| beta-naphthoflavone-inducible cytochrome p4501a1 activity in liver microsomes of the marine safi fish (siganus canaliculatus). | the cytochrome p450-dependent metabolism of benzo(a)pyrene and other xenobiotics has been investigated in liver microsomes prepared from a local marine safi fish, siganus canaliculatus. the safi fish was found to have a well-developed microsomal monooxygenase system consisting of cytochrome p450, cytochrome b5 and nadph-cytochrome c reductase. the fish microsomal enzyme system was able to metabolize benzo(a)pyrene, 7-ethoxycoumarin and 7-ethoxyresorufin. male fish were found to exhibit a higher ... | 1995 | 7503790 |
| transcriptional responses of xenobiotic metabolizing enzymes, hsp70 and na+/k+ -atpase in the liver of rabbitfish (siganus oramin) intracoelomically injected with amnesic shellfish poisoning toxin. | amnesic shellfish poisoning toxin domoic acid (da) is a marine neurotoxin that accumulates in fish and shellfish, and has been implicated to be involved in human and marine wildlife mortality. the transcriptional responses of cytochrome p-450 1a (cyp1a), glutathione s-transferase alpha (gsta), glutathione s-transferase rho (gstr), heat shock protein 70 (hsp70), and na(+)/k(+)-atpase alpha 1 (atp1a1) in the liver of rabbitfish (siganus oramin) intracoelomically injected with da, were investigated ... | 2008 | 18214893 |
| metal concentrations in green-lipped mussels (perna viridis) and rabbitfish (siganus oramin) from victoria harbour, hong kong after pollution abatement. | | 2008 | 18554668 |
| chemical composition of raw fish consumed in bahrain. | nine species (seriolina nigrofasciata, siganus canaliculatus, rhabdosargus haffara, scomberomorus commerson, liza alata, epinephelus areolatus, plectorhinchus sordidus, lethrinus nebulosus and penaeus semislcatus) of raw fish commonly consumed in bahrain were analyzed for their proximate, mineral and heavy metal content. the protein content ranged from 17.9-21.8 g/100 g, fat content from 0.80-16.1 g/100 g and energy content from 87.1-216.7 kcal/100 g. the raw fish also had high levels of sodium ... | 2008 | 18819593 |
| the use of muscle burden in rabbitfish siganus oramin for monitoring polycyclic aromatic hydrocarbons and polychlorinated biphenyls in victoria harbour, hong kong and potential human health risk. | muscle concentrations of polycyclic aromatic hydrocarbons (pahs) and polychlorinated biphenyls (pcbs) were determined in rabbitfish siganus oramin collected from victoria harbour and its vicinity, hong kong from 2004 to 2007. spatially, relatively higher levels of [summation operator]pah (1.05-4.26 microg g(-1)) and [summation operator]pcb (45.1-76.9 ng g(-1)) were determined in the central and western sites inside the harbour. temporally, upward trend of [summation operator]pah, accompanied wit ... | 2009 | 19406454 |
| postsynaptic alpha 2-adrenoceptors mediate melanosome aggregation in melanophores of the white-spotted rabbitfish (siganus canaliculatus). | the present investigation was undertaken to study the nature of neuro-melanophore junction in the white-spotted rabbit fish siganus canaliculatus. in vitro experiments using split fin preparation indicated that melanophores of s. canaliculatus are highly responsive to potassium ions and adrenergic agonists. potassium ions and the adrenergic agonists induced prompt melanosome aggregation that could be competitively blocked by yohimbine (alpha-2 specific adrenergic antagonist) and phentolamine (no ... | 2009 | 19579911 |
| a novel protein isolated from the serum of rabbitfish (siganus oramin) is lethal to cryptocaryon irritans. | the susceptibility of eight marine fish species cultured in south china were tested for infection by the parasitic ciliate, cryptocaryon irritans, via a challenge examination and an immobilization assay. all species of fish (representing six different families) that we investigated were infected by c. irritans except the rabbitfish (siganus oramin), which displayed resistance to c. irritans infection. the infection intensity of rabbitfish (0.92+/-0.97, p<0.05) was significantly lower while the i ... | 2010 | 20117218 |
| vertebrate fatty acyl desaturase with δ4 activity. | biosynthesis of the highly biologically active long-chain polyunsaturated fatty acids, arachidonic (ara), eicosapentaenoic (epa), and docosahexaenoic (dha) acids, in vertebrates requires the introduction of up to three double bonds catalyzed by fatty acyl desaturases (fad). synthesis of ara is achieved by δ6 desaturation of 182n - 6 to produce 183n - 6 that is elongated to 203n - 6 followed by δ5 desaturation. synthesis of epa from 183n - 3 requires the same enzymes and pathway as for ara, but d ... | 2010 | 20826444 |
| the serum of rabbitfish (siganus oramin) has antimicrobial activity to some pathogenic organisms and a novel serum l-amino acid oxidase is isolated. | the serum of rabbitfish (siganus oramin) has been confirmed previously to have killing effect to cryptocaryon irritans, an important marine ciliate protozoan that causes a disease referred to as "marine white spot disease". herein, we find the serum of the rabbitfish also shows antibacterial activity against both gram-positive and gram-negative bacteria and has killing effect on two other parasites: trypanosoma brucei brucei, ichthyophthirius multifiliis. results of scanning electron microscopy ... | 2011 | 21333741 |
| Histopathological liver alterations in juvenile rabbit fish (Siganus canaliculatus) exposed to light Arabian crude oil, dispersed oil and dispersant. | With the heavy transport of crude oil there is an increasing risk of a major oil spill in the Gulf waters; however, there have been few studies on the impact of oil spills and subsequent remedial action on Gulf fish. The aim of the experiment was to investigate the effects of acute exposure to water soluble fraction (WAF) of light Arabian crude oil, dispersed oil and dispersant on the liver of the juvenile rabbit fish (Siganus canaliculatus), observing several histopathological biomarkers of the ... | 2012 | 21974902 |
| the mir-33 gene is identified in a marine teleost: a potential role in regulation of lc-pufa biosynthesis in siganus canaliculatus. | as the first marine teleost demonstrated to have the ability to biosynthesize long-chain polyunsaturated fatty acids (lc-pufa) from c18 pufa precursors, rabbitfish siganus canaliculatus provides a good model for studying the regulatory mechanisms of lc-pufa biosynthesis in teleosts. here the potential roles of mir-33 in such regulation were investigated. the mir-33 gene was identified within intron 16 of the gene encoding sterol regulatory element-binding protein 1 (srebp1), an activator of lc-p ... | 2016 | 27640649 |
| antibacterial efficacy of recombinant siganus oramin l-amino acid oxidase expressed in pichia pastoris. | siganus oraminl-amino acid oxidase is a novel natural protein (named sr-laao) isolated from serum of the rabbitfish (s. oramin), which showed antibacterial activity against both gram-positive and gram-negative bacteria and had a lethal effect on the parasites cryptocaryon irritans, trypanosoma brucei brucei and ichthyophthirius multifiliis. in order to test whether recombinant sr-laao (rsr-laao) produced by the eukaryotic expression system also has antimicrobial activity, the yeast pichia pastor ... | 2014 | 25238719 |
| siganus oramin recombinant l-amino acid oxidase is lethal to cryptocaryon irritans. | a novel antimicrobial and antiparasitic protein (app/sr-laao) isolated from serum of the rabbitfish (siganus oramin) was confirmed to be lethal to cryptocaryon irritans, an important marine parasitic ciliate that causes marine white spot disease in a variety of wild and cultured fish. in this study, a recombinant sr-laao (rsr-laao) was expressed on a large scale in escherichia coli rosetta-gami™(de3)plyss cells. rsr-laao was expressed as an inactive form in the inclusion bodies. the 3-(4,5-dimet ... | 2013 | 24113573 |
| long-chain polyunsaturated fatty acid biosynthesis in the euryhaline herbivorous teleost scatophagus argus: functional characterization, tissue expression and nutritional regulation of two fatty acyl elongases. | both the spotted scat scatophagus argus and rabbitfish siganus canaliculatus belong to the few cultured herbivorous marine teleost, however, their fatty acyl desaturase (fad) system involved in long-chain polyunsaturated fatty acid (lc-pufa) biosynthesis is different. the s. argus has a △6 fad, while the rabbitfish has △4 and △6/△5 fads, which were the first report in vertebrate and marine teleost, respectively. in order to compare the characteristics of elongases of very long-chain fatty acids ... | 2016 | 27050407 |
| cloning, functional characterization and nutritional regulation of δ6 fatty acyl desaturase in the herbivorous euryhaline teleost scatophagus argus. | marine fish are generally unable or have low ability for the biosynthesis of long-chain polyunsaturated fatty acids (lc-pufa) from c18 pufa precursors, with some notable exceptions including the herbivorous marine teleost siganus canaliculatus in which such a capability was recently demonstrated. to determine whether this is a unique feature of s. canaliculatus or whether it is common to the herbivorous marine teleosts, lc-pufa biosynthetic pathways were investigated in the herbivorous euryhalin ... | 2014 | 24594899 |
| four amino acid residues influence the substrate chain-length and regioselectivity of siganus canaliculatus δ4 and δ5/6 desaturases. | although ω3- and ω6- desaturases have been well studied in terms of substrate preference and regiospecificity, relatively little is known about the membrane-bound, "front-end" long chain fatty acid desaturases, such as ∆4, δ5 or δ6 desaturases. the first vertebrate ∆4 desaturase was recently identified in the marine teleost fish siganus canaliculatus (s. canaliculatus), which also possesses a bifunctional δ5/6 desaturase. these two long chain polyunsaturated fatty acid desaturases are very diffe ... | 2014 | 24477708 |
| differential inhibition of xenobiotic-metabolizing carboxylesterases by organotins in marine fish. | the hydrolytic metabolism of xenobiotics in the liver of two tropical marine fish, siganus canaliculatus and acanthopagrus latus, was found to be catalyzed by both microsomal and cytosolic carboxylesterases; the latter forms were more active than the former. remarkably greater efficiency of s. canaliculatus for p-nitrophenylacetate hydrolysis was attributed to manyfold higher v(max) and lower k(m) values of hepatic microsomal and cytosolic carboxylesterases of s. canaliculatus as compared with t ... | 2000 | 10903822 |
| enhanced production of docosahexaenoic acid in mammalian cells. | docosahexaenoic acid (dha), one of the important polyunsaturated fatty acids (pufa) with pharmaceutical and nutraceutical effects, may be obtained through diet or synthesized in vivo from dietary a-linolenic acid (ala). however, the accumulation of dha in human body or other mammals relies on the intake of high dose of dha for a certain period of time, and the bioconversion of dietary ala to dha is very limited. therefore the mammalian cells are not rich in dha. here, we report a new technology ... | 2014 | 24788769 |
| morphological, ultrastructural, and molecular description of unicapsula fatimae n. sp. (myxosporea: trilosporidae) of whitespotted rabbitfish (siganus canaliculatus) in omani waters. | investigations regarding the parasite fauna of wild whitespotted rabbitfish (siganus canaliculatus) park, 1797 revealed white, spherical, loosely attached cysts measuring 896 (375-1406) μm in diameter in the inner endothelial wall of the esophagus and stomach. mature spores inside these cysts corresponded to the original description of spores belonging to the genus unicapsula davis, 1924. unicapsula fatimae n. sp. spores were 6.23 (5.60-6.60) μm in length and 6.80 (6.12-7.39) μm in width. the le ... | 2016 | 26693719 |
| morphological and molecular identification of hysterothylacium longilabrum sp. nov. (nematoda: anisakidae) and larvae of different stages from marine fishes in the south china sea. | a new ascaridoid nematode hysterothylacium longilabrum sp. nov. collected from the intestine and stomach of the marine fishes siganus fuscescens (houttuyn) and siganus canaliculatus (park) (perciformes: siganidae) in the south china sea is described and illustrated. the new species differs from its congeners by the unusually long lips, the very short intestinal caecum and relatively long ventricular appendix (ratio of intestinal caecum to ventricular appendix, 1:2.38-5.50), the long spicules (1. ... | 2012 | 22461007 |
| the status of the diplosentidae (acanthocephala: palaeacanthocephala) and a new family of acanthocephalans from australian wrasses (pisces: labridae). | the status and composition of the diplosentidae tubangui et masiluñgan, 1937 are reviewed. the type species of the type genus, diplosentis amphacanthi tubangui et masiluñgan, 1937 from siganus canaliculatus (park, 1797) in the philippines, is concluded to have been described inaccurately in supposedly possessing only two cement glands and lemnisci enclosed in a membranous sac. the species is almost certainly very close to species of neorhadinorhynichus yamaguti, 1939 and sclerocollum schmidt et ... | 2001 | 11817452 |