| fenbendazole for treatment of paragonimus kellicotti infection in dogs. | the effect of fenbendazole therapy was studied in 9 dogs with pulmonary paragonimiasis induced by inoculation of metacercariae (25/dog) of paragonimus kellicotti. at 42 to 47 days after 6 dogs were inoculated, they were given fenbendazole in 2 divided doses totaling 50 mg (4 dogs) or 100 mg (2 dogs)/kg of body weight each day for 10 to 14 days. three dogs were not treated. the passage of paragonimus eggs in the feces ceased after 3 days at the high dosage and after 3 to 8 days at the low dosage. ... | 1979 | 500425 |
| albendazole therapy for experimentally induced paragonimus kellicotti infection in cats. | the effect of albendazole therapy was studied in 6 cats with pulmonary paragonimiasis induced by experimental inoculation of metacercariae (25/cat) of paragonimus kellicotti. at 76 to 101 days after they were inoculated, 5 cats were administered an oral aqueous suspension of albendazole in 2 divided doses totaling 20 mg (2 cats), 50 mg (1 cat), or 100 mg (2 cats)/kg of body weight each day for 14 to 21 days. the 6th cat (control) was not administered albendazole. nine days after cats were given ... | 1978 | 666077 |
| induced paragonimiasis in cats: clinical signs and diagnosis. | twenty-eight specific-pathogen-free cats were inoculated with 14 to 50 metacercariae of paragonimus kellicotti obtained from the hearts of naturally infected crayfish. young flukes excysted in the intestine of cats and appeared in the peritoneal cavity from 1 to 14 days after inoculation (dai) and in the pleural cavity from 5 to 23 dai. flukes penetrated the pulmonary parenchyma and formed hemorrhagic subpleural lesions within 5 weeks after inoculation. marked eosinophilia developed between 2 an ... | 1978 | 711593 |
| the life cycle of paragonimus kellicotti in cats. | migration and development of paragonimus kellicotti were studied in cats killed between 1 and 265 days after feeding 15--20 metacercariae from the hearts of naturally infected crayfish. metacercariae excysted in the intestine and appeared in the peritoneal cavity within 24 hr. some young flukes penetrated the diaphragm and migrated to the pleural cavity during the first week, but the majority penetrated the pleura between 10 and 14 days. no flukes were found in the pleural cavity after 23 days p ... | 1978 | 739320 |
| viruslike inclusions in the cecal epithelial cells of pa agonimus kellicotti (digenea, troglotrematidae). | rodlike or tubular inclusions are described from the cytoplasm and nuclear matrix of the cecal epithelial cells of paragonimus kellicotti. these inclusions are 3.4 mu or more long, 350 a in diameter, and comprised of a wall of helically arranged subunits and a dense, possibly filar, central core. they occur in organized bundles of up to 17 members. cells containing these inclusions manifest a series of nucleolar modifications typical of inclusions is discussed, noting especially their resemblanc ... | 1975 | 1127553 |
| paragonimus kellicotti infection in wild carnivores in southwestern ontario: ii. histopathologic features. | pulmonary lesions associated with naturally acquired paragonimus kellicotti infection were studied in mink (mustela vison), striped skunks (mephitis mephitis), red foxes (vulpes vulpes) and a coyote (canis latrans). in ,ink a fibrous capsule was formed around mature flukes in dilated bronchioles or bronchi, and there was mild focal interstitial pneumonitis adjacent to fluke eggs in alveoli and migrating parasites. a thick wall, infiltrated heavily with mononuclear cells and eosinophils, surroun ... | 1975 | 1152176 |
| mortality in syrian hamsters infected with paragonimus kellicotti. | in an attempt to find a small animal model for paragonimiasis, syrian hamsters were infected with between 1 and 16 metacercariae of paragonimus kellicotti. a definitive mortality dose-response was observed with 90% of all hamsters given 3 or more parasites succumbing to the infection within 35 days. hamsters demonstrated acute pleuritis, reactive mesothelial hyperplasia, subpleural accumulations of reactive and mature plasma cells, neovascularization, fibrohistiocytic thickening with and without ... | 1992 | 1556655 |
| evaluation of praziquantel for treatment of experimentally induced paragonimiasis in dogs and cats. | praziquantel was used successfully for treatment of a small number of dogs and 1 cat infected with paragonimus kellicotti. to further evaluate the usefulness of this drug in treating such infections, 7 cats and 7 dogs were inoculated orally with metacercariae (12 and 20 to 22, respectively) obtained from crayfish, then were treated after the infections became patent; 2 cats and 2 dogs served as noninfected controls. beginning 1 week before infection, and continuing weekly thereafter, physical, h ... | 1991 | 1826991 |
| lesions associated with pulmonary parasites in bobcats (felis rufus) from arkansas. | two of five bobcats (felis rufus) from southwestern arkansas had natural pulmonary infections of paragonimus kellicotti and filaroides rostratus. pairs of p. kellicotti were found in spherical cyst-like structures approximately 1 cm in diameter. filaroides rostratus were seen as serpentine pale white areas on the pleural surface and also firmly embedded in fibrous capsules in the pulmonary parenchyma. histologic lesions associated with the presence of these parasites consisted primarily of a ver ... | 1991 | 2023320 |
| the american lung fluke, paragonimus kellicotti, in a cat model. | twenty-four specific-pathogen-free domestic cats were infected orally with from 2 to 30 paragonimus kellicotti metacercariae and followed for 2-61 wk. following infection by metacercarial cysts dissected from crayfish, the lungs of the cats undergo changes of intense eosinophilic pneumonia, granulomatous pneumonitis, squamous epithelial-lined cyst formation of bronchogenic origin, and finally (late in infection) partial resolution of the host response. bronchograms and mechanical probing illustr ... | 1990 | 2143226 |
| a human infection with paragonimus kellicotti (lung fluke) in the united states. | a first case of paragonimus kellicotti infection, in the united states, involving a nonimmigrant adult, is reported. diagnosis was made on sputum cell block sections and demonstration of the characteristic operculated ova of the parasite by direct sputum smear preparation. the patient had never been outside the united states. he responded favorably to praziquantel and was asymptomatic after therapy. | 1986 | 3776924 |
| factors in developmental delay of paragonimus kellicotti miracidia. | | 1986 | 3806328 |
| paragonimiasis in a dog: treatment with praziquantel. | oral administration of 25 mg of praziquantel/kg of body weight 3 times a day for 2 consecutive days resulted in clinical and parasitologic cure of paragonimiasis in a dog. previous treatment with the drug at the dosage recommended for cestode removal (5 mg/kg, sc) for 2 days was only partially effective. the dog exhibited cachexia, coughing, gagging, and occasional hemoptysis. radiography revealed nodular and cystic densities in the lungs. the life history and clinical aspects of paragonimus kel ... | 1985 | 4019305 |
| paragonimus kellicotti (ward, 1908) in a minnesota skunk (melphitis mephitis). | | 1971 | 5167765 |
| comparative study of the mexican lung flukes with paragonimus kellicotti ward, 1908. | | 1968 | 5757671 |
| differential morphology of paragonimus kellicotti in north america. | | 1966 | 5951302 |
| anthelmintic effect of febantel/praziquantel paste in dogs and cats. | a paste formulation of 3.4% febantel and 0.34% praziquantel was given in soft food at a rate of 0.29 g/kg of body weight, once daily for 3 days to dogs and cats. eleven of 12 dogs were naturally infected with ancylostoma caninum, 10 with trichuris vulpis, 2 with toxocara canis, 5 with taenia sp, and 3 with dirofilaria immitis. ten of 11 cats were naturally infected with toxocara cati, 2 with ancylostoma tubaeforme, 3 with taenia sp, 5 with capillaria aerophila, and 1 with paragonimus kellicotti. ... | 1984 | 6703448 |
| endoparasites and selected infectious agents in bobcats (felis rufus) from west virginia and georgia. | a total of 143 bobcats (felis rufus) from west virginia and 10 bobcats from georgia was examined for parasites and selected infectious agents. a total of 31 species of parasites was recovered including 1 protozoan, 1 trematode, 4 cestodes, 1 acanthocephalan and 24 nematodes. results indicate bobcats are important definitive hosts for sarcocystis sp. and toxoplasma gondii. thirteen species (paragonimus kellicotti, spirometra mansonoides, taenia macrocystis, t. rileyi, capillaria putorii, toxascar ... | 1981 | 6802988 |
| albendazole for treatment of paragonimus kellicotti infection in two cats. | | 1981 | 7240006 |
| observations on paragonimus kellicotti ward from georgia. | | 1958 | 13550027 |
| development of the mother sporocyst and rediae of paragonimus kellicotti ward, 1908. | | 1951 | 14861725 |
| human paragonimiasis in north america following ingestion of raw crayfish. | paragonimiasis (human infections with the lung fluke paragonimus westermani) is an important public health problem in parts of southeast asia and china. paragonamiasis has rarely been reported from north america as a zoonosis caused by paragonimus kellicotti. paragonimus species have complex life cycles that require 2 intermediate hosts, namely, snails and crustaceans (ie, crabs or crayfish). humans acquire p. kellicotti when they consume infected raw crayfish. humans with paragonimiasis usually ... | 2009 | 19681705 |
| human paragonimiasis after eating raw or undercooked crayfish --- missouri, july 2006-september 2010. | paragonimiasis is a parasitic disease caused by paragonimus trematodes, commonly known as lung flukes. humans become infected by eating raw or undercooked crayfish (also known as crawfish and crawdads) or freshwater crabs that harbor the parasites. paragonimiasis most frequently involves the lungs, but can affect other organs, including the brain and skin. in north america, paragonimus kellicotti causes infections among dogs, cats, and wild carnivores, but rarely infects humans. paragonimiasis i ... | 2010 | 21150864 |
| molecular characterization of the north american lung fluke paragonimus kellicotti in missouri and its development in mongolian gerbils. | abstract. human paragonimiasis is an emerging disease in missouri. to characterize local parasites, we examined crayfish from three rivers. metacercaeriae consistent with paragonimus kellicotti were detected in 69%, 67%, and 37% of crayfish from the big piney, huzzah, and black rivers, respectively. sequencing of the second internal transcribed spacer and other dna markers confirmed the species identification and the presence of identical parasite sequences in clinical specimens from two human c ... | 2011 | 21633042 |
| what is your diagnosis? paragonimus kellicotti infection. | | 2010 | 20919841 |
| north american paragonimiasis (caused by paragonimus kellicotti) in the context of global paragonimiasis. | paragonimus species are highly evolved parasites with a complex life cycle that involves at least three different hosts, i.e., snails, crustaceans, and mammals. the adult forms of paragonimus species reside and mate in the lungs of a variety of permissive mammalian hosts, including humans. although human paragonimiasis is uncommonly encountered in north america, both autochthonous and imported disease may be encountered. paragonimus kellicotti, the species endemic to north america, is a well-kno ... | 2009 | 19597007 |
| autochthonous human paragonimiasis in north america. | imported human paragonimiasis has been reported in the united states. however, autochthonous cases are rare. we describe a case of probable paragonimus kellicotti infection associated with ingestion of crayfish and review all autochthonous cases in this country. | 2007 | 17896846 |
| effects of bithionol against paragonimus kellicotti in rats. | | 1964 | 14196057 |
| cavitary mass lesion and recurrent pneumothoraces due to paragonimus kellicotti infection: north american paragonimiasis. | north american paragonimiasis is well described in omnivorous and carnivorous animals on this continent. humans are rarely infected, largely because of dietary customs, but are at risk for infection if raw or undercooked crayfish are consumed. we describe a patient with a pleuropulmonary infection due to paragonimus kellicotti that presented as recurrent pneumothoraces and a cavitary lesion. this is the first case of north american paragonimiasis in which the diagnosis was based on the morpholog ... | 2003 | 12883250 |
| north american paragonimiasis: case report of a severe clinical infection. | paragonimiasis is an important cause of pulmonary disease worldwide. it results from an infection with paragonimus, a parasite that reproduces through a complex life cycle involving snails, crustaceans, and mammals. humans acquire the disease by ingesting uncooked freshwater crab or crayfish. paragonimus species are distributed globally, and the disease is well known in endemic regions of asia where culturally based methods of food preparation foster human transmission. paragonimus also exists i ... | 2002 | 11948081 |
| north american paragonimiasis. a case report. | paragonimiasis is a parasitic infection with a predilection for pulmonary involvement. paragonimus species occur throughout the world and exist in nature in a snail-crustacean-mammalian life cycle. human disease is most frequently encountered in cultures that ingest raw or undercooked crustaceans. north american paragonimiasis, caused by an endemic paragonimus species, paragonimus kellicotti, predominantly causes disease in carnivorous and omnivorous animals but may cause human disease if the in ... | 2000 | 10667165 |
| sudden death due to paragonimus kellicotti infection in a dog. | a sudden death due to paragonimus kellicotti infection in a dog that had had no previous clinical signs of illness until the day of admission to the veterinary hospital is documented. the clinical, haematological and biochemical abnormalities, as well as postmortem findings, are presented. this report represents the first case of canine paragonimiasis in israel, and discusses the possibility of this fluke becoming established in the middle east. | 1997 | 9231989 |
| feline respiratory tract disease in louisiana. | an investigation of feline respiratory tract disease (frd) was made involving 65 affected cats (group 1) and 65 control cats (group 2) matched for age, sex, and residence. feline calicivirus strains (fcv), feline herpesvirus-1 (fhv-1), or both, were isolated from 59% of group 1 cats and from 7% of group 2 cats. isolation of these viruses showed a significantly greater (p < 0.05) relative risk for group 1 cats. virus isolations were three times more frequent from males than from females older tha ... | 1980 | 6255833 |
| helminths of the raccoon (procyon lotor) in western kentucky. | seventy raccoons (procyon lotor) from western kentucky were examined for helminths from december 1985 through may 1986. twenty-three species of helminths were collected including 10 species of trematoda (brachylaima virginiana, euryhelmis squamula, eurytrema procyonis, fibricola cratera, gyrosoma singulare, maritreminoides nettae, mesostephanus appendiculatoides, metagonimoides oregonensis, paragonimus kellicotti, pharyngostomoides procyonis), 2 species of cestoda (atriotaenia procyonis, mesoces ... | 1987 | 3625429 |
| diseases diagnosed in gray foxes (urocyon cinereoargenteus) from the southeastern united states. | diagnostic findings were reviewed on 157 sick or dead gray foxes (urocyon cinereoargenteus) from the southeastern united states examined during the period 1972 through 1989. most foxes (n = 118) originated from georgia; fewer animals were from florida, kentucky, maryland, mississippi, north carolina, south carolina, tennessee, virginia and west virginia. etiologic diagnoses included canine distemper (n = 125), congenital absence of guard hairs (n = 7), traumatic injuries (n = 7), rabies (n = 3), ... | 1992 | 1548799 |
| paragonimus kellicotti infection in wild carnivores in southwestern ontario: i. prevalence and gross pathologic features. | paragonimus kellicotti ward, 1908 was recovered from 16 of 105 mink (mustela vison), 14 of 244 striped skunks (mephitis mephitis), 10 of 446 red foxes (vulpes vulpes), 1 of 31 coyotes (canis latrans), 0 of 326 raccoons (procyon lotor) and 0 of 8 weasels (mustela spp.) collected from southwestern ontario. the majority of carnivores harboring p. kellicotti was collected from two counties (huron and bruce) bordering the east shore of lake huron where 6.0% of the animals (excluding raccoons) were in ... | 1975 | 1113433 |
| ova of the lung fluke paragonimus kellicotti in fluid from a cyst. | | 1975 | 1056681 |
| pathogenesis of experimental pulmonary paragonimiasis in cats. | specific-pathogen-free cats (n = 20) were inoculated orally with metacercariae of paragonimus kellicotti and necropsied between 1 and 263 days later. the immature paragonimus flukes excysted in the intestine, penetrated the intestinal wall, and migrated from the peritoneal cavity through the diaphragm to the pleural surface of lungs by postinoculation days (pid) 5 to 23. this migration resulted in multifocal eosinophilic peritonitis and myositis. the flukes entered the lung by penetration of the ... | 1978 | 736340 |
| paragonimus kellicotti flukes in missouri, usa. | paragonimiasis is an infection caused by lung flukes of the genus paragonimus. in asia, p. westermani infections are relatively common because of dietary practices. however, in north america, cases of paragonimiasis, which are caused by p. kellicotti flukes, are rare. only 7 autochthonous cases of paragonimiasis were reported during 1968-2008. in 2009, we reported 3 new case-patients with paragonimiasis who had been seen at our medical center over an 18-month period. six additional case-patients ... | 2012 | 22840191 |
| serological diagnosis of north american paragonimiasis by western blot using paragonimus kellicotti adult worm antigen. | abstract. we studied the value of an igg western blot (wb) with paragonimus kellicotti (pk) antigen for diagnosis of north american paragonimiasis. the test was evaluated with sera from patients with pk and paragonimus westermani infections, with control sera from patients with other helminth infections, and sera from healthy americans. all 11 proven pk infection sera and two samples from suspected cases that were negative by p. westermani wb at the centers for disease control and prevention (cd ... | 2013 | 23589531 |
| paragonimiasis acquired in the united states: native and nonnative species. | paragonimiasis is a parasitic lung infection caused by lung flukes of the genus paragonimus, with most cases reported from asia and caused by p. westermani following consumption of raw or undercooked crustaceans. with the exception of imported p. westermani cases in immigrants, in travelers returning from areas of disease endemicity, and in clusters of acquired cases following consumption of imported asian crabs, human paragonimiasis caused by native lung flukes is rarely described in the united ... | 2013 | 23824370 |
| paragonimosis in a cat and the temporal progression of pulmonary radiographic lesions following treatment. | a 16 mo old cat presented with a 5 mo history of dyspnea, coughing, and gagging. radiographic findings revealed seven nodules measuring 1-3 cm distributed multifocally in the lungs. examination of feces revealed large numbers of eggs of paragonimus kellicotti. two fenbendazole treatment regimens (28 mg/kg per os q 12 hr for 21 days) and prednisone were required to eliminate the infection. resolution of pulmonary nodules was monitored for 8 mo following successful treatment, and four lesions were ... | 2016 | 25028442 |
| systems biology studies of adult paragonimus lung flukes facilitate the identification of immunodominant parasite antigens. | paragonimiasis is a food-borne trematode infection acquired by eating raw or undercooked crustaceans. it is a major public health problem in the far east, but it also occurs in south asia, africa, and in the americas. paragonimus worms cause chronic lung disease with cough, fever and hemoptysis that can be confused with tuberculosis or other non-parasitic diseases. treatment is straightforward, but diagnosis is often delayed due to a lack of reliable parasitological or serodiagnostic tests. henc ... | 2014 | 25329661 |
| north american paragonimiasis: epidemiology and diagnostic strategies. | paragonimiasis is a zoonotic, food-borne trematode infection that affects around 23 million people in asia, africa and the americas. north american paragonimiasis, caused by paragonimus kellicotti, is a common infection of crustacean-feeding mammals in parts of the usa and canada. although infection rates in crayfish are very high in some areas, human infections are rare and depend on the consumption of raw or undercooked crayfish. human infections can be easily prevented and treated, but proper ... | 2015 | 25835312 |
| paragonimus kellicotti: a lung infection in our own backyard. | paragonimiasis is an infection caused by the lung fluke of the genus paragonimus. within the united states, paragonimiasis has been commonly diagnosed in southeast asian immigrants infected with the asian lung fluke paragonimus westermani. infections from the north american lung fluke, paragonimus kellicotti, have been rare, although more infections have been seen in people in the midwestern united states. a 29-year-old male with a history of pleomorphic xanthoastrocytoma presented with hemoptys ... | 2016 | 27213066 |
| paragonimus kellicotti presenting with hemoptysis and a left upper lobe mass. | a 46-year-old man presented to the thoracic surgery clinic with a 6-month history of cough and hemoptysis refractory to treatment. examination of specimens from repeated biopsies was nondiagnostic, so the patient underwent video-assisted thoracoscopic left upper lobe wedge resection. pathologic examination revealed paragonimus organisms, and the patient was prescribed praziquantel, with resolution of his symptoms. although paragonimus infections are common in asia, they are rare in the united st ... | 2016 | 27772589 |
| eosinophilic meningitis due to infection with paragonimus kellicotti. | | 2017 | 28158416 |
| epizootic and zoonotic helminths of the bobcat (lynx rufus) in illinois and a comparison of its helminth component communities across the american midwest. | a total of 6257 helminths of 19 taxa were recovered from the digestive tract and lungs of 67 bobcats in illinois. infections caused by alaria mustelae, diphyllobothrium latum, and macracanthorhynchus ingens are reported for the first time in bobcats. from all the taxa recovered, only three species occurred in high prevalence and caused intense infections: taenia rileyi, alaria marcianae, and toxocara cati, with prevalence and mean intensity of 70% and 6; 42% and 193, and 25% and 14 individuals, ... | 2014 | 24521984 |
| chest ct features of north american paragonimiasis. | the purpose of this study was to characterize the chest ct findings of north american paragonimiasis due to paragonimus kellicotti in the largest (to our knowledge) case series reported to date and to compare the findings with those reported for paragonimiasis infections in other regions. | 2012 | 22528896 |