(1-->3)-alpha-rhamnopyranoside-3-o-beta-glucopyranoside (1), kaempferol 7-o-(6-trans-caffeoyl)-beta-glucopyranosyl-(1-->3)-alpha-rhamnopyranoside-3-o-beta-glucopyranoside (2), and kaempferol 7-o-(6-trans-p-coumaroyl)-beta-glucopyranosyl-(1-->3)-alpha-rhamnopyranoside-3-o-beta-glucopyranoside (3), together with the known beta-3,4-dihydroxyphenethyl beta-glucopyranoside, were isolated from the flowers of aconitum napell ... | 2001 | 11394854 |
| test of a homeopathic dilution of aconitum napellus. a clinical, randomized, double-blind, controlled crossover study in healthy volunteers. | although healthy persons often report on reactions to homeopathically diluted substances, the mechanism behind such reactions remains unclear. this study examines whether a distinction can be made between the short-term reactions of healthy volunteers to a homeopathically diluted substance - aconitum napellus c30 - and to a placebo. | 2009 | 19657201 |
| [intoxication with monkshood (aconitum napellus)]. | three patients presented with an intoxication caused by aconitum napellus, commonly known as aconite, monkshood or wolfsbane. the first patient, a woman aged 24, was resuscitated after accidental ingestion of plant material 'from nature'. she experienced severe ventricular tachyarrhythmias. after discharge she returned with identical symptoms, which were now interpreted as intentional intoxication in a suicide attempt. she was referred to the psychiatry department. the second patient was a 2-yea ... | 2009 | 19785799 |
| on: piltan d, rist l, simões-wüst a, saller r: test of a homeopathic dilution of aconitum napellus. a clinical, randomized, double-blind, controlled crossover study in healthy volunteers. forsch komplementmed 2009;16:168-173. | | 2009 | 19887816 |
| anatomical structure of aconitum napellus over ground part and subterranean organs. | | 2010 | 20506815 |
| an exploratory study on scientific investigations in homeopathy using medical analyzer. | the action of homeopathic medicines, in ultra-high dilution, is not directly observable. an attempt was made to explore autonomic response of selective homeopathic medicines, in healthy persons, using medical analyzer system (electronics division, bhabha atomic research centre, mumbai, india). | 2011 | 21787219 |
| fatal aconitine intoxication or thyroid storm? a case report. | the case of a female in the latter half of her teens found dead in her father's apartment is reported. a glass containing liquid and plant remnants was found at the death scene. there were no indications of any intervention or the application of force by a third party. autopsy showed unremarkable findings. toxicological investigations revealed lethal doses of aconitine, a highly poisonous alkaloid and the major active compound of aconitum napellus, in all specimens. plant remnants were identifie ... | 2012 | 22342148 |
| [herbs and cardiotoxic effects]. | accidental or deliberate ingestion of poisonous herbs has become an increasingly common phenomenon over the last years. from existing literature data and case reports from emergency room visits or poison control centers, an overview is presented of the potential cardiotoxic manifestations following intoxication by wild herbal plants of the territory. the effects of the consumption of cardiac glycoside-containing plants (e.g., digitalis) are discussed along with tachyarrhythmias induced by aconit ... | 2013 | 23748541 |
| quantification of aconitine in post-mortem specimens by validated liquid chromatography-tandem mass spectrometry method: three case reports on fatal 'monkshood' poisoning. | the diester-diterpene alkaloid aconitine was quantified by liquid chromatography-tandem mass spectrometry in post-mortem specimens of three cases where suicidal ingestion of aconitum napellus l. ('monkshood') was supposed. in an attempt at rationalization, sample preparation and chromatographic conditions of plasma/serum drug analysis routine were utilized. linearity was established from 0.5 to 20 µg l⁻¹ using newborn calf serum (ncs) as a surrogate calibration matrix for all sample types and me ... | 2016 | 23749589 |
| [fatal exposure to aconitum napellus]. | fatal exposure to poisonous plants in northern europe is a rare condition. in this case report we describe an intended poisoning with aconitum napellus (monkshood), which contains the toxin aconitine. the lethal dose in adults is 3-6 mg. the toxin affects excitable cells such as neurons and myocytes causing degrees of unconsciousness, hypotension and cardiac arrhythmias. there is no antidote and treatment is symptomatic. we describe a patient who had eaten monkshood. she was treated with infusio ... | 2013 | 23763930 |
| identification of diterpene alkaloids from aconitum napellus subsp. firmum and girk channel activities of some aconitum alkaloids. | diterpene alkaloids neoline (1), napelline (2), isotalatizidine (3), karakoline (4), senbusine a (5), senbusine c (6), aconitine (7) and taurenine (8) were identified from aconitum napellus l. subsp. firmum, four (2-4, 6) of which are reported for the first time from this plant. the structures were determined by means of lc-ms, 1d and 2d nmr spectroscopy, including (1)h-(1)h cosy, noesy, hsqc and hmbc experiments. electrophysiological effects of the isolated compounds, together with nine diterpe ... | 2013 | 23876370 |
| effects of flowering plant's patch size on species composition of pollinator communities, foraging strategies, and resource partitioning in bumblebees (hymenoptera: apidae). | in 4 common middle-european mainly bumblebee-pollinated plant species (impatiens glandulifera, echium vulgare, aconitum napellus, symphytum officinale) the influence of patch size on species composition of the pollinator community was studied. short-tongued species were most dominant in large patches, while small patches were frequented by middle- and long-tongued bumblebees. this phenomenon was extremely obvious in symphytum officinale and aconitum napellus, where short-tongued species had bitt ... | 1989 | 28312186 |
| a study of the diterpene alkaloids of aconitum napellus ssp. neomontanum during its onthogenetic cycle. | qualitative and quantitative variations in the diterpene alkaloids content in the neomontanum subspecies of aconitum napellus, growing near lake of como, were studied throughout its complete onthogenetic cycle. aconitine, n-deethylaconitine and two compounds with m.w. = 688 and m.w. = 629 have been detected in the various organs of plant almost at any time during the vegetative cycle. | 1988 | 3247340 |
| comparison of homeopathic globules prepared from high and ultra-high dilutions of various starting materials by ultraviolet light spectroscopy. | homeopathic globules are commonly used in clinical practice, while research focuses on liquid potencies. sequential dilution and succussion in their production process has been proposed to change the physico-chemical properties of the solvent(s). it has been reported that aqueous potencies of various starting materials showed significant differences in ultraviolet light transmission compared to controls and between different dilution levels. the aim of the present study was to repeat and expand ... | 2016 | 26860812 |
| a case of fatal aconitine poisoning by monkshood ingestion. | accidental aconitine poisoning is extremely rare in north america. this report describes the confirmation of a case of accidental aconitine poisoning using a liquid chromatography-tandem mass spectrometry (lc-ms/ms) method. the case involved a 25-year-old man who died suddenly following a recreational outing with friends where he consumed a number of wild berries and plants including one that was later identified as monkshood (aconitum napellus). postmortem blood and urine samples were available ... | 2008 | 18284527 |
| severe acute poisoning with homemade aconitum napellus capsules: toxicokinetic and clinical data. | aconitum napellus is an extremely dangerous plant that contains various toxic diterpenoid alkaloids, mainly aconitine primarily concentrated in the roots. we report a case of acute intoxication of a 21-year-old man admitted to our emergency department after the ingestion, in order to sleep, of three homemade aconitum napellus capsules. capsules were measured to contain 237 mg of root and 19 microg of aconitine. the patient experienced the first symptoms on wakening 5 hours later with generalized ... | 2005 | 16440517 |
| [organic acids in the tubers & leaves of aconitum napellus]. | | 1958 | 13606607 |
| [soluble carbohydrates and heterosides in the leaves of aconitum napellus l]. | | 1958 | 13571743 |
| [chemical and biological research on the alkaloid content of aconitum napellus l. flowers and tubers in relation to altitude]. | | 1957 | 13459618 |
| [structural characteristics of the tuberous roots of aconitum napellus l..]. | | 2006 | 14391614 |
| [quantitative determination of acotinine in aconitum napellus tincture]. | | 1955 | 13258312 |
| [effects of external factors on the content of active principle in medicinal plants. ii. effects of climate on the alkaloid content of aconitum napellus]. | | 1953 | 13055415 |
| [physiological testing of aconitine (aconitum napellus l)]. | | 1951 | 14915297 |
| the anticancer homeopathic composite "canova method" is not genotoxic for human lymphocytes in vitro. | the canova method (cm) is a homeopathic medicine indicated for the treatment of patients with cancer and for pathologies that involve a depressed immune system, such as aids. this product is composed of homeopathic dilutions of aconitum napellus, arsenicum album (arsenic trioxide), bryonia alba, lachesis muta venom and thuya occidentalis. it stimulates the immune system by activating macrophages. activated macrophages stimulate the lymphocytes so that they increase their cytotoxic action in resp ... | 2003 | 14966688 |
| [serious plant poisonings in switzerland 1966-1994. case analysis from the swiss toxicology information center]. | to analyze the types, frequency and severity of plant poisonings in switzerland over 29 years. | 1996 | 8711457 |
| a case of fatal poisoning with the aconite plant: quantitative analysis in biological fluid. | in recent years recorded cases of plant poisoning have become rare, this may in part be due to the possibility of plant ingestion not being indicated at the beginning of an investigation. aconitum napellus (aconite, wolfsbane, monkshood) is one of the most poisonous plants in the uk. it contains various potent alkaloids such as aconitine, isoaconitine, lycaconitine and napelline. ingestion of aconitum plant extracts can result in severe, potentially fatal toxic effects. this paper describes the ... | 2015 | 12407981 |
| [long qrs tachycardia secondary to aconitum napellus alkaloid ingestion]. | the roots and seeds of the aconite (aconitum napellus) contain alkaloids with modulatory activity on the sodium voltage-dependent channels; most fatal cases have been determined by ventricular tachycardia and respiratory paralysis. the only established treatment is supportive. we report a case of poisoning from aconitum napellus, ingested by a husband and wife who thought the plant was "mountain chicory". they both had tachyarrhythmias, but the husband had more malignant episodes of hemodynamica ... | 2002 | 12407844 |
| new flavonol glycosides from the flowers of aconitum napellus ssp. tauricum. | from the methanolic extract of the flowers of a. napellus spp. tauricum four new flavonol glycosides: quercetin 3-o-(6-trans-caffeoyl)-beta-glucopyranosyl-(1-->2)-beta-glucopyranoside-7- o-alpha-rhamnopyranoside (1), kaempferol 3-o-(6-trans-caffeoyl)-beta-glucopyranosyl-(1-->2)-beta- glucopyranoside-7-o-alpha-rhamnopyranoside (2), quercetin 3-o-(6-trans-p-coumaroyl)-beta-glucopyranosyl-(1-->2)-beta- glucopyranoside-7-o-alpha-rhamnopyranoside (3), and kaempferol 3-o-(6-trans-p-coumaroyl)-beta-glu ... | 2001 | 11345707 |
| malignant ventricular arrhythmias due to aconitum napellus seeds. | | 2000 | 11104752 |
| isolation of diterpenoid alkaloids from herb and flowers of aconitum napellus ssp. vulgare and electrospray ion trap multiple ms study of these alkaloids | chemical investigation of herb and flowers of aconitum napellus l. ssp. vulgare led to the isolation of 12 diterpenoid alkaloids. their chemical structures were identified on the basis of nmr and ms and of their complete ion trap multiple fragmentation mass spectrometry study. | 1999 | 10346949 |
| the homoeopathic treatment of otitis media in children--comparisons with conventional therapy. | in a prospective observational study carried out by 1 homoeopathic and 4 conventional ent practitioners, the 2 methods of treating acute pediatric otitis media were compared. group a received treatment with homoeopathic single remedies (aconitum napellus, apis mellifica, belladonna, capsicum, chamomilla, kalium bichromicum, lachesis, lycopodium, mercurius solubilis, okoubaka, pulsatilla, silicea), whereas group b received nasal drops, antibiotics, secretolytics and/or antipyretics. the main outc ... | 1997 | 9247843 |
| [toxicity of monkshood. review.]. | monkshood, aconitum napellus l. (ranunculaceae), is considered one of the most poisonous plants growing in europe. monkshood and other aconitum species are still used in oriental and homeopathic medicine as analgesics, febrifuges and hypotensives. the neurotoxin aconitine is the principal alkaloid in most subspecies of monkshood. a review is presented, which includes historical aspects of monkshood as a poisonous and medicinal plant, the mode of action of aconitine, symptoms of toxicity, treatme ... | 1997 | 19679935 |
| [acute otitis media in children. comparison between conventional and homeopathic therapy]. | within a prospective group study of five practicing otorhinolaryngologists, conventional therapy of acute otitis media in children was compared with homeopathic treatments. group a (103 children) was primarily treated with homeopathic single remedies (aconitum napellus, apis mellifica, belladonna, capsicum, chamomilla, kalium bichromicum, lachesis, lycopodium, mercurius solubilis, okoubaka, pulsatilla, silicea). group b (28 children) was treated by decongestant nose-drops, antibiotics, secretoly ... | 1996 | 8805013 |
| norditerpenoid alkaloids from aconitum napellus ssp. neomontanum. | | 1996 | 17252442 |
| improvement of aconitum napellus micropropagation by liquid culture on floating membrane rafts. | an efficient method was developed using floating membrane rafts (liferaft(™)) for the micropropagation of aconitum napellus (ranunculaceae), a cut flower crop with a low natural propagation rate. this was achieved by introducing shoot tips into culture on murashige and skoog's (1962) solid medium, or liquid medium-supported rafts, supplemented by different levels of benzyl adenine (ba). optimum shoot proliferation on solid medium required 4mg/l ba, whereas for expiants supported on rafts optimal ... | 1995 | 24185330 |
| aconitine in nectaries and other organs from an icelandic population of aconitum napellus ssp. vulgare. | | 1994 | 17236049 |
| [fatal poisoning caused by aconite monk's hood (aconitum napellus)]. | severe intoxications after ingestion of monk's hood are rare in childhood. we report a case of fatal intoxication in a 20 months old child. there is no specific therapy available. a review of the literature is added. | 1991 | 1896051 |
| resource heterogeneity and patterns of movement in foraging bumblebees. | differences in the foraging behavior of b. terricola workers on white clover, trifolium repens, were examined on previously unvisited (filled) and depleted flowers, and as a function of flower-head density. 1. the number of florets visited per unit time was independent of flower head density from 20 to at least 290 heads/m(2), in part because the bees utilized more florets per head at low flower head densities, and also because they approached but rejected more flower heads at high rather than a ... | 1979 | 28309608 |
| [high-dose magnesium sulfate in the treatment of aconite poisoning]. | this article reports the case of a 62-year-old male patient who ingested the roots of monkshood (aconitum napellus) and white hellebore (veratrum album) dissolved in alcohol with a suicidal intention and suffered cardiotoxic and neurotoxic symptoms. after contacting the poison information centre ventricular arrhythmia was treated with high-dose magnesium sulphate as the only antiarrhythmic agent and subsequently a stable sinus rhythm could be established after approximately 3 h. aconitum napellu ... | 2015 | 25812545 |
| nonomuraea flavida sp. nov., a novel species of soil actinomycete isolated from aconitum napellus rhizosphere. | a novel actinomycete strain, yn-5-1t, isolated from the rhizosphere soil of a medicinal plant, aconitum napellus, was characterized by a polyphasic approach to determine its taxonomic position. the strain showed highest 16s rrna gene sequence similarities of 97.3, 97.2 and 97.1 % to nonomuraea turkmeniaca dsm 43926t, nonomuraea ferruginea dsm 43553t and nonomuraea candida dsm 45086t, respectively. a wide range of genotypic and phenotypic characteristics, as well as levels of dna-dna relatedness ... | 2015 | 26289724 |
| dna-based identification of peucedanum ostruthium specimens and detection of common adulterants by high-resolution melting curve analysis. | masterwort (peucedanum ostruthium, syn. imperatoria ostruthium, apiaceae) is an old economic plant in alpine countries cultivated as ornamental plant and used for spirits and in folk medicine. p. ostruthium is a species that has often been confused with related apiaceae species or morphologically similar roots or tubers resulting in products of minor quality. masterwort can be distinguished from other apiaceae species by nrdna (its1 and its2). the analysed chloroplast markers (trnk 5' intron, tr ... | 2015 | 26493217 |
| [on the presence and distribution of aminophenols (tyramine, 3-hydroxy-tyramine or dopamine, and noradrenaline) in monkshood: aconitum napellus l]. | | 1967 | 4964603 |
| circadian aspects of hyperthermia in mice induced by aconitum napellus. | aconitum napellus (acn) is used topically to relieve pain, itching and inflammation, and internally to reduce febrile states, among others. any circadian time-related consequences of acn administration are unknown. the objective of this study was to explore the effects of two doses of acn on body temperature (bt) of mice treated at six different times over 24 hours. | 2011 | 21969795 |
| acute toxic herbal intake in a suicide attempt and fatal refractory ventricular arrhythmia. | this report involves a 54-year-old man who died following refractory ventricular fibrillation after ingestion of a plant in a suicide attempt. repeated direct-current cardioversions were unsuccessful and no single anti-arrhythmic agent was effective for arrhythmia control. the routine blood toxicological screening was negative. aconitine, the main toxin of aconitum napellus was identified using a specific liquid chromatography-tandem mass spectrometry (lc-ms/ms) method. the whole blood concentra ... | 2010 | 20353487 |
| biological and molecular characterization of a new carlavirus isolated from an aconitum sp. | abstract a new virus was isolated from symptomless aconitum napellus plants. the virus, for which the name aconitum latent virus (aclv) is proposed, has flexuous particles 640 nm in length. the experimental host range was limited to nicotiana clevelandii. electron microscopy studies of ultrathin sections of infected a. napellus tissues revealed the presence of elongated virus particles. no inclusion bodies characteristic of potyvirus infection were observed. aclv was purified from naturally infe ... | 2000 | 18944582 |
| [medicinal and poisonous plants. vii. aconitum napellus]. | | 1962 | 14462504 |
| antipyretic studies on some indigenous pakistani medicinal plants: ii. | eight pakistani medicinal plants were investigated for antipyretic activity in rabbits receiving subcutaneous yeast injections. hexane- and chloroform-soluble extracts of aconitum napellus stems, corchorus depressus whole plant and gmelina asiatica roots exhibited prominent oral antipyretic activity while insignificant antipyretic effects were found in the hexane- and chloroform-soluble portions of melia azadirachta seeds, tinospora cordifolia stems and vitex trifolia seeds. no antipyretic actio ... | 1987 | 3497307 |