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blood sugar lowering potentiality of selected cucurbitaceae plants of indian origin.using five experimental models, the blood sugar lowering efficacy of eight plants of cucurbitaceae family has been assessed. the ethanolic extract of cucumis sativus linn, cucumis melo utilissimum roxb, cucumis melo linn, benincasa hispida thunb cogn and tricosanthes anguina nees, when administered in 250 mg/kg dose, orally to rats failed to lower blood sugar or to depress the peak value, after glucose load. however, ethanolic extract of momordica charantia linn plant and coccinia indica whit an ...19892620957
immunopotentiator separated from hot water extract of the seed of benincasa cerifera savi (tohgashi).the separation and properties of a new immuno-potentiator, benincasa cerifera mitogen (bcm) fraction, were investigated. bcm fraction was separated from hot water extract of the seed of benincasa cerifera savi (tohgashi) by gel filtration using sepharose 4b. bcm fraction is a heteropolymer consisting of uronic acid, neutral sugars, protein, and phosphorus. the proliferation and differentiation of murine b cells were markedly stimulated by bcm fraction. the in vitro development of peritoneal macr ...19853872710
[medicinal foodstuffs. xi. histamine release inhibitors from wax gourd, the fruits of benincasa hispida cogn].the methanol extract of wax gourd (japanese name "tougan"), the fruits of benincasa hispida cogn. (cucurbitaceae), was found to show inhibitory activity on the histamine release from rat exudate cells induced by antigen-antibody reaction. through bioassay-guided separation, four known triterpenes and two known sterols were isolated as active components together with a flavonoid c-glycoside, an acylated glucose, and a benzyl glycoside. among the active triterpenes and sterols, two triterpenes, al ...19989612135
extracts of benincasa hispida prevent development of experimental ulcers.benincasa hispida (b. hispida) is recommended in ayurveda for the management of peptic ulcers. therefore, anti-ulcerogenic activity of different extracts of b. hispida (fresh juice, supernatant and residue fraction of centrifuged juice, alcoholic and petroleum ether extract) were studied in aspirin plus restraint, swimming stress, indomethacin plus histamine and serotonin-induced ulcers in rats and mice. the oral feeding of different doses of the extract significantly reduced the ulcer index pro ...200111694361
a novel subtilase from common bean leaves.we describe the isolation of a protease from common bean leaves grown in the field. on the basis of its biochemical properties it was classified as serine proteinase belonging to the subtilisin clan. isoelectric focusing resulted in a single band at ph 4.6, and sds-page in a single band corresponding to m(r) 72 kda. the proteinase activity is maximal at ph 9.9 and shows high stability in the alkaline region. the relative activities of the proteinase for eight different synthetic substrates were ...200212387886
[effect of haidonghua powder(hdhp) on hypothalamic obesity in rats].to study the effect of hdhp including laminaria japonica aresch. and benincasa hispida(thunb.) cogn. etc. on antiobesity in rats with hypothalamic obesity.200012515214
purification and characterization of alpha- and beta-benincasins, arginine/glutamate-rich peptides with translation-inhibiting activity from wax gourd seeds.two peptides, with a molecular mass of about 11 kda and an n-terminal sequence abundant in arginine and glutamine residues, were isolated from wax gourd seeds. the isolation protocol included affinity chromatography on affi-gel blue gel, ion-exchange chromatography on mono-s and gel filtration on superdex 75. the peptides, designated alpha- and beta-benincasins, inhibited cell-free translation in a rabbit reticulocyte lysate system with an ic(50) of 20 and 320 pm, respectively. alpha-benincasin ...200312576080
arsenic and heavy metal contamination of vegetables grown in samta village, bangladesh.drinking of arsenic (as) contaminated well water has become a serious threat to the health of many millions in bangladesh. however, the implications of contamination of agricultural soils from long-term irrigation with as-contaminated groundwater for phyto-accumulation in food crops, and thence dietary exposure to as, and other metals, has not been assessed previously in bangladesh. various vegetables were sampled in samta village in the jessore district of bangladesh, and screened for as, cd, p ...200312738203
antioxidant activities of various fruits and vegetables produced in taiwan.fruits and vegetables have been known to contain a variety of antioxidant components. it has been suggested that antioxidants may protect biomolecules from oxidative damage and therefore be associated with reduced risks of cardiovascular disease and certain cancer. the antioxidant abilities of various parts of eight common fruits and vegetables produced in taiwan were investigated, including tomato, guava, squash, tangerine, wax gourd, pineapple, chayote, and eggplant. squash, wax gourd, tomato, ...200415545051
[cloning, expression of the cp gene and antiserum preparation of zucchini yellow mosaic virus infecting benincasa hispida cogn. var. chieh-qua how].a guangzhou isolate of zymv infecting benincasa hispida cogn. var. chieh-qua how was identified by indicator tests and partial sequence amplification. the coat protein (cp) gene of this virus was amplified by rt-pcr, and ligated to the expression vector pet-22b(+). the recombinant plasmid pet-zcp was transformed into e. coli bl21 (de3) and then induced to express by iptg. it was shown that the cp gene was highly expressed by sds-page and western blot analysis. the molecular weight of the recombi ...200515847180
di-2-ethylhexyl phthalate in the fruits of benincasa hispida.di-2-ethylhexyl phthalate (dehp) is a commonly used plasticizer that is harmful to human health. magnetic resonance spectroscopy from the edible fruit flesh of benincasa hispida (wax gourd) of the plant family curcurbitaceae. the dehp content of seven wax gourd samples collected from southern and northern provinces in china was determined as (mean +/- sd): 18.3 +/- 0.43, 2.64 +/- 0.44, 44.0 +/- 0.34, 62.5 +/- 0.48, 52.0 +/- 0.42, 58.3 +/- 0.55 and 75.5 +/- 0.63 mg kg-1 fresh weight, respectively ...200616766454
completion of the genome sequence of watermelon silver mottle virus and utilization of degenerate primers for detecting tospoviruses in five serogroups.abstract the nucleotide sequence of the l rna of watermelon silver mottle virus (wsmov) was determined. combined with the previous work on m and s rnas, the whole genomic sequence of this member of the genus tospovirus was completed. the l rna is 8,917 nucleotides in length, with one large open reading frame encoding a translation product of 2,878 amino acids (331.8 kda) on the viral complementary strand. the l protein shares amino acid identities of only 44.3 and 46.5% with tomato spotted wilt ...200118943848
effect of benincasa hispida cogniaux on high glucose-induced vascular inflammation of human umbilical vein endothelial cells.vascular inflammation is an important factor which can promote diabetic complications. preliminary investigations of several crude plant extracts including aqueous extract of benincasa hispida cogniaux exhibit anti-inflammatory properties. this study investigates the mechanism of anti-vascular inflammatory activity of an aqueous extract of b. hispida cogniaux (abh) in human umbilical vein endothelial cells (huvecs). the study was performed on huvecs that were pretreated with various concentratio ...200919063994
effect of extract of benincasa hispida on oxidative stress in rats with indomethacin induced gastric ulcers.this study was undertaken to determine the healing of ulcers induced by indomethacin due to antioxidant role of fruit extract of benincasa hispida (ashgourd) on ulcers in rats. malondialdehyde (mda) in rbc and antral homogenate was determined to measure tissue oxidation. superoxide dismutase (sod) in rbc and antral homogenate, plasma and homogenate vitamin c were estimated as measures of antioxidant defense. on induction of gastric ulcer, there was significant increase in sod in rbc and homogena ...200819130862
renoprotective activity of benincasa cerifera fruit extract on ischemia/reperfusion-induced renal damage in rat.evidence suggests that reactive oxygen species play a role in the pathophysiology of renal ischemia/reperfusion (i/r) injury. this study was designed to investigate the renoprotective activity of methanolic fruit extract of benincasa cerifera in i/r-induced kidney failure in rats.200919395782
antinociceptive and anti-pyretic activity of benincasa hispida (thunb.) cogn. in wistar albino rats.the seeds of benincasa hispida (thunb) cogn. (family: cucurbitaceae) was extracted with ethanol and was used to study acute toxicity, antinociceptive and anti-pyretic effects. brewer's yeast (15%) was used to induce pyrexia in rats. the extract was non lethal to the rats up to the dose of 5000 mg/kg b.w. at doses of 250 and 500 mg/kg b.w, the extract significantly (p<0.05) increased the antinociceptive effective in a dose dependent manner in rats. similarly, at doses of 250 and 500 mg/kg b.w the ...200919553176
isolation and characterization of lactic acid bacteria from yan-dong-gua (fermented wax gourd), a traditional fermented food in taiwan.yan-dong-gua (fermented wax gourd; a traditional fermented food in taiwan) samples were collected at five time intervals from a fixed fermenting bucket. eighty-five cultures of lactic acid bacteria (lab) were isolated from yan-dong-gua samples, and the isolates were divided into classes by phenotype and then groups by restriction fragment length polymorphism analysis and sequencing of 16s ribosomal dna. phenotypic and biochemical characteristics identified two bacterial groups (a and b) and show ...200919914580
evaluation of anti-compulsive effect of methanolic extract of benincasa hispida cogn. fruit in mice. 201020635538
gastroprotective effect of benincasa hispida fruit extract.the antiulcer activity of benincasa hispida (thunb.) cogn. fruit was evaluated in rats against ethanol-induced gastric mucosal damage, pylorus ligated (pl) gastric ulcers, and cold restraint-stress (crs)-induced gastric ulcer models.200821279184
immunohistochemical analysis of cell wall hydroxyproline-rich glycoproteins in the roots of resistant and susceptible wax gourd cultivars in response to fusarium oxysporum f. sp. benincasae infection and fusaric acid treatment.hydroxyproline-rich glycoproteins (hrgps) play a defensive role in host-pathogen interactions. however, specific roles of individual hrgps in plant defense against pathogen are poorly understood. changes in extracellular distribution and abundance of individual cell wall hrgps were investigated on root sections of two wax gourd (benincasa hispida cogn.) cultivars (fusarium wilt resistant and susceptible, respectively), which were analyzed by immunolabelling with 20 monoclonal antibodies recogniz ...201121505833
evaluation of antidiabetic and related actions of some indian medicinal plants in diabetic rats.to evaluate antidiabetic activity of chloroform extracts of acacia arabica bark, benincasa hispida fruit, tinispora cordifolia stem, ocimum sanctum areal parts and jatropha curcus leaves.201121771409
Formulation and in vitro evaluation of the topical antiageing preparation of the fruit of Benincasa hispida.Ageing is the phase of gradual decline of body efficiency and metabolic activities after reaching a maturity stage. Free radicals cause oxidative alterations in collagen, elastin material and changes in membrane characteristics and induce polymerization reactions. Use of topical antioxidants can overcome some of these effects and retard actinic ageing. Herbal products are popular due to their minimum risk of side-effects with maximum efficacy. The present study was undertaken to evaluate the ant ...201122022154
Influence of antioxidant rich fresh vegetable juices on starch induced postprandial hyperglycemia in rats.This research analyzed the major chemical components and multiple antioxidant activities present in the fresh juice of eight vegetables, and studied their influence on starch induced postprandial glycemia in rats. A SDS-PAGE based protein fingerprint of each vegetable juice was also prepared. The yields of juice, chemical components like total proteins, total polyphenols, total flavonoids, total anthocyanins and free radicals like the ABTS?(+) cation, DPPH, H(2)O(2), scavenging activities and re ...201121874188
nitric oxide-dependent hypotensive effects of wax gourd juice.the wax gourd (benincasa hispida (thunb) cong.) is a long-season vegetable that has been used in traditional chinese medicine to treat high blood pressure. however, precise details of its effect and the mechanism of action involved are still lacking.201121963558
[Field resistance of Phytophthora melonis to metalaxyl in South China].Phytophthora melonis is the casual agent of wax gourd and cucumber Phytophthora blight which becomes a constraint for sustainable production of the related crops. Metalaxyl is one of the principal fungicides for controlling the disease now. The objectives of the present study were: (1) to investigate the baseline sensitivity and field resistance of P. melonis to metalaxyl in South China; (2) to test the occurrence of metalaxyl-resistant mutants from metalaxyl-sensitive wild type strains exposed ...201122097773
antimicrobial studies on methanol extract of benincasa hispida cogn., fruit.the methanol extract of wax gourd, the fruits of benincasa hispida cogn.(cucurbitaceae) was found to show no inhibition against three gram positive bacteria staphylococcus aureus, staphylococcus epidermidis, and bacillus subtilis and three gram negative bacteria escherichia coli, pseudomonas aeruginosa and klebsiella pneumonia by cup-plate method whereas antifungal studies showed significant inhibition against candida albicans in the concentration of 30 mg/ml and there was no inhibition against ...200322557093
bio-protective potential of lactic acid bacteria isolated from fermented wax gourd.the antifungal activities of 85 lactic acid bacteria strains isolated from fermented wax gourd against the four fungal species, penicillium oxalicum, aspergillus flavus, aspergillus sydowii, and mucor racemosus, were determined. inhibitory activity against at least one or more fungal species was observed with 27 weissella cibaria and 11 weissella paramesenteroides strains. among these strains, w. cibaria 861006 and w. paramesenteroides 860509 showed greater inhibitory activities and were therefo ...201222307833
purification, cdna cloning and recombinant protein expression of a phloem lectin-like anti-insect defense protein bplp from the phloem exudate of the wax gourd, benincasa hispida.latex and other exudates in plants contain various proteins that are thought to play important defensive roles against herbivorous insects and pathogens. herein, the defensive effects of phloem exudates against the eri silkworm, samia ricini (saturniidae, lepidoptera) in several cucurbitaceous plants were investigated. it was found that phloem exudates are responsible for the defensive activities of cucurbitaceous plants, such as the wax gourd benincasa hispida and cucumis melo, especially in b. ...201323453909
shelf-life and microbiological safety studies of refrigerated petha sweet.this study was conducted at indian institute of vegetable research, varanasi (i.i.v.r.), uttar pradesh from 2006 to 2009 for evaluating comparative physico-chemical, microbiological and sensory attributes of crystallized and kashi petha at refrigerated storage (4 ± 1 °c) condition up to 90 days. the petha were manufactured using 2 varieties of ash gourd developed at i.i.v.r. i.e.; kashi dhawal and kashi ujwal, selected based on different parameters suitable for petha sweet preparation. the used ...201426396345
molecular evidence for occurrence of tomato leaf curl new delhi virus in ash gourd (benincasa hispida) germplasm showing a severe yellow stunt disease in india.an evaluation of 70 accessions of ash gourd germplasm grown at national bureau of plant genetic resources, new delhi, india during kharif season (2010) showed natural occurrence of a yellow stunt disease in three accessions (ic554690, ic036330 and pusa ujjwal). a set of begomovirus specific primers used in pcr gave expected amplicon from all the symptomatic plants; however no betasatellite was detected. complete genome of the begomovirus (dna-a and dna-b), amplified through rolling circle amplif ...201324426262
evaluation of polyherbal formulation (sjt-ht-03) for antihypertensive activity in albino rats.hypertension is an incurable pathological condition and lifelong therapy is required. long term use of conventional synthetic anti-hypertensive drugs is associated with a spectrum of toxic effects. however, therapeutic interventions using herbal drugs for hypertension have gained considerable attention worldwide.201726195912
traditional chinese medicine, food therapy, and hypertension control: a narrative review of chinese literature.despite the lack of english literature about traditional chinese medicine (tcm) food therapy, there is abundant chinese literature about the application of food therapy for hypertension control. this paper summarizes basic concepts of tcm, the principles of food therapy and its application for hypertension control according to chinese literature. in tcm, food is conceptualized according to both nutritional and functional aspects, and can be used to treat illnesses. four principles of tcm food th ...201627852126
revisiting "vegetables" to combat modern epidemic of imbalanced glucose homeostasis.vegetables have been part of human food since prehistoric times and are considered nutritionally necessary and good for health. vegetables are rich natural resource of biological antioxidants and possess capabilities of maintaining glucose homeostasis. when taken before starch-rich diet, juice also of vegetables such as ridge gourd, bottle gourd, ash gourd, chayote and juice of leaves of vegetables such as radish, indian dill, ajwain, tropical green amaranth, and bladder dock are reported to arr ...201424991093
genotyping-by-sequencing of a melon (cucumis melo l.) germplasm collection from a secondary center of diversity highlights patterns of genetic variation and genomic features of different gene pools.melon (cucumis melo l.) is one of the most important horticultural species, which includes several taxonomic groups. with the advent of next-generation sequencing, single nucleotide polymorphism (snp) markers are widely used in the study of genetic diversity and genomics.201728068911
elucidation of flavonoids from carissa congesta, polyalthia longifolia, and benincasa hispida plant extracts by hyphenated technique of liquid chromatography-mass spectroscopy.carissa congesta (cc), polyalthia longifolia (pl), and benincasa hispida (bh) are economically important plants.201727695269
prediction of the antiglycation activity of polysaccharides from benincasa hispida using a response surface methodology.benincasa hispida is a popular vegetable in china. our previous experiments suggested that polysaccharides isolated from b. hispida fruits (pbh) have antiglycation effect and dpph free radical scavenging activity. ultrasonic treatments can be used to extract polysaccharides from benincasa hispida (pbh). the aim of this study was to investigate the correlation between the ultrasonic treatment conditions and the antiglycation activity of pbh. a mathematical model was generated with an artificial n ...201627474577
bio-inspired sustainable and green synthesis of plasmonic ag/agcl nanoparticles for enhanced degradation of organic compound from aqueous phase.in the current study, we report the utilization of the biogenic potential of benincasa hispida (ash gourd) peel extract for the synthesis of ag embedded agcl nanoparticles nanoparticles (ag/agcl nps) without the use of any external organic solvents. the appearance of dark brown color from the pale yellow color confirmed the formation of ag/agcl nanoparticles which was further validated by absorbance peak using uv-visible spectroscopy. the phytochemicals (flavones) present in the b. hispida peel ...201627246560
effects of thermal processing and pulp filtration on physical, chemical and sensory properties of winter melon juice.winter melon (benincasa hispida) is a widely consumed crop in asia, and believed to impart special benefits to human health. the nutritional composition and sensory properties of four juice types, resulting from a combination of pulp levels (low/high pulp, lp/hp) and thermal processing (with/without boiling, b/nb), lpnb, hpnb, lpb and hpb, were compared.201727099203
quantification of quercetin and rutin from benincasa hispida seeds and carissa congesta roots by high-performance thin layer chromatography and high-performance liquid chromatography.in indian ayurvedic system, benincasa hispida (bh) and carissa congesta (cc) are well-known plants used for major and minor ailments. bh has been regarded as kushmanda, whereas cc has been used in immune-related disorders of the human system. quercetin and rutin identified from the vast plethora of plant extracts have proved to possess ethnopharmacological relevance.201726941534
two chitotriose-specific lectins show anti-angiogenesis, induces caspase-9-mediated apoptosis and early arrest of pancreatic tumor cell cycle.the antiproliferative activity of two chito-specific agglutinins purified from benincasa hispida (bhl) and datura innoxia (dil9) of different plant family origin was investigated on various cancer cell lines. both lectins showed chitotriose specificity, by inhibiting lectin hemagglutinating activity. on further studies, it was revealed that these agglutinins caused remarkable concentration-dependent antiproliferative effect on human pancreatic cancerous cells but not on the normal human umbilica ...201626795117
high-density genetic map construction and gene mapping of pericarp color in wax gourd using specific-locus amplified fragment (slaf) sequencing.high-density map is a valuable tool for genetic and genomic analysis. although wax gourd is a widely distributed vegetable of cucurbitaceae and has important medicinal and health value, no genetic map has been constructed because of the lack of efficient markers. specific-locus amplified fragment sequencing (slaf-seq) is a newly developed high-throughput strategy for large-scale single nucleotide polymorphism (snp) discovery and genotyping.201526647294
anti-aging potential of phytoextract loaded-pharmaceutical creams for human skin cell longetivity.the exposure to ultraviolet radiations (uvr) is the key source of skin sunburn; it may produce harmful entities, reactive oxygen species (ros), leading to aging. the skin can be treated and protected from the injurious effects of ros by using various pharmaceutical formulations, such as cream. cream can be loaded with antioxidants to quench ros leading to photo-protective effects. moreover, modern medicines depend on ethnobotanicals for protection or treatment of human diseases. this review arti ...201526448818
tempo-mediated oxidized winter melon-based carbonaceous aerogel as an ultralight 3d support for enhanced photodegradation of organic pollutants.natural biomass based carbonaceous aerogels are becoming promising lightweight, biodegradable matrices to supersede traditional support materials in realizing future sustainable photochemistry and environmental protection. herein, flower-like biobr loaded onto an ultralight tempo-mediated oxidized carbonaceous aerogel (bob@owmca) support was successfully prepared using the edible winter melon as source material via a simple solvothermal method. the three-dimensional sponge-like owmca with surfac ...201526344492
structural elucidation of chemical constituents from benincasa hispida seeds and carissa congesta roots by gas chromatography: mass spectroscopy.benincasa hispida (bh) and carissa congesta (cc) are regarded as ethnopharmacological imperative plants in asian countries.201726130941
the relationship between working conditions and adverse health symptoms of employee in solar greenhouse.to determine the correlation between the working environment and the health status of employees in solar greenhouse, 1171 employees were surveyed. the results show the 'greenhouse diseases' are affected by many factors. among general uncomforts, the morbidity of the bone and joint damage is the highest and closely related to labor time and age. planting summer squash and wax gourd more easily cause skin pruritus. asthma-related cough, eye disease, and skin pruritus are significantly correlated w ...201525716566
characterization and chromosomal organization of ty1-copia retrotransposons in wax gourd.wax gourd (2n=2x=24) is an important vegetable species in cucurbitaceae. because it can be stored for a very long period of time, it plays an important role in ensuring the annual supply and regulating off-season supply of the vegetables. however, the availability of genetic information about wax gourd is limited. this study aimed to identify the useful genetic information for wax gourd. the conserved domains of reverse transcriptase (rt) genes of ty1-copia retrotransposons were isolated from th ...201425108132
management of experimental hypochlorhydria with iron deficiency by the composite extract of fumaria vaillantii l. and benincasa hispida t. in rat.the aim of the present study was to search the effective ratio of whole plant of fumaria vaillantii loisel (fumaria vaillantii l.) and fruit of benincasa hispida thunb. (benincasa hispida t.) in composite form, namely "fvbh" for the management of hypochlorhydria along with iron deficiency in male albino rats. hypochlorhydria refers to suppression of hydrochloric acid secretion by the stomach. hypochlorhydria was induced by ranitidine in this study. we used four composite extracts of the mentione ...201425097423
marker based standardization of polyherbal formulation (sjt-di-02) by high performance thin layer chromatography method.preparation of highly standardized herbal products with respect to chemical composition and biological activity is considered to be a valuable approach in this field. sjt-di-02 polyherbal formulation was successfully developed at our institute and filed for patent at mumbai patent office.201425035642
cationic bioactive peptide from the seeds of benincasa hispida.a designated bioactive peptide "hispidalin" purified from the seeds of benincasa hispida, which is a medicinal plant, belongs to cucurbitaceae family. purification was achieved by using a procedure consisting of extraction from potassium phosphate buffer followed by fplc and hplc steps. based on amino acid residue, this peptide is amphipathic and basic with one net positive charge having isoelectric ph 8.1. this peptide is without sulphur containing amino acid suggesting its extended conformatio ...201424834076
process optimization for the manufacture of angoori petha.angoori petha (ap) is delicacy which is relished by large section of indian population. fully ripened ash gourd fruits were osmotically dehydrated at different lime water concentration, lime water treatment time and sugar concentration for the manufacture of ap. the response variables consisted of sensory parameter for flavour, body and texture, colour and appearance and overall acceptability and physico-chemical properties. a central composite rotatable design (ccrd) was used as experimental de ...201424803695
heavy metals bioconcentration from soil to vegetables and assessment of health risk caused by their ingestion.the present study was undertaken to assess the non-carcinogenic human health risk of heavy metals through the ingestion of locally grown and commonly used vegetables viz. raphanus sativus (root vegetable), daucus carota (root vegetable), benincasa hispida (fruit vegetable) and brassica campestris leaves (leafy vegetable) in a semi-urbanized area of haryana state, india. heavy metal quantification of soil and vegetable samples was done using flame atomic absorption spectrophotometer. lead, cadmiu ...201424464601
new triterpenoids and other constituents from the fruits of benincasa hispida (thunb.) cogn.benincasa hispida (thunb.) cogn. fruits are widely consumed in china and tropical countries. this study identifies three new triterpenoids, 3α,29-o-di-trans-cinnamoyl-d:c-friedooleana-7,9(11)-diene (1), oleanolic acid 28-o-β-d-xylopyranosyl-[β-d-xylopyranosyl-(1→4)]-(1→3)-α-l-rhamnopyranosyl-(1→2)-α-l-arabinopyranoside (2), and oleanolic acid 28-o-β-d-glucopyranosyl-(1→3)-β-d-xylopyranosyl-[β-d-xylopyranosyl-(1→4)]-(1→3)-α-l-rhamnopyranosyl-(1→2)-α-l-arabinopyranoside (3), together with 12 known ...201324313299
antioxidant and α-glucosidase inhibitory activities of cucurbit fruit vegetables and identification of active and major constituents from phenolic-rich extracts of lagenaria siceraria and sechium edule.antioxidant and α-glucosidase activities and total phenolic contents (tpc) in sequential extracts of dried pulps from seven cucurbit fruit vegetables were determined for the first time. the highest tpc and metal chelating activity were obtained from the chloroform extracts of luffa acutangula (28.04 ± 0.37 mg gae/g extract) and benincasa hispida (ec50 = 0.44 ± 0.03 mg/ml), respectively. the ethyl acetate extract of sechium edule showed the highest 1,1-diphenyl-2-picrylhydrazyl (dpph) free radica ...201324059845
de novo assembly and characterization of the transcriptome, and development of ssr markers in wax gourd (benicasa hispida).wax gourd is a widely used vegetable of cucuribtaceae, and also has important medicinal and health values. however, the genomic resources of wax gourd were scarcity, and only a few nucleotide sequences could be obtained in public databases.201323951078
evaluation of 5α-reductase inhibitory activity of certain herbs useful as antiandrogens.this study demonstrates 5α-reductase inhibitory activity of certain herbs useful in the management of androgenic disorders. ganoderma lucidum (curtis) p. karst (gl), urtica dioica linn. (ud), caesalpinia bonducella fleming. (cb), tribulus terrestris linn. (tt), pedalium murex linn. (pm), sphaeranthus indicus linn. (si), cuscuta reflexa roxb. (cr), citrullus colocynthis schrad. (cc), benincasa hispida cogn. (bh), phyllanthus niruri linn. (pn) and echinops echinatus linn. (ee) were included in the ...201423710567
uptake of di(2-ethylhexyl) phthalate (dehp) by the plant benincasa hispida and its use for lowering dehp content of intercropped vegetables.uptake of di(2-ethylhexyl) phthalate (dehp) by the plant benincasa hispida and its use for topical phytoremediation were investigated by cultivation of plants in dehp-contaminated environments. the results showed that major plant organs of b. hispida , including leaves, stems, and fruits, readily absorbed dehp from the air. the amount of dehp that accumulated in leaves, stems, and fruits was mainly dependent upon exposure time, and most dehp accumulated in their inner tissues. a single plant of ...201323675826
extract of wax gourd peel prevents high-fat diet-induced hyperlipidemia in c57bl/6 mice via the inhibition of the pparγ pathway.wax gourd is a popular vegetable in east asia. in traditional chinese medicine, wax gourd peel is used to prevent and treat metabolic diseases such as hyperlipidemia, hyperglycemia, obesity, and cardiovascular disease. however, there is no experimental evidence to support these applications. here, we examined the effect of the extract of wax gourd peel (ewgp) on metabolic disorders in diet-induced c57bl/6 obese mice. in the preventive experiment, ewgp blocked body weight gain and lowered serum t ...201323533476
supercritical carbon dioxide extraction of seed oil from winter melon (benincasa hispida) and its antioxidant activity and fatty acid composition.in the present study, supercritical carbon dioxide (sc-co(2)) extraction of seed oil from winter melon (benincasa hispida) was investigated. the effects of process variables namely pressure (150-300 bar), temperature (40-50 °c) and dynamic extraction time (60-120 min) on crude extraction yield (cey) were studied through response surface methodology (rsm). the sc-co(2) extraction process was modified using ethanol (99.9%) as co-solvent. perturbation plot revealed the significant effect of all pro ...201323322066
optimization of ultrasound-assisted extraction of crude oil from winter melon (benincasa hispida) seed using response surface methodology and evaluation of its antioxidant activity, total phenolic content and fatty acid composition.in the present study, ultrasound-assisted extraction of crude oil from winter melon seeds was investigated through response surface methodology (rsm). process variables were power level (25-75%), temperature (45-55 °c) and sonication time (20-40 min). it was found that all process variables have significant (p < 0.05) effects on the response variable. a central composite design (ccd) was used to determine the optimum process conditions. optimal conditions were identified as 65% power level, 52 ° ...201223044712
effect of different solvent extracts of benincasa hispida t. on experimental hypochlorhydria in rat.hypochlorhydria is a common problem in any age of people like other gastric disorders. it has so many etiologies such as sympathetic dominance, antiseretory drug use, excess sugar and refined foods, etc. in the present study, our objective was to search out the effective solvent extract of fruit of benincasa hispida t. for the management of hypochlorhydria in model male albino rats. hypochlorhydria was induced in rat as per standard method by oral administration of ranitidine. different solvent ...201222470892
clinical evaluation of kushmanda ghrita in the management of depressive illness.depressive illness has been considered as a problematic mental illness since antiquity. the treatment modalities of depressive illness are of many kinds. use of medhya rasayana drugs is a unique method of treatment described in ayurveda for depressive illness. kushmanda (benincasa hispida) is one of the medhya rasayana as described by bhava mishra. ghrita is also considered as medhya rasayana by almost all acharyas. keeping this background kushmanda ghrita has been selected as a trial drug to tr ...201122408308
antidepressant-like activity of benincasa hispida fruits in mice: possible involvement of monoaminergic and gabaergic systems. 201222368421
preparation of polysaccharides from wax gourd.preparation of polysaccharides from the wax gourd was studied. the crude polysaccharides were extracted by ethanol precipitation, and deproteinized by the hydrochloric acid method. the deproteinized polysaccharides were separated by column chromatography to obtain the pure polysaccharides. the pure polysaccharides have a β-d-pyranosidic bond, and their molecular weight distribution is about 22,500. it was indicated that the final product had much more purity by ir spectrum analysis, uv absorptio ...201121355748
taxonomic significance of trichomes micromorphology in cucurbits.studies on trichomes micromorphology using scanning electron microscope (sem) were undertaken in 23 species with one variety under 13 genera of the family cucurbitaceae (viz., benincasa hispida (thunb.) cogn., citrullus lanatus (thunb.) matsum. & nakai, cucumis melo var. agrestis naudin, cucumis sativus l., diplocyclos palmatus (l.) c. jeffrey, edgaria dargeelingensis c.b. clarke, gynostemma burmanicum king ex chakr., gynostemma pentaphyllum (thunb.) makino, gynostemma pubescens (gagnep.) c.y. w ...201123961108
effect of benincasa hispida fruits on testosterone-induced prostatic hypertrophy in albino rats.benincasa hispida cogn. has been used traditionally in india for the management of urinary disorders. the fruit of b hispida is used as a diuretic and the seeds have been reported to possess antiangiogenic effects in prostate cells.201024688153
effect of particle size reduction on physicochemical properties of ashgourd (benincasa hispida) and radish (raphanus sativus) fibres.the present work was aimed at studying the effect of particle size reduction on the physicochemical properties of ashgourd and radish fibre. both the fibres after extraction of juice were dehydrated and subjected to granulometry to obtain 30, 60 and 100 mesh particles. the yield was more for 60 mesh particles. the image analysis as well as microstructural analysis of particles by scanning electron microscopy showed distinctive properties. the 30 mesh particles of ashgourd and radish fibre contai ...201019961356
structural characterization of dietary fiber of green chalcumra (benincasa hispida) fruit by nmr spectroscopic analysis.a water-soluble dietary fiber was isolated from the hot aqueous extract of chalcumra (benincasa hispida) fruit. the polysaccharide was found to contain d-galactose and d-methyl galacturonate in a molar ratio of 2:1. on the basis of acid hydrolysis, methylation analysis, periodate oxidation, and nmr spectroscopic studies (1h, 13c, tocsy, dqf-cosy, noesy, roesy, hmqc, and hmbc), the repeating unit of the polysaccharide was established as -->4)-beta-d-galp-(1-->4)-beta-d-galp-(1-->2)-alpha-d-galpa6 ...200919476003
[comparative analysis of rdna distribution in metaphase chromosomes of cucurbitaceae species].fluorescence in situ hybridization (fish) and double fish experiments were carried out to ascertain the chromosomal distribution patterns of the 45s and 5s ribosomal dnas in the three species of cucurbitaceae. five pairs of 45s rdna loci and two pairs of 5s rdna signals were detected on chromosomes of cucurbita moschata duch. luffa cylindrical roem. contained five pairs of 45s rdna loci and one pair of 5s rdna loci. in benincasa hispida cogn., two pairs of 45s rdna sites and one pair of 5s rdna ...200717548333
serine proteinase inhibitor from wax gourd (benincasa hispida [thunb] cogn.) seeds.two squash family protease inhibitors were obtained from wax gourd (benicasa hispida [thunb] cogn.). even though they were distinctly separated by reversed-phase chromatography, the amino acid sequences of two inhibitors were identical. both inhibitors were converted into each other, perhaps due to cis-trans isomerization of characteristic pro in the c-terminal region.200616556998
anti-angiogenic effect of the seed extract of benincasa hispida cogniaux.benincasa hispida in korea was used mainly diabetes and diuresis diseases. this study was carried out to evaluate anti-angiogenic effect of the seed extract of benincasa hispida cogniaux. basic fibroblast growth factor (bfgf) is a potent angiogenic factor found in various tumors. in this study, we found that the seed extract of benincasa hispida cogniaux decreased bfgf-induced endothelial cell proliferation and tube formation in a dose-dependent manner. besides, benincasa hispida seed extract sh ...200515740888
antioxidant and angiotension-converting enzyme inhibition capacities of various parts of benincasa hispida (wax gourd).vegetables and fruits have been shown to be good sources of antioxidants. benincasa hispida (wax gourd) has been used in traditional chinese medicine to treat hypertension and inflammation. the aims of this study were to investigate the abilities of antioxidation and inhibition of angiotensin-converting enzyme (ace) activity of wax gourd pulp, core, seed, and peel prepared by different extraction methods. the fresh weights required to reach 50% inhibition of linoleic acid oxidation were higher i ...200415285118
cell wall polysaccharides from chalkumra (benincasa hispida) fruit. part i. isolation and characterization of pectins.pectic polysaccharides were obtained from chalkumra (benincasa hispida) fruit by sequential extraction with ammonium oxalate (fraction box), dilute acid (fraction bhcl), and cold dilute alkali (fraction boh). the highest yield of polysaccharides was obtained with oxalate and hcl. box was enriched in partly methyl-esterified galacturonic acid, whereas bhcl and boh contained mostly galactose. all of the extracts showed similar elution patterns in size exclusion chromatography although the intrinsi ...200415161230
nitrate and nitrite in vegetables from north china: content and intake.the contents of nitrate and nitrite in potato, cabbage, chinese cabbage, scallion (shallot), celery, cucumber, tomato, eggplant and wax gourd taken from the north china market from 1998 to 1999 were determined. these vegetables provide the major contribution to the nitrate intake from the diet. the highest content of nitrate was found in celery followed by chinese cabbage, cabbage, scallion, wax gourd and eggplant. for all the products, a great variation in the content of nitrate was found. gene ...200212623672
[vegetables rich in carotenoids on the vitamin a status of children].vitamin a (va) deficiency is still an important nutritional problem in our country. in order to determine whether plant carotenoids ingestion can improve va nutrition, a study by using yellow and dark green vegetables was conducted in two classes of a kindergarten for ten weeks in september through december in 1996. the va nutritional status was marginal to adequate among 41 children (5.3-6.6 year-old), and serum retinols in 39% of these children were below 0.30 mg/l. each child in class a was p ...199911938982
[a cohort study on the relationship between vegetable intake and risks of lung cancer in the tin corporation (ytc) miners in yunnan].to understand the relationship between vegetable intake and risk of lung cancer in the tin corporation (ytc) miners in yunnan.200011860786
purification, characterization, and molecular cloning of a chitinase from the seeds of benincasa hispida.a chitinase was purified from the seeds of benincasa hispida, a medicinal plant also called white gourd, and a member of the cucurbitaceae family. purification was done by using a procedure consisting of only two fractionation steps: an acid denaturation step followed by ion-exchange chromatography. the sequence of the n-terminal forty amino acid residues was analyzed and the sequence indicated that the enzyme is a class iii chitinase. the enzyme, which is a basic chitinase, is one of at least f ...200111330660
purification of an osmotin-like protein from the seeds of benincasa hispida and cloning of the gene encoding this protein.a pathogenesis-related (pr) protein was purified from the seeds of benincasa hispida, which is a medicinal plant and a member of the cucurbitaceae family. purification was achieved by using a procedure consisting of an acid treatment step followed by two chromatography steps. the protein is a basic protein with molecular mass of approximately 28 kda. the sequences of the n-terminal 30 amino acids and four peptides generated from protease digestion were determined. these sequences indicated that ...200111297778
preliminary study of fresh juice of benincasa hispida on morphine addiction in mice.the juice of benincasa hispida (bh) showed significant activity against symptoms of morphine withdrawal, such as jumping response and diarrhoea, in mice. these results seem to indicate that bh may prevent the development of morphine addiction and also suppress symptoms of opioid withdrawal in animals.200011077182
cucumisin like protease from the sarcocarp of benincasa hispida var. ryukyu.a protease has been purified from the sarcocarp of benincasa hispida (thunb.) cogn. var. ryukyu by two steps of chromatography. its m(r) was estimated by sds-page to be about 67,000. the enzyme was strongly inhibited by diisopropyl fluorophosphate, but not by edta and cysteine protease inhibitors. the substrate having alanine at the position of p1 was the best among the ala-ala-pro-x-pnas (x = ala, lys, phe, glu, and diaminopropionic acid (dap)). the n-terminal sequence of the first 33 residues ...19989887522
larvicidal efficacy of some cucurbitacious plant leaf extracts against culex quinquefasciatus (say).larvicidal efficacies of extracts of five species of cucurbitacious plants, momordica charantia, trichosanthes anguina, luffa acutangula, benincasa cerifera and citrullus vulgaris were tested against the late third larval age group of culex quinquefasciatus. the larval mortality was observed after 24 h exposure. the lc50 values of m. charantia, t. anguina, l. acutangula, b. cerifera and c. vulgaris were 465.85, 567.81, 839.81, 1189.30 and 1636.04 ppm respectively.200415207304
survey, symptomatology, transmission, host range and characterization of begomovirus associated with yellow mosaic disease of ridge gourd in southern india.ridge gourd is an important vegetable crop and is affected by several biotic and abiotic factors. among the different biotic factors, ridge gourd yellow mosaic disease (rgymd) is new emerging threat for the production of ridge gourd. the incidence of the rgymd varied from 30 to 100% in southern india with highest disease incidence of 100% observed in belagavi district of karnataka state. the infected plants showed chlorosis, mosaic, cupping of leaves, blistering, reduction in leaf size and stunt ...201728770240
immediate effect of bitter gourd, ash gourd, knol-khol juices on blood sugar levels of patients with type 2 diabetes mellitus: a pilot study.the aim of this study was to investigate the immediate effect of bitter gourd, knol-khol, and ash gourd juices on blood glucose level among type ii diabetes mellitus patients.201729034203
a deletion of the gene encoding amino aldehyde dehydrogenase enhances the "pandan-like" aroma of winter melon (benincasa hispida) and is a functional marker for the development of the aroma.the gene conferring a "pandan-like" aroma of winter melon was identified. the sequence variation (804-bp deletion) found in the gene was used as the target for functional marker development. winter melon (benincasa hispida), a member of the cucurbitaceae family, is a commonly consumed vegetable in asian countries that is popular for its nutritional and medicinal value. a "pandan-like" aroma, which is economically important in crops including rice and soybean, is rarely found in most commercial v ...201728887587
cloning and characterization of wrky gene homologs in chieh-qua (benincasa hispida cogn. var. chieh-qua how) and their expression in response to fusaric acid treatment.the wrky transcription factors play an important role in plant resistance for biotic and abiotic stresses. in the present study, we cloned 10 wrky gene homologs (cqwrky) in chieh-qua (benincasa hispida cogn. var. chieh-qua) using the rapid-amplification of cdna ends (race) or homology-based cloning methods. we characterized the structure of these cqwrky genes. phylogenetic analysis of these sequences with cucumber homologs suggested possible structural conservation of these genes among cucurbit ...201728501986
therapeutic potential of benincasa cerifera: a review.benincasa cerifera (savi.), belonging to cucurbitaceae, is an annual creepy wine that posses highm edicinal value and istraditionally used as fruit and medicine throughout india. in indian system of medicine, its fruit is used as nutritive, tonic, diuretic, aphrodisiac, styptic, vermifuge and in various diseases and disorders like asthma, bronchitis, insanity, epilepsy, dry cough, fever, urethrorrhea, syphilis, hyperdipsia and vitiated conditions of pitta, etc. phytochemically the plant is found ...201627465423
preparation of a co-doped hierarchically porous carbon from co/zn-zif: an efficient adsorbent for the extraction of trizine herbicides from environment water and white gourd samples.a co-doped hierarchically porous carbon (co/hpc) was synthesized through a facile carbonization process by using co/zif-8 as the precursor. the textures of the co/hpc were investigated by scanning electron microscopy, transmission electron microscopy, x-ray diffraction, vibration sample magnetometry and nitrogen adsorption-desorption isotherms. the results showed that the co/hpc is in good polyhedral shape with uniform size, sufficient magnetism, high surface area as well as hierarchical pores ( ...201626992527
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