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complementarity between rna dimerization elements favors formation of functional heterozygous murine leukemia viruses.the cis-elements that direct packaging and dimerization of retroviral rnas overlap, and it has been suggested that dimerization is required for rna packaging. this also implies that heterodimerization would be necessary for co-packaging and recombination. moreover, co-packaging of distinct rnas may be reduced if incapable of heterodimerizing. in this study, we have designed a novel two-vector rescue system in which co-packaging and interstrand transfer are necessary for transduction. thus, the r ...200415518822
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