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phenoloxidase production and vanillic acid metabolism by zygomycetes.the ability of 23 strains of zygomycetes to produce extracellular phenoloxidases was examined on solid media by using 10 different reagents. the results varied depending on the reagent and indicated that most of the strains were devoid of phenoloxidase activity. the production of inducible phenoloxidases was demonstrated by the bavendamm reaction. the study of the biotransformation of vanillic acid in synthetic medium indicated that the reaction most often obtained was the reduction of vanillic ...19921602986
[kinetics of the growth of colonies of mucor plumbeus and mortierella ramanniana fungi on agarized media with glucose].the growth kinetics of mucor plumbeus and mortierella ramanniana colonies was studied during cultivation of these two soil fungi on solid media with glucose as a limiting substrate. within the whole studied range of glucose concentrations (s), the radial growth rate of colonies (kr) can be satisfactorily described with the following equation that takes substrate inhibition into consideration: (formula: see text) the values of kinetic parameters for m. plumbeus and mort. ramanniana, respectively, ...19817219221
fungicin m4: a narrow spectrum peptide antibiotic from bacillus licheniformis m-4.the strain bacillus licheniformis m-4 produces a 3.4 kda hydrophilic peptide with antifungal activity, named fungicin m4. analysis of the purified peptide shows that it contains the amino acids glu (8), arg (5), pro (4), tyr (8), val (3), met (2) and orn (4). its inhibitory spectrum is restricted to microsporum canis cect 2797, mucor mucedo cect 2653, mucor plumbeus ccm 443, sporothrix schenckii cect 2799, bacillus megaterium and corynebacterium glutamicum cect 78. fungicin m4 exerts biocidal ac ...19947928782
purification, characterization, and lytic activity against naegleria fowleri of two amoebicins produced by bacillus licheniformis a12.bacillus licheniformis a12 produces two amoebolytic substances (amoebicins a12-a and a12-b) in liquid media during sporulation. both substances have been purified and characterized. they are heat- and protease-resistant peptides containing aspartic acid, glutamic acid, serine, proline, and tyrosine in a molar ratio of 5:2:2:2:2. no fatty acids or carbohydrates have been detected. their molecular weight is 1,430. purified amoebicins a12-a and a12-b exhibit amoebolytic action against naegleria fow ...19938517742
sensitivity of fungi to nikkomycin z.nikkomycin z inhibited colony radial extension (kr) and hyphal density in geotrichum candidum, trichoderma koningii, mucor plumbeus, and fusarium oxysporum, although the level of inhibition varied with the fungal species and was influenced by the concentration of nutrients in the culture medium. while g. candidum and m. plumbeus were sensitive to the inhibitory effects of nikkomycin z, t. koningii and f. oxysporum were relatively tolerant of concentrations of the antibiotic up to 100 mumol. nikk ...19968634944
chitinolytic activity at low temperature of an antarctic strain (a3) of verticillium lecanii.the chitinolytic activity of verticillium cfr. lecanii a3, a strain isolated from continental antarctica, was compared to those of two selected strains of trichoderma harzianum. after 72 h of incubation at 25 degrees c in media containing chitin as the sole carbon source, all strains showed the same enzyme activity (ca. 230 mu/ml); at 15 degrees c, the levels of enzyme activity of the three strains were similar to those obtained at 25 degrees c. at 5 degrees c, in contrast, the activity of v. le ...19989766230
microbial hydroxylation of natural drimenic lactones.incubation of confertifolin and isodrimenin with mucor plumbeus, aspergillus niger or rhizopus arrhizus gave in good yields the corresponding 3 beta-hydroxy derivatives. from isodrimenin, the known natural 7 alpha-hydroxy derivative (futronolide) was also obtained and its structure was definitely established by x-ray crystallographic study of its acetate derivative.199910513402
mycoflora in commercial pet foods.this article reports on the identification of mycoflora of 21 dry pet foods (12 belonging to dogs and 9 to cats) that corresponded to 8 commercial brands made in argentina and imported. the isolation frequency and relative density of the prevalent fungal genera are compared too. ten genera and fungi classified as mycelia sterilia were identified. the predominant genera were aspergillus (62%), rhizopus (48%), and mucor (38%). the most prevalent among aspergillus was aspergillus flavus followed by ...200111348013
growth of fungi and mycotoxin production on cheese under modified atmospheres.the use of modified atmospheres to prevent fungal growth and mycotoxin production in cheese was evaluated. eight fungal species: mucor plumbeus, fusarium oxysporum, byssochlamys fulva, b. nivea, penicillium commune, p. roqueforti, aspergillus flatus and eurotium chevalieri were inoculated onto cheese and incubated under conditions of decreasing concentrations of o2 (5% to < 0.5%) and increasing concentrations of co2 (20-40%). fungal growth was measured by colony diameter and ergosterol content. ...200111545212
microbial transformations of alpha-santonin.fungal biotransformations of alpha-santonin (1) were conducted with mucor plumbeus (atcc 4740), cunninghamella bainieri (atcc 9244), cunninghamella echinulata (atcc 9245), curvularia lunata (atcc 12017) and rhizopus stolonifer (atcc 10404). rhizopus stolonifer (atcc 10404) metabolized compound 1 to afford 3,4-epoxy-alpha-santonin (2) and 4,5-dihydro-alpha-santonin (3) while cunninghamella bainieri (atcc 9244), cunninghamella echinulata (atcc 9245) and mucor plumbeus (atcc 4740) were capable of m ...200415241928
antimicrobial activity of cinnamon and clove oils under modified atmosphere conditions.mixtures of cinnamon and clove oils were tested for inhibitory activity against important spoilage microorganism of intermediate moisture foods. four fungal species (aspergillus flavus, penicillium roqueforti, mucor plumbeus and eurotium sp.), four yeasts species (debaryomyces hansenii, pichia membranaefaciens, zygosaccharomyces rouxii and candida lipolytica), and two bacteria species (staphylococcus aureus and pediococcus halophilus) inoculated separately on agar plates were sealed in a barrier ...200616266767
novel microbial transformations of sclareolide.fungal catalysis of sclareolide (1) using mucor plumbeus (atcc 4740), cunninghamella blakesleeana (atcc 9245), cunninghamella echinulata (atcc 9244), curvularia lunata (atcc 12017) and aspergillus niger (atcc 1004), was performed. cunninghamella blakesleeana (atcc 9245) metabolized compound 1 to afford o(6)-sclareolide (2), 3beta,6alpha-dihydroxysclareolide (3), 9-hydroxysclareolide (4), along with three known metabolites, 1beta,3beta-dihydroxysclareolide (5), 3-oxosclareolide (6) and 3beta-hydr ...200717202714
in vitro susceptibility to fungicides by invertebrate-pathogenic and saprobic fungi.the effect of five fungicides, benomyl (1 mg/l), dodine (50 mg/l), manzate (100 mg/l), cupric sulphate (200 mg/l) and thiabendazole (4 mg/l) was tested under in vitro conditions on development of 15 isolates of fungi pathogenic for insects and other invertebrates (beauveria brongniartii, culicinomyces clavisporus, duddingtonia flagrans, hirsutella thompsonii, two metarhizium anisopliae, nomuraea rileyi, two isaria/paecilomyces spp., and sporothrix insectorum) and 13 isolates of contaminant fungi ...200717574540
steroid hydroxylation by whetzelinia sclerotiorum, phanerochaete chrysosporium and mucor plumbeus.the fungi whetzelinia sclerotiorum atcc 18687, phanerochaete chrysosporium atcc 24725 and mucor plumbeus atcc 4740 were examined for their ability to perform steroid biotransformations under single phase, pulse feed conditions. the steroids 3beta-hydroxyandrost-5-en-17-one (dehydroepiandrosterone) (1), 17beta-hydroxyandrost-4-en-3-one (testosterone) (5), 3beta-hydroxypregn-5-en-20-one (pregnenolone) (3), pregn-4-ene-3,20-dione (progesterone) (9), 17alpha,21-dihydroxypregn-4-ene-3,11,20-trione (c ...200717628623
diversity of microflora in the gut and casts of tropical composting earthworms reared on different substrates.the diversity of fungi, bacteria, yeast, actinomycetes and protozoa were analysed in the gut and casts of eudrilus eugeniae, lampito mauritii, eisenia fetida and perionyx excavatus, both qualitatively and quantitatively as influenced by different feed substrates like clay loam soil, cowdung and pressmud. while actinomycetes (streptomyces albus, s. somaliensis, nocardia asteroides, n. caviae and saccharomonosporia) were not digested by any of these species of worms, protozoa (amoeba proteus, a. t ...200717717992
evaluation of hot water treatments for management of ditylenchus dipsaci and fungi in daffodil bulbs.treatment of daffodil (narcissus pseudonarcissus) bulbs in a 0.37% formaldehyde water solution at 44 c for 240 minutes is a standard practice in california for management of the stem and bulb nematode, ditylenchus dipsaci. recent concern over the safety of formaldehyde and growers' requests for a shorter treatment time prompted a reevaluation of the procedure. the time (y, in minutes) required to raise the temperature at the bulb center from 25 to 44 c was related to bulb circumference (x, in cm ...199319279827
analysis of microbial communities in doenjang, a korean fermented soybean paste, using nested pcr-denaturing gradient gel electrophoresis.doenjang is a traditional korean fermented soybean paste that provides a major source of protein. the microbial diversity of 10 samples of doenjang (5 commercially manufactured products and 5 homemade products) was investigated using nested pcr-denaturing gradient gel electrophoresis (dgge). in the first step, the nearly complete 16s rrna and 18s rrna genes were amplified using universal primers. subsequently, these products were used as a template in a nested pcr to obtain fragments suitable fo ...200919324443
growth and mycotoxin production by food spoilage fungi under high carbon dioxide and low oxygen atmospheres.the influence of high carbon dioxide and low oxygen concentrations on growth by the foodborne fungal species, mucor plumbeus, fusarium oxysporum, byssochlamys fulva, byssochlamys nivea, penicillium commune, penicillium roqueforti, aspergillus flavus, eurotium chevalieri and xeromyces bisporus was investigated. production of aflatoxin by a. flavus, patulin by b. nivea and roquefortine c by p. roqueforti was also studied. fungal growth was evaluated under atmospheres consisting of 20, 40 and 60% c ...200919428138
selective activity of mucor plumbeus reductase towards (-)-camphorquinone.the biotransformation of 1r-(-)-camphorquinone, achieved by growing cells of four fungi species isolated from soil (mucor plumbeus, lecanicillium muscarium, thamnostylum sp. and syncephalastrum racemosum), was investigated in optimized culture media for each species. fungi were grown aerobically under shaking and their activities with respect to camphorquinone were monitored for 20 days by gas chromatography coupled to mass spectrometry (gcms). camphorquinone was found to be stable in control fl ...200919437056
screening pentachlorophenol degradation ability by environmental fungal strains belonging to the phyla ascomycota and zygomycota.pentachlorophenol (pcp) bioremediation by the fungal strains amongst the cork-colonising community has not yet been analysed. in this paper, the co- and direct metabolism of pcp by each of the 17 fungal species selected from this community were studied. using hierarchical data analysis, the isolates were ranked by their pcp bioremediation potential. fifteen isolates were able to degrade pcp under co-metabolic conditions, and surprisingly chrysonilia sitophila, trichoderma longibrachiatum, mucor ...200919543759
spores of mucor ramosissimus, mucor plumbeus and mucor circinelloides and their ability to activate human complement system in vitro.complement activation by spores of mucor ramosissimus, mucor plumbeus and mucor circinelloides was studied using absorbed human serum in the presence or absence of chelators (egta or edta). we found that the spore caused full complement activation when incubated with egta-mg2+ or without chelators, indicating that the alternative pathway is mainly responsible for this response. in order to compare activation profiles from each species, elisas for c3 and c4 fragments, mannan binding lectin (mbl), ...201020141371
growth and mycotoxin production by fungi in atmospheres containing 80% carbon dioxide and 20% oxygen.the effect of atmosphere containing 80% co(2) and 20% o(2) on growth of mucor plumbeus, fusarium oxysporum, byssochlamys fulva, byssochlamys nivea, penicillium commune, penicillium roqueforti, aspergillus flavus, eurotium chevalieri and xeromyces bisporus was investigated. production of aflatoxin by a. flavus, patulin by b. nivea, roquefortine c by p. roqueforti, and cyclopiazonic acid by p. commune was also studied. fungal growth was evaluated by three methods: colony diameter, hyphal length or ...201020864200
microbial transformation of marine halogenated sesquiterpenes.the sesquiterpene pacifenol is one of the main constituents of the red alga laurencia claviformis. earlier work on the semisynthetic derivatives of pacifenol afforded a series of halogenated sesquiterpenes. the aim of the present work was to obtain new hydroxylated derivatives of halogenated sesquiterpenes by means of microbial transformation using aspergillus niger, gibberella fujikuroi and mucor plumbeus. the best results were obtained with m. plumbeus. the microbiological transformation by m. ...201021299107
entrapment of mycelial fragments in calcium alginate: a general technique for the use of immobilized filamentous fungi in biocatalysis.transformation reactions on 3β,17β-dihydroxyandrost-5-ene using free fungal cells were compared with those carried out by macerated mycelia, immobilized in calcium alginate beads. six fungi were utilized in this study, namely rhizopus oryzae atcc 11145, mucor plumbeus atcc 4740, cunninghamella echinulata var. elegans atcc 8688a, aspergillus niger atcc 9142, phanerochaete chrysosporium atcc 24725 and whetzelinia sclerotiorum atcc 18687. the results show, for the first time, that encapsulated myce ...201222064215
a multi-criteria analysis approach for ranking and selection of microorganisms for the production of oils for biodiesel production.oleaginous microorganisms have potential to be used to produce oils as alternative feedstock for biodiesel production. microalgae (chlorella protothecoides and chlorella zofingiensis), yeasts (cryptococcus albidus and rhodotorula mucilaginosa), and fungi (aspergillus oryzae and mucor plumbeus) were investigated for their ability to produce oil from glucose, xylose and glycerol. multi-criteria analysis (mca) using analytic hierarchy process (ahp) and preference ranking organization method for the ...201525958151
studies on drug metabolism by fungi colonizing decomposing human cadavers. part ii: biotransformation of five model drugs by fungi isolated from post-mortem material.the present study investigated the in vitro metabolic capacity of 28 fungal strains isolated from post-mortem material towards five model drugs: amitriptyline, metoprolol, mirtazapine, promethazine, and zolpidem. each fungal strain was incubated at 25 °c for up to 120 h with each of the five models drugs. cunninghamella elegans was used as positive control. aliquots of the incubation mixture were centrifuged and 50 μl of the supernatants were diluted and directly analyzed by liquid chromatograph ...201524898183
effects of 7-hydroxycalamenene isolated from croton cajucara essential oil on growth, lipid content and ultrastructural aspects of rhizopus oryzae.the leaves and bark of croton cajucara, a shrub from the amazon region, have been used in folk medicine to treat diabetes, malaria, and gastrointestinal and liver disorders. the essential oil from the leaves, rich in linalool, presented antileishmanial and antimicrobial activities. a chemotype of this species was found with an essential oil rich in 7-hydroxycalamenene. during our studies of the c. cajucara essential oil, we isolated 7-hydroxycalamenene at > 98 % purity. the minimum inhibitory co ...201424841967
the effects of different carbon sources on the antifungal activity by lactic acid bacteria.lactobacillus rhamnosus r-2002 strain isolated from armenian pickled cheese sample has a fungicide effect, which was carried out by the first-time designed method. the fungicide effect of lab strain was expressed after 5 days of co-cultivation with mucor plumbeus and 6 days of co-cultivation with penicillium aurantioviolaceum. the growth as well as the antifungal activity of l. rhamnosus r-2002 was shown to directly depend on the nature of the medium's carbon source. the antifungal activity of t ...201727896483
molecular identification of mucor and lichtheimia species in pure cultures of zygomycetes.the mucorales are an important opportunistic fungi that can cause mucormycosis in immunocompromised patients. the fast and precise diagnosis of mucormycosis is very important because, if the diagnosis is not made early enough, dissemination often occurs. it is now well established that molecular methods such as polymerase chain reaction-restriction fragment length polymorphism (pcr-rflp) are feasible and reliable tools for the early and accurate diagnosis of mucormycosis agents.201627284399
identification of fungal ene-reductase activity by means of a functional screening.bioeconomy stresses the need of green processes promoting the development of new methods for biocatalyzed alkene reductions. a functional screening of 28 fungi belonging to ascomycota, basidiomycota, and zygomycota isolated from different habitats was performed to analyze their capability to reduce c=c double bonds towards three substrates (cyclohexenone, α-methylnitrostyrene, and α-methylcinnamaldehyde) with different electron-withdrawing groups, i.e., ketone, nitro, and aldehyde, respectively. ...201525986545
fourier transform infrared spectroscopy for the prediction of fatty acid profiles in mucor fungi grown in media with different carbon sources.fungal production of polyunsaturated fatty acids (pufas) is a highly potential approach in biotechnology. currently the main focus is directed towards screening of hundreds strains in order to select of few potential ones. thus, a reliable method for screening a high number of strains within a short period of time is needed. here, we present a novel method for screening of pufa-producing fungi by high-throughput microcultivation and ftir spectroscopy. in the study selected mucor fungi were grown ...201425208488
biodiversity of antifungal lactic acid bacteria isolated from raw milk samples from cow, ewe and goat over one-year period.antifungal lactic acid bacteria (alab) biodiversity was evaluated in raw milk from ewe, cow and goat over one year period. lactic acid bacteria were enumerated using 8 semi-selective media, and systematically screened for their antifungal activity against 4 spoilage fungi commonly encountered in dairy products. depending on the selective medium, between 0.05% (elliker agar) and 5.5% (lamvab agar) screened colonies showed an antifungal activity. the great majority of these active colonies origina ...201222364725
biomineralization of gold by mucor plumbeus: the progress in understanding the mechanism of nanoparticles' formation.this contribution describes the deposition of gold nanoparticles by microbial reduction of au(iii) ions using the mycelium of mucor plumbeus. biosorption as the major mechanism of au(iii) ions binding by the fungal cells and the reduction of them to the form of au(0) on/in the cell wall, followed by the transportation of the synthesized gold nanoparticles to the cytoplasm, is postulated. the probable mechanism behind the reduction of au(iii) ions is discussed, leading to the conclusion that this ...201728726315
biotransformation of an africanane sesquiterpene by the fungus mucor plumbeus.biotransformation of 8β-hydroxy-african-4(5)-en-3-one angelate by the fungus mucor plumbeus afforded as main products 6α,8β-dihydroxy-african-4(5)-en-3-one 8β-angelate and 1α,8β-dihydroxy-african-4(5)-en-3-one 8β-angelate, which had been obtained, together with the substrate, from transformed root cultures of bethencourtia hermosae. this fact shows that the enzyme system involved in these hydroxylations in both organisms, the fungus and the plant, acts with the same regio- and stereospecificity. ...201728034456
gastroprotective effects of new diterpenoid derivatives from azorella cuatrecasasii mathias & constance obtained using a β-cyclodextrin complex with microbial and chemical transformations.mulinane diterpenoids isolated from azorella species have displayed gastroprotective effects in animal models. in this study we have transformed the main constituent, mulin-11,13-dien-20 oic acid from this plant using the filamentous fungus mucor plumbeus and a β-cyclodextrin inclusion complex and we have obtained two main products with good yields (33% and 15% for compound 4 and 5, respectively) for further preparation of semisynthetic derivatives to evaluate their gastroprotective effects. in ...201627262597
the response of mucor plumbeus to pentachlorophenol: a toxicoproteomics study.pentachlorophenol (pcp) represents a critical concern worldwide due to its toxicity and recalcitrance to degradation. the capacity of mucor plumbeus to transform pcp into several detoxification metabolites, including tetrachlorohydroquinone and several phase ii conjugates, was observed by lc-hrms. the data obtained support the degradation pathway proposed previously. pcp effects in m. plumbeus, an unsequenced species, were investigated using a proteomics approach (bidimensional gel electrophores ...201323178873
degradation pathway of pentachlorophenol by mucor plumbeus involves phase ii conjugation and oxidation-reduction reactions.environmental pollution by pentachlorophenol (pcp) is a critical concern worldwide and fungal bioremediation constitutes an elegant and environment-friendly solution. mucorales from the zygomycota phylum are often observed to be competitive in field conditions and mucor plumbeus, in particular, can efficiently deplete pcp from media. the pathway for pcp degradation used by this fungus has not been investigated. in this study, pcp-derived metabolites were identified by liquid chromatography coupl ...201122074894
on the biotransformation of ent-trachylobane to ent-kaur-11-ene diterpenes.the microbiological transformation of trachinodiol (1) by the fungus mucor plumbeus afforded the corresponding 1α, 2α, 3α, and 17-hydroxy derivatives (2-4 and 6), respectively. 7β,16α,18-trihydroxy-ent-kaur-11-ene (sicanatriol) (5) was also obtained in this feeding. the biotransformation of 1 to give 5 by this fungus may occur by enzymatic abstraction of a hydrogen atom, allylic to the cyclopropane ring, and subsequent cleavage of this ring. this route is similar to that postulated by us in plan ...201121848313
microbial transformation of the diterpene mulin-11,13-dien-20-oic acid by mucor plumbeus.two new mulinane-type derivatives: 16-hydroxy mulin-11,13-dien-20-oic (2) acid and 7alpha,16-dihydroxy mulin-11,13-dien-20-oic (3) acid were obtained by microbial transformation of mulin-11,13-dien-20-oic acid (1), along with tyrosol (4) using liquid cultures of mucor plumbeus. the latter compound has not been previously identified in the genus mucor. structural elucidation of these metabolites was achieved using 1d- and 2d-nmr spectroscopy.200818470864
microbial transformation of the sesquiterpenoid (-)-maalioxide by mucor plumbeus.microbial transformation of the sesquiterpenoid (-)-maalioxide by the fungus mucor plumbeus gave three metabolites, 9beta-hydroxymaalioxide, 1beta-hydroxymaalioxide and 7beta-hydroxymaalioxide. 9beta-hydroxymaalioxide and its structure was established on the basis of its spectroscopic properties and chemical reactions.200616293273
stemodane and stemarane diterpenoid hydroxylation by mucor plumbeus and whetzelinia sclerotiorum.incubation of stemodin (1) with mucor plumbeus atcc 4740 resulted in the formation of 2alpha,6beta,13-trihydroxystemodane (2), 2alpha,3beta,13-trihydroxystemodane (3), 2alpha,11beta,13-trihydroxystemodane (4) and 2alpha,13,14-trihydroxystemodane (5), while stemodinone (7) afforded 6alpha,13-dihydroxystemodan-2-one (8) and 6alpha,12alpha,13-trihydroxystemodan-2-one (9). metabolites obtained from the bioconversion of stemarin (11) were 8,13,19-trihydroxystemarane (12) and 2alpha,13,19-trihydroxyst ...200516061265
the microbiological transformation of the diterpenes dehydroabietanol and teideadiol by mucor plumbeus.the microbiological transformation of dehydroabietanol (18-hydroxy-dehydroabietane) by mucor plumbeus led to 2alpha,18-dihydroxy-abieta-8,11,13,15-tetraene, 2alpha,15-dihydroxy-dehydroabietanol, 2alpha-hydroxy-15-methoxy-dehydroabietanol, 7beta-hydroxy-2-oxo-dehydroabietanol, 15-hydroxy-2-oxo-dehydroabietanol and 15,16-dihydroxy-2-oxo-dehydroabietanol, whilst that of teideadiol (1alpha,18-dihydroxy-dehydroabietane) gave 2alpha-hydroxy-teideadiol, 7alpha-hydroxy-teideadiol and 7beta-hydroxy-teide ...200312842138
biotransformation of the diterpenes epicandicandiol and candicandiol by mucor plumbeus.the microbiological transformation of the diterpene epicandicandiol (1) with mucor plumbeus gave foliol (3), sideritriol (5), and 7beta,16alpha,17,18-tetrahydroxy-ent-kaurane (7), while the incubation of candicandiol (2) gave 7alpha,9beta,18-trihydroxy-ent-kaur-16-ene (10), canditriol (11), and 7alpha,16alpha,17,18-tetrahydroxy-ent-kaurane (12). thus, the main difference observed in both feedings, resulting from the spatial change in the orientation of the 7-hydroxyl, from axial in the substrate ...200312662087
microbial transformation of cadina-4,10(15)-dien-3-one, aromadendr-1(10)-en-9-one and methyl ursolate by mucor plumbeus atcc 4740.the sesquiterpenes cadina-4,10(15)-dien-3-one (1) and aromadendr-1(10)-en-9-one (squamulosone) (14) along with the triterpenoid methyl ursolate (21) were incubated with the fungus mucor plumbeus atcc 4740. substrates 1, 14 and ursolic acid (20) were isolated from the plant hyptis verticillata in large quantities. m. plumbeus hydroxylated 1 at c-12 and c-14. when the iron content of the medium was reduced, however, hydroxylation at these positions was also accompanied by epoxidation of the exocyc ...200211853742
inactivation of mucor plumbeus by the combined actions of chitinase and high hydrostatic pressure.sporangiospores were treated with high hydrostatic pressure and/or fungal chitinase in order to study the inhibition of germination and growth of the food spoiling mold mucor plumbeus. total fungal inhibition was obtained either at 4.0 kbar or by 10 u/ml of chitinase from penicillium janthinellum. a pretreatment with 1 u/ml of the same chitinase reduced the pressure necessary to obtain complete spore inhibition to 3 kbar.199910573398
microbiological transformation of manoyl oxide derivatives by mucor plumbeus.biotransformations of jhanol (18-hydroxymanoyl oxide) (2), jhanidiol (1beta,18-dihydroxymanoyl oxide) (3), and 1-oxo-jhanol (1-oxo-18-hydroxymanoyl oxide) (4) by the fungus mucor plumbeus have been studied. in the incubation of 2 there exists a preference for hydroxylation at c-2(alpha) (8) and c-6(beta) (9-11) and, to a lesser degree, at c-1(alpha) (7), c-11(alpha) (6), and c-11(beta) (5 and 10). in the second substrate (3), the presence of a 1beta-hydroxyl group inhibits 6beta- or 11-hydroxyla ...19989784159
a new acetylcholinesterase inhibitor from green glycosylation of trachyloban-19-oic acid by mucor plumbeus.the in vitro metabolism of a widespread natural product, trachyloban-19-oic acid (1), by the fungal species mucor plumbeus was studied in a sucrose-yeast liquid medium. two products were isolated, and their structures were determined by spectroscopic means as 7β-hydroxytrachyloban-19-oic acid (5) and trachyloban-19-o-β-d-glucopyranosyl ester (6). to the best of our knowledge, compound 6 is herein reported by the first time in the literature. these compounds were assayed for acetylcholinesterase ...201729069140
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