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studies on the sero-epidemiology of endemic diseases in libya, iv. malaria.indirect fluorescent antibody studies were conducted in order to determine possible risk to libyan communities of malaria, particularly relapsing forms, as a direct result of the presence of large teams of immigrant labour. two groups of indians (100 and 81) indicated past exposure to relapsing malaria, measured by plasmodium fieldi antigen, in the range 42.0-44.0%, to recent/heavy relapsing infection (12.4-19.0%) and to recent/heavy p. falciparum infection (2.5-4.0%). a non-asian group (149) in ...19853907553
the exoerythrocytic schizonts of plasmodium fieldi. 19684234360
the influence of splenectomy on infections of plasmodium fieldi in macaca mulatta monkeys. 19734631555
observations on the relapse activity of plasmodium fieldi in the rhesus monkey. 19714994804
transmission of plasmodium fieldi by anopheles maculatus, a. stephensi, and a. balabacensis balabacensis. 19685647124
studies of the exoerythrocytic stages of simian malaria. i. plasmodium fieldi. 19676022384
determination of malarial antibodies by means of screening and differentiating antigens.4455 human sera with malarial antibodies were analysed with regard to their reactivity to screening antigens (plasmodium fieldi and p. falciparum) and to differentiating antigens (p. vivax, p. ovale and p. malariae/brasilianum). results were obtained by indirect fluorescent antibody test. the identification rate of antibodies was significantly higher with p. fieldi than with p. falciparum antigen, and was lowest for both of the screening antigens in sera with antibodies to p. ovale. the highest ...19826184910
infection and transmission studies with the n-3 strain of plasmodium fieldi in the macaca mulatta monkey.seven different anophelines--anopheles freeborni, an. dirus, an. maculatus, an. atroparvus, an. stephensi, an. albimanus, and an. quadrimaculatus--were shown to be susceptible to infection with the n-3 strain of plasmodium fieldi. transmission was obtained via the bites of an. dirus, an. stephensi, and an. maculatus mosquitoes to macaca mulatta monkeys. sporozoites dissected from an. freeborni were also shown to be infectious. anopheles dirus and an. stephensi were the most suitable mosquitoes f ...19846491849
in vitro cultivation of exoerythrocytic stages of the simian malaria parasites plasmodium fieldi and plasmodium simiovale in rhesus monkey hepatocytes.exoerythrocytic stage parasites of plasmodium fieldi and plasmodium simiovale, 2 simian malaria parasites related to the human malaria parasite plasmodium ovale, were cultured in vitro by inoculating primary cultures of hepatocytes from rhesus monkeys (macaca mulatta) with sporozoites. less than 1% of sporozoites developed into schizonts for either species. structure and size of the liver stages in both species were similar to previous in vivo descriptions, and the time required for in vitro mat ...19948195940
attempts to transmit the n-3 strain of plasmodium fieldi to aotus monkeys.aotus lemurinus griseimembra monkeys inoculated with parasitized erythrocytes of the n-3 strain of plasmodiumfieldi had transient low-density parasitemia. exoerythrocytic stages of this strain of parasite were demonstrated in sections of liver from aotus vociferans monkeys taken 8 days after the intravenous inoculation of sporozoites dissected from the salivary glands of anopheles dirus mosquitoes; no blood-stage infections were observed.19989488369
the development of exoerythrocytic stages of plasmodium inui shortti in new world monkeys.attempts are being made to adapt old world monkey malarial parasites to new world monkeys for vaccine and molecular studies. several of these (plasmodium cynomolgi berok, plasmodium fragile, and plasmodium knowlesi) grow readily but have failed to produce infective gametocytes. plasmodium gonderi and plasmodium fieldi develop in the liver after sporozoite inoculation but have failed to establish infection in the erythrocyte. anopheles dirus mosquitoes infected with plasmodium inui shortti by fee ...200312880277
plasmodium fieldi sp. nov., a new species of malaria parasite from the pigtailed macaque in malaya. 196213891114
morphology of plasmodium fieldi in different species of the genus macaca. 196414240058
plasmodium fieldi: observations on the hackeri and abi strains in macaca mulatta monkeys and mosquitoes.macaca mulatta monkeys infected with the hackeri strain of plasmodium fieldi had maximum parasite counts ranging from 1,300 to 301,320/microl. in 43 intact animals infected with the abi strain, the maximum parasite counts ranged from 672 to 57,189/microl (median = 15,100/microl); in 46 splenectomized monkeys, the maximum parasite count ranged from 660 to 350,000/microl (median = 52,245/microl). transmission through anopheles dirus mosquitoes was obtained on 11 occasions with pre-patent periods o ...200919407117
the evolution and diversity of a low complexity vaccine candidate, merozoite surface protein 9 (msp-9), in plasmodium vivax and closely related species.the merozoite surface protein-9 (msp-9) has been considered a target for an anti-malarial vaccine since it is one of many proteins involved in the erythrocyte invasion, a critical step in the parasite life cycle. orthologs encoding this antigen have been found in all known species of plasmodium parasitic to primates. in order to characterize and investigate the extent and maintenance of msp-9 genetic diversity, we analyzed dna sequences of the following malaria parasite species: plasmodium falci ...201324044894
distribution and prevalence of malaria parasites among long-tailed macaques (macaca fascicularis) in regional populations across southeast asia.plasmodium knowlesi and plasmodium cynomolgi are two malaria parasites naturally transmissible between humans and wild macaque through mosquito vectors, while plasmodium inui can be experimentally transmitted from macaques to humans. one of their major natural hosts, the long-tailed macaque (macaca fascicularis), is host to two other species of plasmodium (plasmodium fieldi and plasmodium coatneyi) and is widely distributed in southeast asia. this study aims to determine the distribution of wild ...201627590474
simian malaria in wild macaques: first report from hulu selangor district, selangor, malaysia.malaria is a vector-borne parasitic disease which is prevalent in many developing countries. recently, it has been found that plasmodium knowlesi, a simian malaria parasite can be life-threatening to humans. long-tailed macaques, which are widely distributed in malaysia, are the natural hosts for simian malaria, including p. knowlesi. the aim of the present study was to determine the prevalence of simian malaria parasites in long-tailed macaques in the district of hulu selangor, selangor, malays ...201526437652
non-human primate malaria parasites: out of the forest and into the laboratory.the study of malaria in the laboratory relies on either the in vitro culture of human parasites, or the use of non-human malaria parasites in laboratory animals. in this review, we address the use of non-human primate malaria parasite species (nhpmps) in laboratory research. we describe the features of the most commonly used nhpmps, review their contribution to our understanding of malaria to date, and discuss their potential contribution to future studies.201627748213
identification of a vir-orthologous immune evasion gene family from primate malaria parasites.the immune evasion gene family of malaria parasites encodes variant surface proteins that are expressed at the surface of infected erythrocytes and help the parasite in evading the host immune response by means of antigenic variation. the identification of plasmodium vivax vir orthologous immune evasion gene family from primate malaria parasites would provide new insight into the evolution of virulence and pathogenesis. three vir subfamilies viz. vir-b, vir-d and vir-g were successfully pcr ampl ...201424477117
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