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preventive effect of sesquiterpenes from bay leaf on blood ethanol elevation in ethanol-loaded rat: structure requirement and suppression of gastric emptying.the methanolic extract from the leaves of laurus nobilis (bay leaf, laurel) potently inhibited the elevation of blood ethanol level in ethanol-loaded rat. through bioassay-guided separation, costunolide, dehydrocostus lactone, and santamarine were isolated as the active constituents and the alpha-methylene-gamma-butyrolactone structure was found to be essential for the preventive effect on ethanol absorption. in addition, the retardation of gastric emptying seemed to be partially involved in the ...199910509909
isolation and characterization of alkyl peroxy radical scavenging compound from leaves of laurus nobilis.etoh-soluble fraction from leaves of laurus nobilis (bay leaves) possessed the highest alkyl peroxy radical (roo*) scavenging activity among 120 kinds of herbs and edible plants, using the bioassay system which could determine the viability of staphylococcus aureus 209p by roo* cytotoxicity. after etoh-soluble fraction was partitioned with chloroform, ethylacetate, n-butanol and water, the ethylacetate-soluble fraction (l-ea) possessing the highest scavenging activity was further fractionated by ...200211824536
preliminary evaluation of cytotoxic properties of laurus nobilis leaf extracts.n-hexane, ethanol and water extracts of laurus nobilis l. leaves were evaluated for cytotoxic properties using the brine shrimp bioassay. only the n-hexane extract exhibited cytotoxic activity.200212048018
sesquiterpenes (costunolide and zaluzanin d) isolated from laurel (laurus nobilis l.) induce cell death and morphological change indicative of apoptotic chromatin condensation in leukemia hl-60 cells.sesquiterpenes (costunolide and zaluzanin d) were purified from laurel (laurus nobilis l.) and identified by mass, and 1h- and 13c-nmr. these sesquiterpenes displayed strong growth inhibitory effect against human promyelotic leukemia hl-60 cells. apoptotic morphological changes of the nucleus, including chromatin condensation were induced in the hl-60 cells treated with the sesquiterpenes. flow cytometric analysis showed that the hypodiploid nuclei of hl-60 cells were increased to 11.4, 47.0, an ...200312851709
chemical compositions and antibacterial effects of essential oils of turkish oregano (origanum minutiflorum), bay laurel (laurus nobilis), spanish lavender (lavandula stoechas l.), and fennel (foeniculum vulgare) on common foodborne pathogens.chemical compositions and inhibitory effects of essential oils of turkish oregano (origanum minutiflorum o. schwarz & p. h. davis), bay laurel (laurus nobilis l.), spanish lavender (lavandula stoechas subsp. stoechas l.), and fennel (foeniculum vulgare mill.) on escherichia coli o157:h7, listeria monocytogenes, salmonella typhimurium, and staphylococcus aureus were determined. after the essential oils were applied on the foodborne pathogens at doses of 0 (control), 5, 10, 20, 30, 40, 50, and 80 ...200415612826
specific induction of apoptosis by 1,8-cineole in two human leukemia cell lines, but not a in human stomach cancer cell line.we have investigated the effects of 1,8-cineole [the main component of essential oil prepared from bay-leaves laurus nobilis l.)] on dna of human leukemia cell lines, molt 4b, hl-60 and stomach cancer kato iii cells. specific induction of apoptosis by 1,8-cineole was observed in human leukemia molt 4b and hl-60 cells, but not in human stomach cancer kato iii cells. morphological changes showing apoptotic bodies were observed in the human leukemia hl-60 cells treated with 1,8-cineole. the fragmen ...200212066204
inhibitory mechanism of costunolide, a sesquiterpene lactone isolated from laurus nobilis, on blood-ethanol elevation in rats: involvement of inhibition of gastric emptying and increase in gastric juice secretion.basic inhibitory mechanisms of costunolide and its active component, alpha-methylene-gamma-butyrolactone (alpha-mgbl), on blood-ethanol elevation were investigated in rats. in normal rats, blood-ethanol elevation (30 min later) induced by 20% (v/v) ethanol [5 ml/kg, per os (p.o.)] was strongly inhibited by pretreatment (30 min earlier) with costunolide and alpha-mgbl (50 mg/kg, p.o.). in pylorus-ligated rats given ethanol, blood-ethanol level (30 min) was barely elevated compared with that of no ...200211912066
alcohol absorption inhibitors from bay leaf (laurus nobilis): structure-requirements of sesquiterpenes for the activity.through a bioassay-guided separation using inhibitory activity on blood ethanol elevation in oral ethanol-loaded rat, various sesquiterpenes having an alpha-methylene-gamma-butyrolactone moiety, costunolide (1), dehydrocostus lactone (2), zaluzanin d (3), reynosin (4), santamarine (5), 3alpha-acetoxyeudesma-1,4(15),11(13)-trien-12,6alpha-+ ++olide (6) and 3-oxoeudesma-1,4,11(13)-trien-12,6alpha-olide (7), were isolated as the active principle from the leaves of laurus nobilis (bay leaf, laurel). ...200011003152
inhibitory effects of sesquiterpenes from bay leaf on nitric oxide production in lipopolysaccharide-activated macrophages: structure requirement and role of heat shock protein induction.the methanolic extract from the leaves of laurus nobilis (bay leaf, laurel) was found to inhibit nitric oxide (no) production in lipopolysaccharide (lps)-activated mouse peritoneal macrophages. through bioassay-guided separation, fourteen known sesquiterpenes were isolated from the active fraction and were examined for ability to inhibit the no production. seven sesquiterpene lactones (costunolide, dehydrocostus lactone, eremanthine, zaluzanin c, magnolialide, santamarine and spirafolide) potent ...200010834299
polycyclic aromatic hydrocarbons in laurus nobilis leaves as a measure of air pollution in urban and rural sites of tuscany.the levels of 9 polycyclic aromatic hydrocarbons (pahs) 6 of which carcinogenic were measured in the leaves of evergreen tree (laurus nobilis) sampled in 13 locations in summer and winter in tuscany, italy. the carcinogenic pah levels were correlated with the pah air levels sampled at the same site. samples from larger towns had higher pah levels than those from medium and small towns. leaves collected in the center of larger cities had higher carcinogenic pah levels than samples from residentia ...19989519462
evaluation of the gastroprotective effect of laurus nobilis seeds on ethanol induced gastric ulcer in rats.the possible antiulcerogenic activity of laurus nobilis seeds was tested on experimentally (ethanol) induced gastric ulcer in rats. the results indicated antiulcerogenic activity for 20 and 40% aqueous extracts as well as for the oily fraction of these seeds. in acute toxicity studies, the aqueous extract was found safe with ld50 compared to oil ld50 0.33 ml/kg body weight.19979323999
allergic contact dermatitis to laurel (laurus nobilis l.): isolation and identification of haptens.two methods, using methylenelactone dimethylamino adducts, were used to remove selectively alpha-methylene gamma-butyrolactones from laurus nobilis l. extracts. isolated lactones were identified and "treated" extracts recovered. two guinea-pig groups were sensitized to crude extracts and "treated" extracts, respectively, and tested with primary sensitizer and with different lactones. only the first group showed strong skin reactions to crude extracts and to the lactones. treated extracts were sh ...19846476889
[study of the antimicrobial action of various essential oils extracted from malagasy plants. ii: lauraceae].the microbial growth inhibitory properties of some lauraceae essential oils, laurus nobilis, cinnamomum zeylanicum (cinnamon) and ravensara anisata were studied by the determination of their respective m.i.c. (minimal inhibitory concentration). five bacterial strains, one fungi and two yeasts were used to evaluate the essential oils inhibitory capacities. these vegetable extracts, with decrease activity, were range also: c. zeylanicum--bark greater than r. anisata--bark greater than c. zeylanicu ...19892633710
air pollution effects on the leaf structure of laurus nobilis, an injury resistant species. 19902322669
allergic contact dermatitis from dittrichia viscosa (l.) greuter.9 cases of contact sensitivity to dittrichia viscosa, mainly with an airborne pattern, are described. all patients reacted to the fresh leaf of the plant and to its ethereal extracts at 1 and 0.5% pet., and some of them also to that at 0.1% pet. positive reactions to frullania dilatata, laurus nobilis, some other members of the compositae, and helenin were observed, suggesting the diagnosis of a sesquiterpene-lactone-induced allergic contact dermatitis.19912044368
[the effect of food and drug herbal extracts on the hydrolysis and transport of sugars in the rat small intestine under different experimental conditions].viola tricolor, frigonella foenum-graecum, laurus nobilis were shown to reduce the glucose transport. the same was true for extract of tea leaves. fructose did not affect the velocity of free glucose absorption, slightly reduced the velocity of sucrose hydrolysis and absorption of produced hexoses and water. participation of active transport of carbohydrates in absorption processes occurring both in vitro and in vivo, is discussed.19921335906
two new sesquiterpene lactones from the leaves of laurus nobilis.as a part of our ongoing interest in new bioactive compounds from natural sources, we studied laurus nobilis (lauraceae). this plant is widespread in the mediterranean area and is used for medicinal and economic purposes. chromatographic separations on active extracts led to the isolation of two new sesquiterpene lactones, 5a,9-dimethyl-3-methylene-3,3a,4,5,5a,6,7,8-octahydro-1-oxacyclopenta[c]azulen-2-one (1) and 3beta-chlorodehydrocostuslactone (2). the structures of the new compounds were ide ...200616880666
anti-methicillin resistant staphylococcus aureus (mrsa) compounds isolated from laurus nobilis.we found that an extract from laurus nobilis l. (lauraceae) leaves showed antibacterial activity against methicillin-resistant staphylococcus aureus (mrsa). we purified two flavonoids as the effective compounds and identified them as kaempferol 3-o-alpha-l-(2'',4''-di-e-p-coumaroyl)-rhamnoside (c2) and kaempferol 3-o-alpha-l-(2''-z-p-coumaroyl-4''-e-p-coumaroyl)-rhamnoside (c3). both compounds showed strong antibacterial activity not only against mrsa but also against vancomycin-resistant entero ...200818758079
antimicrobial effects of turkish propolis, pollen, and laurel on spoilage and pathogenic food-related microorganisms.the antimicrobial activities of propolis extract, pollen extract, and essential oil of laurel (laurus nobilis l.) at concentrations from 0.02% to 2.5% (vol/vol) were investigated on bacteria (bacillus cereus, bacillus subtilis, escherichia coli, salmonella typhimurium, staphylococcus aureus, yersinia enterocolitica, enterococcus faecalis, and listeria monocytogenes), yeasts (saccharomyces cerevisiae and candida rugosa), and molds (aspergillus niger and rhizopus oryzae). pollen has no antimicrobi ...200818800911
the in vitro screening for acetylcholinesterase inhibition and antioxidant activity of medicinal plants from portugal.essential oil, ethanolic extract and decoction of 10 plant species from interior portugal were analyzed for their activity towards acetylcholinesterase (ache) enzyme and their antioxidant activity. of these, melissa officinalis, paronychia argentea, sanguisorba minor, hypericum undulatum and malva silvestris are used in herbal medicine, laurus nobilis and mentha suaveolens as condiments, and salvia officinalis, lavandula angustifolia and lavandula pedunculata also as aromatics. melissa officinal ...200616737790
biological activity evaluation of the oils from laurus nobilis of tunisia and algeria extracted by supercritical carbon dioxide.isolation of essential oil from dried and ground leaves of laurus nobilis l. from algeria and tunisia were obtained with two different methods: by means of classical hydrodistillation (hd) and by using carbon dioxide in the supercritical state (sfe). the effect of extraction pressure on the yield and composition of the l. nobilis volatile oil is examined. the best extraction conditions were as follows: pressure, 9.0 mpa; temperature, 323.15 k; 4 h of extraction and carbon dioxide flow, phi = 1.2 ...200919235023
synergistic effect of kaempferol glycosides purified from laurus nobilis and fluoroquinolones on methicillin-resistant staphylococcus aureus.in a previous study, we reported that two kaempferol glycosides isolated from laurus nobilis l., kaempferol-3-o-alpha-l-(2'',4''-di-e-p-coumaroyl)-rhamnoside (c2) and kaempferol-3-o-alpha-l-(2''-e-p-coumaroyl-4''-z-p-coumaroyl)-rhamnoside (c3), showed strong antibacterial activities against methicillin-resistant staphylococcus aureus (mrsa) and vancomycin-resistant enterococci. thereafter we found that these compounds greatly reduced the minimum inhibitory concentrations (mics) of some fluoroqui ...200919252301
microbial growth and quorum sensing antagonist activities of herbal plants extracts.antimicrobial and antiquorum sensing (aqs) activities of fourteen ethanolic extracts of different parts of eight plants were screened against four gram-positive, five gram-negative bacteria and four fungi. depending on the plant part extract used and the test microorganism, variable activities were recorded at 3 mg per disc. among the grampositive bacteria tested, for example, activities of laurus nobilis bark extract ranged between a 9.5 mm inhibition zone against bacillus subtilis up to a 25 m ...200919783935
evaluation of wound healing activity of allamanda cathartica. l. and laurus nobilis. l. extracts on rats.allamanda cathartica. l. is a perennial shrub used in traditional medicine for treating malaria and jaundice. laurus nobilis. l. is a tree and has been used for its astringent, healing and diuretic properties. the objective of this study was to investigate the aqueous extracts of allamanda and laurus nobilis to evaluate their wound healing activity in rats.200616597335
antimicrobial activities of the essential oils of various plants against tomato late blight disease agent phytophthora infestans.the aim of this study was to find an alternative to synthetic fungicides currently used in the control of devastating oomycete pathogen phytophthora infestans, causal agent of late blight disease of tomato. antifungal activities of essential oils obtained from aerial parts of aromatic plants such as oregano (origanum syriacum var. bevanii), thyme (thymbra spicata subsp. spicata), lavender (lavandula stoechas subsp. stoechas), rosemary (rosmarinus officinalis), fennel (foeniculum vulgare), and la ...200616463095
effect of different locations on the chemical composition of essential oils of laurel (laurus nobilis l.) leaves growing wild in turkey.the essential oil components of laurus nobilis gathered from seven different locations of turkey were identified by gas chromatography/mass spectrometry. the oil yields on a dry weight basis ranged between 1.4% to 2.6%. the major component was 1,8-cineole (51.73-68.48%); other predominant components were alpha-terpinyl acetate (4.04-9.87%), sabinene (4.44-7.75%), alpha-pinene (2.93-4.89%), beta-pinene (2.58-3.91%), terpinene-4-ol (1.33-3.24%), and alpha-terpineol (0.95-3.05%). minor qualitative ...200516176157
a simple method to obtain essential oils from salvia triloba l. and laurus nobilis l. by using microwave-assisted hydrodistillation.a microwave-assisted hydrodistillation protocol was modified to extract essential oils from leaves of salvia triloba l. and laurus nobilis l. the essential oils of these plants are generally obtained by hydrodistillation or steam distillation. the volatile compounds obtained by microwave-assisted hydrodistillation and hydrodistillation methods were analyzed by gc and gc/ms. both distillation methods and analytical results were compared. 1,8-cineole (46.8-54.2%) was the main component in the leaf ...200516047413
megastigmane and phenolic components from laurus nobilis l. leaves and their inhibitory effects on nitric oxide production.laurus nobilis l. leaves are widely used in cooking and in folk medicine. five new megastigmane glucosides (2-4, 7, and 9) named laurosides a-e and a new phenolic glucoside 12 were isolated from the methanolic extract of l. nobilis l. leaves, along with 10 known components: megastigmane (5), megastigmane glucosides (1, 6, 8, 10, and 11), aromatic compounds (13 and 14), and flavonoids (15 and 16). the structures and relative stereochemistry have been elucidated by one- and two-dimensional nuclear ...200415675799
repellency and toxicity of aromatic plant extracts against the mosquito culex pipiens molestus (diptera: culicidae).the insecticidal activities of essential oil extracts from leaves, flowers and roots of aromatic plants against fourth-instar larvae of the mosquito culex pipiens molestus forskal were determined. extracts of foeniculum vulgare mill were the most toxic, followed by those of ferula hermonis boiss, citrus sinensis osbeck, pinus pinea l, laurus nobilis l and eucalyptus spp with lc50 values of 24.5, 44.0, 60.0, 75.0, 117.0 and 120.0 mg litre(-1), respectively. combination tests between the lc50 and ...200515662650
tocopherol measurement in edible products of vegetable origin.since natural antioxidants present increasing interest for food industry due to their beneficial effect on health, new potential sources have been screened among edible aromatic plants and a microalgae, spirulina platensis. the determination was performed after optimising a previously validated method, because important differences have been found among values described in literature for tocopherol content in products of vegetable origin. values obtained ranged from 3.42 mg alpha-tocopherol/100 ...200415553148
the chemical composition of some lauraceae essential oils and their antifungal activities.the antifungal activity of aniba rosaeodora, laurus nobilis, sassafras albidum and cinnamomum zeylanicum essential oils were investigated against 17 micromycetes. among the tested fungal species were food poisoning, spoilage fungi, plant and animal pathogens. in order to determine fungistatic and fungicidal concentrations (mic and mfc) macrodilution and microdilution tests were used. linalool was the main component in the essential oil of a. rosaeodora, while 1.8-cineole was dominant in l. nobil ...200415478207
hot water soluble sesquiterpenes [anhydroperoxy-costunolide and 3-oxoeudesma-1,4(15),11(13)triene-12,6alpha-olide] isolated from laurel (laurus nobilis l.) induce cell death and morphological change indicative of apoptotic chromatin condensation in leukemia cells.hot water soluble (hws)-sesquiterpenes [anhydroperoxycostunolide and 3-oxo-eudesma-1,4(15),11(13)triene-12,6alpha-olide] were purified from laurel (laurus nobilis l.) and identified by mass, and 1h- and 13c-nmr. these hws-sesquiterpenes displayed strong growth inhibitory effect against human promyelotic leukemia hl-60 cells. apoptotic morphological changes of the nucleus, including chromatin condensation were induced in the hl-60 cells treated with the sesquiterpenes. flow cytometric analysis sh ...200414654907
analgesic and anti-inflammatory activity of the leaf essential oil of laurus nobilis linn.the leaf essential oil of laurus nobilis linn. (lauraceae) has been evaluated for antinociceptive and anti-inflammatory activities in mice and rats. the essential oil exhibited: (1) a significant analgesic effect in tail-flick and formalin tests; (2) a dose-dependent anti-inflammatory effect in the formalin-induced edema and (3) a moderate sedative effect at the anti-inflammatory doses. the analgesic and anti-inflammatory effect of the essential oil was comparable to reference analgesics and non ...200312916069
in vivo gastroprotective effects of five turkish folk remedies against ethanol-induced lesions.through evaluation of the data accumulated in data bank of turkish folk remedies (tuhib), five plant remedies, which are used to treat stomach ache were selected to test for their anti-ulcerogenic potency. in order to confirm the claimed activities, either decoction or methanol extracts were prepared from the roots of asphodelus aestivus and cichorium intybus, herbs of equisetum palustre and viscum album ssp. album and fruits of laurus nobilis, according to their folkloric application way and te ...200212426092
antimicrobial sesquiterpenoids from laurus nobilis l.activity-guided fractionations of leaf extracts from laurus nobilis l. led to the isolation of a known sesquiterpene lactone, deacetyl laurenobiolide (1). compound 1 showed antimicrobial activity against periopathic pathogens (actinomyces viscosus, porphyromonas gingivalis, prevotella intermedia and actinobacillus actinomycetemcomitans), opportunistic gram-positive bacteria (staphylococcus aureus and streptococcus pyogenes) and fungi (candida albicans, cryptococcus neoformans and aspergillus fum ...201121678158
trypanocidal terpenoids from laurus nobilis l.trypanocidal constituents of dried leaves of laurus nobilis l. (lauraceae) were examined. activity-guided fractionation of the methanol extract resulted in the isolation of two guaianolides, dehydrocostus lactone (1) and zaluzanin d (2), and a new p-menthane hydroperoxide, (1r,4s)-1-hydroperoxy-p-menth-2-en-8-ol acetate (3). the minimum lethal concentrations of these compounds against epimastigotes of trypanosoma cruzi were 6.3, 2.5, and 1.4 microm, respectively.200212419922
repellent activity of five essential oils against culex pipiens.essential oils extracted from the seeds of anise (pimpinella anisum), dried fruits of eucalyptus (eucalyptus camaldulensis), dried foliage of mint (mentha piperita) and basil (ocimum basilicum) and fresh foliage of laurel (laurus nobilis) were tested for their repellency against the adult females of culex pipiens. all essential oils showed repellency in varying degrees, eucalyptus, basil and anise being the most active.200616890387
evaluation of the wound healing effect of some jordanian traditional medicinal plants formulated in pluronic f127 using mice (mus musculus).the wound healing effect of the aqueous extracts of inula viscosa, ajuga chia, rubia taenifolia and parieteria diffusa, and the oil of laurus nobilis, dispersed in water, were examined. the 10% (w/w) pluronic f127 (pf127) was added to the applied preparations, in order to modify the aqueous extracts viscosity, and to stabilize the oil dispersion. a full thickness wound was made in the dorsal area of the mice. the wounds were treated with the different preparations with 12h intervals for four tim ...200716920296
bactericidal activity of black pepper, bay leaf, aniseed and coriander against oral isolates.present investigation focused on antibacterial potential of aqueous decoction of black pepper (piper nigrum l.), bay leaf (laurus nobilis l.), aniseed (pimpinella anisum l.), and coriander (coriandum sativum l.) against 176 bacterial isolates belonging to 12 different genera of bacterial population isolated from oral cavity of 200 individuals. the disc diffusion technique was employed. overall aqueous decoction of black pepper was the most bacterial-toxic exhibited 75% antibacterial activity as ...200616935829
comparative chemical composition and antioxidant activities of wild and cultivated laurus nobilis l. leaves and foeniculum vulgare subsp. piperitum (ucria) coutinho seeds.the chemical composition and antioxidant activities of wild and cultivated laurus nobilis leaves and foeniculum vulgare subsp. piperitum seeds were determined. differences were found in the total phenolic content of fennel. gc-ms analysis of the non polar fractions showed a different composition between wild and cultivated plants. cultivated laurel had a high content of terpenes such as linool, alpha-terpinol, alpha-terpinyl acetate, thymol, caryophyllene, aromandrene, selinene, farnesene, and c ...200617015951
contribution to the knowledge of the folk plant medicine in calabria region (southern italy).a series of research on plants used in calabria (southern italy) in the folk plant medicine was carried out in the last twenty years. the use of 104 taxa distributed into 42 families are described. among the major findings: ceterach officinarum as hypotensive; heliotropium europaeum in the case of urinary inflammations; silybum marianum for haemorrhoids; arundo donax for pertussis and cystitis; allium cepa for sties and flu; laurus nobilis as galactagogue; passiflora incarnata for burns, haemorr ...200717084993
characterization of the intracellular mechanisms involved in the antiaggregant properties of cinnamtannin b-1 from bay wood in human platelets.cinnamtannin b-1, a natural a-type proanthocyanidin recently identified as a radical scavenger component of laurus nobilis l., exerts antiaggregant and antiapoptotic effects in human platelets. here, we have investigated the intracellular mechanisms involved in the antiaggregant effects of cinnamtannin b-1. cinnamtannin b-1 showed a greater free radical scavenging activity than vitamin c, vitamin e, or trolox, among other antioxidants and reduced thrombin-evoked tubulin reorganization and platel ...200717602466
in vitro and in vivo control of alternaria alternata in cherry tomato by essential oil from laurus nobilis of chinese origin.many essential oils were reported to be used as natural, environmental friendly antimicrobial agents. the antifungal activity in vitro and in vivo of an essential oil extracted from chinese local laurus nobilis leaves against alternaria alternata has been studied.201425525652
dynamics of violaxanthin and lutein epoxide xanthophyll cycles in lauraceae tree species under field conditions.two xanthophyll cycles have been described in higher plants: the violaxanthin xanthophyll (v or vaz) cycle, which is present in all species, and the taxonomically restricted lutein epoxide xanthophyll (lx) cycle, which involves the light-induced de-epoxidation of lx to lutein (l) and its epoxidation back to lx in low light. laboratory experiments indicate that the first reaction occurs quickly, but the second reaction is much slower. we investigated the lx cycle under field conditions in several ...200717669731
screening of indigenous palestinian medicinal plants for potential anti-inflammatory and cytotoxic activity.organic extracts of 24 selected plant species, used by palestinian traditional healers to treat different illnesses and diseases, were tested for their anti-inflammatory and anti-tumoral activities. the plant selection was based on existing ethnobotanic information and interviews with local healers. the extracts of the plants under investigation were tested for their potential anti-tumor (cytotoxic) effect on the murine fibrosarcoma l929sa cells, and on the human breast cancer cells mda-mb231 an ...200717716845
evaluation of antitumor activity of peptide extracts from medicinal plants on the model of transplanted breast cancer in cbrb-rb(8.17)1iem mice.we studied antitumor effects of peptide extracts from plants on slowly growing mammary adenocarcinoma in cbrb-rb(8.17)1iem mice used as a model of breast cancer in humans. the antitumor effect of a single injection of the test peptides was evaluated by the delay of the appearance and growth of palpable breast cancer in mice over 4 weeks. peptides from hypericum perforatum and a mixture of chelidonium majus l., inula helenium l., equisetum arvense l., and inonotus obliquus exhibited maximum activ ...200819110595
bay laurel (laurus nobilis) as potential antiviral treatment in naturally bqcv infected honeybees.viral diseases are one of the multiple factors associated with honeybee colony losses. apart from their innate immune system, including the rnai machinery, honeybees can use secondary plant metabolites to reduce or fully cure pathogen infections. here, we tested the antiviral potential of laurus nobilis leaf ethanolic extracts on forager honeybees naturally infected with bqcv (black queen cell virus). total viral loads were reduced even at the lowest concentration tested (1mg/ml). higher extract ...201627235809
[antioxidant properties of essential oils].by the method of capillary gas-liquid chromatography we studied antioxidant properties and stability during the storage of hexane solutions of 14 individual essential oils from black and white pepper (piper nigrum l.), cardamom (elettaria cardamomum l.), nutmeg (myristica fragrans houtt.), mace (myristica fragrans houtt), juniperberry (juniperus communis l.), seed of fennel (foeniculum vulgare mill., var. dulce thelling), caraway (carvum carvi l.), dry leaves of cinnamon (cinnamomum zeylanicum b ...200920067158
suitability of two types of organic wastes for the growth of sclerophyllous shrubs on limestone debris: a mesocosm trial.this study investigated whether overlaying organic wastes directly on limestone debris allowed the growth of sclerophyllous shrubs; the aim was to explore the feasibility of rehabilitation of sites destroyed by quarrying activity. in an open air mesocosm experiment two types of organic material were compared: compost from municipal wastes (c) and a mixture of compost and poultry manure added with wheat husk (c-pw). mesocosms were pots (1m diameter, 60cm height) containing limestone debris covere ...201020092872
novel paraconiothyrium species on stone fruit trees and other woody hosts.coniothyrium-like fungi are common wood and soil inhabitants and hyperparasites on other fungi. they belong to different fungal genera within the pleosporales. several isolates were obtained on wood of different prunus species (plum, peach and nectarine) from south africa, on actinidia species from italy and on laurus nobilis from turkey. morphological and cultural characteristics as well as dna sequence data (5.8s nrdna, its1, its2, partial ssu nrdna) were used to characterise them. the isolate ...200820467483
volatile oil composition and antiproliferative activity of laurus nobilis, origanum syriacum, origanum vulgare, and salvia triloba against human breast adenocarcinoma cells.medicinal plants and culinary herbs have gained importance in the last decade as cytotoxic and antitumor agents. we hypothesized that some of the commonly used spices with reported antimicrobial activity might have antiproliferative activity. in the present study, selected spices used in jordan were chemically analyzed and investigated for their antiproliferative activity to the adenocarcinoma of breast cell line (mcf7). the composition of the essential oils of laurus nobilis l, origanum syriacu ...201020534330
in vitro and in vivo effects of laurus nobilis l. leaf extracts.the in vitro and in vivo antioxidant activities of different extracts of laurel leaves were studied. free radical scavenging capacity (rsc) was evaluated measuring the scavenging activity on the dpph, no, o(2)(.-) and oh radicals. the effects on lipid peroxidation (lp) were also evaluated. experimental results indicate that ethyl acetate extract of leaves has exhibited the largest rsc capacity in neutralization of dpph, no, o(2)(.-) and oh radicals. the same result was obtained in investigation ...201020657487
amelioration of oxygen and glucose deprivation-induced neuronal death by chloroform fraction of bay leaves (laurus nobilis).the purpose of this study was to determine whether the laurus nobilis chloroform fraction (lncf) protects against cerebral ischemia neuronal damage. human neuroblastoma sh-sy5y cells and brain slices from rats were subjected to oxygen and glucose deprivation (ogd), followed by reoxgenation with and without lncf. the viabilities of sh-sy5y cells and brain slices from the rats were 58.5±4.9% and 79.7±5.9% in the group subjected to ogd, and 80.4±0.4% and 97.2±1.9% at 4 µg/ml of lncf, respectively. ...201020944422
lauroside b, a megastigmane glycoside from laurus nobilis (bay laurel) leaves, induces apoptosis in human melanoma cell lines by inhibiting nf-κb activation.malignant melanoma is a highly aggressive tumor that frequently resists chemotherapy, so the search for new agents for its treatment is of great importance. in the present study, the antiproliferative propensity against human melanoma cell lines of lauroside b (1), a megastigmane glycoside isolated from laurus nobilis (bay laurel) leaves, was investigated. this compound suppressed the proliferation of three human melanoma cell lines, namely, a375, wm115, and sk-mel-28. the 1-induced inhibition o ...201021188975
spirafolide from bay leaf (laurus nobilis) prevents dopamine-induced apoptosis by decreasing reactive oxygen species production in human neuroblastoma sh-sy5y cells.reactive oxygen species (ros) are important mediators in many neurodegenerative diseases including alzheimer's disease and parkinson's disease. this study tested the neuroprotective effects of spirafolide, a compound purified from the leaves of laurus nobilis l. (lauraceae), against dopamine (da)-induced apoptosis in human neuroblastoma sh-sy5y cells. following a 24-h exposure of cells to da (final conc., 0.6 mm), we observed a marked increase in apoptosis, increased generation of ros and decrea ...201021191760
rhizosphere dynamics during phytoremediation of olive mill wastewater.the potential of phytoremediation as a treatment option for olive mill wastewater (omw) was tested on five perennial tree species. cupressus sempervirens and quercus ilex proved tolerant to six-month omw treatment followed by six-month water irrigation, whereas salix sp. and laurus nobilis and, later, pinus mugo suffered from phytotoxic effects. test plants were compared to controls after treatment and irrigation, by monitoring biochemical and microbiological variations in the rhizosphere soil. ...201021256739
gastroprotective effect and antioxidant properties of different laurus nobilis l. leaf extracts.laurus nobilis l. (family lauraceae) is an evergreen tree widely distributed in the mediterranean area and europe. it is used in folk medicine of different countries as a stomachic and carminative as well as in treatment of gastric diseases. extracts obtained with different methods (methanol and chloroform) from laurel leaves were evaluated for their gastroprotective activities in the rat. the antioxidant capacity of the different extracts has been also measured in vitro. in order to confirm the ...201121314364
inhibitory effects of costunolide isolated from laurus nobilis on ige-induced degranulation of mast cell-like rbl-2h3 cells and the growth of y16 pro-b cells.this study investigated the inhibitory effects of costunolide isolated from the leaves of laurus nobilis l. (lauraceae) on basophil-mediated allergic reactions and interleukin (il)-5-mediated b cell growth. the effects of costunolide on ╬▓-hexosaminidase (a key parameter of degranulation) release and il-4 expression in rat basophilic leukemia (rbl-2h3) cells were determined by measuring ╬▓-hexosaminidase activity and by semi-quantitative rt-pcr, respectively. the effects of costunolide on y16 pr ...201121674633
Neuroprotective Effects of 3+¦-Acetoxyeudesma-1,4(15),11(13)-trien-12,6+¦-olide Against Dopamine-Induced Apoptosis in the Human Neuroblastoma SH-SY5Y Cell Line.Dopamine (DA), as a neurotoxin, can elicit severe Parkinson's disease-like syndrome by elevating intracellular reactive oxygen species (ROS) levels and apoptotic activity. We examined the inhibitory effects of 3+¦-acetoxyeudesma-1,4(15),11(13)-trien-12,6+¦-olide (AETO), purified from the leaves of Laurus nobilis L., on DA-induced apoptosis and +¦-synuclein (+¦-syn) formation in dopaminergic SH-SY5Y cells. AETO decreased the active form of caspase-3 and the levels of p53, which were accompanied b ...201121688047
Antioxidant and antiproliferative activity of Laurus nobilis L. (Lauraceae) leaves and seeds essential oils against K562 human chronic myelogenous leukaemia cells.The antioxidant and antiproliferative activities of the essential oils from Laurus nobilis leaves and seeds in relation to their composition were analysed. The most abundant components of the leaf essential oil were 1,8-cineole, 1-p-menthen-8-ethyl acetate, linalool and sabinene, while the seed oil was characterised by ß-ocimene, 1,8-cineole, a-pinene and ß-pinene as main constituents. Both seed and leaf essential oils exhibited a scavenging effect on the DPPH radical, with IC(50) values of 66.1 ...201122017546
antidiarrheal activity of laurus nobilis l. leaf extract in rats.abstract in jordan, the leaves of laurus nobilis (family lauraceae) have been used in folk medicine for the treatment of diarrhea, among other ailments. however, the ethnopharmacology of this plant needs to be scientifically validated. the present work was carried out to evaluate the scientific basis of the antidiarrheal effect of the aqueous extract of l. nobilis leaf. l. nobilis leaf extract significantly inhibited castor oil-induced diarrhea (effective concentration producing 50% of the max ...201122082096
natural product htp screening for attenuation of cytokine-induced neutrophil chemo attractants (cincs) and no2- in lps/ifnγ activated glioma cells.chronic and acute central nervous system (cns) inflammation are contributors toward neurological injury associated with head trauma, stroke, infection, parkinsons or alzheimers disease. cns inflammatory illnesses can also contribute toward risk of developing glioblastoma multiforme (gbm). with growing public interest in complementary and alternative medicines (cams), we conduct a high throughput (htp) screening of >1400 natural herbs, plants and over the counter (otc) products for anti-inflammat ...201727956075
effects of laurus nobilis (lauraceae) on biomphalaria glabrata (say, 1818).experiments were carried out using aqueous extracts from leaves and flowers of laurus nobilis on biomphalaria glabrata. treatments were performed on blastula stage (+/- 15 h after first cleavage) and on adult snails (11-18 mm). in both instances they were exposed for 24 h to different concentrations of the extracts on snails (200 to 2500 ppm) and embryos (20 to 300 ppm) at 25 +/- 1 degree c. the embryos were observed for a period of 20 days after treatment and the snails for 10 days. results obt ...20123509189
two-dimensional pca highlights the differentiated antitumor and antimicrobial activity of methanolic and aqueous extracts of laurus nobilis l. from different origins.natural matrices are important sources of new antitumor and antimicrobial compounds. species such as laurus nobilis l. (laurel) might be used for this purpose, considering its medicinal properties. herein, in vitro activity against human tumor cell lines, bacteria, and fungi was evaluated in enriched phenolic extracts. specifically, methanol and aqueous extracts of wild and cultivated samples of l. nobilis were compared considering different phenolic groups. principal component analysis (pca) wa ...201424826380
an evidence-based review on medicinal plants used as insecticide and insect repellent in traditional iranian medicine.insects can be the cause of major ecological problems; they can transmit microbes and parasites that affect humans, and damage food crops, trees, and homes. the total economic cost of insect-related damage and disease is immeasurable. in traditional iranian medicine (tim), several medicinal plants have been identified as insecticides or insect repellents, but many of them are still unknown. therefore, the aim of this study was to review the insecticidal or insect repellent activity of certain me ...201627186389
laurus nobilis, zingiber officinale and anethum graveolens essential oils: composition, antioxidant and antibacterial activities against bacteria isolated from fish and shellfish.several bacterial strains were isolated from wild and reared fish and shellfish. the identification of these strains showed the dominance of the aeromonas hydrophila species in all seafood samples, followed by staphylococcus spp., vibrio alginolyticus, enterobacter cloacae, klebsiella ornithinolytica, klebsiella oxytoca and serratia odorifera. the isolates were studied for their ability to produce exoenzymes and biofilms. the chemical composition of the essential oils from laurus nobilis leaves, ...201627782086
cytotoxic activity of essential oils from labiatae and lauraceae families against in vitro human tumor models.the aim of this work was to study the cytotoxicity of essential oils and their identified constituents from sideritis perfoliata, satureia thymbra, salvia officinalis, laurus nobilis and pistacia palestina.200717970073
phytochemical analysis and in vitro antiviral activities of the essential oils of seven lebanon species.the chemical composition of the essential oils of laurus nobilis, juniperus oxycedrus ssp. oxycedrus, thuja orientalis, cupressus sempervirens ssp. pyramidalis, pistacia palaestina, salvia officinalis, and satureja thymbra was determined by gc/ms analysis. essential oils have been evaluated for their inhibitory activity against sars-cov and hsv-1 replication in vitro by visually scoring of the virus-induced cytopathogenic effect post-infection. l. nobilis oil exerted an interesting activity agai ...200818357554
comparison of chemical composition of the essential oil of laurus nobilis l. leaves and fruits from different regions of hatay, turkey.the essential oils of the leaves and fruits from bay (laurus nobilis l.) grown in antakya, yayladagi and samandagi were isolated by solvent extraction and analysed by capillary gas chromatography (gc), gas chromatography and mass spectrometry (gc/ms). in antakya, yayladagi and samandagi the chemical compositions of the fruits and leaves were similar according to qualitative and quantitative analysis. although in both fruits and leaves the major component was found to be 1.8-cineole a concentrati ...200718405104
nematicidal activity of essential oils and volatiles derived from portuguese aromatic flora against the pinewood nematode, bursaphelenchus xylophilus.twenty seven essential oils, isolated from plants representing 11 families of portuguese flora, were screened for their nematicidal activity against the pinewood nematode (pwn), bursaphelenchus xylophilus. the essential oils were isolated by hydrodistillation and the volatiles by distillation-extraction, and both were analysed by gc and gc-ms. high nematicidal activity was achieved with essential oils from chamaespartium tridentatum, origanum vulgare, satureja montana, thymbra capitata, and thym ...201022736831
antibacterial and antibiofilm activities of polysaccharides, essential oil, and fatty oil extracted from laurus nobilis growing in lebanon.to evaluate the antibacterial activity of the extracts of laurus nobilis against three gram-positive bacteria (staphylococcus aureus atcc 25923, enterococcus faecalis atcc 29212 and staphylococcus epidermidis cip 444) and two gram-negative bacteria (escherichia coli atcc 35218 and pseudomonas aeruginosa atcc 27853). also, the antibiofilm activity has been investigated against the biofilm produced by staphylococcus epidermidis cip 444.201425312182
natural product htp screening for antibacterial (e.coli 0157:h7) and anti-inflammatory agents in (lps from e. coli o111:b4) activated macrophages and microglial cells; focus on sepsis.acute systemic inflammatory response syndrome arising from infection can lead to multiple organ failure and death, with greater susceptibility occurring in immunocompromised individuals. moreover, sub-acute chronic inflammation is a contributor to the pathology of diverse degenerative diseases (parkinson's disease, alzheimer's disease and arthritis). given the known limitations in western medicine to treat a broad range of inflammatory related illness as well as the emergence of antibiotic resis ...201627846826
isolation and functional characterization of carotenoid cleavage dioxygenase-1 from laurus nobilis l. (bay laurel) fruits.bay laurel (laurus nobilis l.) is an agriculturally important tree used in food, drugs, and the cosmetics industry. many of the health beneficial properties of bay laurel are due to volatile terpene metabolites that they contain, including various norisoprenoids. despite their importance, little is known about the norisoprenoid biosynthesis in laurus nobilis fruits. we found that the volatile norisoprenoids 6-methyl-5-hepten-2-one, pseudoionone, and β-ionone accumulated in laurus nobilis fruits ...201526359684
in vitro antibacterial activity of several plant extracts and oils against some gram-negative bacteria.medicinal plants are considered new resources for producing agents that could act as alternatives to antibiotics in the treatment of antibiotic-resistant bacteria. the aim of this study was to evaluate the antibacterial activity of 28 plant extracts and oils against four gram-negative bacterial species.201424453392
acylated kaempferol glycosides from laurus nobilis leaves and their inhibitory effects on na+/k+-adenosine triphosphatase.na(+)/k(+)-adenosine triphosphatase (atpase) inhibitors have considerable therapeutic potential against some heart diseases like congestive heart failure and cardiac arrhythmias. through bioassay-guided separation of the leaf extract of laurus nobilis, six acylated kaempferol glycosides (compounds 1-6) were isolated. their structures were determined on the basis of spectroscopic analysis and comparison with reported data. all the isolates were subjected to in vitro bioassays to evaluate their in ...201222382332
preliminary examination of herbal extracts on the inhibition of helicobacter pylori.this work aims at describing the traditional uses, to determine the antimicrobial potential of two different extracts hexane, acetone of the leaves of citrus unshiu, citrus sinensis, citrus limon, laurus nobilis, citrus paradisi on clinical strain of h. pylori in a bid to identify potential sources of cheap starting materials for the synthesis of new drugs. h. pylori strain was a culture collection of hacettepe university, turkey.201424653559
laurel leaf extracts for honeybee pest and disease management: antimicrobial, microsporicidal, and acaricidal activity.a diverse set of parasites and pathogens affects productivity and survival of apis mellifera honeybees. in beekeeping, traditional control by antibiotics and molecules of synthesis has caused problems with contamination and resistant pathogens. in this research, different laurus nobilis extracts are tested against the main honeybee pests through an integrated point of view. in vivo effects on bee survival are also evaluated. the ethanol extract showed minimal inhibitory concentration (mic) value ...201424288051
laurus nobilis leaf extract mediated green synthesis of zno nanoparticles: characterization and biomedical applications.the present study reports the green synthesis of zinc oxide nanoparticles using the aqueous leaf extract of laurus nobilis (ln-zno nps) by co-precipitation method. the synthesized ln-zno nps were characterized by uv-vis spectroscopy, ftir, xrd, tem, sem and edx. ln-zno nps were crystalline in nature, flower like and have hexagonal wurtzite structure with a mean particle size of 47.27nm. the antibacterial activity of ln-zno nps was greater against gram positive (staphylococcus aureus) bacteria th ...201627788479
antibacterial, anti-swarming and anti-biofilm formation activities of chamaemelum nobile against pseudomonas aeruginosa.chamomile (chamaemelum nobile) is widely used throughout the world, and has anti-inflammatory, deodorant, bacteriostatic, antimicrobial, carminative, sedative, antiseptic, anti-catarrhal, and spasmolytic properties. because of the increasing incidence of drug-resistant bacteria, the development of natural antibacterial sources such as medical herbs for the treatment of infectious diseases is necessary. extracts from different plant parts such as the leaves, flowers, fruit, and bark of combretum ...201526312934
comparative investigation of umbellularia californica and laurus nobilis leaf essential oils and identification of constituents active against aedes aegypti.umbellularia californica (california bay laurel) and laurus nobilis (mediterranean bay laurel) leaves may be mistaken or used as a substitute on the market due to their morphological similarity. in this study, a comparison of anatomical and chemical features and biological activity of both plants is presented. l. nobilis essential oil biting deterrent and larvicidal activity were negligible. on the other hand, u. californica leaf oil showed biting deterrent activity against aedes aegypti . the i ...201324266426
screening of 20 commonly used iranian traditional medicinal plants against urease.infection with helicobacter pyloriis the most common cause of stomach and duodenal ulcers. about more than 80 % of people are infected with h. pylori in developing countries. h. pylori uses urease enzyme product "ammonia" in order to neutralize and protect itself from the stomach acidic condition and urease enzyme activity has been shown to be essential to the colonization of h. pylori. inhibitory activity of 20 traditional medicinal plants were examined and evaluated against jack bean urease ac ...201424711846
systemic allergic dermatitis caused by sesquiterpene lactones.patients with compositae sensitization are routinely warned against the ingestion of vegetables, spices, teas and herbal remedies from this family of plants. the evidence for the occurrence of systemic allergic dermatitis caused by sesquiterpene lactone-containing plants is mostly anecdotal and based on statements from patients rather than scientific data. however, a few clinical reports on accidental sensitization and exposure and oral challenge prove the existence of this kind of reaction, mos ...201727568784
anticancer activity of certain herbs and spices on the cervical epithelial carcinoma (hela) cell line.acetone extracts of selected plant species were evaluated for their in vitro cytotoxicity against a noncancerous african green monkey kidney (vero) cell line and an adenocarcinoma cervical cancer (hela) cell line. the plants studied were origanum vulgare l. (oregano), rosmarinus officinalis l. (upright and ground cove rosemary), lavandula spica l. (lavender), laurus nobilis l. (bay leaf), thymus vulgaris l. (thyme), lavandula x intermedia l. (margaret roberts lavender), petroselinum crispum mill ...201222649474
biophysical characteristics of successful oilseed embryo cryoprotection and cryopreservation using vacuum infiltration vitrification: an innovation in plant cell preservation.heterogeneity in morphology, physiology and cellular chemistry of plant tissues can compromise successful cryoprotection and cryopreservation. cryoprotection is a function of exposure time × temperature × permeability for the chosen protectant and diffusion pathway length, as determined by specimen geometry, to provide sufficient dehydration whilst avoiding excessive chemical toxicity. we have developed an innovative method of vacuum infiltration vitrification (viv) at 381 mm (15 in) hg (50 kpa) ...201424788797
coping with drought-induced xylem cavitation: coordination of embolism repair and ionic effects in three mediterranean evergreens.embolism repair and ionic effects on xylem hydraulic conductance have been documented in different tree species. however, the diurnal and seasonal patterns of both phenomena and their actual role in plants' responses to drought-induced xylem cavitation have not been thoroughly investigated. this study provides experimental evidence of the ability of three mediterranean species to maintain hydraulic function under drought stress by coordinating the refilling of xylem conduits and ion-mediated enh ...201424488800
chemical composition and fumigant toxicity of some essential oils against ephestia kuehniella.the chemical constituents of some essential oils extracted from aromatic plants (savory, satureja thymbra l.; turkish oregano, origanum onites l.; myrtle, myrtus communis l.; marjoram, origanum majorana l.; laurel, laurus nobilis l.; lemon, citrus limon l.; sticky goosefoot, chenopodium botrys l.; and tansy, tanecetum armenum [dc.] suchultz bip.) were analyzed by gas chromatography-mass spectrometry. fumigant toxicity of volatile compounds was tested against mediterranean flour moth, ephestia ku ...201121882685
nutraceutical properties of dietary plants extracts: prevention of diabetic nephropathy through inhibition of glycation and toxicity to erythrocytes and hek293 cells.glycated albumin is reported to elicit pathobiologic effects in diabetic nephropathy and abrogating its biologic effects has novel therapeutic potential.201525243884
in vitro study of the antifungal activity of essential oils obtained from mentha spicata, thymus vulgaris and laurus nobilis.the aim of this study was to determine the antifungal activity of the essential oils isolated from three aromatic plants against 13 filamentous fungal strains. the major constituents of mentha spicata, thymus vulgaris, and laurus nobilis essential oils were carvone (52.2%), linalool (78.1%), and 1,8-cineole (45.6%), respectively. m. spicata essential oil exhibited the strongest activity against all tested fungi in which fusarium graminearum, f.moniliforme, and penicillium expansum were the most ...201627697030
isolation and characterization of putative endophytic bacteria antagonistic to phoma tracheiphila and verticillium albo-atrum.a collection of 200 bacterial isolates recovered from citrus plants (citrus limon, citrus sinensis, and citrus reticulata), medicago truncatula and laurus nobilis, was established. in vitro screening indicated that 28 isolates exhibited an inhibitory activity against the vascular pathogens phoma tracheiphila and verticillium albo-atrum. isolates were screened according to their hydrolytic activities, plant growth-promoting bacteria (pgpb) abilities, as well as for the presence of nonribosomal pe ...201425074353
empirical prediction and validation of antibacterial inhibitory effects of various plant essential oils on common pathogenic bacteria.in this study, fractional compound composition, antioxidant capacity, and phenolic substance content of 14 plant essential oils-anise (pimpinella anisum), bay leaves (laurus nobilis), cinnamon bark (cinnamomum verum), clove (eugenia caryophyllata), fennel (foeniculum vulgare), hop (humulus lupulus), istanbul oregano (origanum vulgare subsp. hirtum), izmir oregano (origanum onites), mint (mentha piperita), myrtus (myrtus communis), orange peel (citrus sinensis), sage (salvia officinalis), thyme ( ...201525764982
trends in wild food plants uses in gorbeialdea (basque country).despite wild food plants' potential nutritional and economic value, their knowledge and consumption is quickly decreasing throughout the world. we examine how the consideration that a wild plant use is within the cultural tradition of a given area relates to its consumption by analysing 1) current perception and 2) past and present use of six wild plants' food-uses, of which only three are locally perceived as being part of the local tradition. research was conducted in gorbeialdea, an area in t ...201728087368
effects of herbal essential oil mixture as a dietary supplement on egg production in quail.one hundred and eighty 7-week-old laying quail were fed various diets over a 12-week period. the diets included a control diet (without essential oil mixture (eom) or antibiotics (ants)), a basal diet including eom (24 mg/kg feed), and a basal diet including an ant (avilamycin, 10 mg/kg feed). each treatment comprised 4 replications with 4 cages (15 quail per cage), amounting to 60 quail per treatment group. diets (in mash form) and water were provided for ad libitum consumption. eom consisted o ...201424587729
investigation of the antioxidant behavior of air- and freeze-dried aromatic plant materials in relation to their phenolic content and vegetative cycle.the total phenolic and flavonoid content of the aerial parts of five aromatic plants harvested at different periods was estimated, and their antioxidant capacity was evaluated. major phenolic compounds present in their extracts were determined by rp-hplc. the results demonstrated different amounts of total phenolic compounds and various degrees of antioxidant activity depending on the plant species, the time of harvest, and the drying method employed. extracts from air-dried mentha viridis l., o ...200818578534
[antioxidant properties of essential oils: autoxidation of essential oils from laurel and fennel and effects of mixing with essential oil from coriander].changes in the composition of essential oils from the seeds of laurel (laurus nobilis l.) and fennel (foeniculum vulgare mill., var. dulce thelling) and their mixture with essential oil from coriander were studied by capillary gas-liquid chromatography during storage in the dark and in light. under these conditions, essential oil of laurel retained its composition for 12 months. essential oil of fennel was rapidly oxidized in light. however, the rate of its oxidation in the dark was lower. the m ...201216358762
antifungal activity, mode of action and anti-biofilm effects of laurus nobilis linnaeus essential oil against candida spp.the present study demonstrated the antifungal potential of the chemically characterized essential oil (eo) of laurus nobilis l. (bay laurel) against candida spp. biofilm adhesion and formation, and further established its mode of action on c. albicans.201727771586
antibacterial and antibiofilm activities of laurus nobilis l. essential oil against staphylococcus aureus strains associated with oral infections.laurus nobilis l. is an aromatic herb with relevant medicinal properties due to its important chemical composition and its potential therapeutic effects. in this study, we investigate the chemical composition, the antibacterial and the antibiofilms activities of tunisian l. nobilis l. essential oils against clinical staphylococcus aureus strains.201526657812
activity, polypeptide and gene identification of thylakoid ndh complex in trees: potential physiological relevance of fluorescence assays.three evergreen (laurus nobilis, viburnum tinus and thuja plicata) and two autumnal abscission deciduous trees (cydonia oblonga and prunus domestica) have been investigated for the presence (zymogram and immunodetection) and functionality (post-illumination chlorophyll fluorescence) of the thylakoid ndh complex. the presence of encoding ndh genes has also been investigated in t. plicata. western assays allowed tentative identification of zymogram nadh dehydrogenase bands corresponding to the ndh ...201222324908
effects of essential oils from medicinal plants acclimated to benin on in vitro ruminal fermentation of andropogon gayanus grass.plants from west africa commonly used in both human and veterinary medicine contain various secondary metabolites. however, their potential in mitigating ruminal methane production has not been explored. this study examined the effects of seven essential oils (eos) from plants acclimated to benin at four dosages (100, 200, 300 and 400 mg l(-1)), on in vitro rumen microbial fermentation and methane production using andropogon gayanus grass as a substrate.201524930456
optimization of the spray application technology in bay laurel (laurus nobilis).bay laurel is an evergreen, commercially grown and expensive ornamental pot plant, which is susceptible to different pests like aphids, scale and lerp insects, thrips, caterpillars of codling moth and sooty moulds. recently, caterpillars of the mediterranean carnation leafroller (cacoecimorpha pronubana) cause more and more problems. these pests can lead to important financial losses for the growers. during summer the individual pot plants are placed on a field-container in a fairly dense config ...200920218514
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