| toxicological and toxicogenetic effects of plants used in popular medicine and in cattle food. | toxicological and toxicogenetic effects of aqueous (tea) and hexanic fruit extract of indigofera suffruticosa mill. and hydroalcoholic root extract of solanum agrarium stendt. were evaluated in balb c male mice intraperitoneally exposed. a hepatotoxic effect was observed just for animals treated with aqueous fruit extract of i. suffruticosa. in relation to the toxicogenetic effect, just the group treated with 12.5% of toxic dose of aqueous fruit extract of i. suffruticosa showed a statistically ... | 1991 | 1842020 |
| embryotoxicity in vitro with extract of indigofera suffruticosa leaves. | aqueous extract of leaves of indigofera suffruticosa (aelis) were studied for adverse effects in preimplantation mouse embryos. two-cell mouse embryos were cultured for 94 h in human tubal fluid medium (htf), and aelis at a concentration of 5 or 10 mg/ml. on day 4 of culture, morulae and blastocysts were collected for morphological analysis of blastomeres. we found that embryos exposed to the higher concentration of aelis (10 mg/ml) did not develop and all embryos persisted at the two-cell stage ... | 2004 | 15219632 |
| antimicrobial activity of indigofera suffruticosa. | various organic and aqueous extracts of leaves of indigofera suffruticosa mill (fabaceae) obtained by infusion and maceration were screened for their antibacterial and antifungal activities. the extracts were tested against 5 different species of human pathogenic bacteria and 17 fungal strains by the agar-solid diffusion method. most of the extracts were devoid of antifungal and antibacterial activities, except the aqueous extract of leaves of i. suffruticosa obtained by infusion, which showed s ... | 2006 | 16786057 |
| indigofera suffruticosa: an alternative anticancer therapy. | indigofera suffruticosa mill (fabeceae) occurs in the northeast countryside and has intensive popular use in the treatment of infectious, inflammatory and other processes. the main aim of the present work was to investigate the cytotoxic and antitumor effects of aqueous extracts of leaves of i. suffruticosa obtained by infusion and maceration as well as to evaluate the toxicological properties. aqueous extracts did not exhibit cytotoxicity against hep-2 (human epidermoid cancer cell) cell lines ... | 2007 | 17965767 |
| antimycobacterial activity of indigofera suffruticosa with activation potential of the innate immune system. | mycobacterium tuberculosis is responsible for over 8 million cases of tuberculosis (tb) annually. natural products may play important roles in the chemotherapy of tb. the antimycobacterial activity and the innate immune response of methanol (meth) and dichloromethane (dcm) extracts of indigofera suffruticosa miller (fabaceae) were evaluated. we observed that the minimum inhibitory concentrations (mics) for meth and dcm extracts were 125 and 1000 microg/ml, respectively. however, they were able t ... | 2010 | 20673174 |
| experimental poisoning of guinea pig (cavia porcellus) with indigofera suffruticosa. | indigofera suffruticosa causes hemolytic anemia and hemoglobinuria in cattle. the plant was administered to six groups of two guinea pigs each, at the daily dose of 10-ág/kg body weight, for periods of 2, 4, 6, 8, 10 and 15 days. the guinea pigs progressively developed reduced hematocrits and hemoglobin concentrations, and finally presented anemia, without hemoglobinuria. urine passed by guinea pigs that had ingested the plant for more than 24-áh acquired a turquoise blue pigmentation 8-10-áh af ... | 2011 | 21396390 |
| indigofera suffruticosa mill as new source of healing agent: involvement of prostaglandin and mucus and heat shock proteins. | ethnopharmacological relevance: indigofera suffruticosa is specie typical of the "cerrado" or brazilian savannah; it is a member of the fabaceae family - in folkmedicine is used for gastric disorders, infection and inflammation. aim of the study: ethyl acetate fraction (acf) and aqueous fraction (aqf) of the methanolic extract of i. suffruticosa leaves were evaluated against acute gastric ulcer. the acf fraction was selected to assess its activity in ulcer healing and its gastroprotective effect ... | 2011 | 21600972 |
| antibacterial activity of endophytic fungi from leaves of indigofera suffruticosa miller (fabaceae). | endophytic fungi were isolated from healthy leaves of indigofera suffruticosa miller, a medicinal plant found in brazil which is used in folk medicine to treat various diseases. among 65 endophytic fungi isolated, 18 fungi showed activity against at least one tested microorganism in preliminary screening, and the best results were obtained with nigrospora sphaerica (urm-6060) and pestalotiopsis maculans (urm-6061). after fermentation in liquid media and in semisolid media, only n. sphaerica demo ... | 2015 | 25999918 |
| organic extracts from indigofera suffruticosa leaves have antimicrobial and synergic actions with erythromycin against staphylococcus aureus. | a characteristic feature of staphylococcus aureus is its ability to acquire resistance to antimicrobial agents. there is a need, therefore, for new approaches to combat this pathogen; for example, employing a combination of plant-derived products and antibiotics to overcome bacterial resistance. indigofera suffruticosa is a plant popularly used to treat infections and has verified antimicrobial action. here, we investigate the antimicrobial activity of different extracts from i. suffruticosa aga ... | 2015 | 25699022 |
| diazotrophic burkholderia species isolated from the amazon region exhibit phenotypical, functional and genetic diversity. | forty-eight burkholderia isolates from different land use systems in the amazon region were compared to type strains of burkholderia species for phenotypic and functional characteristics that can be used to promote plant growth. most of these isolates (n=46) were obtained by using siratro (macroptilium atropurpureum - 44) and common bean (phaseolus vulgaris - 2) as the trap plant species; two isolates were obtained from nodules collected in the field from indigofera suffruticosa and pithecellobi ... | 2012 | 22609342 |
| oviposition and embryotoxicity of indigofera suffruticosa on early development of aedes aegypti (diptera: culicidae). | aqueous extract of indigofera suffruticosa leaves obtained by infusion was used to evaluate the oviposition, its effect on development of eggs and larvae, and morphological changes in larvae of aedes aegypti. the bioassays were carried out with aqueous extract in different concentrations on eggs, larvae, and female mosquitoes, and the morphological changes were observed in midgut of larvae. the extract showed repellent activity on a. aegypti mosquitoes, reducing significantly the egg laying by f ... | 2011 | 21822443 |
| immunostimulatory and cytotoxic activities of indigofera suffruticosa (fabaceae). | one of the major disadvantages of the current cancer therapy is the suppression of the immune system. brazilian flora is considered one of the most diverse in the world and many plants were found to contain active constituents that can be valuable sources of new drugs. the plant indigofera suffruticosa was studied to determine its potential to stimulate the immune system and also to be effective against tumour cells. we investigated the effects of the alkaloidal fraction and the pure alkaloid in ... | 2011 | 21656418 |