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numerical taxonomy of actinomadura and related actinomycetes.one hundred and fifty-six actinomadura strains, marker strains of related taxa, and related isolates from bagasse and fodder were the subject of numerical phenetic analyses using 90 unit characters. the data were examined using the simple matching (ssm), jaccard (sj) and pattern (dp) coefficients and clustering was achieved using both single and average linkage algorithms. cluster composition was not markedly affected either by the coefficient or clustering algorithms used or by test error, esti ...1979479835
[the role of histopathology in the diagnosis of mycetomas. two cases of maduromycosis. actinomadura pelletieri and leptosphaeria tompkinsii (author's transl)]. 1978686856
red grain mycetoma of the scalp (actinomadura pelletieri). a case report from india.a case of red grain mycetoma on the scalp is described. the disease, caused by actinomadura pelletieri, is extremely rare in this part of the world, and from india this is perhaps the first case with scalp involvement. the lesion showed satisfactory response to partial excision followed by chemotherapy with streptomycin.1978692630
distribution of menaquinones in actinomycetes and corynebacteria.menaquinones were the only isoprenoid quinones found in 48 corynebacteria and actinomycete strains examined. dihydromenaquinones having nine isoprene units were the main components isolated from gordona, mycobacterium, corynebacterium bovis, corynebacterium glutamicum and a strain labelled nocardia farcinica, but dihydromenaquinones having eight isoprene units were characteristic of other corynebacterium species and representatives of the 'rhodochrous' complex. tetrahydromenaquinones having six ...1977894261
comparison of antigens from agents of actinomycetoma by immunodiffusion and electrophoresis procedures.antigenic extracts were prepared from culture filtrates of the principal agents known to cause actinomycetoma, namely actinomadura madurae, actinomadura pelletieri, nocardia asteroides, nocardia brasiliensis, nocardia otitidis-caviarum, and streptomyces somaliensis. these antigenic preparations were compared by immunodiffusion (id), counterimmunoelectrophoresis (cie), line immunoelectrophoresis (lie) and rocket line immunoelectrophoresis (rlie), with rabbit antisera prepared against each of the ...19902126557
red grain mycetoma of the scalp due to actinomadura pelletieri in madurai. 19902132513
mm 46115, a new antiviral antibiotic from actinomadura pelletieri. characteristics of the producing cultures, fermentation, isolation, physico-chemical and biological properties.six strains of actinomadura pelletieri were shown to produce a novel macrolide antibiotic, designated mm 46115. mm 46115 was active against parainfluenza virus 1 and 2 and gram-positive bacteria. methods are described for the production of mm 46115 by strain ip 729.63, and for the isolation of the compound from a butanol extract of the culture filtrate.19902177052
mycetoma in the republic of niger: clinical features and epidemiology.mycetoma is a common disease in the republic of niger. in two hospitals 133 cases were observed. the major site of lesions was the foot. actinomycetomata were seen more often than eumycetomata. streptomyces somaliensis is prevalent in the north desert zone while actinomadura pelletieri is common in the southern part of the country. madurella mycetomatis, the usual etiologic agent of eumycetoma, is seen in both regions. the species incidence and distribution in niger differs from those of the wes ...19883354772
[epidemiologic study of mycetomas in mexico. apropos of 502 cases].the epidemiological data of 502 mycetomas studied in the department of mycology, "centro dermatológico pascua", mexico city, were analysed. mycetomas prevail in males (79.7%), they are more frequent between 16 and 45 years of age (75%) and among rural workers (62.5%); they preferentially affect lower limbs (62.5%); these data are generally similar to the known publications on the matter. actinomycetomas are the most frequent with 97.2% of the cases, distributed as follows: nocardia: 85.6% among ...19873621395
actinomadura pelletieri mycetoma from the transvaal. a case report.the osteophilic red grain mycetoma due to actinomadura pelletieri is rare in southern africa. this report describes an elderly patient with extensive bone involvement in which lymphatic spread to the inguinal lymph nodes had occurred. the diagnosis and management are discussed.19854035517
[63 cases of mycetoma in the niger republic (etiological study based on histopathology)].63 samples of mycetomas were examined between 1981 and 1984. most of them (53 cases) were actinomycotic mycetomas of which 20 were due to streptomyces somaliensis, 17 to actinomadura pelletieri, 11 to nocardia sp., 4 to actinomadura madurae. the 11 mycotic mycetomas were all due to madurella mycetomi (= m. mycetomatis).19854085097
mycetoma mandibularis due to nocardia pelletieri. 19734753643
prodigiosin-like pigments from actinomadura (nocardia) pelletieri. 19715132249
mycetoma caused by nocardia pelletieri in the united states. 19695780962
prodigiosin-like pigments from actinomadura (nocardia) pelletieri and actinomadura madurae.thirteen red strains of actinomadura (nocardia) pelletieri and three of a. madurae were shown to produce prodigiosin-like pigments. both of the two major pigments which were observed on thin-layer chromatograms had r(f) values significantly greater than prodigiosin. the main pigment from a. madurae 953 was shown by mass and nuclear magnetic resonance spectroscopies to be nonylprodigiosin. the major pigment from a. pellitieri had a c(11)h(22) side chain in a ring form, but it was distinctly diffe ...19695803627
molecular-genetic and chemotaxonomic studies on actinomadura and nocardiopsis.the relationships of 24 strains of 13 species of actinomadura and 4 strains of nocardiopsis dassonvillei were determined by nucleic acid hybridization studies. dna-rrna cistron similarity and dna homology values reveal that actinomadura is genetically heterogeneous. one cluster contained the type species actinomadura madurae, actinomadura pelletieri, actinomadura verrucosospora, actinomadura malachitica, actinomadura citrea and 'actinomadura kijaniata'. a second cluster embraced actinomadura pus ...19836198437
sugar-containing lipids in the classification of representative actinomadura and nocardiopsis species.the major sugar-containing lipids of some actinomadura and nocardiopis strains--recognized as an important agent of actinomycetoma -- were analyzed by thin-layer and gas-liquid chromatography. it was demonstrated that nocardiopsis dassonvillei strains contained two characteristic glycolipids identified as monomannosyl diglyceride and monoacylated glucose. none of them was found in the representatives of actinomadura madurae and actinomadura pelletieri strains, which possessed phosphatidylinosito ...19836651478
numerical classification of sporoactinomycetes containing meso-diaminopimelic acid in the cell wall.one hundred and thirty actinomycetes representing 19 genera and 50 species were compared in a numerical phenetic survey using 108 unit characters. data were examined using the simple matching (ssm), jaccard (sj) and pattern (dp) coefficients and clustering was achieved using both the single and unweighted pair group average algorithms. cluster composition was barely affected by the statistics used or by test error, estimated at 2.1%. over 80% of the strains were assigned to 2 clusters containing ...19827077300
a preliminary study on the ultrastructure of actinomadura pelletieri and its host tissue reaction.this is the first report on the fine structure of actinomadura pelletieri. the in vitro ultrastructure of the organism and that of the grain in vivo were similar. the grain consisted of packed filaments with a faintly electron-dense matrix in between. the individual filament was septate, the cytoplasm was either vacuolated or contained intracellular organelles and the cytoplasmic membrane was adherent to the filamentous wall, which has three electron-dense and two electron-lucent layers. the abs ...19947844700
[actinomycotic mycetoma. apropos of 27 cases in dakar; medical treatment with cotrimoxazole].actinomycotic mycetoma is frequent in senegal and the treatment has changed greatly over the last decades. we observed 27 cases due to actinomadura pelletieri (n = 21), actinomadura madurae (n = 5) and streptomyces somaliensis (n = 1). the diagnosis was based on clinical and histological arguments. all the patients were treated with cotrimoxazole for several months. the mycetoma was situated on the foot in 15/27 patients. extrapodal localizations were frequent for red grains due to a. pelletieri ...19947979030
red grain mycetoma caused by actinomadura pelletieri in western rajasthan: report of two cases. 19938157323
polyphasic taxonomic study of clinically significant actinomadurae including the description of actinomadura latina sp.nov.thirty-one strains received either as actinomadura madurae or actinomadura pelletieri were assigned to four phena, clusters 1 to 4, in a numerical phenetic survey of the genus actinomadura. clusters 2 and 4 corresponded to the validly described species a. madurae and a. pelletieri whereas clusters 1 and 3 encompassed strains received as a. madurae and a. pelletieri, respectively. the two clusters that contained a. madurae strains formed a single taxon when a dataset lacking the antibiotic sensit ...19979060154
[mycetoma: 130 cases].mycetoma is a pathological process in which eumycotic (fungal) or actinomycotic causative agents from exogenous source produce grains. it follows penetrating injury inoculating soil organisms, occurring preferentially in rural areas usually among labourers who work barefoot. mycetoma is a localized chronic, and deforming infectious disease of subcutaneous tissues, skin and bones. we report 130 cases of mycetoma in senegal from 1983 to 2000.200312605151
numerical phenetic classification of clinically significant aerobic sporoactinomycetes and related organisms.clinically significant aerobic sporoactinomycetes, notably agents of mycetoma, were examined for a balanced set of unit characters and the resultant data analysed using standard numerical taxonomic procedures. all save two of the one hundred and seventy three tested strains were assigned to three multimembered cluster-groups, which encompassed sixteen major (4-7 strains), ten minor (2-3 strains) and forty single membered clusters, in an analysis based on the simple matching coefficient and unwei ...200312906361
mycetoma caused by a new red grain mycetoma agent in two members of a family.an 18-year-old woman from rural west bengal was affected with mycetoma involving her neck, back, and chest. after an interval of eight years, her younger brother developed mycetoma on his left arm. no history of trauma or immune deficiency was present in either case. by microscopic examination of sinus-discharged materials from both the cases, identical rusty red, hard grains were demonstrated. soluble red pigment-producing colonies grew in sabouraud dextrose-agar medium. isolates were positive ...200314699230
[management of mycetoma in west-africa].mycetoma is still endemic in the northern areas of west-africa. this infection is more common in males, rural inhabitants, between 20 and 40 years of age. mycetoma is generally easy to identify on clinical presentation, it is a chronic subcutaneous inflammatory tumor with discharging sinuses. the commonest affected site is the foot (70%), leg, knee, thigh, hand and arm are the most frequent extrapodal localizations. diagnosis must be confirmed by the presence of grains at direct and histological ...200315015843
[actinomycetomas in senegal: study of 90 cases].mycetoma is a pathological process during which eumycetomic (fungal) or actinomycotic causative agents from exogenous source produce grains. medical treatment is available for actinomycetomas and surgery is still the main treatment for eumycetoma. we report 90 cases of actinomycetoma occuring in male adult patients coming mainly from central senegal. patients living far from health structures consult after a long evolution period for tumors and pains which prevent them from carrying out their ac ...200515915967
[cranial and cervical vertebral mycetoma. report of three cases].mycetomas inflammatory-like tumors presenting as fistulas found in the skin and soft tissues. inoculation, generally in tropical areas, occurs by skin injury. the foot is the main infection site. other uncommon infection sites include the cranial and cervical areas which are rare. we present three cases of cranial and cervical mycetoma. clinical sign were dominated by headache, cervical pain and cervico-occipital tumefaction with formation of pus and granules (red in two cases, black in one). a ...200516327680
majority of actinomadura clinical isolates from sputa or bronchoalveolar lavage fluid in japan belongs to the cluster of actinomadura cremea and actinomadura nitritigenes, and the description of actinomadura chibensis sp. nov.in japan during 1996-2004, 21 actinomycete strains that have madurose as the diagnostic cell-wall sugar and show true branching in their substrate and aerial mycelia were isolated from sputa or bronchoalveolar lavage (bal) fluid of patients with pulmonary infections or who were suspected of having related infections. chemotaxonomic studies showed that all the isolates belong to the genus actinomadura. among them, six and seven strains were classified respectively into clusters of actinomadura ni ...200617039274
red grain botryomycosis due to staphylococcus aureus--a novel case report.staphylococcus aureus and some other bacteria are known to cause botryomycosis. these bacteria are known to produce yellowish-white soft grains. only actinomadura pelletieri is known to produce red grains. we report here a case of an intensely inflammatory type of botryomycosis. a 35-year-old male labourer presented with swelling, redness and multiple sinuses on his foot, of eight months duration. the purulent discharge contained bright red coloured grains, 0.5 to 1 mm in size, which were round ...200919736413
mycetoma in south india: retrospective analysis of 13 cases and description of two cases caused by unusual pathogens: neoscytalidium dimidiatum and aspergillus flavus.mycetoma is a chronic suppurative and/or granulomatous inflammatory lesion of skin, subcutaneous tissue, fascia, and tendons caused by the traumatic inoculation of either fungal (eumycotic) or bacterial (actinomycotic) organisms present in the soil. the disease is characterized by triad of tumefaction, discharging sinuses, and grains.201020964650
actinomadura pelletieri mycetoma--an atypical case with spine and abdominal wall involvement.we describe a case of mycetoma caused by actinomadura pelletieri with simultaneous involvement of the spine, abdominal wall and retroperitoneal space in a man who had suffered from 'madura foot' 10 years earlier. the characteristics of this case were analysed and contextualized among those of other cases of mycetoma caused by other micro-organisms found through a review of the international literature. the rarity of the disease in industrialized countries and its possible atypical presentations ...201121252272
actinomadura meridiana sp. nov., isolated from oreum (small mountain).a new actinomycete, designated strain dls-45t, was from a soil of rock surface collected from the peak of darangshi oreum (small mountain) in jeju, republic of korea. substrate mycelium was well developed but aerial mycelium was scant on most of the media. spherical to subspherical spores on the aerial mycelium were in chains that were arranged in hooks and their surfaces were warty. the combination of morphological and chemical features supported the classification in the genus actinomadura. th ...201121398504
global burden of human mycetoma: a systematic review and meta-analysis.mycetoma is a chronic infectious disease of the subcutaneous tissue with a high morbidity. this disease has been reported from countries between 30°n and 15°s since 1840 but the exact burden of disease is not known. it is currently unknown what the incidence, prevalence and the number of reported cases per year per country is. in order to estimate what the global burden of mycetoma is, a meta-analysis was performed. in total 50 studies were included, which resulted in a total of 8763 mycetoma ca ...201324244780
[mycetomas diagnosed in senegal from 2008 to 2010].mycetomas are inflammatory pseudotumours of subcutaneous and possibly osseous soft fabrics, generally polyfistulas with chronic mode of evolution.201124451559
[a dorsolumbar tumoral actinomycosic mycetoma, an unusual mycetoma presentation].mycetomas are localized chronic inflammatory infectious diseases involving subcutaneous tissues, skin and bones. we report a case of mycetoma in a 40-year-old farmer from the north of senegal. the clinical appearance of the lesions suggested primarily the diagnosis of a soft tissue malignant tumor. mycetoma diagnosis was confirmed by histopathologic evidences and growth of actinomadura pelletieri in cultured samples. the evolution was good under a triple antibiotic therapy combining cotrimoxazol ...201424387810
actinomadura pelle171eri causing white grain mycetoma.actinomadura pelletieri causing white grain mycetoma pedis in a 32 year old farmer is reported. the right foot was swollen, firm painless, non tender and had a number of small nodules breaking down to form sinuses. the seropurulent discharge contained dirty white grains measuring 0.5 to 1 mm, composed of unfragmented filaments of bacterial width. histologic examination of the biopsy material revealed the characteristic granule of a. pelletieri and culture yielded typical coral red colonies.201728176747
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