| [prolonged storage of fungal culture collections on agarized media]. | the study of the efficacy of storage of 300 fungal cultures on agarized media with repeated passages showed that the survival level of the fungi stored with this method may serve an additional biological characteristics for some species: penicillium chrysogenum, penicillium sclerotiorum and others. when the fungi were stored on agarized media with repeated passages for a prolonged period of time, there were observed lower levels of sporulation, sclerotia formation and pigmentation in some cultur ... | 1980 | 7356295 |
| azaphilones with endothelin receptor binding activity produced by penicillium sclerotiorum: taxonomy, fermentation, isolation, structure elucidation and biological activity. | a series of azaphilones produced by penicillium sclerotiorum (xenova culture collection number x11853) active in assays for the detection of antagonists of the endothelin-a (eta) and endothelin-b (etb) receptors has been identified. the series includes two novel sclerotiorin analogues, (8s,8 alpha-r)-7-deacetyl-1,o8,8,8a-tetrahydro-7-epi-sclerotiorin, 1, and its 5-dechloro analogue, 2. it also includes 5-chloroisorotiorin, 6, previously unreported as a natural product, in addition to the major p ... | 1995 | 7592055 |
| sclerotiorine, c(20)h(20)o(5)cl, a chlorine-containing metabolic product of penicillium sclerotiorum van beyma. | | 1940 | 16747272 |
| filamentous fungi associated with mosquito larvae (diptera: culicidae) in municipalities of the brazilian amazon. | several species of the family culicidae are important vectors of diseases in humans and other animals. immature stages are filter-feeders of organic particulate matter and microorganisms. studies on microbial diversity can contribute to the discovery of new substances that can be used in the pharmaceutical industry for food or for biological control. the aim of this study was to isolate and identify the fungi associated with culicidae larvae found in different habitats (natural and artificial), ... | 2009 | 19618051 |
| a taxonomic and phylogenetic revision of the penicillium sclerotiorum complex. | the morphological concept of penicillium sclerotiorum (subgenus aspergilloides) includes strains with monoverticillate, vesiculate conidiophores, and vivid orange to red colony colours, with colourful sclerotia sometimes produced. multigene phylogenetic analyses with the nuclear ribosomal internal transcribed spacer (its) region, cytochrome c oxidase subunit 1 (cox1), β-tubulin (bena), translation elongation factor 1-α (tef1-α), and calmodulin (cmd), reveal that the p. sclerotiorum morphospecies ... | 2011 | 22308047 |
| the influence of sodium nitrate concentration on the metabolism of penicillium sclerotiorum van beyma. | | 1944 | 16747745 |
| sclerotiose-a polysaccharide metabolic product of penicillium sclerotiorum van beyma. | | 1943 | 16747623 |
| the influence of halide concentration on the metabolism of penicillium sclerotiorum van beyma. | | 1943 | 16747595 |
| penicillium sclerotiorum catalyzes the conversion of herbertenediol into its dimers: mastigophorenes a and b. | herbertenediol was subjected to biotransformation by penicillium sclerotiorum. spectral data analysis of the converted metabolites revealed that the neurotrophic active compounds, mastigophorenes a and b, dimeric to the substrate were formed. | 2005 | 15684532 |
| carotene production by penicillium sclerotiorum. | | 1957 | 13435903 |
| degradation of cyanogenic glycosides by lactobacillus plantarum strains from spontaneous cassava fermentation and other microorganisms. | strains of lactobacillus plantarum, leuconostoc mesenteroides, candida tropicalis and penicillium sclerotiorum were screened for 19 enzymatic activities using the commercial kit api zym (bio mérieux). this activity was compared to the ability of degrading the toxic cyanogenic glycosides amygdalin, linamarin, and linseed cyanogens (a mixture of linustatin and neolinustatin). good correlation between the beta-glucosidase activity found in the api zym screening and the ability to degrade the cyanog ... | 1999 | 10634708 |
| the contribution of moulds and yeasts to the fermentation of 'agbelima' cassava dough. | agbelima, a fermented cassava meal widely consumed in ghana, togo and benin, is produced by fermenting grated cassava with one of several types of traditional cassava dough inoculum. during fermentation a smooth textured sour dough is produced, the toxicity of cassava is reduced and there is a build up of volatile aroma compounds. four types of inocula were included in the present investigation. in one type moulds were found to form a dominant part of the microbiota, the species present being pe ... | 1997 | 9351208 |
| [effect of various light sources on carotenoid production by penicillium sclerotiorum]. | | 1965 | 5871136 |
| penicilazaphilone c, a new antineoplastic and antibacterial azaphilone from the marine fungus penicillium sclerotiorum. | two azaphilonidal derivatives [penicilazaphilones b (1) and c (2)], have been isolated from the fermented products of marine fungus strain penicillium sclerotiorum m-22, penicilazaphilones c was a new compound. the compound's structures were identified by the analysis of spectroscopic data including 1d and 2d nmr techniques ((1)h-nmr, (13)c-nmr, cosy, hmqc, and hmbc). biological evaluation revealed that penicilazaphilones b and c showed selective cytotoxicity against melanoma cells b-16 and huma ... | 2016 | 27605109 |
| sequential fungal fermentation-biotransformation process to produce a red pigment from sclerotiorin. | the fungus penicillium sclerotiorum produces sclerotiorin, an orange compound closely related to the useful food coloring pigments produced by monascus species. the high productivity, together with several biological activities reported for sclerotiorin highlights its potential application in food industry. in this work, sclerotiorin was obtained as the major metabolite produced in liquid fermentation by p. sclerotiorum standing for 30% of the fungal dry extract. modulation of sclerotiorin color ... | 2016 | 27211658 |
| influence of physical and chemical characteristics of wine grapes on the incidence of penicillium and aspergillus fungi in grapes and ochratoxin a in wines. | the incidence of filamentous fungi and toxin levels in grapes and wines varies depending on the variety of grapes, the wine region, agricultural practices, weather conditions, the harvest and the winemaking process. in this sense, the objective of this study was to evaluate the diversity of aspergillus and penicillium fungi isolated from wine grapes of the semi-arid tropical region of brazil, evaluate the presence of ochratoxin a (ota) in the experimental wine and verify if there is a correlatio ... | 2017 | 27792949 |
| screening filamentous tropical fungi for their nutritional potential as sources of crude proteins, lipids and minerals. | the use of fungal and yeast biomass in foodstuff, either as supplements or as major ingredients in formulations is an area of growing interest for the modern food industry. the aim of this study was to evaluate the nutritional potential of biomasses obtained from filamentous fungi penicillium sclerotiorum, penicillium janthinellum, rhizopus stolonifer and syncephalastrum racemosum. biomasses presented 26-37% of total proteins, 1.7-3.5% of lipids and 4.6-9.1% of ashes. the humidity level reached ... | 2010 | 21339148 |
| purification and characterization of a novel and unique ginsenoside rg1-hydrolyzing ß-d-glucosidase from penicillium sclerotiorum. | in this paper, a novel and unique ginsenoside rg(1)-hydrolyzing ß-d-glucosidase from penicillium sclerotiorum was isolated, characterized, and generally described. the ß-glucosidase is an ~180 kda glycoprotein with pi 6.5, and consists of four identical subunits of ~40 kda. the ß-glucosidase was active in a narrow ph range (4-5) and at relatively high temperature (60-70°c). the optimal activity against p-nitrophenyl-ß-d-glucopyranoside (pnpg) was as follows: ph 4.5 and temperature 65°c. under th ... | 2011 | 21297118 |
| azaphilone and isocoumarin derivatives from the endophytic fungus penicillium sclerotiorum psu-a13. | two new azaphilone derivatives, penicilazaphilones a (1) and b (2), and one new isocoumarin, penicilisorin (3), together with six known compounds were isolated from the endophytic fungus penicillium sclerotiorum psu-a13. their structures were identified by analysis of spectroscopic data. the antimicrobial activity against staphylococcus aureus, candida albicans and cryptococcus neoformans as well as the inhibitory effect on human immunodeficiency virus (hiv)-1 integrase and protease were examine ... | 2010 | 20686255 |
| quorum sensing as a method for improving sclerotiorin production in penicillium sclerotiorum. | quorum sensing has been extensively studied in the bacterial kingdom but little is known about it in filamentous fungi. gamma-butyrolactones have been established as quorum sensing molecules in gram-negative bacteria (as acyl-homoserine lactones) and gram-positive bacteria (as a-factor) and they are present in many filamentous fungi (e.g. as butyrolactone i in aspergillus terreus). this study investigates possible role of multicolic acid (and related derivates) as quorum sensing molecule(s) in p ... | 2010 | 20438771 |
| cell-associated acid beta-xylosidase production by penicillium sclerotiorum. | in recent decades, beta-xylosidases have been used in many processing industries. in this work, the study of xylosidase production by penicillium sclerotiorum and its characterization are reported. optimal production was obtained in medium supplemented with oat spelts xylan, ph 5.0, at 30 degrees c, under stationary condition for six days. the optimum activity temperature was 60 degrees c and unusual optimum ph 2.5. the enzyme was stable at 50 and 55 degrees c, with half-life of 240 and 232min, ... | 2009 | 19818316 |
| purification and characterization of two extracellular xylanases from penicillium sclerotiorum: a novel acidophilic xylanase. | two xylanases from the crude culture filtrate of penicillium sclerotiorum were purified to homogeneity by a rapid and efficient procedure, using ion-exchange and molecular exclusion chromatography. molecular masses estimated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis were 23.9 and 33.1 kda for xylanase i and ii, respectively. the native enzymes' molecular masses of 23.8 and 30.8 kda were estimated for xylanase i and ii, respectively, by molecular exclusion chromatography. both ... | 2010 | 19680819 |
| synthesis and antifungal activity of novel sclerotiorin analogues. | sclerotiorin 1, first isolated from penicillium sclerotiorum, has weak antifungal activity and belongs to the azaphilone-type family of natural products. several series of sclerotiorin analogues were designed and synthesized with the aim of discovering novel fungicides with improved activity. the syntheses involved two key steps, cycloisomerization and then oxidation, and used a simple and efficient sonogashira cross-coupling reaction to construct the required functionalized precursor. with scle ... | 2012 | 22439963 |
| design, synthesis and fungicidal activity of novel sclerotiorin derivatives. | sclerotiorin, a chlorine-containing azaphilone-type natural product, was first isolated from penicillium sclerotiorum and has been reported to exhibit weak fungicidal activity. optimization of the substituents at the 3- and 5-positions of the sclerotiorin framework was investigated with the aim of discovering novel fungicides with improved activity. the design of sclerotiorin analogues involved replacing the diene side chain with a phenyl group or an aromatic- or heteroaromatic-containing alipha ... | 2012 | 22834771 |
| high-level production of calcium malate from glucose by penicillium sclerotiorum k302. | in this study, after screening of 9 fungal strains for their ability to produce calcium malate, it was found that penicillium sclerotiorum k302 among them could produce high-level of calcium malate. under the optimal conditions, the titer of calcium malate in the supernatant was 88.6 g/l at flask level. during 10-l fermentation, the titer of 92.0 g/l, the yield of 0.88 g/g of glucose and the productivity of 1.23 g/l/h were reached within 72 h of the fermentation, demonstrating that the titer, yi ... | 2013 | 23831380 |
| (+)-cyclopenol, a new naturally occurring 7-membered 2,5-dioxopiperazine alkaloid from the fungus penicillium sclerotiorum endogenous with the chinese mangrove bruguiera gymnorrhiza. | one new naturally occurring 7-membered 2,5-dioxopiperazine alkaloid named (+)-cyclopenol (1), along with nine known compounds including viridicatol (2), 3-(dimethylaminomethyl)-1-(1,1-dimethyl-2-propenyl)indole (3), anacine (4), aurantiomide c (5), viridicatin (6), 3-o-methylviridicatin (7), verrucosidin (8), ergosterol (9), and ergosterol peroxide (10), was isolated from the etoac extract of fungus penicillium sclerotiorum, an endophytic fungal strain isolated from chinese mangrove bruguiera gy ... | 2014 | 24773150 |
| genome sequencing and analysis of the filamentous fungus penicillium sclerotiorum 113, isolated after hurricane sandy. | penicillium sclerotiorum is a distinctive species within the genus penicillium that usually produces vivid orange to red colonies, sometimes with colorful sclerotia. here, we report the first draft genome sequence of p. sclerotiorum strain 113, isolated in 2013 in the aftermath of hurricane sandy from a flooded home in new jersey. | 2016 | 27881534 |