| sox9 gene regulation and the loss of the xy/xx sex-determining mechanism in the mole vole ellobius lutescens. | in most mammals, the y chromosomal sry gene initiates testis formation within the bipotential gonad, resulting in male development. sry is a transcription factor and together with sf1 it directly up-regulates the expression of the pivotal sex-determining gene sox9 via a 1.3-kb cis-regulatory element (tesco) which contains an evolutionarily conserved region (ecr) of 180 bp. remarkably, several rodent species appear to determine sex in the absence of sry and a y chromosome, including the mole vole ... | 2012 | 22215485 |
| echinococcus multilocularis in kyrgyzstan: similarity in the asian emsb genotypic profiles from village populations of eastern mole voles (ellobius tancrei) and dogs in the alay valley. | echinococcus multilocularis is a cestode that causes human alveolar echinococcosis, a lethal zoonosis of public health concern in central asia and western china. in the present study, one of 42 eastern mole voles (ellobius tancrei) caught in sary mogol (alay valley, southern kyrgyzstan) presented liver lesions with e. multilocularis from which the emsb target was amplified. the asian profile obtained was almost identical to one amplified from domestic dog faeces collected in a nearby village. th ... | 2015 | 26137938 |
| transmission ecosystems of echinococcus multilocularis in china and central asia. | from continental to regional scales, the zoonosis alveolar echinococcosis (ae) (caused by echinococcus multilocularis) forms discrete patches of endemicity within which transmission hotspots of much larger prevalence may occur. since the late 80s, a number of hotspots have been identified in continental asia, mostly in china, wherein the ecology of intermediate host communities has been described. this is the case in south gansu, at the eastern border of the tibetan plateau, in south ningxia, in ... | 2013 | 23734823 |
| unique sex chromosome systems in ellobius: how do male xx chromosomes recombine and undergo pachytene chromatin inactivation? | most mammalian species have heteromorphic sex chromosomes in males, except for a few enigmatic groups such as the mole voles ellobius, which do not have the y chromosome and sry gene. the ellobius (xx ♀♂) system of sex chromosomes has no analogues among other animals. the structure and meiotic behaviour of the two x chromosomes were investigated for males of the sibling species ellobius talpinus and ellobius tancrei. their sex chromosomes, despite their identical g-structure, demonstrate short s ... | 2016 | 27425629 |
| analysis of meiotic chromosome structure and behavior in robertsonian heterozygotes of ellobius tancrei (rodentia, cricetidae): a case of monobrachial homology. | synaptonemal complex (sc) chains were revealed in semisterile intraspecific f1 hybrids of ellobius tancrei blasius, 1884 (2n = 49, nf=56 and 2n=50, nf=56), heterozygous for robertsonian (rb) translocations. chains were formed by rb submetacentrics with monobrachial homology. chromosome synapsis in spermatocytes of these hybrids was disturbed, apparently because of the problematic release of the chromosomes from the sc chains. these hybrids suffer from low fertility, and our data support the opin ... | 2015 | 26752380 |
| a new form of the mole vole ellobius tancrei blasius, 1884 (mammalia, rodentia) with the lowest chromosome number. | the subterranean mole vole, ellobius tancrei, with aspecific variability in autosomes (2n = 31-54) and unusual sex chromosomes (xx in males and females), represents an amazing model for studying the role of chromosome changes in speciation. new materials from the upper reaches of the surkhob river in the pamiro-alay mountains resulted in the discovery of a new form with 2n = 30. the application of zoo-fish and g-banding methods allowed the detection of 13 pairs of autosomes as robertsonian metac ... | 2013 | 24260698 |
| a comparative analysis of the mole vole sibling species ellobius tancrei and e. talpinus (cricetidae, rodentia) through chromosome painting and examination of synaptonemal complex structures in hybrids. | a comparative genomic analysis was carried out in the mole vole sibling species ellobius tancrei and e. talpinus. performing fluorescent in situ hybridisation (zoo-fish) using chromosome paints from the field vole microtus agrestis showed no differences in the allocation of syntenic groups in the karyotypes of these sibling species. the only difference between their karyotypes was the position of the centromere in one pair of chromosomes, which is assumed to be the result of an inversion. to ver ... | 2012 | 22343488 |
| [the role of chromosome rearrangements in evolution of mole voles of genus ellobius (rodentia, mammalia)]. | modern mole voles of the genus ellobius are characterized by species-specific features of autosomes and sex chromosomes. owing to the use of the zoo-fish method, the nomenclature of chromosomes was refined and nonhomologous robertsonian translocations indistinguishable by g-staining were identified for ellobius tancrei, which is a species with a wide chromosome variation of the robertsonian type. the electron-microscopic analysis of synaptonemal complexes in f1 hybrids of forms with 2n = 50 and ... | 2010 | 21061637 |
| [dynamics of chromosome variation in mole voles ellobius tancrei (mammalia, rodentia) in pamiro-alai in the period from 1982 to 2008]. | analysis of a new karyological material of mole voles ellobius tancrei from a zone of high chromosome variation (pamiro-alai) in comparison with the data obtained 25 years ago showed a slight shift of the chromosome numbers on the western border of the robertsonian fan due to the expansion of the area of forms with a low chromosome number. in the central part of the fan zone, the process of active hybridization of forms with different chromosome numbers, but not of the original forms, is still g ... | 2010 | 20583600 |
| brain sexual differentiation and requirement of sry: why or why not? | brain sexual differentiation is orchestrated by precise coordination of sex steroid hormones. in some species, programming of select male brain regions is dependent upon aromatization of testosterone to estrogen. in mammals, these hormones surge during the organizational and activational periods that occur during perinatal development and adulthood, respectively. in various fish and reptiles, incubation temperature during a critical embryonic period results in male or female sexual differentiati ... | 2017 | 29200993 |
| meiotic nuclear architecture in distinct mole vole hybrids with robertsonian translocations: chromosome chains, stretched centromeres, and distorted recombination. | genome functioning in hybrids faces inconsistency. this mismatch is manifested clearly in meiosis during chromosome synapsis and recombination. species with chromosomal variability can be a model for exploring genomic battles with high visibility due to the use of advanced immunocytochemical methods. we studied synaptonemal complexes (sc) and prophase i processes in 44-chromosome intraspecific (ellobius tancrei × e. tancrei) and interspecific (ellobius talpinus × e. tancrei) hybrid mole voles he ... | 2020 | 33076404 |
| fathers and sons: physiological stress in male zaisan mole voles, ellobius tancrei. | the social environment can be stressful for at least some group members, resulting in elevated levels of glucocorticoid stress hormones (gc). patterns of the relationships between social rank and gc levels vary between species. in carnivores, primates and birds that live in permanent cooperative groups, helpers do not usually display physiological indicators of stress. very little is known about status-related gc differences within cooperative groups of rodents. in this laboratory study, we comp ... | 2019 | 30682343 |