| [antimutagenic activities of hexane extracts of the fruit extract and the kernels of prunus mume sieb. et zucc]. | antimutagenic activities of hexane extracts obtained from the fruit extract (ue) and the kernels (ke) of p. mume were examined. these extracts showed inhibitory activities to known mutagens, 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide, benzo[alpha]pyrene and aflatoxin b1 in the ames assay using salmonella typhimurium ta100 and ta98 strains. the ue and ke fractions were then separated by silicic acid column chromatography with a stepwise elution method using ether-hexane. the location of the active ... | 1992 | 1432606 |
| [cultivation and production technics of the dark plum (prunus mume)]. | | 1985 | 2938794 |
| structural investigation on the effects of the herbs on clonorchis sinensis in rabbits. | the effects of boiled water extracts of clonorchicidal raw drugs screened by the epg counts in vivo on the structure of clonorchis sinensis were investigated. the extracts of cassia obutusifolia and dictamnus dasycarpus did not seem to induce the morphological changes of the worms, and in those of machilus thunbergii and prunús mume, widening of bladder to lower level of seminal receptacle was visible without any other changes. those of inula helenium and saussurea lappa, however, disclosed regr ... | 1985 | 3895883 |
| alternations of clonorchis sinensis epg by administration of herbs in rabbits. | in order to investigate clonorchicidal activity in vivo, boiled water extracts of 32 species of clonorchicidal raw drugs in vitro were orally administered into rabbits infected with clonorchis sinensis. the results of the observation of epg variation were as follows: suppression effects of egg-laying capacity from the rabbits administered prunus mume and inula helenium were greatest. those from dictamnus dasycarpus and saussurea lappa were somewhat effective. machilus thunbergii and cassia obutu ... | 1985 | 4025216 |
| microchemical investigation of medicinal plants. i. the antitubercular principle in prunus mume and schizandra chinensis. | | 1968 | 4978259 |
| screening of the wormicidal chinese raw drugs on clonorchis sinensis. | the wormicidal effect on clonorchis sinensis in boiled water extracts of 223 species (vegetable origin 206, animal origin 10, mineral origin 7) of raw drugs prescribed in oriental medicine was observed in vitro. the wormicidal substances were detected from 31 of the above-mentioned species. the wormicidal substances extracted from platycodon grandiflorum (radix), schizandra chinensis (fruit), polygala tenuifolia (herb) and aster tataricus (radix) were most effective. those from smilax glabra (ra ... | 1981 | 6764091 |
| immunochemical characterization of alkaline-soluble polysaccharide, p-1, from the kernels of prunus mume sieb. et zucc. | polyclonal antibodies against p-1, a pectic polysaccharide fraction extracted with 0.5 m naoh from the kernels of prunus mume and consisted of arabino-galacturonan, and i-3, the partial acid (0.1 m trifluoroacetic acid) hydrolysate of p-1, were prepared in japanese white rabbits. competitive elisa experiments strongly suggested that anti p-1 and anti i-3 antibodies were different but p-1 and i-3 cross-reacted with each other to recognize a partly similar epitope structure. the reactivities of po ... | 1996 | 8782409 |
| architecture of alkaline-soluble and bioactive polysaccharide from the kernels of prunus mume sieb. et zucc. assessed by anti p-1 antibody. | p-1 was partially hydrolyzed with 0.01, 0.05, and 0.1 m trifluoroacetic acid (tfa), successively, and the dialyzable (e-1, e-2, and e-3) and non-dialyzable (i-1, i-2, and i-3) fractions were prepared and analyzed chemically and immunochemically. either i-1 or e-1 reacted with anti p-1 serum as strongly as p-1 and were mitogenic. the cross-reactivity of i-2 and i-3 was less than i-1 with anti p-1 serum. however, they were as mitogenic as i-1. the cross-reactivity of e-2 and e-3 to anti p-1 serum ... | 1996 | 8987860 |
| mumefural, citric acid derivative improving blood fluidity from fruit-juice concentrate of japanese apricot (prunus mume sieb. et zucc). | the effects of food components on blood fluidity were studied by in vitro assay using a dedicated microchannel instrument for model capillaries. we found that the fruit-juice concentrate of the japanese apricot (prunus mume sieb. et zucc), a traditional japanese food, markedly improved the fluidity of human blood. using hplc, we isolated the active compounds and characterized them using uv, ms, ir, and nmr. they included a novel compound, 1-[5-(2-formylfuryl)methyl] dihydrogen 2-hydroxypropane-1 ... | 1999 | 10552374 |
| [anti-helicobacter pylori effects of bainiku-ekisu (concentrate of japanese apricot juice)]. | helicobacter pylori (h.p.) bacteria are the major causes of gastro-duodenal disease, and some association with stomach cancer has been suggested. recently, h.p. eradicating treatment has been practiced using antibiotics and proton-pump inhibitors. however, at the same time, some reports have been made on the side-effects of this treatment; allergic reactions and uneffective resistant bacteria. under these circumstances, there is a strong need for medicines, which are less harmful to the body, ca ... | 2002 | 11979735 |
| new flavonol oligoglycosides and polyacylated sucroses with inhibitory effects on aldose reductase and platelet aggregation from the flowers of prunus mume. | the methanolic extract from the fresh flowers of prunus mume exhibited inhibitory effects against aldose reductase and platelet aggregation. from the methanolic extract, two new flavonol oligoglycosides, 2' '-o-acetylrutin and 2' '-o-acetyl-3'-o-methylrutin, and two new polyacylated sucroses, prunoses i and ii, were isolated together with 11 known constituents. the structures of 2' '-o-acetylrutin, 2' '-o-acetyl-3'-o-methylrutin, and prunoses i and ii were determined on the basis of chemical and ... | 2002 | 12193020 |
| identification of sugar-tolerant yeasts isolated from high-sugar fermented vegetable extracts. | in japan, high-sugar fermented vegetable extracts are novel functional food products for which sugar-tolerant yeasts are employed during processing. in order to understand the yeast distribution in these foods and their role in the functionality of such foods, we isolated sugar-tolerant yeasts from nine sample products, together with one sample each of fermented extract of ume (japanese apricot) and honey. twenty-three strains were identified as zygosaccharomyces rouxii; one strain as z. bailii; ... | 1997 | 12501352 |
| [relation between the combination among the chief components of ephedra, chinese cinnamon, japanese apricot seeds and their pharmacological actions]. | | 1964 | 14140143 |
| suppressive effect of the sos-inducing activity of chemical mutagen by citric acid esters from prunus mume sieb. et zucc. using the salmonella typhimurium ta1535/psk1002 umu test. | a methanol extract from prunus mume sieb. et zucc. showed a suppressive effect of the sos-inducing activity on the mutagen 3-amino-1,4-dimethyl-sh-pyrido[4,3-b]indole(trp-p-1) in the salmonella typhimurium ta1535/psk1002 umu test. the methanol extract was re-extracted with hexane, dichloromethane, ethyl acetate, butanol and water. the dichloromethane and ethyl acetate fractions showed suppressive effect. suppressive compounds were isolated by silica gel column chromatography and identified as tr ... | 2003 | 14526909 |
| intestinal sglt1-mediated absorption and metabolism of benzyl beta-glucoside contained in prunus mume: carrier-mediated transport increases intestinal availability. | the intestinal absorption of benzyl beta-glucoside (bnz beta glc) contained in the fruit of prunus mume sieb. et zucc. (rosaceae), which is traditionally used as a medicinal food in japan, was studied in rat intestines. bnz beta glc was absorbed from the mucosal to serosal sides. its metabolite, benzyl alcohol (bal), was also detected on both the mucosal and serosal sides. in the presence of phloridzin (na(+)/glucose cotransporter (sglt1) inhibitor) or in the absence of na+ (driving force), bnz ... | 2005 | 15716003 |
| suppressive effects of fruit-juice concentrate of prunus mume sieb. et zucc. (japanese apricot, ume) on helicobacter pylori-induced glandular stomach lesions in mongolian gerbils. | helicobacter pylori (hp) infection is an important factor in human gastric disorders, including chronic active gastritis, peptic ulcers, intestinal metaplasia and cancer. since epidemiologic studies overwhelmingly agree on a protective influence of fruits and vegetables in reducing the risk of gastric neoplasia and processed foods made from prunus mume sieb. et zucc. (japanese apricot or "ume" in japanese) are traditionally known for their miscellaneous medical effects, in the present study we i ... | 2005 | 16235996 |
| asian prunus viruses: new related members of the family flexiviridae in prunus germplasm of asian origin. | serological reactivity to plum pox virus (ppv) antisera has been described in several prunus sources of asian origin that are free of ppv infection. using polyvalent or specific pcr assays, the presence of three closely related agents in two of these sources, prunus mume cv. bungo and p. persica cv. ku chu'a hung, was demonstrated. similarities in genome organization and sequence comparisons indicate that these agents should be regarded as members of the genus foveavirus, their only singular tra ... | 2006 | 16621102 |
| purification and characteristics of sorbitol-6-phosphate dehydrogenase from loquat leaves. | to study the role of sorbitol-6-phosphate dehydrogenase in sorbitol synthesis in leaves of rosaceous plants, properties of the enzyme and its presence in several plants in the family was investigated. the activity of the enzyme, which catalyzes an nadp-dependent oxidation of the substrate to glucose-6-phosphate, was detected in leaves of prunus mume, prunus persica, rhaphiolepsis indica, sorbus aucuparia, cydonia oblonga, photinia glabra, sorbaria kirilowii, and spiraea thunbergii.the enzyme was ... | 1981 | 16661650 |
| self-compatible peach (prunus persica) has mutant versions of the s haplotypes found in self-incompatible prunus species. | this study demonstrates that self-compatible (sc) peach has mutant versions of s haplotypes that are present in self-incompatible (si) prunus species. all three peach s haplotypes, s (1), s (2), and s (2m), found in this study encode mutated pollen determinants, sfb, while only s (2m) has a mutation that affects the function of the pistil determinant s-rnase. a cysteine residue in the c5 domain of the s (2m)-rnase is substituted by a tyrosine residue, thereby reducing rnase stability. the peach ... | 2007 | 17006593 |
| effect of the folk remedy, bainiku-ekisu, a concentrate of prunus mume juice, on helicobacter pylori infection in humans. | bainiku-ekisu, a concentrate of japanese apricot (prunus mume) juice, is a traditional japanese folk remedy for treatment of dyspepsia since more than a thousand years ago. fujita et al. previously reported in vitro antibacterial effect of bainiku-ekisu to helicobacter pylori. we conducted an in vivo pilot study to evaluate the possibility that bainiku-ekisu may have an antibacterial effect on h. pylori in the human stomach. | 2006 | 17083382 |
| isolation and structural determination of squalene synthase inhibitor from prunus mume fruit. | squalene synthase plays an important role in the cholesterol biosynthetic pathway. inhibiting this enzyme in hypercholesterolemia can lower not only plasma cholesterol but also plasma triglyceride levels. a squalene synthase inhibitor was screened from prunus mume fruit, and then purified via sequential processes of ethanol extraction, hp-20 column chromatography, ethyl acetate extraction, silica gel column chromatography, and crystallization. the squalene synthase inhibitor was identified as ch ... | 2007 | 18167444 |
| in vitro inhibition of human influenza a virus infection by fruit-juice concentrate of japanese plum (prunus mume sieb. et zucc). | using a plaque reduction assay, treatment of human influenza a viruses with the fruit-juice concentrate of japanese plum (prunus mume sieb. et zucc) showed strong in vitro anti-influenza activity against human influenza a viruses before viral adsorption, but not after viral adsorption, with 50% inhibitory concentration (ic50) values against a/pr/8/34 (h1n1) virus, a/aichi/2/68 (h3n2) virus and a/memphis/1/71 (h3n2) virus of 6.35+/-0.17, 2.84+/-1.98 and 0.53+/-0.10 microg/ml, respectively. the pl ... | 2008 | 18310920 |
| mk615 inhibits pancreatic cancer cell growth by dual inhibition of aurora a and b kinases. | to investigate the anti-neoplastic effect of mk615, an anti-neoplastic compound isolated from japanese apricot, against human pancreatic cancer cells in vitro. | 2008 | 18322951 |
| memory-improving effect of formulation-mss by activation of hippocampal mapk/erk signaling pathway in rats. | mss, a comprising mixture of maesil (prunus mume sieb. et zucc) concentrate, disodium succinate and span80 (3.6:4.6 :1 ratio) showed a significant improvement of memory when daily administered (460 mg/kg day, p.o.) into the normal rats for 3 weeks. during the spatial learning of 4 days in morris water maze test, both working memory and short-term working memory index were significantly increased when compared to untreated controls. we investigated a molecular signal transduction mechanism of mss ... | 2008 | 18377729 |
| screening of korean medicinal plants for possible osteoclastogenesis effects in vitro. | bone undergoes continuous remodeling through bone formation and resorption, and maintaining the balance for skeletal rigidity. bone resorption and loss are generally attributed to osteoclasts. differentiation of osteoclasts is regulated by receptor activator of nuclear factor nf-kb ligand (rankl), a member of tumor necrosis factor family. when the balance is disturbed, pathological bone abnormality ensues. through the screening of traditional korean medicinal plants, the effective molecules for ... | 2008 | 18850234 |
| triterpenes augment the inhibitory effects of anticancer drugs on growth of human esophageal carcinoma cells in vitro and suppress experimental metastasis in vivo. | the antineoplastic effects of combinations of anticancer drugs (5-fluorouracil, irinotecan and cisplatin) and triterpenes (ursolic acid, betulinic acid, oleanolic acid and a japanese apricot extract (jae) containing triterpenes) on esophageal squamous carcinoma cells were examined by the wst-8 (2-(2-methoxy- 4-nitrophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2h-tetrazolium, monosodium salt) assay in vitro and by an animal model in vivo. triterpenes and jae showed additive and synergistic cyt ... | 2009 | 19462449 |
| mk615 attenuates porphyromonas gingivalis lipopolysaccharide-induced pro-inflammatory cytokine release via mapk inactivation in murine macrophage-like raw264.7 cells. | the japanese apricot, known as ume in japanese, has been a traditional japanese medicine for centuries, and is a familiar and commonly consumed food. the health benefits of ume are now being widely recognized and have been strengthened by recent studies showing that mk615, an extract of compounds from ume, has strong anticancer and anti-inflammatory effects. however, the potential role of mk615 in the periodontal field remains unknown. here, we found that mk615 significantly reduced the producti ... | 2009 | 19706286 |
| cryo-banking of prunus mume pollen and its application in cross-breeding. | the mei (prunus mume sieb. et zucc.) is one of the most widely used landscape plants and important germplasm resources in china. the study of pollen cryopreservation and the construction of a pollen cryo-bank have great importance in mei research. from 2003 to 2007 we cryopreserved pollen from 51 mei cultivars. in vitro germination of cryopreserved pollen was not significantly different from that of fresh pollen, even after four years of storage in liquid nitrogen. cryopreserved pollen of 19 cul ... | 2009 | 19750240 |
| fermented maesil (prunus mume) with probiotics inhibits development of atopic dermatitis-like skin lesions in nc/nga mice. | maesil (prunus mume siebold & zucc.), a potential source of free radical scavengers and inhibitor of pro-inflammatory mediators, is used in traditional korean medical preparations as a remedy for skin disorders as have probiotics. the action of a probiotic fermented maesil preparation on the development of atopic dermatitis (ad)-like skin lesions was determined in a nc/nga mouse model as an initial step towards the development of a therapeutic feed supplement for use in dogs. continuous ingestio ... | 2010 | 20141605 |
| antimicrobial activity of chinese medicine herbs against common bacteria in oral biofilm. a pilot study. | twenty traditional chinese medicines (tcm) were evaluated for their antimicrobial activity against four common oral bacteria. tcms were tested for sensitivity against streptococcus mitis, streptococcus sanguis, streptococcus mutans and porphyromonas gingivalis. aliquots of suspension of each bacterial species were inoculated onto a horse blood agar plate with tcms soaked separately on 6mm paper disks. the plates were incubated for 48h anaerobically and the mean diameters of growth inhibition of ... | 2010 | 20418062 |
| immune-enhancing effect of fermented maesil (prunus mume siebold & zucc.) with probiotics against bordetella bronchiseptica in mice. | maesil (prunus mume) has long been used as a traditional drug and healthy food in east asian countries. it possesses a number of beneficial biological activities including potential antimicrobial effects against pathogens. probiotics also have antibacterial effects. moreover, some probiotics have an important role in regulating the immune system. the present study evaluated the immune enhancing effects of fermented maesil with probiotics (saccharomyces cerevisiae, bacillus subtilis and lactobaci ... | 2010 | 20453453 |
| mutagenicity and safety evaluation of ethanolic extract of prunus mume. | the ethanolic extract of prunus mume (epm) is a novel polyphenol preparation derived from branches (with leaves) of prunus mume, which could be used as a functional ingredient for antioxidant and antiobesity therapy. the purpose of this study was to evaluate the safety of epm. an epm was prepared and evaluated for oral acute and subacute toxicity in sprague-dawley rats, while its mutagenic potential was assessed by a reverse mutation test using salmonella typhimurium, by a bone marrow cell micro ... | 2009 | 20492134 |
| inhibitory effects of japanese apricot (prunus mume siebold et zucc.; ume) on helicobacter pylori-related chronic gastritis. | we investigated the correlation between japanese apricot (ja) intake and helicobacter pylori-related chronic atrophic gastritis (cag). | 2010 | 20517325 |
| analysis of expressed sequence tags from prunus mume flower and fruit and development of simple sequence repeat markers. | expressed sequence tag (est) has been a cost-effective tool in molecular biology and represents an abundant valuable resource for genome annotation, gene expression, and comparative genomics in plants. | 2010 | 20626882 |
| dietary supplementation with a probiotic fermented four-herb combination enhances immune activity in broiler chicks and increases survivability against salmonella gallinarum in experimentally infected broiler chicks. | herbs including curcuma longa, houttuynia cordata, prunus mume and rubus coreanus have potential immune enhancing and antimicrobial effects. probiotics also have antibacterial effects, and some are important in regulating the immune system. the aims of the present study were to evaluate the immune enhancing effects of a probiotic fermented four-herb combination (pfh) in broiler chicks and to demonstrate the prophylactic effect of pfh against salmonella gallinarum in experimentally infected broil ... | 2010 | 20675965 |
| mk615, a prospective anti-proliferative agent, enhances cd4/cd8 ratio after exposure to irradiation. | recently, it was found that mk615 possessed an anti-proliferative ability on treated cancer cells as a consequence of triterpenoid compounds. it is well known that radiation affects cellular-mediated immunity in cancer patients who are treated with radiotherapy. similarly, the ability of triterpenoid compounds to enhance the cellular-mediated immunity has been observed. therefore, in the present study, we attempted to investigate the effect of mk615 on both cancer cells and cellular-mediated imm ... | 2010 | 20937010 |
| mk615 decreases rage expression and inhibits tage-induced proliferation in hepatocellular carcinoma cells. | to investigate the proliferative effect of advanced glycation end-products (ages) and the role of their cellular receptor (rage) on hepatocellular carcinoma (hcc) cells, and the inhibitory effects of mk615, an extract from japanese apricot, against ages were also evaluated. | 2010 | 21072897 |
| inhibition of proliferation by agricultural plant extracts in seven human adult t-cell leukaemia (atl)-related cell lines. | adult t-cell leukaemia (atl) is caused by human t-cell leukaemia virus type i (htlv-i) infection and is resistant to conventional chemotherapy. we evaluated the inhibitory effects of agricultural plants on the proliferation of seven atl-related human leukaemia cells, using three atl cell lines (ed, su9t01 and s1t), two human t-cell lines transformed by htlv-i infection (hut-102 and mt-2) and two htlv-i-negative human t-cell acute lymphoblastic leukaemia cell lines (jurkat and molt-4). a total of ... | 2011 | 21293936 |
| prunus mume extract exhibits antimicrobial activity against pathogenic oral bacteria. | prunus mume is a common fruit in asia, which has been used in traditional chinese medicine. in this study, we focused on the antimicrobial properties of prunus mume extract against oral pathogens related to dental caries and periodontal diseases. | 2011 | 21401748 |
| mk615: a new therapeutic approach for the treatment of oral disease. | the oral cavity is inhabited by over 500 different bacterial species. dental caries and periodontitis are major bacterial infectious diseases in the oral cavity. prunus mume sieb. et zucc., which is a variety of japanese apricot known as ume in japanese, has been a traditional japanese medicine for centuries, and is a familiar and commonly consumed food. the health benefits of ume are now being widely recognized. recent studies showed that mk615, an extract of compounds from ume, has strong anti ... | 2011 | 21565449 |
| effects of new dietary fiber from japanese apricot (prunus mume sieb. et zucc.) on gut function and intestinal microflora in adult mice. | much attention has been focused recently on functional foods. ume, the japanese name for the apricot of prunus mume sieb. et zucc., is an example of a japanese traditional functional food. there are, however, few reports on the effects of fiber from this fruit on bowel function. with this objective, we prepared ume fiber to test the hypothesis that it can change gut function and intestinal flora in mice. mice were fed an ume fiber (uf) or cellulose (cf) diet (control) for 40 days. the fecal weig ... | 2011 | 21731428 |
| A study of consumers' perceptions and prediction of consumption patterns for generic health functional foods. | The Korea Food and Drug Administration (KFDA) revised the Health Functional Food Act in 2008 and extended the form of health functional foods to general food types. Therefore, this study was performed to investigate consumers' perceptions of the expanded form of health functional food and to predict consumption patterns. For this study, 1,006 male and female adults aged 19 years and older were selected nationwide by multi-stage stratified random sampling and were surveyed in 1:1 interviews. The ... | 2011 | 21994526 |
| a natural therapeutic approach for the treatment of periodontitis by mk615. | periodontitis is a chronic inflammatory disease that affects the tooth-supporting tissues. gingival fibroblasts are the most abundant cells in periodontal tissues and they participate actively in the host inflammatory response to periodontal pathogens that is known to mediate local tissue destruction in periodontitis. the japanese apricot, known as ume in japanese, has been a traditional japanese medicine for centuries and is a familiar and commonly consumed food. the health benefits of ume are ... | 2015 | 26305447 |
| characterization and comparison of the cpk gene family in the apple (malus × domestica) and other rosaceae species and its response to alternaria alternata infection. | as one of the ca2+ sensors, calcium-dependent protein kinase (cpk) plays vital roles in immune and stress signaling, growth and development, and hormone responses, etc. recently, the whole genome of apple (malus × domestica), pear (pyrus communis), peach (prunus persica), plum (prunus mume) and strawberry (fragaria vesca) in rosaceae family has been fully sequenced. however, little is known about the cpk gene family in these rosaceae species. in this study, 123 cpk genes were identified from fiv ... | 2016 | 27186637 |
| study of the antibacterial efficacy of bainiku-ekisu against pathogens. | the research was undertaken to determine the bacteriostatic effects of the concentrate of japanese apricot juice (bainiku-ekisu), which is a popular health food in taiwan and japan, on enterococcus faecalis atcc 29212, staphylococcus aureus atcc 25923, and escherichia coli atcc 25922. the results show that e. faecalis, s. aureus, and e. coli could be killed or inhibited by bainiku-ekisu at concentrations between 1.0 and 10.0 mg/ml. the minimum inhibitory concentration (mic) was 1 mg/ml for all s ... | 2014 | 26904733 |
| overexpression of prunus mume dehydrin genes in tobacco enhances tolerance to cold and drought. | dehydrins, known as group 2 or d-11 family late-embryogenesis-abundant (lea) proteins, play important roles in plant growth and stress tolerance. six dehydrin genes were previously identified from the genome of prunus mume. in this study, five of them (pmlea8, pmlea10, pmlea19, pmlea20, and pmlea29) were cloned from cold-resistant p. mume 'beijingyudie'. real-time rt-pcr analysis indicated that all these genes could be up-regulated by one or several treatments (aba, sa, low temperature, high tem ... | 2017 | 28224001 |
| sep-class genes in prunus mume and their likely role in floral organ development. | flower phylogenetics and genetically controlled development have been revolutionised during the last two decades. however, some of these evolutionary aspects are still debatable. mads-box genes are known to play essential role in specifying the floral organogenesis and differentiation in numerous model plants like petunia hybrida, arabidopsis thaliana and antirrhinum majus. sepallata (sep) genes, belonging to the mads-box gene family, are members of the abcde and quartet models of floral organ d ... | 2017 | 28086797 |
| volatile n-nitrosamine inhibition after intake korean green tea and maesil (prunus mume sieb. et zacc.) extracts with an amine-rich diet in subjects ingesting nitrate. | the formation of carcinogenic nitrosamines under simulated gastric conditions was studied during the incubation of amine rich food and nitrate, and its possible inhibition by adding kumquat, sweet orange, strawberry, garlic, kale juices, maesil (prunus mume) and green tea extracts. the strawberry, kale juices, maesil and green tea extracts were equally effective in reducing the formation of n-nitrosodimethylamine (ndma). the fruits of p. mume sieb. et zacc. (korean name, maesil) have been used a ... | 2002 | 12065217 |
| epigenetic regulation of bud dormancy events in perennial plants. | release of bud dormancy in perennial plants resembles vernalization in arabidopsis thaliana and cereals. in both cases, a certain period of chilling is required for accomplishing the reproductive phase, and several transcription factors with the mads-box domain perform a central regulatory role in these processes. the expression of dormancy-associated mads-box (dam)-related genes has been found to be up-regulated in dormant buds of numerous plant species, such as poplar, raspberry, leafy spurge, ... | 2014 | 24917873 |
| isolation and characterization of a terminal flower 1 homolog from prunus serotina ehrh. | flowering control is one of the several strategies for gene containment of transgenic plants. terminal flower 1 (tfl1) is known to be involved in the transcriptional repression of genes for inflorescence development. two tfl1 transcripts with different 3' utr were cloned from black cherry (prunus serotina ehrh.) using reverse transcription-polymerase chain reaction (rt-pcr) and rapid amplification of cdna ends (race). corresponding to the two tfl1 transcripts, two pstfl1 gene sequences, 1248 bp ... | 2013 | 23956129 |
| shortening tobacco life cycle accelerates functional gene identification in genomic research. | definitive allocation of function requires the introduction of genetic mutations and analysis of their phenotypic consequences. novel, rapid and convenient techniques or materials are very important and useful to accelerate gene identification in functional genomics research. here, over-expression of pmft (prunus mume), a novel ft orthologue, and ptft (populus tremula) lead to shortening of the tobacco life cycle. a series of novel short life cycle stable tobacco lines (30-50 days) were develope ... | 2012 | 23107371 |
| evaluation of fruit intake and its relation to body mass index of adolescents. | diets high in fruits and vegetables are recommended to maintain health. however, accurate fruit intake evaluation is hard and high sugar content in most of the fruits suggest possible negative relationships with health indices. the purpose of the present study was to evaluate the fruit intake status of adolescents and to examine the relationship between fruit intake and body mass index (bmi). for this, 400 middle and high school students were surveyed for their fruit eating attitude, preference, ... | 2014 | 25136540 |
| genome-wide identification and comparative analysis of the cation proton antiporters family in pear and four other rosaceae species. | the monovalent cation proton antiporters (cpas) play essential roles in plant nutrition, development, and signal transduction by regulating ion and ph homeostasis of the cell. the cpas of plants include the na(+)/h(+) exchanger, k(+) efflux antiporter, and cation/h(+) exchanger families. however, currently, little is known about the cpa genes in rosaceae species. in this study, 220 cpa genes were identified from five rosaceae species (pyrus bretschneideri, malus domestica, prunus persica, fragar ... | 2016 | 27193473 |
| species-specific duplications driving the recent expansion of nbs-lrr genes in five rosaceae species. | disease resistance (r) genes from different rosaceae species have been identified by map-based cloning for resistance breeding. however, there are few reports describing the pattern of r-gene evolution in rosaceae species because several rosaceae genome sequences have only recently become available. | 2015 | 25759136 |
| genome-wide identification and comparative analysis of the heat shock transcription factor family in chinese white pear (pyrus bretschneideri) and five other rosaceae species. | heat shock transcription factors (hsfs), which act as important transcriptional regulatory proteins in eukaryotes, play a central role in controlling the expression of heat-responsive genes. at present, the genomes of chinese white pear ('dangshansuli') and five other rosaceae fruit crops have been fully sequenced. however, information about the hsfs gene family in these rosaceae species is limited, and the evolutionary history of the hsfs gene family also remains unresolved. | 2015 | 25604453 |
| characterization of the lipoxygenase (lox) gene family in the chinese white pear (pyrus bretschneideri) and comparison with other members of the rosaceae. | lipoxygenases (loxs), a type of non-haem iron-containing dioxygenase, are ubiquitous enzymes in plants and participate in the formation of fruit aroma which is a very important aspect of fruit quality. amongst the various aroma volatiles, saturated and unsaturated alcohols and aldehydes provide the characteristic aroma of the fruit. these compounds are formed from unsaturated fatty acids through oxidation, pyrolysis and reduction steps. this biosynthetic pathway involves at least four enzymes, i ... | 2014 | 24906560 |
| genome-wide characterization and linkage mapping of simple sequence repeats in mei (prunus mume sieb. et zucc.). | because of its popularity as an ornamental plant in east asia, mei (prunus mume sieb. et zucc.) has received increasing attention in genetic and genomic research with the recent shotgun sequencing of its genome. here, we performed the genome-wide characterization of simple sequence repeats (ssrs) in the mei genome and detected a total of 188,149 ssrs occurring at a frequency of 794 ssr/mb. mononucleotide repeats were the most common type of ssr in genomic regions, followed by di- and tetranucleo ... | 2013 | 23555708 |
| first report of cherry virus a infecting prunus mume in south korea. | we report the detection of cherry virus a (cva) in a prunus mume sample using illumina hiseq 2500 paired-end rna sequencing. cva isolate oc shared highest sequence identity with cva isolate j, which was recently identified in p. armeniaca in japan. to the best of our knowledge, this is the first report of cva infecting p. mume in korea and the first complete genome sequence of cva isolated from p. mume in the world. | 2017 | 28770251 |
| identification and characterization of cyp79d16 and cyp71an24 catalyzing the first and second steps in l-phenylalanine-derived cyanogenic glycoside biosynthesis in the japanese apricot, prunus mume sieb. et zucc. | japanese apricot, prunus mume sieb. et zucc., belonging to the rosaceae family, produces as defensive agents the cyanogenic glycosides prunasin and amygdalin, which are presumably derived from l-phenylalanine. in this study, we identified and characterized cytochrome p450s catalyzing the conversion of l-phenylalanine into mandelonitrile via phenylacetaldoxime. full-length cdnas encoding cyp79d16, cyp79a68, cyp71an24, cyp71ap13, cyp71au50, and cyp736a117 were cloned from p. mume ‘nanko’ using pub ... | 2014 | 25015725 |
| ribosome inactivating proteins from rosaceae. | ribosome-inactivating proteins (rips) are widespread among higher plants of different taxonomic orders. in this study, we report on the rip sequences found in the genome/transcriptome of several important rosaceae species, including many economically important edible fruits such as apple, pear, peach, apricot, and strawberry. all rip domains from rosaceae share high sequence similarity with conserved residues in the catalytic site and the carbohydrate binding sites. the genomes of malus domestic ... | 0 | 27556443 |
| japanese apricot improves symptoms of gastrointestinal dysmotility associated with gastroesophageal reflux disease. | to investigate the effects of japanese apricot (ja) consumption on gastroesophageal reflux disease (gerd)-related symptoms. | 2015 | 26185391 |
| genome-wide characterization, evolution, and expression analysis of the leucine-rich repeat receptor-like protein kinase (lrr-rlk) gene family in rosaceae genomes. | leucine-rich repeat receptor-like protein kinase (lrr-rlk) is the largest gene family of receptor-like protein kinases (rlks) and actively participates in regulating the growth, development, signal transduction, immunity, and stress responses of plants. however, the patterns of lrr-rlk gene family evolution in the five main rosaceae species for which genome sequences are available have not yet been reported. in this study, we performed a comprehensive analysis of lrr-rlk genes for five rosaceae ... | 2017 | 29017442 |
| genome-wide analysis suggests the relaxed purifying selection affect the evolution of wox genes in pyrus bretschneideri, prunus persica, prunus mume, and fragaria vesca. | wuschel-related homeobox (wox) family is one of the largest group of transcription factors (tfs) specifically found in plant kingdom. wox tfs play an important role in plant development processes and evolutionary novelties. although the roles of woxs in arabidopsis and rice have been well-studied, however, little are known about the relationships among the main clades in the molecular evolution of these genes in rosaceae. here, we carried out a genome-wide analysis and identified 14, 10, 10, and ... | 2017 | 28663757 |
| genome-wide analysis suggests high level of microsynteny and purifying selection affect the evolution of ein3/eil family in rosaceae. | the ethylene-insensitive3/ethylene-insensitive3-like (ein3/eil) proteins are a type of nuclear-localized protein with dna-binding activity in plants. although the ein3/eil gene family has been studied in several plant species, little is known about comprehensive study of the ein3/eil gene family in rosaceae. in this study, ten, five, four, and five ein3/eil genes were identified in the genomes of pear (pyrus bretschneideri), mei (prunus mume), peach (prunus persica) and strawberry (fragaria vesc ... | 2017 | 28584725 |
| a new insight into the evolution and functional divergence of sweet transporters in chinese white pear (pyrus bretschneideri). | sweet genes are a recently identified plant gene family that play an indispensable role in sugar efflux. however, no systematic study has been performed in pear. in this research, 18 sweet transporters identified in pear, almost twice the number found in woodland strawberry and japanese apricot, were divided into four clades. conserved motifs and six exons of the sweet transporters were found in six species. sweet transporters contained seven transmembrane segments (tmss) that evolved from an in ... | 2017 | 28339862 |
| induction of apoptosis by ethanol extract of prunus mume in u937 human leukemia cells through activation of caspases. | prunus mume (p. mume), a traditional drug and health food in korea, japan and china, possesses various pharmacological activities that include a potential source of free radical scavenging, anti-viral, anti-microbial, anti-inflammatory and anti-cancer activities. however, the cellular and molecular mechanisms of apoptosis induction by p. mume in human cancer cells are poorly understood. in the present study, we conducted an investigation of the pro-apoptotic effects of an ethanol extract of p. m ... | 2011 | 21725606 |
| functional and expressional analyses of pmdam genes associated with endodormancy in japanese apricot (prunus mume). | bud endodormancy in woody plants plays an important role in their perennial growth cycles. we previously identified a mads-box gene, prunus mume dormancy associated mads6 (pmdam6), expressed in the endodormant lateral buds of japanese apricot (p. mume) as a candidate for the dormancy-controlling gene. in this study, we demonstrated the growth inhibitory functions of pmdam6 by overexpressing it in transgenic poplar (populus tremula x tremuloides). transgenic poplar plants constitutively expressin ... | 2011 | 21795580 |
| effect of jasmonates on ethylene biosynthesis and aroma volatile emission in japanese apricot infected by a pathogen (colletotrichum gloeosporioides). | the effects of the application of the jasmonic acid derivative n-propyl dihydrojasmonate (pdj) on ethylene biosynthesis, volatile compounds, and endogenous jasmonic acid (ja) and methyl jasmonate (meja) were examined in japanese apricot (prunus mume sieb.) infected by a pathogen (colletotrichum gloeosporioides). the fruit were dipped into 0.4 mm pdj solution before inoculation with the pathogen and stored at 25 °c for 6 days. the inoculation induced an increase in 1-aminocyclopropane-1-carboxyli ... | 2011 | 21599017 |
| prunus mume extract ameliorates exercise-induced fatigue in trained rats. | this study evaluated the effects of prunus mume extract on exercise-induced fatigue recovery in a trained rat model. male sprague-dawley rats were raised either on a control diet (ec) or on diets supplemented with 0.15% (0.15ep), 0.3% (0.3ep), or 0.9% (0.9ep) prunus mume extract for 4 weeks (n = 18). each dietary group was divided into two subgroups; at the end of the experimental period, one subgroup was sacrificed immediately after a 1-hour exercise, and the other subgroup was sacrificed after ... | 2008 | 18800892 |
| trans-specific s-rnase and sfb alleles in prunus self-incompatibility haplotypes. | self-incompatibility in the genus prunus is controlled by two genes at the s-locus, s-rnase and sfb. both genes exhibit the high polymorphism and high sequence diversity characteristic of plant self-incompatibility systems. deduced polypeptide sequences of three myrobalan and three domestic plum s-rnases showed over 97% identity with s-rnases from other prunus species, including almond, sweet cherry, japanese apricot and japanese plum. the second intron, which is generally highly polymorphic bet ... | 2008 | 17989997 |
| rapid determination of the main organic acid composition of raw japanese apricot fruit juices using near-infrared spectroscopy. | the potential of near-infrared (nir) spectroscopy to rapidly determine citric and malic acid contents of raw japanese apricot (japanese "ume", also known as the japanese plum) fruit juice was investigated. in total, 314 raw juice samples with different organic acid compositions were collected over a long growth period, and spectra (1100-1850 nm) of these samples were acquired using an nir spectrophotometer with a 1-mm path length. calibrations were performed using a partial least-squares regress ... | 2006 | 17177483 |
| inhibition of helicobacter pylori motility by (+)-syringaresinol from unripe japanese apricot. | a methanol extract from unripe japanese apricot showed inhibitory activity of helicobacter pylori motility. inhibitory compound 1 was isolated and identified as (+)-syringaresinol (1) by spectoroscopic means. (+)-syringaresinol (1) inhibited >90% of the h. pylori motility at a concentration of 500 microg/ml and the ic50 value was 50 microg/ml. | 2006 | 16394533 |
| [spectrometric determination of trace elements in 'jinguang' prunus mume var. bungo of different growth periods]. | a study was carried out on the content of trace elements such as ca, fe, zn, mn and cu of prunus mume var. bungo in different growth periods by wfx-110 atomic absorption spectrometry. the results indicated that the linear relationships of different elements within the limits of working curves are good and the range of the recovery is 98% -105%, hence showing that the results are satisfactory. the total content of these five trace elements increases as the fruit grows, but the concentration is re ... | 2005 | 16241076 |
| effects of benzyl glucoside and chlorogenic acid from prunus mume on adrenocorticotropic hormone (acth) and catecholamine levels in plasma of experimental menopausal model rats. | to investigate the effectiveness of benzyl beta-d-glucopyranoside (bg) and chlorogenic acid (ca), the constituents of the fruit of prunus mume, for relieving tension in experimental menopausal model rats (m-rats) caused by ether stress, the effects of bg and ca on adrenocorticotropic hormone (acth) and catecholamine (adrenaline, noradrenaline, and dopamine) levels were examined in the plasma of m-rats. caffeic acid, quinic acid, and rosmarinic acid, which are compounds structurally related to ca ... | 2004 | 14709918 |
| genetic diversity in apricot revealed by aflp markers: species and cultivar comparisons. | the genetic diversity of apricot ( prunus armeniaca; 2n = 16) was studied using aflp markers. forty seven apricot cultivars were selected from the following geographic regions: europe, north america, north africa, turkey, iran and china. five ecori- msei aflp primer combinations revealed 416 legible bands, of which 379 were polymorphic markers. a similarity matrix was prepared using the simple matching coefficient of similarity. a upgma dendrogram demonstrated a gradient of decreasing genetic di ... | 2002 | 12582532 |
| improved superoxide-generating system suitable for the assessment of the superoxide-scavenging ability of aqueous extracts of food constituents using ultraweak chemiluminescence. | in the interest of developing a simple and rapid ultraweak chemiluminescence assay for assessing the superoxide (o(2)(-))-scavenging activities of various aqueous extracts of food constituents, a specific and stable o(2)(-)-generating system was sought. reported herein is the obtainment for the first time of a specific and stable o(2)(-)-generating system consisting of methylglyoxal (mg), a reactive 2-oxo aldehyde and arginine, which has been shown to produce much steadier lucigenin-based chemil ... | 2003 | 12502385 |
| fruit-juice concentrate of asian plum inhibits growth signals of vascular smooth muscle cells induced by angiotensin ii. | bainiku-ekisu, the fruit-juice concentrate of the oriental plum (prunus mume) has recently been shown to improve human blood fluidity. we have shown that angiotensin ii (angii) stimulates growth of vascular smooth muscle cells (vsmcs) through epidermal growth factor (egf) receptor transactivation that involves reactive oxygen species (ros) production. to better understanding the possible cardiovascular protective effect of bainiku-ekisu, we have studied whether bainiku-ekisu inhibits angii-induc ... | 2002 | 12467906 |
| rapid and specific detection of hydroxyl radical using an ultraweak chemiluminescence analyzer and a low-level chemiluminescence emitter: application to hydroxyl radical-scavenging ability of aqueous extracts of food constituents. | with the availability of an ultraweak chemiluminescence analyzer, it is possible to monitor the production of a specific oxygen-derived reactive species, such as hydroxyl radical ((*)oh), whenever a suitable chemiluminescent probe is obtainable. reported herein is the development of a rapid and specific method for detecting (*)oh production using a specific probe, indoxyl-beta-glucuronide (ibg), a low-level chemiluminescence emitter. using the fenton reagent as a source of (*)oh, it was shown th ... | 2001 | 11368567 |
| biological activity and structural characterization of alkaline-soluble polysaccharides from the kernels of prunus mume sieb. et zacc. | the fruits of prunus mume sieb. et zacc. (japanese name, ume) have been used as a traditional drug and health food. in order to study the active components of p. mume, the polysaccharide fractions were extracted with cold water, hot water and aqueous sodium hydroxide from the kernels of p. mume. we found that some of the polysaccharide fractions exhibited various types of biological activities such as mitogenesis, activation of the alternative pathway of complement and activation of clot formati ... | 1994 | 8019503 |
| the screening of chinese crude drugs for ca2+ antagonist activity: identification of active principles from the aerial part of pogostemon cablin and the fruits of prunus mume. | hot aqueous extracts of 134 chinese crude drugs were subjected to screening for inhibitory activity on k+ contracture of guinea pig taenia coli, and significant activity was observed in 17 crude drugs. chemical investigations of two crude drugs, kakko and ubai, which originate from pogostemon cablin and prunus mume, respectively, were undertaken, and patchouli alcohol (i) and 5-(hydroxymethyl)-2-furaldehyde (ii) were identified as their active principles, respectively. | 1989 | 2743480 |
| [relation between helicobacter pylori and pathogenesis of chronic atrophic gastritis and the research of its prevention and treatment]. | the total detectable rate of helicobacter pylori (hp) of 485 patients suffering from gastric diseases was 59.6%. the hp in gastric mucosa of chronic atrophic gastritis (cag) patients was separated from the cell culture in vitro and transferred successively. the mice were perfused with exciccate alum, and the rabbits with aspirin to injure their gastric mucosa, then hp was perfused. result showed that the change of experimental animals was identical with that of cag patients by means of bacteriol ... | 1992 | 1298465 |
| consumer perception of balsamic vinegar: a cross-cultural study between korea and italy. | understanding cross-cultural differences in food perception is a key issue of food research in order to understand consumer behaviour in different countries. the objective of this study was to explore potential cultural differences of balsamic vinegar perception between korean and italian consumers using the sorted napping method. nine balsamic vinegars different in terms of ingredients, aging time, and origin were evaluated by korean (n=50) and italian (n=49) consumers using sorted napping. fam ... | 0 | 28290319 |
| efficacy of mk615 for the treatment of patients with liver disorders. | to investigate the hepatoprotective effect of mk615, a japanese apricot extract, in an animal model, and its clinical therapeutic effect. | 2012 | 22919243 |
| screening for new hydroxynitrilases from plants. | we established a simple hplc method to determine the activity and stereochemistry of the chiral mandelonitrile synthesized from benzaldehyde and cyanide, and applied it to screen for hydroxynitrile lyase (hnl) activity of plant origin. a total of 163 species of plants among 74 families were examined for (r)- and (s)-hnl activities using the method. we discovered that homogenate of leaves of baliospermum montanum shows (s)-hnl activity, while leaves and seeds from passiflora edulis, and seeds fro ... | 2005 | 16377893 |
| cloning and expression of hydroxynitrile lyase gene from eriobotrya japonica in pichia pastoris. | hydroxynitrile lyase gene (hnl) from eriobotrya japonica was successfully amplified using the method of sefa pcr (self-formed adaptor pcr). the complete sequence was 5.5 kbp in length, including 3100 bp of the upstream promoter region, 1659 bp of the coding sequence, three introns and 315 bp of the downstream transcription terminator. the phylogenetic analysis illustrated that the obtained hnl exhibited 66-70% identity to the reported isozymes from almond, black cherry and japanese apricot. the ... | 2011 | 22000752 |
| new anti-proliferative agent, mk615, from japanese apricot "prunus mume" induces striking autophagy in colon cancer cells in vitro. | to investigate the anti-neoplastic effects of mk615, an extract from the japanese apricot (prunus mume), against colon cancer cells. | 2007 | 18161921 |
| biological screening of 100 plant extracts for cosmetic use (ii): anti-oxidative activity and free radical scavenging activity. | methanol aqueous extracts of 100 plants were screened for anti-oxidative activity using fenton's reagent/ethyl linoleate system and for free radical scavenging activity using the 1,1-diphenyl-2-picryl hydrazyl free radical generating system. the results suggest that 14 plants - alpinia officinarum, areca catechu, brassica alba, cannabis sativa, curcuma longa, curcuma aromatica, eugenia caryophyllata, evodia officinalis, paeonia suffruticosa, rhaphanus sativus, rheum palmatum, rhus verniciflua, t ... | 1997 | 18505484 |
| [melanin synthesis was affected by extracts of 22 kinds chinese herbs of acid taste: an experi- mental study]. | to confirm the inhibitory effect of chinese herbs of acid taste on melanin synthesis. | 2015 | 26159030 |
| the divergence of flowering time modulated by ft/tfl1 is independent to their interaction and binding activities. | flowering locus t (ft) and terminal flower1 (tfl1) proteins share highly conserved amino acid residues but they play opposite regulatory roles in promoting and repressing the flowering response, respectively. previous substitution models and functional analysis have identified several key amino acid residues which are critical for the promotion of flowering. however, the precise relationship between naturally occurring ft/tfl1 homologs and the mechanism of their role in flowering is still unclea ... | 2017 | 28533784 |
| genomics of pear and other rosaceae fruit trees. | the family rosaceae includes many economically important fruit trees, such as pear, apple, peach, cherry, quince, apricot, plum, raspberry, and loquat. over the past few years, whole-genome sequences have been released for chinese pear, european pear, apple, peach, japanese apricot, and strawberry. these sequences help us to conduct functional and comparative genomics studies and to develop new cultivars with desirable traits by marker-assisted selection in breeding programs. these genomics reso ... | 2016 | 27069399 |
| efficacy of a standardized extract of prunus mume in liver protection and redox homeostasis: a randomized, double-blind, placebo-controlled study. | the antioxidant, anti-inflammatory and hepatoprotective effects of prunus mume (pm) have previously been demonstrated. this double-blind, placebo-controlled study was designed to evaluate the influence of two doses of a food supplement, made of 150 mg of a standardized pm extract on liver transaminases, lipid profile, glycemia, neopterin and reduced and oxidized thiols in plasma and erythrocytes, during a 3-month treatment period, in healthy subjects with transaminases levels between 20 and 40 u ... | 2016 | 26952142 |
| Effects of a plum (Prunus mume Siebold and Zucc.) ethanol extract on the immune system in vivo and in vitro. | The effect of a plum ethanol extract (PEE) on immunity was analyzed. An oral administration of PEE increased the interleukin (IL)-12p40 concentration in the serum and T-cell ratio in the spleen. In vitro studies revealed that PEE stimulated IL-12p70 production in peritoneal macrophages and natural killer activity. These findings suggest that PEE enhanced the immune function by stimulating innate immune cells. | 2011 | 21979085 |
| microarray analysis of differentially expressed genes engaged in fruit development between prunus mume and prunus armeniaca. | microarray analysis is a technique that can be employed to provide expression profiles of single genes and new insights to elucidate the biological mechanisms responsible for fruit development. to evaluate expression of genes mostly engaged in fruit development between prunus mume and prunus armeniaca, we first identified differentially expressed transcripts along the entire fruit life cycle by using microarrays spotted with 10,641 ests collected from p. mume and other prunus est sequences. a to ... | 2012 | 23036314 |
| prunus transcription factors: breeding perspectives. | many plant processes depend on differential gene expression, which is generally controlled by complex proteins called transcription factors (tfs). in peach, 1533 tfs have been identified, accounting for about 5.5% of the 27,852 protein-coding genes. these tfs are the reference for the rest of the prunus species. tf studies in prunus have been performed on the gene expression analysis of different agronomic traits, including control of the flowering process, fruit quality, and biotic and abiotic ... | 2015 | 26124770 |
| the s haplotype-specific f-box protein gene, sfb, is defective in self-compatible haplotypes of prunus avium and p. mume. | many prunus species, including sweet cherry and japanese apricot, of the rosaceae, display an s-rnase-based gametophytic self-incompatibility (gsi). the specificity of this outcrossing mechanism is determined by a minimum of two genes that are located in a multigene complex, termed the s locus, which controls the pistil and pollen specificities. sfb, a gene located in the s locus region, encodes an f-box protein that has appropriate s haplotype-specific variation to be the pollen determinant in ... | 2004 | 15272875 |
| hpqtl: a geometric morphometric platform to compute the genetic architecture of heterophylly. | heterophylly, i.e. morphological changes in leaves along the axis of an individual plant, is regarded as a strategy used by plants to cope with environmental change. however, little is known of the extent to which heterophylly is controlled by genes and how each underlying gene exerts its effect on heterophyllous variation. we described a geometric morphometric model that can quantify heterophylly in plants and further constructed an r-based computing platform by integrating this model into a ge ... | 2017 | 28203720 |
| effects of prunus mume siebold & zucc. in the pacemaking activity of interstitial cells of cajal in murine small intestine. | interstitial cells of cajal (iccs) function as pacemaker cells in the gastrointestinal (gi) tract and therefore, serve an important role in regulating gi motility. the effects of a species of plum (prunus mume siebold & zucc.) on cultured icc cluster-induced pacemaker potentials in the mouse small intestine were investigated, and the effects of a methanolic extract of prunus mume (m-pm) on icc pacemaker activities were examined using the whole-cell patch-clamp technique. icc pacemaker membrane p ... | 2017 | 28123510 |
| method for the isolation of citric acid and malic acid in japanese apricot liqueur for carbon stable isotope analysis. | a method for detecting the undeclared addition of acidic ingredients is required to control the authenticity of japanese apricot liqueur. we developed an analytical procedure that minimizes carbon isotope discrimination for measurement of the δ(13)c values of citric and malic acid isolated from japanese apricot liqueur. our results demonstrated that freeze-drying is preferable to nitrogen spray-drying, because it does not significantly affect the δ(13)c values of citric acid and results in small ... | 2017 | 27664615 |
| genome-wide identification, characterization and expression analysis of the tcp gene family in prunus mume. | tcp proteins, belonging to a plant-specific transcription factors family, are known to have great functions in plant development, especially flower and leaf development. however, there is little information about this gene family in prunus mume, which is widely cultivated in china as an ornamental and fruit tree. here a genome-wide analysis of tcp genes was performed to explore their evolution in p. mume. nineteen pmtcps were identified and three of them contained putative mir319 target sites. p ... | 2016 | 27630648 |
| receptor for advanced glycation endproducts signaling cascades are activated in pancreatic fibroblasts, but not in the ins1e insulinoma cell line: are mesenchymal cells major players in chronic inflammation? | the receptor for advanced glycation endproducts (rage) is a pattern recognition receptor that plays an important role in natural immunity. it is suggested that mesenchymal cells are the major players during inflammation. previously, we reported that advanced glycation end products (age), known to be one of the ligands of rage, inhibited glucose-induced insulin secretion from ex vivo pancreatic islets, although the mechanism responsible remains largely unknown. in the present study, we examined t ... | 2016 | 27415824 |