| ergot alkaloids produced by submerged cultures of claviceps zizaniae. | two ergopeptine alkaloids, alpha-ergocryptine (1) and its c(8) epimer alpha-ergocryptinine, have been isolated from the mycelium and fermentation broth of submerged cultures of claviceps zizaniae ccm 8240. the structure of 1 was determined by hplc/positive ion apci ms and nmr analysis. alkaloid concentrations of 10 microg/ml in 14-day-old fermentation broth and 1 mg/g of dry mycelium mass were found. these results are of considerable biotechnological interest since these were the only detectable ... | 2002 | 12141870 |