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enhancement of murine sarcoma virus (moloney) infection in mice by guaroa virus. 19704321083
co-infection of mouse spleen cells with murine sarcoma virus and guaroa virus.enhancement of tumor induction by oncornaviruses through a dual viral infection has been described by several investigators. the mechanism(s) of this enhancement has not as yet been determined. by using a murine sarcoma virus and a bunyawera group arbovirus (guaroa virus) in an in vitro system, evidence was obtained for enhancement of the oncogenic potential of the viruses by genetic interaction with the nononcogenic virus as well as the production of increased amounts of the oncogenic virus. th ...19724336016
identification of two plaque variants of guaroa virus. 19695369730
enhancement of friend leukemia virus infection in mice by guaroa virus: quantitation and action of various oncogenic and nononcogenic viruses.previous studies have indicated that guaroa virus (gv), an arbovirus, enhanced the replication of friend leukemia virus (flv) in mice. to study further the interaction of gv and flv, different levels of flv activity were inoculated into mice. at a level of activity capable of producing limited splenic response, coinfection with gv resulted in a marked increase in spleen-foci activity, mean spleen weight, and amount of infectious virus recoverable from plasma and spleen of dually infected mice. v ...19705498601
enhancement of friend and rauscher leukemia virus replication in mice by guaroa virus. 19685658440
studies on guaroa virus. i. virus characteristics. 19676021741
studies on guaroa virus. ii. observations in mice. 19676021742
studies on guaroa virus. 3. experimental infection of burros. 19676021743
isolations of guaroa virus from anopheles (kerteszia) neivai in the pacific lowlands of colombia. 19676066225
the s rna genome segments of batai, cache valley, guaroa, kairi, lumbo, main drain and northway bunyaviruses: sequence determination and analysis.bunyaviruses have a genome comprising three segments of negative-sense rna. the smallest rna segment, s, encodes the nucleocapsid protein, n, and a nonstructural protein, nss, in overlapping reading frames. the sequences of the s genome rna segments of seven bunyaviruses (batai, cache valley, guaroa, kairi, main drain, northway and lumbo) were determined from cloned cdnas obtained using a one-step reverse transcription-pcr protocol. these sequences were compared to those of six viruses previousl ...19948126455
the bunyamwera virus nonstructural protein nss inhibits viral rna synthesis in a minireplicon system.the small (s) genomic segment of bunyamwera virus (family bunyaviridae, genus bunyavirus) encodes the nucleocapsid protein, n, and a nonstructural protein, nss, in overlapping reading frames. in order to elucidate the function of nss, we established a plasmid-based minireplicon system using mammalian cells that express large amounts of t7 rna polymerase. expression of n, the viral polymerase protein (l), and a minireplicon containing a reporter gene was sufficient to reconstitute functional viru ...200111222097
guaroa virus, a new agent isolated in colombia, south america. 195913851794
the california complex of arthropod-borne viruses and its relationship to the bunyamwera group through guaroa virus. 196214000396
virus biographies. i. growth of west nile and guaroa viruses in tissue culture.southam, chester m. (sloan-kettering institute for cancer research, new york, n.y.), frederick h. shipkey, virginia i. babcock roller bailey, and robert a. erlandson. virus biographies. i. growth of west nile and guaroa viruses in tissue culture. j. bacteriol. 88:187-199. 1964.-monolayer tissue cultures of hep 2 cells (human epidermoid carcinoma) were inoculated with guaroa or west nile viruses. at daily intervals for 4 days thereafter, these cultures were studied by (i) light microscopy of livi ...196414197886
analysis of the medium (m) segment sequence of guaroa virus and its comparison to other orthobunyaviruses.guaroa virus (grov), a segmented virus in the genus orthobunyavirus, has been linked to the bunyamwera serogroup (bun) through cross-reactivity in complement fixation assays of s segment-encoded nucleocapsid protein determinants, and also to the california serogroup (cal) through cross-reactivity in neutralization assays of m segment-encoded glycoprotein determinants. phylogenetic analysis of the s-segment sequence supported a closer relationship to the bun serogroup for this segment and it was ...200415448370
in vitro and in vivo studies of the interferon-alpha action on distinct orthobunyavirus.oropouche, caraparu, guama, guaroa and tacaiuma viruses (orthobunyavirus genus) cause human febrile illnesses and/or encephalitis. to achieve a therapeutical agent to prevent and/or treat these diseases we evaluated the antiviral action of interferon-alpha (ifn-alpha) on these orthobunyaviruses. in vitro results showed that all the studied orthobunyaviruses are susceptible to antiviral action of ifn-alpha, but this susceptibility is limited and dependent on both concentration of drug and treatme ...200717368573
arboviral etiologies of acute febrile illnesses in western south america, 2000-2007.arthropod-borne viruses (arboviruses) are among the most common agents of human febrile illness worldwide and the most important emerging pathogens, causing multiple notable epidemics of human disease over recent decades. despite the public health relevance, little is know about the geographic distribution, relative impact, and risk factors for arbovirus infection in many regions of the world. our objectives were to describe the arboviruses associated with acute undifferentiated febrile illness ...201020706628
guaroa virus infection among humans in bolivia and peru.guaroa virus (grov) was first isolated from humans in colombia in 1959. subsequent isolates of the virus have been recovered from febrile patients and mosquitoes in brazil, colombia, and panama; however, association of the virus with human disease has been unclear. as part of a study on the etiology of febrile illnesses in peru and bolivia, 14 grov strains were isolated from patients with febrile illnesses, and 3 additional cases were confirmed by igm seroconversion. the prevalence rate of grov ...201020810845
spatiotemporal analysis of guaroa virus diversity, evolution, and spread in south america.we conducted phylogeographic modeling to determine the introduction and spread of guaroa virus in south america. the results suggest a recent introduction of this virus into regions of peru and bolivia over the past 60-70 years and emphasize the need for increased surveillance in surrounding areas.025695188
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