| sulphorhodamine b assay for measuring proliferation of a pigmented melanocyte cell line and its application to the evaluation of crude drugs used in the treatment of vitiligo. | a rapid 96-well plate assay using sulphorhodamine b (srb) protein stain for cell number has been adopted to screen herbs used in traditional treatments of vitiligo for substances capable of stimulating melanocyte proliferation. its applicability to melan-a cells, a mouse pigmented cell line, has been validated. srb assay produced good linearity up to 11 x 10(4) cells/well and interference by melanin present in the cells accounted for less than 10% of the total optical density readings. the intra ... | 1999 | 10433470 |
| [32 cases of postoperative osteogenic sarcoma treated by chemotherapy combined with chinese medicinal herbs]. | 32 cases of postoperative osteogenic sarcoma treated by chemotherapy combined with chinese medicinal herbs were compared with 26 similar cases as control group. the drugs used in chemotherapy consisted of two regimens, ddp and high-dose mtx plus vcr. the results showed that the side effects of chemotherapy in control group were consistent with literatures; while the group treated with chinese medicinal herbs suffered less toxic effects, the difference between two groups was statistically signifi ... | 1993 | 8339032 |
| [clinical and experimental study of the effect of kang er xin-i on viral myocarditis]. | kang er xin-i (kex-i) is a proved recipe used to treat viral myocarditis. it consists of lonicera japonica, ophiopogon japonicus, astragalus membranaceus mainly and possesses the effect of clearing away heat and toxic materials and supplementing the vital energy and nourishing. the clinical study was carried out with kex-i according to a random, paired and cross-over design. coenzyme q10 was used as a control and left ventricular function was observed. the result showed: after being treated with ... | 1991 | 1659497 |
| [anti-arrhythmic effects and electrophysiological properties of ophiopogon total saponins]. | the arrhythmias induced by chloroform-epinephine, bacl2, and aconitine were prevented and antagonized by ophiopogon total saponins (ots) which were extracted from the root of ophiopogon japonicus (thunb) ker-gawl. the incidence of ventricular arrhythmia produced by ligation of the left anterior descending coronary artery was effectively decreased without any changes in the hemodynamic indices of dogs. the electrophysiological effects of ots in vivo and in vitro were studied by means of contact e ... | 1990 | 2275393 |
| [professor ling changquan's experience in treating primary liver cancer: an analysis of herbal medication]. | on the basis of outpatients' medical records concerning primary liver cancer (plc), data of 552 patients (with 2020 effective prescriptions) from the outpatient department of changhai hospital treated by professor ling changquan were collected. the nature, flavor and meridian distribution of the herbs used in the prescriptions were summarized by frequency method, and the features of the herbs used according to syndrome differentiation were analyzed by logistic regression. the couple herbs used w ... | 2008 | 19063833 |
| influence of sulfation on anti-myocardial ischemic activity of ophiopogon japonicus polysaccharide. | ophiopogon japonicus polysaccharide (foj-5) from radix ophiopogonis has shown anti-myocardial ischemic action in vitro and in vivo in our previous studies. in order to clarify the influence of chemical modifications on the action, a series of sulfated foj-5 (foj-5-s) with different substitution degrees were prepared and the anti-myocardial ischemic action of the natural foj-5 and the foj-5-s were studied in vitro and in vivo. langendorff isolated rat hearts and acute myocardial ischemic rats ind ... | 2009 | 19431010 |
| characteristics of sewage sludge and distribution of heavy metal in plants with amendment of sewage sludge. | in order to better understand land application of sewage sludge, the characterization of heavy metals and organic pollutants were investigated in three different sewage sludges in shanghai city, china. it was found that the total concentrations of cd in all of sewage sludge and total concentrations of zn in jinshan sewage sludge, as well as those of zn, cu, and ni in taopu sludge are higher than chinese regulation limit of pollutants for sludge to be used in agriculture. leachability of hg in al ... | 2006 | 17294948 |
| a polysaccharide, mdg-1, induces s1p1 and bfgf expression and augments survival and angiogenesis in the ischemic heart. | ophiopogon japonicus is a traditional chinese medicine used to treat cardiovascular disease. recent studies have confirmed its beneficial properties, but not the mechanism of action. herein, we investigate the anti-ischemic properties of a water-soluble beta-d-fructan (mdg-1) from ophiopogon japonicus, and assess the cytoprotective and proangiogenic effects of mdg-1. mdg-1 protects cardiomyocyte and microvascular endothelial cells (hmec-1) against oxygen glucose deprivation (ogd)-induced cell de ... | 2010 | 20008963 |
| possible mechanism of the anti-inflammatory activity of ruscogenin: role of intercellular adhesion molecule-1 and nuclear factor-kappab. | ruscogenin (rus), first isolated from ruscus aculeatus, also a major steroidal sapogenin of traditional chinese herb radix ophiopogon japonicus, has been found to exert significant anti-inflammatory and anti-thrombotic activities. our previous studies suggested that ruscogenin remarkably inhibited adhesion of leukocytes to a human umbilical vein endothelial cell line (ecv304) injured by tumor necrosis factor-alpha (tnf-alpha) in a concentration-dependent manner. yet the underlying mechanisms rem ... | 2008 | 18946195 |
| preventive effect of ophiopogon japonicus polysaccharides on an autoallergic mouse model for sjogren's syndrome by regulating the th1/th2 cytokine imbalance. | sjogren's syndrome (ss) is an autoimmune disorder characterized by lymphocytic infiltration of salivary and lacrimal glands leading to xerostomia and keratoconjunctivitis sicca. evidence has accumulated suggesting that a th1/th2 cytokine imbalance has a role in the pathogenesis of ss. currently, only palliative treatment is available. ophiopogon japonicus, a common chinese herbal, has been used to treat sicca-associated disorders in traditional chinese medicine for centuries. | 2007 | 17888600 |
| antithrombotic activities of aqueous extract from radix ophiopogon japonicus and its two constituents. | to provide further pharmacological evidence for its clinical use in thrombotic diseases, the antithrombotic activities of the aqueous extract of radix ophiopogon japonicus (roj-ext) were studied in mouse and rat models. the results showed that roj-ext remarkably decreased length of tail thrombus in mice at 48 h and 72 h after carrageenan injection at doses of 12.5 and 25.0 mg/kg. meanwhile, roj-ext markedly inhibited thrombosis induced by arterial-venous (av) shunt (silk thread) in rats at doses ... | 2006 | 16755031 |
| anti-inflammatory activities of aqueous extract from radix ophiopogon japonicus and its two constituents. | to provide some pharmacological evidence for its clinical use in inflammatory diseases, anti-inflammatory effect of the aqueous extract from radix ophiopogon japonicus (roj-ext), a traditional chinese herb, was examined in mouse and rat models. roj-ext significantly inhibited xylene-induced ear swelling and carrageenan-induced paw edema in mice when given orally at doses of 25 and 50 mg/kg. moreover, roj-ext also remarkably suppressed carrageenan-induced pleural leukocyte migration in rats and z ... | 2005 | 15997105 |
| effects of several chinese herbal aqueous extracts on human sperm motility in vitro. | the effects of six kinds of aqueous extracts of chinese herbal medicine (astragalus membranaceus, acanthopanacis senticosi, panax genseng and ophiopogon japonicus, p. genseng and aconitum carmichaeli, salviae miltiorrhiae, polyporus umbellatus polysaccharide) on sperm motility characteristics of 30 infertile male volunteers were studied in vitro with a computer-assisted sperm analysis at 15, 60 and 180 min after incubated with the drugs. the results showed that per cent viability, number of prog ... | 2004 | 15084153 |
| the ameliorating effects of cognition-enhancing chinese herbs on scopolamine- and mk-801-induced amnesia in rats. | the study was to investigate the ameliorating effects of three chinese herbs--achyranthes bidentata (ab), ophiopogon japonicus (oj) and cnidium monnieri (cm) on scopolamine (scop)- and mk-801-induced amnesia by using a passive avoidance task in rats. ab, oj and cm at 0.1 and 0.3 g/kg prolonged the step-through latency (stl) of the retention trial. in addition, ab, oj and cm reversed the stl shortened by mk-801, but only ab reversed the stl shortened by scop. in conclusion, these chinese herbs po ... | 2003 | 14587877 |
| prevention and repair of cerebral ischemia-reperfusion injury by chinese herbal medicine, shengmai san, in rats. | the protective activity of shengmai san, a traditional chinese herbal medicine, was studied in cerebral ischemia-reperfusion injury in rats. shengmai san consists of three herbal components, panax ginseng, ophiopogon japonicus and schisandra chinensis and is routinely being used for treating coronary heart disease. when shengmai san was injected directly into rat duodenum 2h before cerebral ischemia by bilateral carotid artery occlusion, thiobarbituric acid reactive substance (tbars) formation d ... | 1999 | 10547189 |
| determination of ophiopogon japonicus polysaccharide in plasma by hplc with modified postcolumn fluorescence derivatization. | interest in antimyocardial ischemic activity of a graminan-type fructosan with an average molecular weight of 5,000 da from ophiopogon japonicus (foj-5) has necessitated the development of a sensitive and specific method to study its pharmacokinetics. an hplc method with modified postcolumn fluorescence derivatization to determine foj-5 in plasma was developed in this study. the shodex sugar ks-802 high-performance gel column was chosen for separating foj-5 from its degradation products and endo ... | 2005 | 15935322 |
| effects of sheng-mai injection on the prpp synthetase activity in bfu-es and cfu-es from bone marrows of mice with benzene-induced aplastic anemia. | 160 kunming mice were divided at random into 3 groups. group 1: normal control (40 mice). group 2: aplastic anemia (aa) control (60 mice); benzene inhalation was carried out for 2.5 months and sterilized normal saline was injected i.p. for another 6 weeks. group 3: treated aa (60 mice); benzene was administered by inhalation in a similar manner, sheng-mai injection (smi) was administered i.p. for 6 weeks after the aa models were established. smi is a famous chinese traditional prescription of pa ... | 2001 | 11531161 |
| [effects of danshen and shengmaiye on glomerulosclerosis by adriamycin in rats]. | to investigate the effects of danshen(salvia plectranthoides griff.) and shengmaiye (panax ginseng c. a. mey, ophiopogon japonicus ker-gawl and schisandra chinensis baill) on glomerulosclerosis induced by adriamycin in sd rats. | 1999 | 12080639 |
| fermentation effects of oligosaccharides of radix ophiopogonis on alloxan-induced diabetes in mice. | in this study, oligosaccharides extracted from ophiopogon japonicus vinegar (oov) by alcoholic and acetic acid fermentation with water extracts from radix ophiopogon and oligosaccharides extracted from radix ophiopogonis (ooj) were investigated. characterization of the extracts indicated that oov are proteoglycans, whereas ooj are not. moreover, compared with ooj, monosaccharide compositions of oov only include fructose and galactose and not glucose. maldi-tof-mass spectrometric results showed t ... | 2011 | 21549746 |
| new neuritogenic steroidal saponin from ophiopogon japonicus (thunb.) ker-gawl. | a new steroidal saponin was isolated from ophiopogon japonicus. this saponin possesses a modification by 2-hydroxy-3-methylvalerylation of the hydroxyl group at c-4' of the sugar, linked to c-1 of the aglycone. it exhibited significant neuritogenic activity for pc12 cells. the structure-activity relationship revealed the aglycone, rather than the sugar moieties and acylation, to be important for the neuritogenic activity. | 2011 | 21670508 |
| hypoglycemic effects of mdg-1, a polysaccharide derived from ophiopogon japonicas, in the ob/ob mouse model of type 2 diabetes mellitus. | ophiopogon japonicus is a traditional chinese medicine used to treat diabetes mellitus. we investigate the anti-ischemic properties of a water-soluble ß-d-fructan (mdg-1) from o. japonicus, and assess the antidiabetic effects of mdg-1. in the study, ob/ob mice were treated with 150mg/kg or 300mg/kg mdg-1 by gavage for 23d. blood glucose levels were measured regularly. an oral glucose tolerance test (ogtt) was preformed on day 21. the levels of insulin, total cholesterol and triglyceride in the s ... | 2011 | 21756932 |
| [mitochondrial dysfunction induced by excessive ros/rns-metabolic cardiovascular disease and traditional chinese medicines intervention]. | metabolic cardiovascular disease is a type of disease which almost caused by body carbohydrate and lipid metabolism dysfunction. type 2 diabetes mellitus is a typical metabolic disease. it not only lead to the insulin resistance but also related to atherosclerosis. oxidative stress is produced by the reactive oxygen/nitrogen species (ros/rns). oxidative stress and its consequence events play important roles in atherosclerosis (as). mitochondria are both sources and targets of reactive oxygen and ... | 2011 | 22121816 |
| brain oxidative stress as basic target of antioxidant traditional oriental medicines. | prevention and amelioration of mibyou (sub-healthy condition) is the critical target for disease prevention including age-related diseases and cancer although the mibyou condition is not yet pathologically defined. since the oxidative stress is an underlying basic etiology associated with many diseases and aging, the psychologically induced oxidative stress, especially in the brain was supposed as one of the pathology of mibyou. several traditional herbal prescriptions applied for the brain diso ... | 2009 | 18987970 |
| shengmai san reduces hepatic lipids and lipid peroxidation in rats fed on a high-cholesterol diet. | shengmai san (sms), which is comprised of the medicinal herbs of panax ginseng c.a. meyer, schisandra chinensis baill., and ophiopogon japonicus ker-gawl (2:1:2)., is a traditional chinese medicine being used for treating coronary heart disease. the aim of this study was to investigate the effects of sms on the plasma and liver lipids, lipid peroxidation and antioxidant systems in liver and heart of cholesterol-fed rats. rats were fed on a high-cholesterol (0.5%) diet (control group), high-chole ... | 2008 | 18162350 |
| pharmacokinetic comparisons of schizandrin after oral administration of schizandrin monomer, fructus schisandrae aqueous extract and sheng-mai-san to rats. | sheng-mai-san (sms) is a famous traditional chinese medicine (tcm) recipe, containing radix ginseng (panax ginseng c.a. mey., araliaceae), radix ophiopogonis (ophiopogon japonicus (thunb.) ker-gawl., liliaceae) and fructus schisandrae (schisandra chinensis (turcz.) baill., magnoliaceae), and has been used more than one thousand years. in this research, pharmacokinetics of one component of this tcm recipe was studied. schizandrin is the main absorbed effective ingredient of fructus schisandrae an ... | 2008 | 18060709 |
| a polysaccharides mdg-1 augments survival in the ischemic heart by inducing s1p release and s1p(1) expression. | ophiopogon japonicus is a traditional chinese medicine used to treat cardiovascular disease. recent studies have confirmed the anti-ischemic properties of a water-soluble β-d-fructan (mdg-1) from o. japonicus. the sphingosine 1-phosphate (s1p) signaling pathway is involved in its cytoprotective effects. herein, we explore the role of the s1p signaling pathway in the anti-ischemic effect of mdg-1 and assess one possible mechanism by which it induces s1p release and sphingosine 1-phosphate recepto ... | 2011 | 22197795 |
| antitumor activity of bacterial exopolysaccharides from the endophyte bacillus amyloliquefaciens sp. isolated from ophiopogon japonicus. | the endophytic bacterium, md-b1, was isolated from the medicinal plant ophiopogon japonicas and identified as the bacillus amyloliquefaciens sp. with 99% similarity based on the partial sequence analysis of 16s rdna. exopolysaccharides were extracted from the endophyte for the evaluation of its antitumor activity against gastric carcinoma cell lines (mc-4 and sgc-7901). 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assays and microscopy were performed to estimate the cell vi ... | 2013 | 23833642 |
| determination of ruscogenin in crude chinese medicines and biological samples by immunoassay. | ruscogenin is a major bioactive steroidal aglycone found in the chinese medicine, ophiopogon japonicus. we have developed a quantitative determination of ruscogenin with an indirect enzyme-linked immunosorbent (elisa) assay using polyclonal antibodies against ruscogenin conjugated with bovine serum albumin. this assay was highly sensitive, and it had considerably less cross-reactivity to diosgenin and sarsasapogenin, but high cross-reactivity to ruscogenin glycosides. the assay was successfully ... | 2006 | 16957914 |
| release-controlling absorption enhancement of enterally administered ophiopogon japonicus polysaccharide by sodium caprate in rats. | the aim of this study was to improve the intestinal absorption of ophiopogon japonicus polysaccharide (ojp) by incorporating it together with sodium caprate (sc) into erodible matrices, designed to release ojp and sc at various rates over different periods of time. ojp, a graminan type fructosan with an average molecular weight in number of 3400 da has been demonstrated to have anti-myocardial ischemic activity. the determination of ojp blood levels was carried out by the fluorescein isothiocyan ... | 2006 | 16937339 |
| antimicrobial activities of endophytic fungi isolated from ophiopogon japonicus (liliaceae). | drug resistance in bacteria has become a global concern and the search for new antibacterial agents is urgent and ongoing. endophytes provide an abundant reservoir of bioactive metabolites for medicinal exploitation, and an increasing number of novel compounds are being isolated from endophytic fungi. ophiopogon japonicus, containing compounds with antibacterial activity, is a traditional chinese medicinal plant used for eliminating phlegm, relieving coughs, latent heat in the lungs, and allevia ... | 2012 | 23190550 |
| multiple mechanism confers natural tolerance of three lilyturf species to glyphosate. | a combination of unique epsps structure and increased gene copy number and expression contribute to natural glyphosate tolerance in three lilyturf species. a few plants are naturally tolerant to glyphosate, the most widely used non-selective herbicide worldwide. here, the basis for natural tolerance to glyphosate in three lilyturf species, ophiopogon japonicus (oj), liriope spicata (ls), and liriope platyphylla (lp), is characterized. these species tolerate glyphosate at about five times the com ... | 2016 | 26411727 |
| role of component herbs in antioxidant activity of shengmai san--a traditional chinese medicine formula preventing cerebral oxidative damage in rat. | traditional chinese medicine (tcm) is an attractive model for studying antioxidant-based composite therapy. we previously reported that shengmai san (sms), a tcm formulation for treating cardiac disorders, inhibited cerebral oxidative damage in rats when evaluated by both glutathione peroxidase (gpx) activity loss and thiobarbituric acid reactive substance (tbars) formation after forebrain ischemia-reperfusion. in the present study, we further examined the preventive effect of sms and related de ... | 2003 | 14587874 |
| inhibitory effects of ethanol extract from radix ophiopogon japonicus on venous thrombosis linked with its endothelium-protective and anti-adhesive activities. | the in-vivo inhibitory effects of the ethanol extract of radix ophiopogon japonicus (roj-ext) on venous thrombosis were studied in mouse and rat models and in-vitro endothelial cell-protective and anti-adhesive activities were observed in ecv304 cells injured by sodium dithionite and hl-60 adhesion to ecv304 cells injured by tnf-alpha. the in-vivo results showed that roj-ext significantly inhibited venous thrombosis induced by tight ligation of the inferior vena cava for 6 h in mice and for 24 h ... | 2005 | 16054441 |
| pseudoclavibacter terrae sp. nov. isolated from rhizosphere soil of ophiopogon japonicus. | strain thg-md12t, a gram-reaction-positive, aerobic, non-motile, rod-shaped bacterium was isolated from rhizosphere soil of ophiopogon japonicus in pr china. thg-md12t was closely related to members of the genus pseudoclavibacter and showed the highest 16s rrna gene sequence similarities with pseudoclavibacter helvolus kctc 19531t (98.8 %) and pseudoclavibacter chungangensis kctc 22691t (96.9 %). dna-dna hybridization showed 41.9 ± 2.1 % and 12.4 ± 0.9 % dna reassociation with p. helvolus kctc 1 ... | 2015 | 26311346 |
| ophiopogonin d prevents h2o2-induced injury in primary human umbilical vein endothelial cells. | vessel endothelium injury caused by reactive oxygen species (ros) including h(2)o(2) plays a critical role in the pathogenesis of cardiovascular disorders. therefore, drug targeting ros elimination has highly clinical values in cardiovascular therapy. the plant of radix ophiopogon japonicus is a traditional chinese herbal medicine that has been commonly used for prevention and treatment of cardiovascular diseases for a long history. however, the effective component mediating its beneficial effec ... | 2010 | 20083185 |
| ophiopojaponin d, a new phenylpropanoid glycoside from ophiopogon japonicus ker-gawl. | a new phenolic glycoside, ophiopojaponin d (1), together with two known compounds, was isolated from the tubers of a famous traditional chinese herb-ophiopogon japonicus ker-gawl. the spectroscopic and chemical data revealed their structures to be 3-tetradecyloxy-4-hydroxy-allylbenzene-4-o-alpha-l-rhamnopyranosyl (1-->6)-beta-d-glucopyranoside (1), 3, 4-dihydroxy-allylbenzene-4-o-alpha-l-rhamnopyranosyl (1-->6)-beta-d-glucopyranoside (2) and l-pyroglutamic acid (3). | 2005 | 16350848 |
| [analysis on urban vegetations reflectance characteristics in shanghai]. | the spectral features of ground objects are not only the brief contents of mechanism of remote sensing, but also the important basis in remote sensing application. as one of main components of terrestrial ecosystems, urban forest plays a key role in maintaining urban ecosystem balance. in the present paper, the authors adopted fieldspec 3 portable spectroscope made by american asd company, and investigated or examined some spots in the kangjian park of shanghai, china. the spectra of euonymus ja ... | 2010 | 21284194 |
| [comprehensive comparison between erective and creepy ophiopogon japonicus of sichuan]. | to compare the agronomic characters, hplc fingerprints, the content of main component and amino acid between erective and creepy ophiopogon japonicus of sichuan. | 2009 | 20067010 |
| identification of novel pregnane x receptor activators from traditional chinese medicines. | to investigate the ability of traditional chinese medicines (tcms) and their bioactive compounds to activate pregnane x receptor (pxr) signalling pathway. | 2011 | 21524698 |
| phyllosticta ophiopogonis sp. nov. from ophiopogon japonicus (liliaceae). | a leaf spotting disease of an ornamental variety of ophiopogon japonicus was discovered at several locations in northern thailand. in all cases a species of phyllosticta was associated with the lesions. phyllosticta ophiopogonis sp. nov. is distinguished from phyllosticta species from liliaceae in conidia size, mucilaginous sheath and appendage thus the species is introduced as new in this paper. the new species which causes unsightly lesions on this ornamental plant is described, illustrated an ... | 2012 | 23961156 |
| [kinetic model for extraction process of chinese traditional medicine]. | to present a theory bases for chinese traditional medicine extraction process. | 2002 | 12914329 |
| post-hematopoietic stem cell transplantation in patients with hematologic disorders: chinese herbal medicine for an unmet need. | while much progress has been made in the field of hematopoietic stem cell transplantation (hsct), headway in the promotion of recovery following this procedure has been limited. data regarding the potential of chinese herbal medicine (chm) for patients with hematologic disorders who received hsct are gradually increasing; however, these data are mostly in chinese. therefore, we set out to summarize the existing data. we searched pubmed, the cochrane library and the china national knowledge infra ... | 2016 | 27641605 |
| a steroidal saponin from ophiopogon japonicus extends the lifespan of yeast via the pathway involved in sod and uth1. | nolinospiroside f is a steroidal saponin isolated from ophiopogon japonicus (o. japonicus). in this study, we found that nolinospiroside f significantly extends the replicative lifespan of k6001 yeast at doses of 1, 3 and 10 μm, indicating that it has an anti-aging effect. this may be attributed to its anti-oxidative effect, as nolinospiroside f could increase yeast survival under oxidative stress conditions and decrease the level of malondialdehyde (mda), an oxidative stress biomarker. it could ... | 2013 | 23439553 |
| isolation of actinomycetes from the root of the plant, ophiopogon japonicus, and proposal of two new species, actinoallomurus liliacearum sp. nov. and actinoallomurus vinaceus sp. nov. | actinomycete strains k10-0485(t) and k10-0528(t) were isolated from the roots of ophiopogon japonicus collected in yokohama, kanagawa prefecture, japan. the 16s ribosomal rna (rrna) gene sequences, morphological characteristics and chemotaxonomic data indicated that these strains belonged to the genus actinoallomurus. strain k10-0485(t) showed high similarity of the 16s rrna gene sequence with a. luridus tt02-15(t) (99.1%), but the dna-dna hybridization relatedness values between strain k10-0485 ... | 2012 | 22511226 |
| polygonatum cyrtonema lectin induces murine fibrosarcoma l929 cell apoptosis via a caspase-dependent pathway as compared to ophiopogon japonicus lectin. | galanthus nivalis agglutinin (gna)-related lectin family, a superfamily of strictly mannose-binding specific lectins, has been well-known to possess several biological functions including apoptosis-inducing activities. however, the precise mechanisms of gna-related lectins to induce apoptosis remains to be clarified. in this study, we showed that polygonatum cyrtonema lectin (pcl) and ophiopogon japonicus lectin (ojl), the two mannose-binding gna-related lectins, could induce murine fibrosarcoma ... | 2010 | 20655713 |