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[diagnostic significance of the cuticular patterns on leaf surface of sarcandra glabra].the cuticular patterns on leaf surface of sarcandra glabra (thunb.) nakai were studied with scanning electron microscope. it was found that the cuticular patterns vary not only with the district of specimen collection, but also with the developmental stage of the leaf. the characteristics of the cuticular patterns are described in detail with 2 plates of illustrations.19902092582
[a new sesquiterpene lactone from sarcandra glabra]. 19883400479
[determination of fumaric acid in sarcandra glabra (thunb.) nakai by hplc].a method for the determination of fumaric acid in sarcandra glabra is reported. after the sample was pretreated with an anion exchange resin column, fumaric acid was determined on a spherisorb c18 column, with methanol-0.02 mol/l monobasic potassium (20:80, ph2.5) as the mobile phase and detected at 210 nm. the method is simple and accurate.199711038949
[determination of isofraxidin in sarcandra glabra (thunb.) nakai by hplc].to establish a method for the determination of isofraxidin in sarcandra glabra.199912205867
[studies on identification in sarcandra glabra by microscopic structure and tlc].studies on microcopic structure and tlc in sarcandra glabra (tunb.) nakai are reported. not only does it counteract weaknesses of former research, but it clarifies some matters well. the method to ideutify accurately this drug is provided.199912571902
[resource investigation and exploitable foreground of sarcandra glabra].the investigation showed the wild resource of sarcandra glabra (thumb.) nakai in the part region of south china including guangdong, guangxi and jiangxi was very plentiful and had a wonderful developmental foreground.200415658813
[the study on effect of sarcandra glabra on prevention and treatment of thrombocytopenia by chemotherapy].to investigate the effect of sarcandra glabra thunb on prevention and treatment of thrombocytopenia after chemotherapy with a large dosage.200515934240
transmitting tissue ecm distribution and composition, and pollen germinability in sarcandra glabra and chloranthus japonicus (chloranthaceae).and aims free-flowing surface exudates at the stigmatic (wet versus dry stigma) and adaxial epidermis at the site of angiospermy in carpels of chloranthaceous species have been proposed to comprise a continuous extracellular matrix (ecm) operating in pollen tube transmission to the ovary. the aim of this research was to establish the spatial distribution and histo/immunochemical composition of the ecm involved in pollen tube growth in sarcandra glabra and chloranthus japonicus (chloranthaceae).200516046459
two new triterpenoid saponins from sarcandra glabra.two new triterpenoid saponins, named sarcandroside a and b, have been isolated from sarcandra glabra (thunb) nakai. their structures have been established as 3beta,19alpha,20beta-trihydroxyurs-11,13 (18)-diene-28,20beta-lactone-3-o-beta-d-glucopyranosyl (1 --> 3)-[alpha-l-rhamnopyranosyl(1 --> 2)]-beta-d-xylopyranoside (1) and 3-o-beta-d-glucopyranosyl (1 --> 3)-[alpha-l-rhamnopyranosyl(1 --> 2)]-beta-d-xylopyranosyl-pomolic acid 28-o-beta-d-glucopyranosyl ester (2) by means of spectral and chem ...200516308199
hepatoprotective sesquiterpene glycosides from sarcandra glabra.six new sesquiterpene glycosides, compounds 1-6, with eudesmanolide, elemanolide, lindenane, and germacranolide sesquiterpene aglycons, along with one known compound, chloranoside a (7), have been isolated from the whole plant of sarcandra glabra. the structures of 1-6 were elucidated by chemical and spectroscopic methods including (1)h-(1)h cosy, hmqc, hmbc, and noesy nmr experiments. in addition, compounds 1-7 showed pronounced hepatoprotective activities against d-galactosamine-induced toxici ...200616643038
[determination of istanbulin a in sarcandra glabra].to determine istanbulin a in sarcandra glabra (thunb.) nakai.200616981453
ethyl acetate extract of chinese medicinal herb sarcandra glabra induces growth inhibition on human leukemic hl-60 cells, associated with cell cycle arrest and up-regulation of pro-apoptotic bax/bcl-2 ratio.sarcandra glabra (thunb.) nakai, colloquially known as caoshanhu, is a chinese medicinal herb with reported anti-tumor, anti-inflammatory, anti-viral and non-specific immunoenhancing properties. although the plant has been clinically used for treating a variety of diseases, its bioactive ingredients are largely unknown and its mode of action has never been investigated. in this study, the anti-tumor property of ethyl acetate (ea) extract of s. glabra was investigated by determining its in vitro ...200717203183
[high-performance liquid chromatography-electrospray ionization/tandem mass spectrometry of isofraxidin in sarcandra glabra].to establish a method for determining isofraxidin concentrations in sarcandra glabra and qingrexiaoyanning capsules with high-performance liquid chromatographic-mass spectrometry.200617259130
two new sesquiterpene lactones from sarcandra glabra.two new sesquiterpene lactones (1) and (2), along with three known sesquiterpenes, atractylenolide beta (3), chloranthalactone e (4), and ( - )-istanbulin a (5), were isolated from the whole plant of sarcandra glabra. the structures of two new compounds were established as 8beta,9alpha-dihydroxyeudesman-4(15),7(11)-dien-8alpha,12-olide (1) and 8beta,9alpha-dihydroxylindan-4(5),7 (11)-dien-8alpha,12-olide (2) on the basis of spectroscopic analysis. compound 3 was isolated from this genus for the ...200818470806
[studies on chemical constituents of sarcandra glabra].to study antibacterial chemical constituents of sarcandra glabra.200818619347
[studies on flavonoid glycosides of sarcandra glabra].to in vestigate the chemical constituents of sarcandra glabra and obtain a more comprehensive understanding on its effective components.200818841770
analysis of sarcandra glabra and its medicinal preparations by capillary electrophoresis.a simple, rapid, selective and reproducible capillary electrophoresis (ce) method was firstly developed for the identification and determination of isofraxidin and fumaric acid in a traditional chinese herb sarcandra glabra and its medicinal preparations. the buffer solution used in this method was 7.5 mm nah(2)po(4) and 7.5 mm borax solution adjusted to ph 8.60. the linear calibration range was 1.25-800 microg ml(-1) (r=0.9997) for isofraxidin and 10-800 microg ml(-1) (r=0.9992) for fumaric aci ...200318969120
[studies on chemical constituents and antibacterial activity from n-butanol extract of sarcandra glabra].to study the chemical constituents and the antibacterial activity from n-butanol extract of sarcandra glabra.200819007012
[studies on furmaric acid and isofraxidin content in sarcandra glabra of different provenances].to study the content variation of furmarid acid and isofraxidin in sarcandra glabra from 21 different provenances and provide the basis for resource utilization and quality optimization of s. glabra.200819007014
[comparison study of different extraction methods of sarcandra glabra].to compare the different extraction methods of sarcandra glabra (thunb.) nakai.200819180973
the anti-stress effects of sarcandra glabra extract on restraint-evoked immunocompromise.sarcandra glabra was a renowned herb traditionally used as herbal tea or food supplement to enhance mental efficiency and to recover from stress or fatigue in china. we investigated the effects of sarcandra glabra extract (sge), with chemical composition clearly showed by hplc fingerprint as quality control, on immunologic response including natural killer (nk) cell activity and its antioxidative capacity in splenocytes obtained from restraint mice. our results found that daily oral administrati ...200919182384
[study on the apoptosis of nasopharyngeal carcinoma cell line administrated with sarcandra glabra extracts in vivo and its mechanism].to evaluate the effect of sarcandra glabra extracts on anti-tumor and apoptosis of implanted human nasopharyngeal carcinoma cell lines in nude mice.200819230408
three novel sesquiterpene glycosides of sarcandra glabra.three new sesquiterpene glycosides, 8 beta,9 beta-epoxy-4 alpha-hydroxy-5 alpha h-lindan-7(11)-en-8 alpha,12-olide-15-o-beta-d-glucopyranoside (1, sarcaglaboside f), 4 alpha-hydroxy-5 alpha,8 beta h-lindan-7(11)-en-8 alpha,12-olide-15-o-beta-d-glucopyranoside (2, sarcaglaboside g), 4 alpha-hydroxy-5 alpha,8 beta h-eudesman-7(11)-en-8 alpha,12-olide-15-o-beta-d-glucopyranoside (3, sarcaglaboside h), together with five known compounds, chloranoside a (4), sarcaglaboside c (5), dihydrovomifoliol-o- ...200919336941
[effects of sarcandra glabra extract on immune activity in restraint stress mice].to study the protective effect of sarcandra glabra extract (sge) on immune system in restrained mice.200919382462
[study on the chemical constituents of sarcandra glabra by hplc-esi-ms/ms].to study and compare the main chemical constituents of sarcandra glabra and qingrexiaoyanning capsules which were extracted by acetic ether.200919645239
[photosynthetic characteristics of sarcandra glabra].to learn about the photosynthetic characteristics of sarcandra glabra and provide the theoretic references for its better planting.200919873771
sesquiterpenes and dimeric sesquiterpenoids from sarcandra glabra.two new sesquiterpenes, sarcandralactones a (1) and b (2), and five new dimeric sesquiterpenoids, sarcandrolides a-e (3-7), along with 10 known compounds were isolated from the whole plants of sarcandra glabra. their structures were elucidated on the basis of spectroscopic analysis. some of the new isolates exhibit significant cytotoxicities when tested against a small panel of tumor cell lines.201020038159
a new coumarin from sarcandra glabra.sarcandracoumarin (1), the first coumarin having a 1-phenylethyl substituent at the c-3 position, was isolated along with eleven known phenolic compounds from the water extract of sarcandra glabra. its structure was elucidated on the basis of spectroscopic data. compound 1 exhibited moderate or weak cytotoxicity against several tumor cell lines.201020060440
[sort similarity based on computational method for chemical fingerprinting].the key parts of chemical fingerprinting. however, the performance of the current whole similarity determining method sometimes is inadequate when the chromatograms of different classes are similar. the present study was focused on developing a sort similarity measure determining method for these problems. in this method, chemical fingerprint features are extracted from original chromatograms for classifying the samples. further, the fluctuations of chemical compositions among the same class sam ...201020450047
[chemical constituents from sarcandra glabra].to study the chemical constituents of the plant of sarcandra glabra and provide reference for the study of the bioactive substances.201020545194
two new sesquiterpenes from sarcandra glabra.phytochemical study of the ethanol extract of sarcandra glabra resulted in the isolation of two new sesquiterpenes, glabranols a (1) and b (2). their structures were elucidated as 8alpha,9alpha,15-trihydroxylinden-4,7(11)-dien-12,8beta-olide (1) and 1beta,4alpha,7beta,11-tetrahydroxyeudesmane (2), by spectroscopic methods including 1d- and 2d-nmr and fticr-ms.201021213965
[scavenging effect of sarcandra glabra powder on radiation-induced reactive oxygen species in the parotid gland of miniature pigs].to investigate the effect of sarcandra glabra in scavenging reactive oxygen species (ros) produced by ?-ray irradiation in the parotid gland of miniature pigs.201121269966
caffeic acid 3,4-dihydroxy-phenethyl ester (cadpe) induces cancer cell senescence by suppressing twist expression.comparing to traditional cytotoxic cancer therapy, therapy-induced cancer cell senescence treatment attracts much interest due to its similar effective, less side effect, and more efficiently cleared by immune cells. in this study, we demonstrate that unlike cape (caffeic acid phenethyl ester), cadpe (caffeic acid 3,4-dihydroxy-phenethyl ester), which is isolated from teucrium pilosum, inhibits human cancer cell growth and colony formation by inducing cancer cell senescence, not apoptosis. cadpe ...201121765040
chemical profiling of bioactive constituents in sarcandra glabra and its preparations using ultra-high-pressure liquid chromatography coupled with ltq orbitrap mass spectrometry.in this study, a fast and reliable method based on an ultra-high-pressure liquid chromatography coupled with photodiode-array detection (pda) and a linear ion trap high-resolution mass spectrometer (ltq-orbitrap xl) has been developed for the identification of bioactive constituents in the whole plant of sarcandra glabra and its related four preparations. by accurate mass measurements within 5ôçëppm error for each molecular ion and subsequent fragment ions in routine analysis, 50 compounds, incl ...201121818803
[sesquiterpenoids from the whole plant of sarcandra glabra].to study the sesquiterpenoid constituents in the whole plant of sarcandra glabra, silical column chromatography, sephadex lh-20, reverse phase ods column chromatography and preparative hplc were used to isolate 70% etoh extract of sarcandra glabra. the structures were elucidated based on spectroscopic data (hr-esi-ms, 1h nmr, 13c nmr, hsqc, hmbc and noesy). four sesquiterpenoids were obtained and identified as 4alpha-hydroxy-5alphah-lindan-8 (9)-en-8, 12-olide (1), chloranthalactone e (2), 8beta ...201122260027
characterization of phenolics of sarcandra glabra by non-targeted high-performance liquid chromatography fingerprinting and following targeted electrospray ionisation tandem mass spectrometry/time-of-flight mass spectrometry analyses.in this study, we successfully characterised the phenolic profiles of sarcandra glabra (thunb.) nakai by high-performance liquid chromatography (hplc) fingerprinting analyses and mass spectrometry (ms) identification. we first established a specific and valid hplc approach for fingerprint analysis of s. glabra based on hplc-uv detection. using several chemometric methods such as similarity evaluation and principal components analysis, we determined herb-markers peaks from many hplc peaks. the st ...201223497900
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