Publications

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the significance of the spores of the basidiomycetes (mushrooms and their allies) in bronchial asthma and allergic rhinitis.the role of basidiospores in the allergic diathesis is poorly understood. dialyzed extracts of agaricus campestris, coprinus micaceus, fuligo septica, lycoperdon perlatum, scleroderma lycoperdoides, ustilago maydis, and sooty mold were prepared from fresh spores. the study group consisted of 100 patients with asthma and 100 patients with allergic rhinitis. these 200 patients had symptoms occurring during october and november. all were intradermally skin tested with the seven extracts at concentr ...19854037433
new bioactive natural products from coprinus micaceus.chemical studies on the crude methanolic extract of coprinus micaceus, collected from the canadian prairie region, have resulted in the isolation of two new natural products, micaceol (1), a sterol and (z,z)-4-oxo-2,5-hetpadienedioic acid (2). compound 2 was isolated for the first time as a natural product. structures of these new compounds were established with the aid of extensive nmr spectroscopic studies. compound 1 has shown anti-bacterial activity against corynebacterium xerosis and staphy ...200617393652
inversion of 5s ribosomal rna genes within the genus coprinus.in the basidiomycete fungus coprinus cinereus, the 5s ribosomal rna (rrna) genes are found in the rdna repeat which encodes the other three rrnas (18s, 5.8s, and 26s), and all genes are transcribed in the same direction (cassidy et al. 1984). to facilitate examination of the rrna gene organization in additional species, we developed a method to permit determination of the direction of transcription of the rrna genes using crude preparations of genomic dna. we used this method to determine the or ...19872835172
localization of acid phosphatase activity in the basidia of coprinus micaceus.gill lamellae from the young fruiting bodies of the basidiomycete coprinus micaceus possess cytoplasmic particles with cytochemically demonstrable acid phosphatase activity; they are presumed to be lysosomes.19734736880
comparison of the interleukin-1β-inducing potency of allergenic spores from higher fungi (basidiomycetes) in a cryopreserved human whole blood system.spores from basidiomycete fungi (basidiospores) are highly prevalent in the atmosphere of urban and rural settings. studies have confirmed their potential to affect human health as allergens. less is known about their potential to serve as stimuli of the innate immune system and induce proinflammatory reactions.201424356469
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