| homeostasis as regulated by activated macrophage. ii. lps of plant origin other than wheat flour and their concomitant bacteria. | in order to seek a macrophage-activating substance, lipopolysaccharide (lps) of plant origin other than that of wheat flour was surveyed. a large amount of lps (10-100 micrograms/g) was detected in laminaria japonica (kelp), curcuma longa (turmeric), undaria pinnatifida and other substances. since concomitant bacteria possibly existing in root of farm products can be considered to contribute to lps of plant origin, a count was taken of bacterial cells both dead and alive. this count revealed tha ... | 1992 | 1525958 |
| [study on iodine intake by the japanese. report 1. digestibility of iodine from the seaweed undaria pinnatifida]. | | 1986 | 3573393 |
| nutritive value of marine algae laminaria japonica and undaria pinnatifida. | the chemical composition, that is crude proteins, fats, carbohydrates, cellulose, ashes, minerals and nucleic acids were determined in two commercially available marine algae: laminaria japonica and undaria pinnatifida. the energetic value and energetic share of proteins, fats and carbohydrates were calculated. the results were discussed in terms of importance of marine algae in human diet. | 1995 | 7898578 |
| purification and characterization of a new agarase from a marine bacterium, vibrio sp. strain jt0107. | a marine bacterial strain that decomposes the cell walls of some seaweeds, including a laminaria sp. and undaria pinnatifida, has been isolated from seawater. this strain has been classified to the genus vibrio. one of the enzymes which the bacteria secreted into the culture medium was isolated and purified 45-fold from the culture fluid by a combination of ammonium sulfate precipitation and successive rounds of anion-exchange column chromatography. purified protein migrated as a single band (m( ... | 1993 | 8517750 |
| inhibition of icosanoid production in mc/9 mouse mast cells by n-3 polyunsaturated fatty acids isolated from edible marine algae. | the effects of two polyunsaturated fatty acids, 18:4n-3 and 16:4n-3 purified from the marine algae, undaria pinnatifida and ulva pertusa, on icosanoid production in mc/9 mouse mast cells were assessed. both fatty acids suppressed the production of leukotriene b4 (ltb4), leukotriene c4 (ltc4), and 5-hydroxyeicosatetraenoic acid (5-hete). the order of the suppressive activity for the two marine algae-derived fatty acids and three other common polyunsaturated fatty acids was as follows; 22:6n-3 = 1 ... | 1998 | 9720225 |
| dietary modulation of bacterial fermentative capacity by edible seaweeds in rats. | the effect of edible seaweeds [nori (porphyra tenera) and wakame (undaria pinnatifida)] on the modulation of colonic microbiota was studied in adult male wistar rats. each alga was fed to rats as the only source of dietary fiber and compared with cellulose. after 12 days, animals were sacrificed and cecal contents used as inoculum to ferment lactulose, citrus pectin, cellulose, nori, and wakame in vitro. dietary treatment did not affect food intake or food efficiency, yet alga caused a significa ... | 2001 | 11368652 |
| an hplc method for the quantification of sterols in edible seaweeds. | this study presents an hplc method for the quantification of sterols in edible seaweeds. sterols were identified by hplc/mass spectrometry (hplc-ms) in positive apci mode. the samples were saponified by refluxing with 1 m ethanolic koh, and the non-saponifiable fraction was extracted with hexane. sterols were quantified by hplc with uv detection (hplc-uv), on a 15 x 0.4 cm kromasil 100 c(18) 5 micro m column (mobile phase 30:70 v/v methanol:acetonitrile; fl ow rate 1.2 ml/min; column temperature ... | 2004 | 15103705 |
| novel antiviral fucoidan from sporophyll of undaria pinnatifida (mekabu). | structural characterization and antiviral activities of fucoidan from sporophyll of undaria pinnatifida (mekabu) was examined. the fucoidan was composed of fucose and galactose with an approximately ratio of 1.0:1.1. degree of substitution of sulfate was 0.72 and its apparent molecular weight was 9,000. methylation analyses showed that fucoidan had various sugar linkages, and revealed that the fucoidan might have complicated structure. this fucoidan showed potent antiviral activities against her ... | 2004 | 15340195 |
| [purification and analysis of polysaccharides from the caudex of undaria pinnatifida]. | to isolate polysaccharides with hot water from the caudex of undaria pinnatifida, and precipitate with ethanol. the protein in polysaccharides was removed by sevage way. deae-52 and sephadex g-200 column chromatography were used to isolate and purification polysaccharides, three purified polysaccharides f2, f3 and f4 were obtained. it was identified that they were homogeneity. the ultraviolet spectrum showed there was no proteins and nucleic acids in f2, f3 and f4. through thin-layer chromatogra ... | 2005 | 16447868 |
| antiviral activity of undaria pinnatifida against herpes simplex virus. | the major component of an aqueous extract of the seaweed undaria pinnati fi da has been identified previously as a galactofucan (gfs), a sulfated polysaccharide. the galactofucan was partially purified and the material tested in this study is 75% pure galactofucan sulfate. gfs was evaluated for antiviral activity against 32 clinical strains of herpes simplex virus (hsv): 14 strains of hsv-1 and 18 strains of hsv-2. twelve strains (four hsv-1 and eight hsv-2) were resistant to acyclovir (acv-r) a ... | 2004 | 15305315 |
| antihypertensive effects of undaria pinnatifida (wakame) peptide on blood pressure in spontaneously hypertensive rats. | we examined the angiotensin i-converting enzyme (ace) inhibitory activity and antihypertensive effect of the hot water extract of wakame, undaria pinnatifida. ten dipeptides were isolated from the extract by several steps of chromatography, and their amino acid sequences were tyr-his, lys-trp, lys-tyr, lys-phe, phe-tyr, val-trp, val-phe, ile-tyr, ile-trp, and val-tyr. both single administration and repeated oral administration of synthetic tyr-his, lys-tyr, phe-tyr, and ile-tyr significantly dec ... | 2004 | 15135150 |
| marine bacteria associated with the korean brown alga, undaria pinnatifida. | several marine bacterial strains were isolated from undaria pinnatifida (miyok in korean). sixty-six strains were isolated on r2a agar media at 10 degrees and identified by a phylogenetic analysis of the 16s rrna gene sequences. they were grouped into 10 different sequence types based on the initial sequence analysis of the 5' domain of the gene (approximately 500 bp). full sequences of 16s rrna gene were obtained from one strain in each sequence type and the species-affiliation was determined u ... | 2006 | 17205052 |
| isolation and characterization of a fucoidan-degrading marine bacterium. | fucoidan, a mixture of sulfated fucose-containing polysaccharides, was prepared from the algal bodies of cladosiphon okamuranus (class phaeophyceae, order chordariales, family chordariaceae) with a yield of 2.0% of the wet weight of the alga. to obtain enzymes that digest the fucoidan, we screened bacteria in the guy contents of the sea cucumber stichopus japonicus for their ability to decrease the fucoidan in their culture media, and successfully isolated one bacterial strain that could decreas ... | 2003 | 14735911 |
| antitumor activity and immune response of mekabu fucoidan extracted from sporophyll of undaria pinnatifida. | we showed that fucoidan, extracted from dietary seaweed, could inhibit tumor growth. however, the mechanism of mekabu (sporophyll of undaria pinnatifida) fucoidan antitumor activity and how it enhances the immune response remains unknown. | 2003 | 12929574 |
| effect of undaria pinnatifida (wakame) on the development of cerebrovascular diseases in stroke-prone spontaneously hypertensive rats. | 1. we showed that a nutritional factor was able to attenuate the development of hypertension and its related diseases in stroke-prone spontaneously hypertensive rats (shrsp). in the present study, the effect of wakame, an edible brown seaweed, on the development of stroke was examined in shrsp. 2. we studied the treatment with 5% (w/w in a diet) wakame powder in salt-loaded (0.5% nacl in drinking water) shrsp. salt-loaded animals treated with 5% cellulose or kaolin were used as controls. wakame ... | 2003 | 12542452 |
| antihypertensive effects of hydrolysates of wakame (undaria pinnatifida) and their angiotensin-i-converting enzyme inhibitory activity. | the angiotensin-i-converting enzyme (ace) inhibitory and antihypertensive activities of wakame hydrolysates have been investigated in several studies. | 2002 | 12464726 |
| [studies on evaluation of natural products for antiviral effects and their applications]. | in the search for novel antiviral molecules from natural products, we have discovered various antiviral molecules with characteristic mechanisms of action. scopadulciol (sdc), isolated from the tropical medicinal plant scoparia dulcis l., showed stimulatory effects on the antiviral potency of acyclovir (acv) or ganciclovir (gcv). this effect of sdc was exerted via the activation of viral thymidine kinase (hsv-1 tk) and, as a result, an increase in the cellular concentration of the active form of ... | 2008 | 18176057 |
| gfs, a preparation of tasmanian undaria pinnatifida is associated with healing and inhibition of reactivation of herpes. | we sought to assess whether gfs, a proprietary preparation of tasmanian undaria pinnatifida, has effects on healing or re-emergence of herpetic infections, and additionally, to assess effects of gfs in vitro. undaria is the most commonly eaten seaweed in japan, and contains sulphated polyanions and other components with potential anti-viral activity. herpes simplex virus type 1 (hsv-1) infections have lower reactivation rates and herpes type 2 (hsv-2) infections have lower incidence in japan tha ... | 2002 | 12443533 |
| angiotensin i-converting enzyme inhibitory peptides derived from wakame (undaria pinnatifida) and their antihypertensive effect in spontaneously hypertensive rats. | seven kinds of angiotensin i-converting enzyme (ace) inhibitory peptides were isolated from the hydrolysates of wakame (undaria pinnatifida) by protease s "amano" (from bacillus stearothermophilus) by using three-step high-performance liquid chromatography (hplc) on a reverse-phase column. these peptides were identified by amino acid composition analysis, sequence analysis, and liquid chromatography-mass spectrometry (lc-ms), as val-tyr (ic(50) = 35.2 microm), ile-tyr (6.1 microm), ala-trp (18.8 ... | 2002 | 12358510 |
| heavy metal contamination in the seaweeds of the venice lagoon. | the concentrations of heavy metals (fe, zn, cu, cd, ni, pb, cr, as) were determined in seven seaweeds of environmental and commercial relevance (ulva rigida c. ag., gracilaria gracilis (stackhouse) steentoft, l. irvine and farnham, porphyra leucosticta thuret, grateloupia doryphora (montagne) howe., undaria pinnatifida (harv.) suringar, fucus virsoides j. agardh, cystoseira barbata (good. et wood.) ag.) collected in four sampling sites in the lagoon of venice, in spring and autumn 1999. metals w ... | 2002 | 11999620 |
| growth-inhibitory effect of a fucoidan from brown seaweed undaria pinnatifida on plasmodium parasites. | the present study was undertaken to investigate the inhibitory effects of fucoidan, a sulfated polysaccharide isolated from the edible brown seaweed undaria pinnatifida, on the growth of plasmodium parasites. in order to assess the anti-malarial activity of fucoidan, growth inhibition activities were evaluated using cultured plasmodium falciparum parasites in vitro and on plasmodium berghei-infected mice in vivo. fucoidan significantly inhibited the invasion of erythrocytes by p. falciparum mero ... | 2009 | 18791738 |
| dietary fish oil and undaria pinnatifida (wakame) synergistically decrease rat serum and liver triacylglycerol. | japanese eating habits are characterized by the consumption of various food materials such as cereals, vegetables, fish, shellfish, marine algae and meat. therefore, properties of functional substances in food materials may be enhanced or lessened by the combination of various food materials. in the present study, we examined how the combination of wakame and fish containing polyunsaturated fatty acids, which are typical japanese food materials, affected rat lipid metabolism. rats were fed one o ... | 2002 | 11925471 |
| new loliolide derivatives from the brown alga undaria pinnatifida. | seven carotenoid metabolites including five loliolide derivatives have been isolated from the brown alga undaria pinnatifida, including three new compounds. structures of these compounds were confirmed by spectroscopic analyses and literature data. | 2002 | 11809066 |
| identification of an antihypertensive peptide from peptic digest of wakame (undaria pinnatifida). | a peptide fraction having activity against angiotensin i-converting enzyme (ace) was separated from the peptic digest of protein prepared from wakame (undaria pinnatifida) by ion-exchange chromatographies and gel-filtration. fractions with high ace inhibitory activity were combined and further chromatographed on a reverse-phase column to yield four tetrapeptides with ace inhibitory properties. these tetrapeptides were identified by sequence analysis and fast atom bombardment mass spectrometry as ... | 2000 | 11091100 |
| the bioavailability of magnesium from wakame (undaria pinnatifida) and hijiki (hijikia fusiforme) and the effect of alginic acid on magnesium utilization of rats. | the bioavailability of magnesium from wakame and hijiki, and the effects of alginic acid on absorption of dietary magnesium were examined in five groups of rats fed either control, wakame, hijiki, aw (containing the same amount of alginate as in the wakame) and ah (containing the same amount of alginate as in the hijiki) diets, and animals fed a low magnesium diet (lmg) (twentieth amount of magnesium in the original mineral mixtures as the control). food intake and body weight gain were decrease ... | 1999 | 10517285 |
| hepatic fatty acid oxidation enzyme activities are stimulated in rats fed the brown seaweed, undaria pinnatifida (wakame). | the activities of hepatic enzymes involved in fatty acid synthesis and oxidation were compared in rats fed diets containing different proportions of dried powder of the brown seaweed, undaria pinnatifida (wakame). rats were fed diets containing 0, 0.5, 1.0, 2. 0, 5.0 and 10 g/100 g of dried wakame powder. experimental diets were adjusted to provide consistent amounts of most nutrients, but mineral concentrations were not standardized. after the 21-d feeding period, serum and liver triacylglycero ... | 1999 | 9915891 |
| content and characteristics of vitamin b12 in some seaweeds. | the vitamin b12 (b12) content in seven species of seaweed that are consumed frequently in hokkaido, japan, was microbiologically measured using escherichia coli 215. asakusanori (porphyra tenera), maruba-amanori (porphyra suborbiculata) and akaba-gin-nansou (rhodo-glossum pulcherum) showed higher b12 content than the other species, although the content varied greatly among samples in the same species. a bioautography on a thin-layer plate holding a mixture of silica gel and cellulose, differenti ... | 1996 | 9089476 |
| in vitro fermentation by human faecal bacteria of total and purified dietary fibres from brown seaweeds. | the in vitro degradation of dietary fibre from three brown seaweeds (himanthalia elongata, laminaria digitata and undaria pinnatifida) was studied, using human faecal flora. two sets of fibre were tested: (1) total algal fibres extracted from the whole algae, mainly composed of alginates, and (2) purified fibres (sulphated fucans, na-alginates and laminarans) representative of those contained in the whole brown algae. mannuronate, one algal component, was also investigated. substrate disappearan ... | 1996 | 8785203 |
| identification of heterogenous antimutagenic activities in the extract of edible brown seaweeds, laminaria japonica (makonbu) and undaria pinnatifida (wakame) by the umu gene expression system in salmonella typhimurium (ta1535/psk1002). | a significant antimutagenic activity was found in the hot water-soluble extract from a common edible brown alga, laminaria japonica (makonbu in japanese) which showed suppressive effects on umu gene expression of the sos response against dna damage in salmonella typhimurium (ta1535/psk1002). the extract showed a drastic antimutagenic activity against 2-acetylaminofluorene (2-aaf)- or 3-amino-1,4-dimethyl-5h-pyrido[4,3-b]indole (trp-p-1)-induced mutagenesis which requires liver-metabolizing enzym ... | 1993 | 7692279 |
| poor fermentability of "mekabu" (sporophyll of undaria pinnatifida) alginic acid in batch culture using pig cecal bacteria. | sodium alginate, mannuronic acid-rich and guluronic acid-rich fractions were prepared from "mekabu" (sporophyll of undaria pinnatifida). the production of short-chain fatty acids such as acetic, propionic and n-butyric acids from these fractions in mini-scale batch culture using pig cecal bacteria was studied, and the gas released from the culture was monitored. the volume of released gas corrected for blank value decreased in the order: glucose (a reference substrate) > guluronic acid-rich frac ... | 1995 | 7562111 |
| study of a cardiotonic fraction from an extract of the seaweed. undaria pinnatifida. | | 1981 | 6265957 |
| [determination of mg and zn contents of naruto "wakame" (undaria pinnatifida)]. | the contents of mg and zn in the sea-weed "wakame" were determined and compared at different growth stages, in different parts, for different root cultivation intervals, and in processed foods. the results obtained were as follows: 1. mg (2.09-2.60 g/100 g) and zn (8.00-10.76 mg/100 g) contents were independent of growth stage with the exception of zn (29.00-35.78 mg/100 g) in the natural young "wakame". 2. the mineral contents of leaves, stipes, fruiting bodies and rhizoids of "wakame" at diffe ... | 1990 | 2255117 |
| digestibility and energy availability of wakame (undaria pinnatifida) seaweed in japanese. | the digestibilities of nutrients and energy in wakame were measured in healthy adult males. a test diet was given for 5 days after 5 days on a basal diet which supplied 40 g/day of protein and 45 kcal/kg/day of energy. the test diet was identical with the basal diet except that wakame was incorporated. digestibility was calculated by the difference of fecal output between the test period and the basal period. however the digestibility of its nutrient component was found to be different at each i ... | 1991 | 1956127 |
| the role of nk cells in antitumor activity of dietary fucoidan from undaria pinnatifida sporophylls (mekabu). | fucoidan from mekabu (sporophyll of undaria pinnatifida), a dietary alga, exerts antitumor activity possibly through enhancing the immune response. the present report describes the effects of dietary mekabu fucoidan on the tumor growth of mouse a20 leukemia cells and on t cell-mediated immune responses in t cell receptor transgenic (do-11 - 10 - tg) mice. the animals were fed with a diet containing 1% mekabu fucoidan (0.034 +/- 0.003 g/mouse/day) for 10 days and subcutaneously (s. c.) inoculated ... | 2006 | 17054048 |
| suppression of th2 immune responses by mekabu fucoidan from undaria pinnatifida sporophylls. | we demonstrated that mekabu fucoidan obtained from undaria pinnatifida (up) sporophylls augments the type 1 t-helper (th1) cell response in normal balb/c mice. in this study, we examined the effects of the fucoidan of mekabu on the type 2 t-helper (th2) response in bronchoalveolar lavage fluid (balf) after ovalbumin (ova) aerosol challenge. | 2005 | 15970637 |
| fucoxanthin from edible seaweed, undaria pinnatifida, shows antiobesity effect through ucp1 expression in white adipose tissues. | mitochondrial uncoupling protein 1 (ucp1) is usually expressed only in brown adipose tissue (bat) and a key molecule for metabolic thermogenesis to avoid an excess of fat accumulation. however, there is little bat in adult humans. therefore, ucp1 expression in tissues other than bat is expected to reduce abdominal fat. here, we show reduction of abdominal white adipose tissue (wat) weights in rats and mice by feeding lipids from edible seaweed, undaria pinnatifida. clear signals of ucp1 protein ... | 2005 | 15896707 |
| effect of brown seaweed lipids on fatty acid composition and lipid hydroperoxide levels of mouse liver. | brown seaweed lipids from undaria pinnatifida (wakame), sargassum horneri (akamoku), and cystoseira hakodatensis (uganomoku) contained several bioactive compounds, namely, fucoxanthin, polyphenols, and omega-3 polyunsaturated fatty acids (pufa). fucoxanthin and polyphenol contents of akamoku and uganomoku lipids were higher than those of wakame lipids, while wakame lipids showed higher total omega-3 pufa content than akamoku and uganomoku lipids. the levels of docosahexaenoic acid (dha) and arac ... | 2011 | 21405010 |
| fucoxanthin induces apoptosis and enhances the antiproliferative effect of the ppargamma ligand, troglitazone, on colon cancer cells. | the effect of fucoxanthin, from the edible seaweed undaria pinnatifida on viability of colon cancer cells and induction of apoptosis was investigated. fucoxanthin remarkably reduced the viability of human colon cancer cell lines, caco-2, ht-29 and dld-1. furthermore, treatment with fucoxanthin induced dna fragmentation, indicating apoptosis. the dna fragmentation in caco-2 cells treated with 22.6 microm fucoxanthin for 24 h was 10-fold higher than in the control. fucoxanthin suppressed the level ... | 2004 | 15535974 |
| the suppressive effect of mekabu fucoidan on an attachment of cryptosporidium parvum oocysts to the intestinal epithelial cells in neonatal mice. | the present study was done to investigate the effects of fucoidan and de-sulfated fucoidan isolated from the sporophyll of undaria pinnatifida on the c. parvum adhesion to the cultured human intestinal cells and on the c. parvum infection in neonatal mice. the c. parvum adhesion to human intestinal 407 cells was significantly suppressed by a low dose (1 micro g/ml) of mekabu fucoidan (1 micro g/ml) (approx. 20.5 oocysts, p<0.0001), but not by de-sulfated fucoidan (approx. 138.2 oocysts), as comp ... | 2007 | 17157323 |
| degradation of the seaweed wakame (undaria pinnatifida) by a composting process with the inoculation of bacillus sp. hr6. | disposal of the seaweed wakame (undaria pinnatifida) by inoculating the halotolerant bacterium bacillus sp. hr6 was examined in an experimental scale composting system. strain hr6 was effective in initiating the composting process of wakame, and there was a rapid increase in temperature to over 54.9-55.7 degrees c after 18-20 h. the composting process of wakame could be carried out despite a high nacl content, 28.2 mg/g, although lower salinity resulted in a shorter lag time and higher weight re ... | 2007 | 17629245 |
| isolation of two anti-inflammatory and one pro-inflammatory polyunsaturated fatty acids from the brown seaweed undaria pinnatifida. | two anti-inflammatory omega-3 polyunsaturated fatty acids (pufas) of stearidonic acid (sa) and eicosapentaenoic acid (epa) and one pro-inflammatory omega-6 pufa of arachidonic acid (aa) were isolated from the edible brown seaweed undaria pinnatifida. sa was active against mouse ear inflammation induced by phorbol myristate acetate, with ic50 values of 160, 314, and 235 microg per ear for edema, erythema, and blood flow, respectively. epa was also active against edema, erythema, and blood flow, w ... | 2007 | 17665931 |
| defensive effects of a fucoidan from brown alga undaria pinnatifida against herpes simplex virus infection. | fucoidan, a sulfated polysaccharide isolated from an edible brown alga undaria pinnatifida, was previously shown to be a potent inhibitor of the in vitro replication of herpes simplex virus type 1 (hsv-1). hsv-1 is a member of herpes viruses that cause infections ranging from trivial mucosal ulcers to life-threatening disorders in immunocompromised hosts. in the in vivo conditions, the replication of hsv-1 is controlled under the immunoresponse coordinated by both the innate and adaptive immune ... | 2008 | 18068106 |
| [introduction and establishment processes of marine species: a study case with the japanese brown kelp undaria pinnatifida]. | the number of biological introductions has increased since the 1970's and is now considered as the second major cause of the biodiversity erosion, after fragmentation or disappearance of habitat. beyond the threat they represent for the ecosystem equilibrium, introduced species are interesting models to study fundamental issues in ecology and evolution like the processes of dispersal and adaptation to novel environments. in this context, species introduced over a large geographic range and spect ... | 2007 | 18157078 |
| low bioavailability of dietary epoxyxanthophylls in humans. | epoxyxanthophylls (epoxide-containing xanthophylls), a group of carotenoids, are ubiquitously distributed in edible plants. among them, neoxanthin in green leafy vegetables and fucoxanthin in brown algae have been reported to exhibit an antiproliferative effect on several human cancer cells in vitro. however, there is little information about the intestinal absorption and metabolic fate of dietary epoxyxanthophylls in humans. to estimate the intestinal absorption of neoxanthin and fucoxanthin in ... | 2008 | 18186952 |
| effects of the brown seaweed undaria pinnatifida on erythematous inflammation assessed using digital photo analysis. | the brown seaweed undaria pinnatifida (harvey) suringar produced potent inhibition of erythematous inflammation assessed using digital photo analysis. the analysis technique was validated by laser speckle flowgraphy and blood vessel contraction. the methanol extract suppressed erythema by 50% when applied within 1 h before or 15 min after application of phorbol myristate acetate. erythema reduction to half-maximal values took 12 h with the extract, compared with 25 h with the vehicle. the blade ... | 2008 | 18384198 |
| isolation and characterization of marine bacterial strain degrading fucoidan from korean undaria pinnatifida sporophylls. | in spite of an increasing interest in fucoidans as biologically active compounds, no convenient commercial sources with fucoidanase activity are yet available. a marine bacterial strain that showed confluent growth on a minimal medium containing fucoidan, prepared from korean undaria pinnatifida sporophylls, as the sole carbon source was isolated and identified based on a 16s rdna sequence analysis as a strain of sphingomonas paucimobilis, and named sphingomonas paucimobilis pf-1. the strain dep ... | 2008 | 18467852 |
| selenium nanoparticles fabricated in undaria pinnatifida polysaccharide solutions induce mitochondria-mediated apoptosis in a375 human melanoma cells. | selenium nanoparticle (nano-se) is a novel se species with novel biological activities and low toxicity. in the present study, we demonstrated a simple method for synthesis of size-controlled nano-se by adding undaria pinnatifida polysaccharides to the redox system of selenite and ascorbic acid. a panel of four human cancer cell lines was shown to be susceptible to nano-se, with ic(50) values ranging from 3.0 to 14.1 microm. treatment of a375 human melanoma cells with the nano-se resulted in dos ... | 2008 | 18805679 |
| elastin peptide receptor-directed monocyte chemotactic polysaccharides derived from seaweed sporophyll and from infectious fungus. | we discovered that a seaweed sporophyll-derived polysaccharide of brown alga, wakame (undaria pinnatifida) bound to monocytes and attracted them in vitro and in vivo. physicochemical properties, affinity to a lectin-bead column and sugar composition of the chemotactic polysaccharide indicated this molecule to be a highly sulfated fucogalactan. we then identified the monocyte receptor of the sulfated fucogalactan as the elastin peptide receptor by prophylactic inhibition of the binding and the ch ... | 2008 | 18976701 |
| anti-inflammatory activities of methanol extracts from various seaweed species. | thirty-seven species of common seaweeds from the coast of korea were screened for anti-inflammatory activity methanol extracts of the seaweeds were tested against mouse ear edema and erythema induced by phorbol myristate acetate. at 40 mg ml(-1) of extract, edema was strongly suppressed by the seaweeds undaria pinnatifida and ulva linza, with relative inhibition of 85 and 84%, respectively these two seaweeds also showed the greatest suppression of erythema, with inhibition of 78 and 70%, respect ... | 2008 | 19195382 |
| bioactive phenols in algae: the application of pressurized-liquid and solid-phase extraction techniques. | a new extraction technique based on the off-line combination of pressurized-liquid with solid-phase extraction (ple-spe) is described. the method was used for the extraction of bioactive phenolic acids (protocatechuic, p-hydroxybenzoic, 2,3-dihydroxybenzoic, chlorogenic, vanillic, caffeic, p-coumaric, salicylic acid), cinnamic acid and hydroxybenzaldehydes (p-hydroxybenzaldehyde, 3,4-dihydroxybenzaldehyde, vanillin) from in vitro culture of two freshwater algae (anabaena doliolum and spongiochlo ... | 2010 | 19410410 |
| anti-edema effects of brown seaweed (undaria pinnatifida) extract on phorbol 12-myristate 13-acetate-induced mouse ear inflammation. | the brown seaweed undaria pinnatifida (harvey) suringar is used in traditional medicine to treat fever, urination problems, lumps and swelling, and as a dietary supplement for post-childbirth women. we examined the anti-inflammatory activities of the seaweed. the methanol extract of the seaweed was active against mouse ear edema induced by phorbol myristate acetate (pma), with an ic(50) of 10.3 mg/ml. the extract reduced the edema to a half-maximal level when applied at the concentration of 40 m ... | 2009 | 19507279 |
| understanding the association of escherichia coli with diverse macroalgae in the lagoon of venice. | recent studies provided evidence that the macroalga cladopohora in lakes hosts associated escherichia coli, with consequences on the environmental and human health. we expanded these investigations to other macroalgae (ulva spp., sargassum muticum and undaria pinnatifida) widespread in the lagoon of venice (italy). attached e. coli were abundant, accounting up to 3,250 cfu gram(-1) of alga. macroalgal-associated isolates belonged to all e. coli phylogroups, including pathogenic ones, and to esch ... | 2015 | 26043415 |
| virucidal activity of polysaccharide extracts from four algal species against herpes simplex virus. | herpes simplex virus types 1 and 2 (hsv-1, hsv-2) infections are common, but can cause serious infections in neonates and the immunocompromised. drugs currently used to treat cutaneous or genital hsv infections are effective in limiting disease, but the emergence of drug resistant viruses in immunocompromised individuals can be problematic. while the prophylactic oral treatment with antiviral drugs can reduce virus shedding and transmission, there is a need for topical microbicides that have the ... | 2009 | 19576248 |
| inhibition of proliferation of a hepatoma cell line by fucoxanthin in relation to cell cycle arrest and enhanced gap junctional intercellular communication. | fucoxanthin is one of the most abundant carotenoids found in undaria pinnatifida and has been shown to inhibit tumor proliferation in vitro. however, the mechanisms underlying the anti-cancer effects of fucoxanthin are unclear. in this study, we hypothesized that fucoxanthin may cause cell cycle arrest and enhance gap junctional intercellular communication (gjic) in sk-hep-1 human hepatoma cells. data revealed that fucoxanthin (1-20microm) strongly and concentration-dependently inhibited the pro ... | 2009 | 19737546 |
| a 4-week repeated oral dose toxicity study of fucoidan from the sporophyll of undaria pinnatifida in sprague-dawley rats. | fucoidan is extracted from brown seaweeds, which can have anti-coagulant, antithrombotic, antitumor, and antiviral activities. however, detailed studies on the toxicology of fucoidan have not been performed. here we tested the toxicity of fucoidan in sprague-dawley rats. fucoidan (1350mg/kg bw/day for 4 weeks) did not induce statistically significant differences in groups matched by gender with respect to body weight, ophthalmoscopy, urinalysis, hematology, and histopathology. fucoidan did not c ... | 2010 | 19903507 |
| genotoxicity studies on fucoidan from sporophyll of undaria pinnatifida. | the sulfated seaweed extract, fucoidan, has anticoagulant, antithrombotic, and antiviral activities. despite extensive work on the biological activities of fucoidan, detailed studies on the genotoxicity of fucoidan from sporophyll of undaria pinnatifida sources have not been tested before. the objective of this study was to investigate the genotoxicity effects of fucoidan extracted from sporophyll of u. pinnatifida using a test battery of three different methods. in a reverse mutation assay usin ... | 2010 | 20138103 |
| anticoagulating activities of low-molecular weight fuco-oligosaccharides prepared by enzymatic digestion of fucoidan from the sporophyll of korean undaria pinnatifida. | in spite of their potential as biologically active compounds, the high molecular mass and viscous natures of fucoidans have hampered their applications especially as a therapeutic agent. herein the fucoidan-degrading enzyme activities were partially purified from the cultured cells of sphingomonas paucimobilis pf-1 mainly by ammonium sulfate precipitation. this enzyme preparation degraded fucoidans from the korean undaria pinnatifida sporophyll into several low-molecular weight fuco-oligosacchar ... | 2010 | 20191353 |
| beneficial effects of undaria pinnatifida ethanol extract on diet-induced-insulin resistance in c57bl/6j mice. | this study was performed to evaluate the beneficial effect of undaria pinnatifida ethanol extract (uefx) on insulin resistance in diet-induced obese mice. a high-fat diet was supplemented with the uefx at 0.69% (wt/wt) dose, which contains an equivalent amount of 0.02% fucoxanthin (wt/wt), or with fx at 0.02% (wt/wt) dose in diet. after 9 weeks, both uefx supplement significantly lowered the amount of visceral fat, the size of adipocyte, the fasting blood glucose concentration, the plasma insuli ... | 2010 | 21146577 |
| converting carbohydrates extracted from marine algae into ethanol using various ethanolic escherichia coli strains. | marine algae, which make up about 80% of the world's living organisms, contain many energy sources, such as sugars and lipids. therefore, the possibility of utilizing structural carbohydrates from marine algae for bioethanol production has been studied. in order to obtain monosaccharides, undaria pinnatifida, chlorella vulgaris, and chlamydomonas reinhardtii were used for the saccharification experiments. the pretreatment was carried out by dilute acid hydrolysis and enzymatic treatment. to find ... | 2011 | 21286944 |
| anti-glycation properties of the aqueous extract solutions of dried algae products and effect of lactic acid fermentation on the properties. | the antioxidant and anti-glycation properties in aqueous extract solutions (aess) of 11 dried algae products were investigated. aess of brown algae ecklonia kurome (kurome) and ecklonia stolonifera (tsuruarame) showed a strong dpph radical-scavenging capacity and fe-reducing power with high total phenolic compound content. on the other hand, superoxide anion radical-scavenging capacities of porphyra sp. (iwanori, red alga), sporophyll of undaria pinnatifida (mekabu, brown alga), and gelidiaceae ... | 2016 | 26304454 |
| fucoidan from undaria pinnatifida induces apoptosis in a549 human lung carcinoma cells. | fucoidan, a sulfated polysaccharide, has various biological activities, such as anticancer, antiangiogenic and antiinflammatory effects; however, the mechanisms of action of fucoidan on anticancer activity have not been fully elucidated. the anticancer effects of fucoidan from undaria pinnatifida on a549 human lung carcinoma cells were examined. treatment of a549 cells with fucoidan resulted in potent antiproliferative activity. also, some typical apoptotic characteristics, such as chromatin con ... | 2011 | 21452391 |
| anti-listerial activity of four seaweed essential oils against listeria monocytogenes. | listeria monocytogenes is one of the most virulent types of bacteria and causes severe foodborne illness, such as listeriosis. because this pathogen has become resistant to sanitizers and other disinfectants that are used to clean utensils and surfaces during food processing, it poses a serious threat to the food industry. | 2016 | 27679700 |
| bioactive metabolites from guignardia sp., an endophytic fungus residing in undaria pinnatifida. | to isolate new and/or bioactive constituents from etoac extract of liquid culture of endophyte guignardia sp. from the leaves of undaria pinnatifida (harv.) sur. | 2012 | 23302536 |
| anti-obesity and anti-diabetic effects of fucoxanthin on diet-induced obesity conditions in a murine model. | fucoxanthin, a characteristic carotenoid of brown algae, has been reported to exert an anti-diabetic effect in an obese murine model. wakame (undaria pinnatifida), an edible seaweed, is rich in fucoxanthin. this study examined the anti-obesity and anti-diabetic effects of fucoxanthin-rich wakame lipids (wls) on high fat (hf) diet-induced obesity in mice. mice were fed a high fat control (hfc) or normal fat control (nfc) diet for 10 weeks. the hf diet-fed group was administered a hf diet containi ... | 2009 | 21475918 |
| antiobesity effects of undaria lipid capsules prepared with scallop phospholipids. | based on previous research findings, a capsule was developed containing n-3 polyunsaturated fatty acid rich scallop phospholipids (pls) with an incorporation of brown seaweed (undaria pinnatifida) lipids (uls) containing fucoxanthin. the antiobesity effects of the capsules were evaluated with an animal model using 3-wk-old male kk-a(y) mice. each group received different combinations of lipid (ul, pl, ul + pl, or ul + pl capsule) either incorporated into the diet or into drinking water. animals ... | 2011 | 21535684 |
| in vitro cytotoxic effect of ethanol extract prepared from sporophyll of undaria pinnatifida on human colorectal cancer cells. | brown seaweed undaria pinnatifida (harvey) suringar is popular as a foodstuff, and used for medical care in east asian countries. the major components of this seaweed are shown to benefit hypertension and hyperlipidemia, and considered to reduce the risks of infarction and ischemic diseases. furthermore, the intake of dietary fiber of seaweeds is considered to prevent the production and proliferation of cancer in the gastrointestinal tract. the direct effect of an ethanol extract prepared from u ... | 2011 | 21604310 |
| isolation and characterization of microbulbifer species 6532a degrading seaweed thalli to single cell detritus particles. | to reduce the volume of seaweed wastes and extract polysaccharides, seaweed-degrading bacteria were isolated from drifting macroalgae harvested along the coast of toyama bay, japan. sixty-four bacterial isolates were capable of degrading "wakame" (undaria pinnatifida) thallus fragments into single cell detritus (scd) particles. amongst these, strain 6532a was the most active degrader of thallus fragments, and was capable of degrading thallus fragments to scd particles within a day. although the ... | 2011 | 21681519 |
| leuconostoc miyukkimchii sp. nov., isolated from brown algae (undaria pinnatifida l.) kimchi in korea. | a gram-positive, non-motile and non-spore forming lactic acid bacterium, designated strain m2t, was isolated from fermented brown algae (undaria pinnatifida l.) kimchi in south korea. cells of the isolate were facultative anaerobic ovoids and showed catalase- and oxidase-negative reactions. growth of strain m2t was observed at 4-35 -¦c and at ph 5.0-9.0. the g+c content of the genomic dna was 42.5 mol%. phylogenetic analysis based on 16s rrna gene sequences indicated that strain m2 belonged to t ... | 2011 | 21705441 |
| An Antithrombotic Fucoidan, Unlike Heparin, Does Not Prolong Bleeding Time in a Murine Arterial Thrombosis Model: A Comparative Study of Undaria pinnatifida sporophylls and Fucus vesiculosus. | The antithrombotic activities and bleeding effects of selected fucoidans (source from either Undaria pinnatifida sporophylls or from Fucus vesiculosus) have been compared with heparin in the ferric chloride-induced arterial thrombus mouse model. Thrombosis was induced by applying 5% ferric chloride for 3?min on the carotid artery region of Balb/c mouse. Five minutes prior to thrombus induction, mice were infused through the tail vein with either saline (control) or polysaccharides. Either fucoid ... | 2011 | 22084059 |
| Sulfated polysaccharides from brown seaweeds Saccharina japonica and Undaria pinnatifida: isolation, structural characteristics, and antitumor activity. | During the last decade brown seaweeds attracted much attention as a source of polysaccharides, namely laminarans, alginic acids, and sulfated polysaccharides-fucoidans, with various structures and biological activities. In this study, sulfated polysaccharides were isolated from brown seaweeds Saccharina japonica (formerly named Laminaria) and Undaria pinnatifida and their antitumor activity was tested against human breast cancer T-47D and melanoma SK-MEL-28 cell lines. The sulfated polysaccharid ... | 2011 | 22024567 |
| Determination of Water-Soluble Arsenic Compounds in Commercial Edible Seaweed by LC-ICPMS. | This paper reports arsenic speciation in edible seaweed (from the Galician coast, northwestern Spain) produced for human consumption. Chondrus crispus , Porphyra purpurea , Ulva rigida , Laminaria ochroleuca , Laminaria saccharina , and Undaria pinnatifida were analyzed. The study focused on arsenosugars, the most frequently occurring arsenic species in algae. As(III) and As(V) were also determined in aqueous extracts. Total arsenic in the samples was determined by microwave digestion and ... | 2011 | 22082352 |
| algibacter wandonensis sp. nov., isolated from sediment around a brown algae (undaria pinnatifida) reservoir. | a gram-stain-negative, non-flagellated, rod-shaped bacterial strain able to move by gliding, designated ws-my22(t), was isolated from sediment around a brown algae reservoir located on wando in south korea. it grew optimally at 25 °c, at ph 7.0-8.0 and in the presence of 2.0 % (w/v) nacl. phylogenetic trees based on 16s rrna gene sequences showed that strain ws-my22(t) clustered coherently with the type strains of algibacter lectus and algibacter undariae. it exhibited sequence similarity of 99. ... | 2013 | 23996835 |
| discriminant analysis of undaria pinnatifida production areas using trace elemental analysis. | increasingly, attention is being paid to declaring the origin of agricultural and marine products after the advent of the bovine spongiform encephalopathy (bse; commonly known as mad-cow disease). the display of the production centers on u. pinnatifida has been required in japan since 2006. as an example of testing in another marine product, near-infrared spectra (nir) and trace elemental analysis of u. pinnatifida are proven effective methods for discriminating production centers by us and food ... | 2010 | 20490259 |
| toxicological evaluation of fucoidan from undaria pinnatifidain vitro and in vivo. | the potential toxicity of fucoidan from undaria pinnatifida was investigated in vitro and in vivo. by the ames test, fucoidan showed no mutagenicity up to 500 microl/plate, and inhibited the mutagenicity induced by 4-nitro-quinoline-1-oxide, by up to 71%, compared with controls. in the bone marrow micronucleus test, fucoidan, at all levels tested, did not change the micronucleated polychromatic erythrocyte percentage ratio in mouse bone marrow cells. as an acute in vivo toxicity test, fucoidan f ... | 2010 | 20578121 |
| improved composting of undaria pinnatifida seaweed by inoculation with halomonas and gracilibacillus sp. isolated from marine environments. | composting of the undaria pinnatifida (wakame) seaweed was conducted after inoculation with 6×10(8) cfu g(-1)halomonas sp. aw4 and the alginate-degrading bacterium gracilibacillus sp. a7. inoculation with strains a7 and aw4 resulted in 27.8% and 24.7% degradation of u. pinnatifida dry mass after 168 h, whereas only 17.5% degradation occurred in the uninoculated control. the c/n ratio decreased in the a7 and aw4 inoculated compost by 7.0% and 9.2% after 72 h, but increased by 11.5% in the control ... | 2010 | 21145233 |
| protective effects of mekabu aqueous solution fermented by lactobacillus plantarum sanriku-su7 on human enterocyte-like ht-29-luc cells and dss-induced murine ibd model. | most wakame undaria pinnatifida, a brown algae, products are made from the frond portion. in this study, the polysaccharide content and antioxidant property of aqueous extract solutions (aess) of the four parts (frond: wakame, stem of the frond: kuki-wakame, sporophyll: mekabu, and kuki-mekabu) of wakame were investigated. polysaccharide content was high in both the wakame and mekabu. superoxide anion (o2(-)) radical-scavenging capacities were high in the mekabu. these aess could be fermented by ... | 2017 | 27535691 |
| induction of the superoxide anion radical scavenging capacity of dried 'funori'gloiopeltis furcata by lactobacillus plantarum s-su1 fermentation. | to understand the beneficial properties of edible algae obtained from the north-eastern (sanriku) satoumi region of japan, the antioxidant properties of hot aqueous extract solutions (aes) obtained from 18 dried algal products were determined. the samples included 4 ceratophyllum demersum (matsumo), 5 undaria pinnatifida (wakame), 5 laminaria japonica (kombu), and 2 each of gloiopeltis furcate (funori) and g. tenax (funori). of these products, the total phenolic content and fe-reducing power wer ... | 2015 | 26110834 |
| citeromyces matritensis m37 is a salt-tolerant yeast that produces ethanol from salted algae. | algae are referred to as a third-generation biomass for ethanol production. however, salinity treatment is a problem that needs to be solved, because algal hydrolysates often contain high salt. here, we isolated the salt-tolerant ethanol-producing yeast citeromyces matritensis m37 from the east coast of miura peninsula in japan. this yeast grew under osmotic stress conditions (20% nacl or 60% glucose). it produced 6.55 g/l ethanol from ypd medium containing 15% nacl after 48 h, and the ethanol a ... | 2017 | 27835736 |
| bioethanol production from brown seaweed, undaria pinnatifida, using nacl acclimated yeast. | strain improvement of pichia angophorae kctc 17574 was successfully carried out for bioethanol fermentation of seaweed slurry with high salt concentration. p. angophorae kctc 17574 was cultured under increasing salinity from five practical salinity unit (psu, ‰) to as high as 100 psu for 723 h. the seaweed, undaria pinnatifida (sea mustard, miyuk), was fermented to produce bioethanol using high-salt acclimated yeast. the pretreatment of u. pinnatifida was optimized using thermal acid hydrolysis ... | 2013 | 23361184 |
| winogradskyella undariae sp. nov., a member of the family flavobacteriaceae isolated from a brown algae reservoir. | a novel bacterial strain, designated ws-my5(t), capable of degrading a variety of polysaccharides was isolated from a brown algae (undaria pinnatifida) reservoir at wando in the south sea, south korea. strain ws-my5(t) was found to grow optimally at 30 °c, at ph 7.0-7.5 and in the presence of 2 % (w/v) nacl. a neighbour-joining phylogenetic tree based on 16s rrna gene sequences showed that strain ws-my5(t) falls within the clade comprising winogradskyella species, clustering with the type strain ... | 2013 | 23839058 |
| evaluation of innate immune stimulating activity of polysaccharides using a silkworm (bombyx mori) muscle contraction assay. | in silkworm larvae, the mature form of paralytic peptide (pp), an insect cytokine, is produced from pro-pp in association with activation of innate immune responses, resulting in slow muscle contraction. we utilized this reaction, muscle contraction in silkworms coupled with innate immunity stimulation, to quantitatively measure the innate immune stimulating activity of various natural polysaccharides. β-glucan of gyrophora esculenta (ge-3), fucoidan from sporophyll of undaria pinnatifida, and c ... | 2012 | 22622018 |
| nutritional and toxicological importance of macro, trace, and ultra-trace elements in algae food products. | the content of 5 macro elements (na, k, ca, mg, and p), 6 trace elements (fe, mn, zn, cu, se, and i), and 4 ultra-trace elements (as, pb, cd, and hg) in 34 edible dried seaweed products of brown algae (laminaria sp., undaria pinnatifida, and hizikia fusiforme) and red algae (porphyra sp.) originated from china, japan, and korea and bought by retail in germany was determined. the content of these elements was analyzed by spectrometric methods (icp-aes, icp-ms, hgaas, and cvaas). assuming a daily ... | 2007 | 17994690 |
| arsenosugars in raw and cooked edible seaweed: characterization and bioaccessibility. | the aim of this study was to examine arsenic species contents in raw and cooked edible seaweed and the bioaccessibility (maximum soluble concentration in gastrointestinal medium) of arsenosugars (glycerol ribose, phosphate ribose, sulfonate ribose, and sulfate ribose). for the analysis, a new chromatographic separation was developed in anion exchange, coupled with thermooxidation-hydride generation-atomic fluorescence spectrometry. an in vitro digestion (pepsin, ph 2; pancreatin-bile extract, ph ... | 2005 | 16131152 |
| development of new efficient method for isolation of phenolics from sea algae prior to their rapid resolution liquid chromatographic-tandem mass spectrometric determination. | the extraction of phenolic compounds from 4 different sea algae samples, three brown algae (cystoseira abies-marina, c. abies-marina grinded under cryogenic conditions with liquid nitrogen, undaria pinnatifida and sargassum muticum) and one red algae (chondrus crispus) via solid phase extraction using micro-elution solid-phase extraction (μ-spe) plate method was studied. prior to μ-spe, 50mg of algae with 80% methanol mixture was extracted in hyphenated series by various extraction techniques, s ... | 2017 | 28012309 |
| polyunsaturated fatty acids in various macroalgal species from north atlantic and tropical seas. | in this study the efficacy of using marine macroalgae as a source for polyunsaturated fatty acids, which are associated with the prevention of inflammation, cardiovascular diseases and mental disorders, was investigated. | 2011 | 21696609 |
| capacity of edible seaweeds to modify in vitro starch digestibility of wheat bread. | the capacity of two species of edible seaweeds (wakame, undaria pinnatifida and chondrus, chondrus crispus) to modify the rate of white bread starch digestibility by an in vitro digestion system, as well as glucose retardation index and apparent viscosity were studied. both algae showed different effect on glucose retardation index. while wakame did not make difficult dialysis of glucose, it only retained 2.50 +/- 2.99% to respect a negative control. chondrus impaired the diffusion of a 28.70 +/ ... | 2002 | 11890047 |
| protective effect of the edible brown alga ecklonia stolonifera on doxorubicin-induced hepatotoxicity in primary rat hepatocytes. | as part of our efforts to isolate anti-hepatotoxic agents from marine natural products, we screened the ability of 14 edible varieties of korean seaweed to protect against doxorubicin-induced hepatotoxicity in primary rat hepatocytes. | 2014 | 24628384 |
| dietary algae and hiv/aids: proof of concept clinical data. | dietary algae have been reported to decrease hiv viral fusion/entry and replication and increase immune response, suggesting that regular consumption of algae by people in japan, korea, and chad could be an important factor in their relatively low hiv/aids rates. five antiretroviral-naïve people with hiv (three females, two males; five african americans) living in columbia sc participated in the phase i study of acute toxicity. subjects were randomly assigned to 5 g day(-1) brown seaweed (undari ... | 2011 | 22661829 |
| the consumption of seaweed as a protective factor in the etiology of breast cancer: proof of principle. | daily consumption of seaweed has been proposed as a factor in explaining lower postmenopausal breast cancer (bc) incidence and mortality rates in japan. this clinical trial assessed the impact of introducing seaweed- to non-seaweed-consuming american postmenopausal women. fifteen healthy postmenopausal women were recruited for a 3-month single-blinded placebo controlled clinical trial; five had no history of bc (controls) and ten were bc survivors. participants ingested ten capsules daily (5 g d ... | 2012 | 23678231 |
| purification and characterization of a fucoidanase (fnase s) from a marine bacterium sphingomonas paucimobilis pf-1. | the search for enzyme activities that efficiently degrade marine polysaccharides is becoming an increasingly important area for both structural analysis and production of lower-molecular weight oligosaccharides. in this study, an endo-acting fucoidanase that degrades miyeokgui fucoidan (mf), a sulfated galactofucan isolated from the sporophyll (called miyeokgui in korean) of undaria pinnatifida, into smaller-sized galactofuco-oligosaccharides (1000-4000 da) was purified from a marine bacterium, ... | 2015 | 26193285 |
| free radical scavenging effect of diospyros kaki, laminaria japonica and undaria pinnatifida. | diospyros kaki folium, laminaria japonica thallus and undaria pinnatifida thallus have been used traditionally in korea to promote maternal health. the scavenging activity against dpph (1,1-diphenyl-2-picrylhydrazyl) radicals of the methanol extracts of these plants were investigated. the extract of d. kaki was found to be the most potent, with an ic(50) value of 0.11 mg/ml. | 2002 | 12490237 |
| effects of dietary fermented seaweed and seaweed fusiforme on growth performance, carcass parameters and immunoglobulin concentration in broiler chicks. | this study was conducted to investigate the effects of brown seaweed (undaria pinnatifida) by-product and seaweed fusiforme (hizikia fusiformis) by-product supplementation on growth performance and blood profiles including serum immunoglobulin (ig) in broilers. fermentation of seaweeds was conducted by bacillus subtilis and aspergillus oryzae. in a 5-wk feeding trial, 750 one-d-old broiler chicks were divided into 5 groups, and were assigned to the control diet or experimental diets including co ... | 2014 | 25050025 |
| formosa undariae sp. nov., isolated from a reservoir containing the brown algae undaria pinnatifida. | a strain of gram-staining-negative, aerobic, non-flagellated, non-gliding and rod-shaped bacteria, designated ws-my3(t), was isolated from a brown algae reservoir in south korea. strain ws-my3(t) grew optimally at 25 °c, at ph 7.0-8.0 and in the presence of 2.0-3.0 % (w/v) nacl. phylogenetic trees based on 16s rrna gene sequences showed that strain ws-my3(t) fell within the cluster comprising the type strains of species of the genus formosa, clustering coherently with the type strains of formosa ... | 2013 | 23749280 |
| mekabu fucoidan: structural complexity and defensive effects against avian influenza a viruses. | fucoidan from the sporophyll (mekabu) of brown seaweed undaria pinnatifida (wakame) is interesting due to its various biological activities. mekabu fucoidan (mw ∼ 9 kda) of this study (mf) was previously isolated and characterized by chemical and separation methods including gpc and methylation analysis (lee, hayashi, hashimoto, nakano, & hayashi, 2004). it was found that this fucoidan composed of partially sulphated (ds ∼ 0.72) fucose and galactose at approximately equal amounts. methylation an ... | 2014 | 25037398 |
| anti-hsv1 activity of brown algal polysaccharides and possible relevance to the treatment of alzheimer's disease. | herpes simplex virus type 1 (hsv1) induces the formation of the characteristic abnormal molecules of alzheimer's disease (ad) brains, beta-amyloid, and abnormally phosphorylated, ad-like tau (p-tau). formation of these molecules is inhibited by treatment with the antiviral agent acyclovir (acv), which prevents viral dna replication. a totally different mechanism of antiviral action against herpes simplex viruses is shown by sulfated fucans. the antiviral activity of sulfated fucans from five bro ... | 2015 | 25583021 |
| anti-influenza a virus characteristics of a fucoidan from sporophyll of undaria pinnatifida in mice with normal and compromised immunity. | undaria pinnatifida, an edible brown alga, contains fucoidan (fuc), a sulfated polysaccharide, that inhibited the in vitro replication of influenza a virus, and stimulated both innate and adaptive immune defense functions in virus-infected mice. in the present study, the effects of oral administration of fuc were evaluated on influenza virus infection in immunocompetent and immunocompromised mice, where the efficacy of fuc was demonstrated in reducing viral replication, decreasing weight loss an ... | 2013 | 23376164 |
| draft genome sequence of lactobacillus plantarum mpl16, a wakame-utilizing immunobiotic strain isolated from swine feces. | the genome of the immunomodulatory lactobacillus plantarum mpl16, a strain able to ferment wakame (undaria pinnatifida), is described here. the reads were assembled into contigs with a total size 3,278,495 bp. the genome information will be useful for further specific genetic studies of this strain that evaluate its immunomodulatory and biotechnological properties. | 2017 | 28280008 |
| draft genome sequence of lactobacillus plantarum tl2766, a strain with the ability to ferment wakame. | the genome sequence of lactobacillus plantarum tl2766, a strain with the ability to ferment wakame (undaria pinnatifida), is described here. the reads were assembled into contigs, with a total size of 3,310,195 bp. the genome information will be useful for further specific genetic studies of this strain and for its biotechnological applications. | 2016 | 27881548 |
| tuning polyelectrolyte multilayer structure by exploiting natural variation in fucoidan chemistry. | fucoidan is a sulfated polysaccharide that is extracted primarily from seaweed. the polymer contains a natural variation in chemistry based upon the species of seaweed from which it is extracted. we have used two different fucoidans from two different seaweed species (fucus vesiculosus - fv; and undaria pinnatifida - up) as polyanions for the formation of polysaccharide-based polyelectrolyte multilayers (pems), to determine if the chemistry of different fucoidans can be chosen to fine-tune the s ... | 2015 | 25599229 |
| algal fucoidan, unlike heparin, has thrombolytic activity in a murine arterial thrombosis model. | thrombolytic effects of fucoidans were investigated in the fecl3-induced arterial thrombus mouse model and compared with heparin and tissue plasminogen activator (t-pa). thrombosis model was made by applying 5% fecl3 on the carotid artery of a balb/c mouse. twenty minutes after complete occlusion, a couple of test agents including fucoidan were infused into each mouse group with various doses intravenously, before measuring the time to reperfusion. the occluded arteries were reperfused 37.5 ± 12 ... | 2012 | 22576287 |