| identification of a precursor of beta-methyl-gamma-octalactone in the wood of sessile oak (quercus petraea (matt.) liebl.). | the 6'-o-gallate derivative of (3s, 4s)-4-beta-d-glucopyranosyloxy-3-methyloctanoic acid was isolated for the first time from the wood of sessile oak (quercus petraea (matt.) liebl.) and shown to be a precursor of cis-beta-methyl-gamma-octalactone. the structure of this precursor was determined by hrfab-ms, nmr, lcms, and chiral analysis of the liberated (3s,4s)-beta-methyl-gamma-octalactone on a chiral fused silica capillary column. optical rotation was shown to be identical to that of the same ... | 2000 | 10995355 |
| further characterization of galloyl pedunculagin as an effective autophosphorylation inhibitor of c-kinase in vitro. | the inhibitory effect of galloyl pedunculagin (gp) isolated from platycarya strobilacea on the activity and autophosphorylation of ca(2+)- and phospholipid-dependent protein kinase (c-kinase) was examined in vitro. it was found that (i). gp inhibited the activity (phosphorylation of complement c3 from guinea pig) of c-kinase alpha (rat brain) in a dose-dependent manner with an id(50) of approx. 0.12 micro m (ii). gp at lower doses (id(50)=approx. 6 nm) inhibited autophosphorylation of c-kinase a ... | 2002 | 12419947 |
| involvement of nf-kappab in the inhibitory actions of platycarya strobilacea on the tnf-alpha-induced monocyte adhesion to colon epithelial cells and chemokine expression. | oxidative stress and the activation of nuclear factor (nf)-kappab play crucial roles in the pathogenesis of inflammatory bowel disease (ibd). in the present study, we examined the effects of the ethanol extract of platycarya strobilacea sieb. stem (eps) on tnf-alpha-induced monocyte adhesion to ht29 human colon epithelial cells, an initial step of colon inflammation. eps contained high amount of polyphenols (0.241+/-0.017 mg of catechin equivalent/g of extract) and showed substantial dpph radica ... | 2008 | 18563354 |
| anti-wrinkle activity of platycarya strobilacea extract and its application as a cosmeceutical ingredient. | in order to investigate the potential of platycarya strobilacea fruit extract as an active ingredient for cosmetics, we measured their free-radical scavenging activity, elastase inhibitory activity, the expression of mmp-1 (matrix metalloproteinase-1), and type i collagen synthesis in normal human fibroblast cells. to isolate the main component compounds from p. strobilacea fruit extract, we purified the extract through solvent fractionation, column chromatography, and recrystallization. the com ... | 2010 | 20587350 |
| optimizing ultrasonic ellagic acid extraction conditions from infructescence of platycarya strobilacea using response surface methodology. | the infructescence of platycarya strobilacea is a rich source of ellagic acid (ea) which has shown antioxidant, anticancer and antimutagen properties. response surface methodology (rsm) was used to optimize the conditions for ultrasonic extraction of ea from infructescence of p. strobilacea. a central composite design (ccd) was used for experimental design and analysis of the results to obtain the optimal processing parameters. the content of ea in the extracts was determined by hplc with uv det ... | 2010 | 21060299 |
| ent-eudesmane sesquiterpenoids, galloyl esters of the oak lactone precursor, and a 3-o-methylellagic acid glycoside from the wood of platycarya strobilacea. | ent-eudesmane sesquiterpenoids, 8,11-dihydroxy-2,4-cycloeudesmane, 11-hydroxy-2,4-cycloeudesman-8-one and 2,4-cyclo-7(11)-eudesmen-8-one, were isolated from the wood of platycarya strobilacea, which has been used as an aromatic tree since at least the 18th century. on charring the wood, 2,4-cyclo-7(11)-eudesmen-8-one was detected in the smoke. in the charred wood, the concentrations of ellagitannins, such as galloyl pedunculagin, dramatically decreased, whereas concentrations of pentagalloyl glu ... | 2011 | 21440271 |