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poly(ethylene glycol)-block-poly(ε-caprolactone) nanomicelles for the solubilization and enhancement of antifungal activity of sertaconazole.sertaconazole nitrate is a broad spectrum imidazole antifungal agent with antibacterial and anti-inflammatory properties. however, its lipophilic nature and very poor aqueous solubility limit its use in the clinic. the aim of this study was to develop and characterize poly(ethylene glycol)-block-poly(ε-caprolactone) (peg-b-pcl) polymeric nanomicelles for the solubilization and enhancement of sertaconazole antifungal activity. sertaconazole was incorporated into peg-b- pcl polymeric nanomicelles ...201424909149
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