Publications

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gestation period in neotoma mexicana. 19685670811
discovery of an enzootic cycle of borrelia burgdorferi in neotoma mexicana and ixodes spinipalpis from northern colorado, an area where lyme disease is nonendemic.an intensive enzootic cycle of borrelia burgdorferi was seen in populations of the mexican wood rat, neotoma mexicana, and ixodes spinipalpis ticks in northern colorado. cultures of rodent ear tissue and ticks yielded 63 spirochetal isolates: 38 n. mexicana, 2 peromyscus difficilis, and 23 i. spinipalpis. all 63 isolates were identified as b. burgdorferi sensu lato by polymerase chain reaction; a representative subset was characterized as b. burgdorferi by sds-page and immunoblotting. a tick-der ...19948077722
genetic identification of a novel hantavirus of the harvest mouse reithrodontomys megalotis.we have cloned the s genomic segment of a novel hantavirus of the harvest mouse reithrodontomys megalotis. the virus is phylogenetically distinct from other hantaviruses. the new hantavirus was identified in harvest mice separated by approximately 1,000 km. a wood rat (neotoma mexicana) was found to be infected with the harvest mouse hantavirus.19948084007
flea (siphonaptera:ceratophyllidae, hystrichopsyllidae) and tick (acarina:ixodidae) control on wood rats using host-targeted liquid permethrin in bait tubes.the efficacy of a liquid permethrin-treated bait tube controlling fleas and ticks on mexican wood rats, neotoma mexicana baird, was evaluated during a 1-yr study in north-central colorado. results indicated that the bait tubes were effective for reducing flea and tick infestations on wood rats. the effects of treatment persisted throughout the study, despite the fact that bait tubes were replenished with bait and permethrin only during the first 4 mo (4 replenishments). our results suggest that ...19979086710
vector competence of ixodes scapularis, i. spinipalpis, and dermacentor andersoni (acari:ixodidae) in transmitting borrelia burgdorferi, the etiologic agent of lyme disease.this report describes the vector competence of 3 ixodid tick species, ixodes scapularis (say), i. spinipalpis (nuttall), and dermacentor andersoni (stiles), for borrelia burgdorferi in colorado. the study was based on preliminary field work performed in 6 colorado counties, where rodents and ticks were collected and assayed for the presence of b. burgdorferi. four of the 6 counties produced 52 rodent and 39 i. spinipalpis isolates of b. burgdorferi. two b. burgdorferi isolates were tested under ...19979103755
culturing selects for specific genotypes of borrelia burgdorferi in an enzootic cycle in colorado.in colorado, borrelia burgdorferi sensu stricto, the etiologic agent of lyme disease, is maintained in an enzootic cycle between ixodes spinipalpis ticks and neotoma mexicana rats (27). the frequencies of flagellin (fla), 66-kda protein (p66), and outer surface protein a (ospa) alleles were examined in 71 b. burgdorferi isolates from samples from colorado. approximately two-thirds of these samples were isolates from i. spinipalpis ticks that had been cultured in bsk-h medium prior to dna extract ...19979276416
population genetics and phylogenetic analysis of colorado borrelia burgdorferi.borrelia burgdorferi is transmitted in an enzootic cycle in colorado between the tick ixodes spinipalpis and the woodrat neotoma mexicana. the genetic relationship of colorado isolates to other b. burgdorferi isolates is unknown nor have relationships among various colorado isolates been determined. portions of the flagellin (fla), 66-kd protein, and outer surface protein a (ospa) genes were amplified from 71 colorado isolates, screened for genetic variability using single strand conformation po ...199910348251
transmission of the agent of human granulocytic ehrlichiosis by ixodes spinipalpis ticks: evidence of an enzootic cycle of dual infection with borrelia burgdorferi in northern colorado.previous work described an enzootic cycle of borrelia burgdorferi sensu lato (hereafter referred to as b. burgdorferi) maintained by the rodent neotoma mexicana and the tick ixodes spinipalpis in northern colorado. we investigated the incidence of coinfection among rodents with the agent of human granulocytic ehrlichiosis (aohge). aohge was detected in 23.5% of 119 rodent spleens examined. biopsy results indicated that 78 (65.5%) of the 119 rodents were positive for b. burgdorferi, whereas 22 (7 ...200010915099
nutritional studies with the white-throated wood rat (neotoma mexicana). 195413205186
ecological connectivity of trypanosoma cruzi reservoirs and triatoma pallidipennis hosts in an anthropogenic landscape with endemic chagas disease.traditional methods for chagas disease prevention are targeted at domestic vector reduction, as well as control of transfusion and maternal-fetal transmission. population connectivity of trypanosoma cruzi-infected vectors and hosts, among sylvatic, ecotone and domestic habitats could jeopardize targeted efforts to reduce human exposure. this connectivity was evaluated in a mexican community with reports of high vector infestation, human infection, and chagas disease, surrounded by agricultural a ...201223049923
diversity among tacaribe serocomplex viruses (family arenaviridae) naturally associated with the mexican woodrat (neotoma mexicana).the results of analyses of glycoprotein precursor and nucleocapsid protein gene sequences indicated that an arenavirus isolated from a mexican woodrat (neotoma mexicana) captured in arizona is a strain of a novel species (proposed name skinner tank virus) and that arenaviruses isolated from mexican woodrats captured in colorado, new mexico, and utah are strains of whitewater arroyo virus or species phylogenetically closely related to whitewater arroyo virus. pairwise comparisons of glycoprotein ...200818304671
novel potential reservoirs for borrelia sp. and the agent of human granulocytic ehrlichiosis in colorado.previous work demonstrated that ixodes spinipalpis ticks maintained an enzootic cycle of borrelia bissettii and the agent of human granulocytic ehrlichiosis (aohge) within woodrats (neotoma mexicana) and deer mice (peromyscus maniculatus) in northern colorado (usa). because i. spinipalpis is the only known vector of b. bissettii and aohge in colorado, this study was designed to determine the reservoir status of other hosts of i. spinipalpis in five distinct ecological zones along the front range ...200212038153
experimental studies of st. louis encephalitis virus in vertebrates.serologically negative birds and mammals of species, known from other studies to be exposed naturally to st. louis encephalitis (sle) virus in memphis, tennessee, and other selected species were inoculated experimentally with strains of sle virus to determine their potential as natural hosts. mosquitoes (culex sp.) were allowed to feed on some of the inoculated vertebrate species, held for 14 days, and tested for sle infection. the cardinals (richmondena cardinalis), robins (turdus migratorius), ...19853999258
serological and virological evidence of a hantaan virus-related enzootic in the united states.the first isolation of a hantaan-related virus from a feral rat in the united states was made from a rattus norvegicus caught in new orleans. the strain, designated tchoupitoulas virus, is antigenically related to, but distinct from, the prototype strain 76-118 of hantaan virus and is the first hantaan-like virus isolated from the pancreas of a naturally infected animal. serosurveys of wild rodents from urban and rural areas in the united states indicated that hantaan-related viruses infected ur ...19852861241
new host and locality records of coccidia (apicomplexa: eimeriidae) from rodents in the southwestern and western united states.one hundred forty-seven murid and heteromyid rodents were collected from various sites in the southwestern and western united states (arizona, colorado, new mexico, texas, and utah) and baja california norte, mexico, and their feces were examined for coccidial parasites. of these, 53 (36%) were infected with at least 1 coccidian; 45 of 53 (85%) of the infected rodents harbored only 1 species of coccidian. infected rodents included: 10 of 22 (45%) neotoma albigula, 3 of 11 (27%) neotoma floridana ...19911779282
cross-transmission studies with eimeria arizonensis-like oocysts (apicomplexa) in new world rodents of the genera baiomys, neotoma, onychomys, peromyscus, and reithrodontomys (muridae).cross-transmission experiments were performed using oocysts of an eimeria arizonensis-like coccidian from peromyscus leucopus and peromyscus truei, an e. arizonensis-like coccidian from reithrodontomys fulvescens, eimeria baiomysis and eimeria taylori from baiomys taylori, eimeria albigulae from neotoma albigula, and eimeria onychomysis from onychomys spp., between representatives of the above host genera. the e. arizonensis-like coccidian from r. fulvescens infected reithrodontomys megalotis, r ...19921597781
borrelia bissettiae sp. nov. and borrelia californiensis sp. nov. prevail in diverse enzootic transmission cycles.two borrelia species, borrelia bissettiae sp. nov. and borrelia californiensis sp. nov., were first described by postic and co-workers (postic et al., 2007; postic et al., 1998) based on genetic analyses of several loci. multilocus sequence analysis (mlsa) of eight housekeeping loci confirmed that these two borrelia genospecies are distinct members of the b. burgdorferi s. l. complex (margos et al., 2010). b. bissettiae sp. nov. initially was described in transmission cycles involving neotoma fu ...201626813420
oxalate digestibility in neotoma albigula and neotoma mexicana.the cactus specialist, neotoma albigula, tolerates high concentrations of potentially harmful oxalate compounds in its diet. previous research has shown that oxalate compounds are broken down by intestinal micro-organisms. thus the ability of n. albigula to utilize a diet high in oxalates may be a consequence of the adaptation of the microflora rather than its own evolution. to test this hypothesis, the oxalate degradation ability of n. albigula was compared with that of n. mexicana, a generalis ...198528311315
epizootiology of arenaviral infections in the white-throated woodrat (muridae: sigmodontinae) and other woodrats in arizona.the purpose of this study was to extend and refine our knowledge of the geographical distribution and natural host relationships of the arenaviruses associated with woodrats indigenous to arizona. antibody to a tacaribe serocomplex virus was found in 112 of 1,250 white-throated woodrats, five of 208 mexican woodrats, one of 114 stephen's woodrats, and none of 862 other rodents captured at 51 sites in 10 counties in arizona. of the 112 antibody-positive white-throated woodrats, 109 (97.3%) were c ...200415707295
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