| the nucleotide sequence and reading frames of a mutant hepatitis b virus subtype adr. | | 1989 | 2928116 |
| the nucleotide sequence of surface antigen gene of hepatitis b virus subtype adr. | the nucleotide sequence of the xhoi-bamhi fragment (1279bp), which contains the surface antigen gene (s gene) of hbvadr, was determined by maxam and gilbert's method. by comparing the differences both of the nucleotide sequence in the s gene and its coded amino acid sequence between adr and those reported for adw, ayw and adyw, some new variation sites were discovered. the differences were mainly distributed in the two hydrophilic regions. however, at those sites which might show biological func ... | 1984 | 6098013 |
| cloning and structural analyses of hepatitis b virus dnas, subtype adr. | entire genomes of hepatitis b virus (subtype adr) have been cloned. the nucleotide sequence data were compared with other sequences of hbv genome including: adw [valenzuela et al. (1981) in animal virus genetics. fields et al. eds. academic press, inc., ny. pp. 57-70], ayw [galibert et al. (1979) nature, 281, 646-650], and adyw [pasek et al. (1979) nature 282, 575-579]. four open coding frames for polypeptides larger than 6,000 dalton were found to be conserved and were highly compressed by over ... | 1983 | 6306594 |
| structural analysis of the gene coding for hepatitis b virus surface antigen and its product. | the entire genome of hepatitis b virus (subtype adr) has been cloned into pbr322. the clones could be classified into at least seven groups by their restriction endonuclease cleavage maps. the nucleotide sequences of the hepatitis b surface antigen (hbsag)-coding regions for five clones were determined and compared with published sequences of the hbsag gene including those of adw, ayw, adyw and adr. the 13 available versions of the amino acid sequence of the polypeptide, predicted from the nucle ... | 1985 | 3968537 |
| the complete nucleotide sequence of the cloned dna of hepatitis b virus subtype adr in padr-1. | the complete nucleotide sequence of the cloned hepatitis b virus dna subtype adr in padr-1 was determined by maxam and gilbert's method. it is 3215 base pairs in size, which is 27 bp longer than the sequence of the adr phbr330, as reported by ono et al. the nucleotide difference between padr-1 and adr phbr330 is about 2% while those between padr-1 and adw as well as ayw are 9.3% and 9.7% respectively. in this paper, the heterogeneity and homogeneity of the s gene, the c gene and the other coding ... | 1987 | 3672100 |
| a clone of hepatitis b virus (subtype adr) dna with a new hindiii site. | we have cloned the hbv genome subtype adr through its hindiii site into plasmid pbr322. twelve recombinant plasmids each with an insert of the hbv genome were obtained. the restriction map of one of the recombinants, plasmid padr-h1, was analyzed. the location of the sites for bamhi, bgli, bglii, sstii, xbai and xhoi in padr-h1 were found to be the same as that in padr-1, but the hindiii site of padr-h1 is distinctly different from that of padr-1. the bamhi-hindiii fragment is 316 bp long in the ... | 1985 | 3010452 |
| large hepatitis b surface antigen polypeptides of dane particles with the receptor for polymerized human serum albumin. | large hepatitis b surface antigen polypeptides with apparent molecular sizes of 39,000 and 43,000 daltons (p39 and p43) were liberated from a purified preparation of dane particles of subtype adr. they were tested for reactivity with monoclonal antibodies raised against three synthetic oligopeptides representing fundamental sequences of the pre-s region in deoxyribonucleic acid of hepatitis b virus (subtype adr), as well as with monoclonal antibody against the major surface antigen polypeptide ( ... | 1986 | 3002898 |