| possible origins and evolution of the hepatitis b virus (hbv). | all members of the family hepadnaviridae are primarily viruses which contain double-stranded dna genomes that are replicated via reverse transcription of a pregenomic rna template. there are two subgroups within this family: mammalian and avian. the avian member's include the duck hepatitis b virus (dhbv), heron hepatitis b virus, ross goose hepatitis b virus, stork hepatitis b virus and the recently identified parrot hepatitis b virus. more recently, the detection of endogenous avian hepadnavir ... | 2013 | 24013024 |
| a non-human hepadnaviral adjuvant for hepatitis c virus-based genetic vaccines. | human hepatitis b virus (hbv) core antigen (hbcag) can act as an adjuvant in hepatitis c virus (hcv)-based dna vaccines. since two billion people are, or have been, in contact with hbv, one may question the use of human hbv sequences as adjuvant. we herein evaluated non-human stork hepatitis b virus core gene-sequences from stork as dna vaccine adjuvants. full-length and fragmented stork hbcag gene-sequences were added to an hcv non-structural (ns) 3/4a gene (ns3/4a-stork-hbcag). this resulted i ... | 2016 | 27109565 |