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metabolic products of microorganisms 167. cyclopaldic acid from aspergillus duricaulis. 1. production, isolation and bioloical properties.in the course of a screening for new metabolites from fungi we isolated a substance with antimicrobial activity from cultures of aspergillus duricaulis (cbs 481.65) (tü 679). it was antagonized by putrescine, spermidine, spermine, arginine, citrulline, lysine, ornithine, in higher concentration by aspraagine and glutamine too. the effect of ethylenediaminetetraacetate on the susceptibility of streptomyces viridochromogenes (tü 57) and bacillus subtilis atcc 6051 to this antibiotic has been studi ...1978417692
[metabolic products of microorganisms. 35. asperdurin, a new antimycotic phthalide from aspergillus duricaulis]. 19883219049
spiroindole alkaloids and spiroditerpenoids from aspergillus duricaulis and their potential neuroprotective effects.six new spiroindole alkaloids (1-6) and two new spiroditerpenoids (7 and 8) were isolated from an etoac extract of aspergillus duricaulis culture media together with five known compounds. the structures of the isolated compounds were elucidated by analysis of nmr and ms data, and the absolute configurations of compounds 1-8 were confirmed by cd spectroscopic methods. all isolated compounds were evaluated for their inhibition of beta-amyloid (aβ) aggregate-induced toxicity in pc12 cells and aβ ag ...201526517152
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