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critical evaluation of oxfendazole as a swine anthelmintic.sixty feeder pigs with mixed naturally acquired nematode infections were medicated with oxfendazole, a new benzimidazolecarbamate compound, at dose levels of 0, 3, 9, and 18 mg/kg of body weight. the dosage of 3.0 mg/kg administered once in the feed proved as efficacious as larger dosages and the same dosage administered 2 or 3 times in the removal of adult ascaris suum, oesophagostomum dentatum, and metastrongylus pudendotectus. trichuris suis adults were less susceptible. anthelmintic efficacy ...1977851278
an evaluation of ethyl-6-ethoxybenzothiazole-2-carbamate (sch 18099) for anthelmintic activity in domestic animals.ethyl-6-ethoxybenzothiazole-2-carbamate (sch 18099) was evaluated for efficacy against natural helminth infections in ponies, pigs, lambs and chickens. sixteen critical trials were conducted in ponies at dosages of 15 to 150 mg/kg. at 15 mg/kg, efficacy against adult and larval oxyuris equi was 100% and 91% and against small strongyles it was 98%. efficacy levels were 95% against strongylus vulgaris and s. edentatus at the 20 mg/kg dosage. in two trials at 100 mg/kg efficacy against parascaris e ...1977864223
synergism between trichuris suis and the microbial flora of the large intestine causing dysentery in pigs.the role of the microbial flora of the large intestine in experimental trichuris suis infection was studied by comparing the clinical syndrome in conventionally reared (cr) pigs, specific pathogen-free pigs, and gnotobiotic pigs. thedisease in cr pigs was characterized by a severe mucohemorrhagic enteritis; in contrast, a mild catarrhal enteritis was observed in specific pathogen-free and gnotobiotic pigs. spirochaetes and vibrio-like organisms were observed only in cr pigs and increased during ...19751167536
influence of an experimental infection of trichuris suis on performance of pigs. 1979541282
dose titration of oxfendazole against common nematodes of swine.oxfendazole, a benzimidazole carbamate, was administered as a 0.5% feed additive to 88 pigs naturally infected with two to four nematode species. dose rates of 1.5 mg/kg of body weight, 3.0 mg/kg, 3.75 mg/kg, 4.5 mg/kg, 6.75 mg/kg, or 9.0 mg/kg were 100% efficacious against oesophagostomum dentatum and 99.2% to 100% effective against ascaris suum. dose rates of 4.5 mg/kg, 6.75 mg/kg, and 9.0 mg/kg were 92.7%, 98.9%, and 99.5% effective, respectively, against mixed populations of metastrongylus a ...1979464370
trichuris suis and t. muris: elemental analysis of intestinal inclusions. 1977191275
effect of pyrantel tartrate and carbadox on acquisition of the swine kidneyworm (stephanurus dentatus) and other parasites by pigs on contaminated lots.a combination of pyrantel tartrate (106 mg/kg of body weight) and carbadox (55 mg/kg of body weight) in ground feed was fed to 20 weaned pigs (av wt, 14.4 kg) for 42 days. another group of 20 pigs included nontreated controls. the pigs were farrowed and suckled in a slat-floored farrowing house and had minimal exposure to the small intestinal threadworm (stronglyoides ransomi) until they were placed on severely contaminated dirt lots at the start of the experiment. five pigs from each of the two ...1979160763
a comparative study of the histopathology of the large intestine of conventionally reared, specific pathogen free and gnotobiotic pigs infected with trichuris suis. 1976131812
structure and chemistry of the egg-shell of a nematode (trichuris suis). 1978725910
a survey of gastrointestinal parasites in pigs of the plateau and rivers states, nigeria.faecal samples were collected from a total of 1,000 pigs from the port harcourt and jos areas of the rivers and plateau states, respectively, between january 1987 and march 1988. in the jos area the parasite incidence was: ascaris suum 53.1%, trichuris suis 8.5%, hyostrongylus rubidus 13.1%, metastrongylus salmi 3.7%, strongyloides ransomi 87.7%, oesophagostomum dentatum 35.1% and eimeria spp. 2.4% while in port harcourt the incidence rate was ascaris suum 10.4%, trichuris suis 47.2%, oesophagos ...19902092354
field observations on the longevity of trichuris suis ova. 19873629887
trichinella spiralis: light microscope monoclonal antibody localization and immunochemical characterization of phosphorylcholine and other antigens in the muscle larva.a panel of monoclonal antibodies was used to examine the structure of the muscle larva of trichinella spiralis under the light microscope. immunofluorescence and, in some cases, immunoperoxidase staining were used. all four antibodies reacted with the cuticle of the organism, although differences in the staining pattern were observed for some of these. interestingly, all the antibodies also reacted with the stichosome. one of the antibodies (ts2ab) is specific for the hapten, phosphorylcholine. ...19911889472
[dissemination and survival of endoparasite embryos in the environment].pig farms with the annual capacity from five to 20 thousand head represent one of the crucial fields of agriculture influencing the environment in the csfr. daily production of large amounts of liquid excrements (150-300 m3), as a result of high concentrations of animals, poses not only technical but also sanitary problems closely related to the animal and man's health. in a long-term (267 days) field study the authors followed the development and survival of eggs of the model helminth ascaris s ...19911841477
erythrocyte losses from pigs with experimental trichuris suis infections measured with a whole-body counter. 19744218246
a morphological and histochemical study of trichuris suis (schrank, 1788) with special reference to the host-parasite relationship. 19704323589
transmission of intestinal helminths in danish sow herds.faecal samples from sows and their litters, all untreated with anthelmintics, were examined in eight sow herds, ranging from very intensive to very traditional management. four helminth genera were recorded, namely oesophagostomum sp., ascaris suum, trichuris suis and strongyloides ransomi. the herds with the most intensive management were only infected with a. suum, while the more traditionally managed herds were infected with three or four species. in one herd, the sows showed a small relative ...19911832796
histochemical and fine structure observations of the intestinal epithelium of trichuris suis (nematoda: trichuroidea). 19734358756
changes in the concentrations of serum urea nitrogen, albumin, globulin, sodium and inorganic phosphorus in weaner pigs infected with trichuris suis. 19744457568
[helminth infections in wild boars kept in enclosures in southern germany: severity of infections and fecal intensity].to determine the intensity of helminth infection and egg output with regard to age and sex of wild boar, stomachs and intestines of 124, lungs of 62, and livers of 39 animals from 5 enclosures in southern germany were examined. the evaluation of the intensity of infection showed 579.4 worms per animal for hyostrongylus rubidus, 510.4 for globocephalus longemucronatus, 476.9 for oesophagostomum dentatum, 476.9 for o. quadrispinulatum, 254.2 for metastrongylus pudendotectus, 176.9 for m. salmi, 14 ...19911796467
infectivity of embryonated trichuris suis eggs passed through the digestive tracts of post-weanling pigs. 19734736433
trichinella spiralis: antigenic epitopes from the stichocytes detected in the hypertrophic nuclei and cytoplasm of the parasitized muscle fibre (nurse cell) of the host.monoclonal antibodies raised against antigens present in the excretions/secretions (e/s) of larval trichinella spiralis, polyclonal antibodies raised against e/s and antisera from rabbits and pigs infected with t. spiralis were used in conjunction with immunocytochemical techniques to detect antigens in sections of muscle from mice that had been infected with t. spiralis for 15 or 30 days. the antibodies recognized epitopes in the stichocytes, on the surface of the cuticle, in the lumen of the o ...19911710049
efficacy of an in-feed preparation of ivermectin against endoparasites and scabies mites in swine.in 2 trials, the efficacy of an in-feed preparation of ivermectin was evaluated in 40 pigs naturally infected with endoparasites and sarcoptes scabiei var suis. treated pigs (n = 10 in each trial) were fed a ration containing 2 ppm ivermectin for 7 days, followed by consumption of a nonmedicated ration for the remainder of the trial. control pigs (n = 10 in each trial) were fed a complete, nonmedicated ration for the duration of the trial. pigs in trial a were monitored for 14 days after treatme ...19921586019
electron microscope observations of the body wall of trichuris suis, schrank, 1788 (nematoda: trichuroidea). i. the cuticle and bacillary band. 19694912261
specificity of affinity-purified trichinella spiralis antigens.an affinity-purified fraction (apf) was obtained by passing crude somatic antigens of trichinella spiralis muscle larvae through an affi-gel 10 column coupled with anti-trichuris suis igg. the fraction contained seven antigens with molecular weights ranging from 28 to 55 kda. when tested with antiserum against other common nematodes of pigs from china, the apf was found to be markedly more specific than s3 antigens (prepared by a combination of cell fractionation and differential centrifugation ...19921373256
evaluation of dichlorvos (v3 formulation) against larval and adult trichuris suis and observations on experimental infection in growing pigs. 19715103372
the relationship between trichuris trichiura (linnaeus 1758) of man and trichuris suis (schrank 1788) of the pig.studies were made on the relationship between trichuris suis of the pig and t trichiura of man. comparative morphological and developmental studies revealed differences in sizes of the eggs and infective first stage larvae, in the rate of development to the infective larval stage and in development within young pigs following experimental infection. successful cross infections of man with t suis ova and of pigs with t trichiura ova were achieved for the first time. t suis eggs recovered from one ...19761257627
[the destruction of parasitic resistant stages in sludge by irradiation with low accelerating voltage electrons (author's transl)].the destroying effect of ionizing radiation on parasitic resistant stages in sludge has been tested. suitable for that process is an electron beam accelerator which will be provided with energy from the electric power supply network which can be switched on and off according to the requirements. such modern utilities have an enormous beam capacity and a high operating safety. the process is working according to the continuous flow principle and at room temperature. in a series of 13 experiments ...19751189798
experimental and field studies with thiophanate in pigs.thiophanate, administered at a dosage of 50 mg per kg to artifically infected pigs, removed 96 to 99 per cent of adult oesophagostomum spp, hyostrongylus rubidus and trichuris suis. activity was also high against larval stages of these nematodes, except for 26-day-old t suis. thiophanate also showed ovicidal and larvicidal activity against h rubidus and oesophagostomum spp. at 50 mg per kg thiophanate administered alone was inactive against ascaris suum and metastrongylus apri, the former specie ...1976969196
pathophysiology of swine trichuriasis.infection of pigs by the whipworm (trichuris suis) resulted in profuse diarrhea on postinfection days 17 to 21. anorexia, retardation of growth, dehydration, and emaciation were observed in infected pigs. scanning electron micrography showed nematodes embedded in the mucosa of the cecum and colon, with resultant disruption of the mucosa. infected pigs had decreased values of albumin, amylase, calcium and creatine phosphokinase, but increased values of alpha-, beta-, and gamma- globulins, total i ...1977883715
levamisole: efficacy against trichuris suis. 1977835213
the trichurid egg-shell: evidence in support of the bouligand hypothesis of helicoidal architecture.electron microscopy of thin sections and freeze etch replicas of the eggs of the nematodes trichuris suis and t. muris is used to provide evidence in support of the bouligand hypothesis of helicoidal architecture. the evidence presented is as follows: 1. the specific objections to the bouligand model raised by dennell (1974) and dalingwater (1975b) are answered by reference to a pyramid of helicoidal tissue in which the corners are blunt. 2. sections cut normal to the plane of the laminae do not ...1978746539
comparative efficacy of fenbendazole, dichlorvos, and levamisole hci against gastrointestinal nematodes of pigs.forty-two weanling pigs raised under similar management conditions were used to compare the effectiveness of fenbendazole, dichlorvos, and levamisole hcl against oesophagostomum dentatum, o. quadrispinulatum, ascaris suum, trichuris suis, hyostrongylus rubidus, and strongyloides ransomi. all three drugs were given in the feed. eleven pigs served as unmedicated controls; 11 pigs received fenbendazole (3 mg/kg) on days 1, 2, and 3; 10 pigs received dichlorvos (17 mg/kg) on day 3; and 10 pigs recei ...1978739296
survival rates of parasite eggs in sludge during aerobic and anaerobic digestion.the effects of mesothermic anaerobic or aerobic sludge digestion on survival of eggs from the roundworms ascaris suum, toxocara canis, trichuris vulpis, and trichuris suis and from the rat tapeworm hymenolepis diminuta were studied. destruction of eggs throughout a 15-day treatment period, as well as their viabilities after reisolation, was analyzed. the laboratory model digesters used in this study were maintained at a 15-day retention schedule, partially simulating a continuously operating sys ...19826891199
losses to internal parasites in swine production.experimental infections of pigs with strongyloides ransomi, stephanurus dentatus, ascaris suum, oesophagostomum spp. or trichuris suis at increasing levels generally decrease daily gain and increase feed to gain ratio linearly. at lower, subclinical levels of infection, the feed to gain ratio typically is increased 3% to 6% by an infection. based on low-level experimental infections with a. suum, the economic loss to producers in the u.s. from increased feed to gain ratio is estimated at $155 mi ...19882969380
[parasites in the gdr.1. studies on helminths occurrence in european wild pigs (sus scrofa)].in two different hunting-grounds in the north-eastern part of the gdr from november 1972 to march 1974 the authors tested a series of 102 killed wild boars, aged mostly from 7 month to 3 years by means of helminthological dissection and by coprological methods for helminthic stages. from more than 30 well known species of helminths the following 10 species were found: cysticercus tenuicollis, echinococcus hydatidosus, ascaris suum, ascarops strongylina, physocephalus sexalatus, globocephalus uro ...1978646175
the development and survival of trichuris suis ova on pasture plots in the south of england.pasture plots in the south of england were contaminated each month throughout 1975 with pig faeces containing trichuris suis ova. at regular intervals thereafter, soil samples were taken, the t suis ova extracted and their state of development noted. depending on the time of year that the plots were contaminated, ova required between 62 and 90 weeks to complete their development to the infective stage. little or no development occurred during winter. once the infective stage was reached, the ova ...1979572984
parasites of domestic and wild animals in south africa. viii. helminths in pigs kept under semi-intensive conditions.the seasonal incidence of nematode infestations in pigs raised under semi-intensive conditions was determined by the monthly slaughter of 2--4 tracer pigs exposed to infestation in an earthernfloored pen for periods of 1 or 2 months. although worm burdens were generally small, ascarops strongylina appeared to be more prevalent from november to march than during the other months of the year. once ascaris suum became established in the pen nearly all the pigs became infested. the number of worms n ...1978568231
parasites of domestic and wild animals in south africa. vii. helminths in pigs slaughtered at the pretoria municipal abattoir.a total of 52 pigs slaughtered at the pretoria municipal abattoir over a period of 1 year was examined for parastitic helminths. twenty-six of these pigs were marketed by farmers and 26 by speculators. of the pigs marketed by farmers 73,1% were found to be infested:--30,8% with ascaris suum, 65,4% with ascarops strongylina, 3,8% with metastrongylus apri, 26,9% with oesophagostomum spp., 15,4% with trichostrongylus colubriformis and 15,4% with trichuris suis. all the pigs marketed by speculators ...1978568230
[helminth infections in wild boars in enclosures in southern germany: species spectrum and infection frequency].to determine the helminth fauna of wild boars, stomachs and intestines of 124, lungs of 62, and livers of 39 animals from 5 enclosures in southern germany were examined. the evaluation of the species composition revealed at least 13 species: metastrongylus apri, m. salmi, m. pudendotectus, physocephalus sexalatus, hyostrongylus rubidus, globocephalus longemucronatus, ascaris suum, trichuris suis, oesophagostomum dentatum, o. quadrispinulatum, fasciola hepatica, c. tenuicollis and capillaria. the ...19902264058
molecular cloning and expression of an immunodominant 53-kda excretory-secretory antigen from trichinella spiralis muscle larvae.a trichinella spiralis cdna expression library was constructed in lambda gt11 from muscle larvae mrna and immunologically screened to identify genes encoding previously described immunodiagnostic excretory-secretory (es) antigens. screening the library with t. spiralis infection serum from swine or rabbit antiserum to t. spiralis es antigen identified one clone, designated tsa-12, that contains a cdna transcript 539 bp in length and codes for an apparent 123-kda beta-galactosidase fusion protein ...19902270099
an abattoir survey of the prevalence of gastro-intestinal helminths and stephanurus dentatus in pigs in belize.in an abattoir survey in belize 137 pigs were examined for gastro-intestinal helminths and stephanurus dentatus. hyostrongylus rubidus, physocephalus sexalatus, globocephalus species and trichostrongylus colubriformis were recorded for the first time. ascarops strongylina, ascaris suum, macracanthorynchus hirudinaceus, strongyloides ransomi, trichuris suis, oesophagostomum species and s. dentatus were also found. oesophagostomum species (45%) and s. dentatus (42%) were the most prevalent. the pr ...19892529683
influence of helminth parasite exposure and strategic application of anthelmintics on the development of immunity and growth of swine.infection of pigs with the intestinal roundworm parasite ascaris suum and strategic application of anthelmintic drugs during the growing phase of development were observed for specific effects on 1) development of immunity in feeder pigs and 2) growth rate during the finishing phase. management treatments included maintenance in a parasite-free concrete environment, maintenance in a concrete environment and inoculation with 1,000 infective a. suum eggs every other day over a 52-d period, and mai ...19892768122
trichuris suis: a zinc metalloprotease from culture fluids of adult parasites.a zinc metalloendoprotease has been isolated from in vitro culture fluids of trichuris suis adults. the protease was purified from total culture fluids by passage through a cation exchange high-pressure liquid chromatography column. the 45-kda protease has a ph optimum of 7.0 and an isoelectric point of 8.0 and was localized to the stichosome of the parasites using immunohistochemistry techniques.19938375486
prevalence of helminth infections in swine in denmark.during 1982-1984 the occurrence of helminths in 66 sow herds was determined by examining faecal samples from swine of different age groups. ascaris suum was found in 88% of the herds, while oesophagostomum spp. and trichuris suis were found in 58 and 23% of the herds, respectively. strongyloides ransomi and hyostrongylus rubidus was not identified in any of the herds. the occurrence of both a. suum and oesophagostomum spp. was strongly related to the age of the animals. a. suum was most frequent ...19892815533
efficacy of dichlorvos, fenbendazole, and ivermectin in swine with induced intestinal nematode infections.anthelmintic efficacies of dichlorvos, fenbendazole, and ivermectin were compared in specific-pathogen-free crossbred weanling pigs inoculated with ascaris suum, trichuris suis, and oesophagostomum dentatum. on postinoculation day (pid) 50, 24 pigs in each treatment group were treated orally with 43 mg of dichlorvos/kg of body weight, 3 x 3 mg of fenbendazole/kg, or 300 micrograms of ivermectin/kg, sc. twenty-four pigs were not treated. on posttreatment day 7 (pid 57), 12 pigs from each treatmen ...19873631712
parasite transmission in confined hogs.examinations of fecal specimens from swine of all ages maintained in a totally enclosed confinement facility in south georgia were conducted in a 5-year survey (1977-1981) to determine the prevalence, intensity, and transmission patterns of intestinal nematode and protozoan parasites. weaned pigs in the nursery had no detectable parasitic infections except sporadic isospora suis in newly weaned pigs. growing-finishing hogs had a low prevalence of ascaris suum, oesophagostomum spp. and balantidiu ...19863705423
electron microscope observations of the body wall of trichuris suis, schrank, 1788 (nematoda: trichuroidea). ii. the hypodermis and somatic musculature. 19724339869
spirochaetal invasion of the colonic mucosa in a syndrome resembling swine dysentery following experimental trichuris suis infection in weaned pigs. 19724539730
studies on the biology of the life-cycle of trichuris suis schrank, 1788. 19734761766
morphological descriptions of the egg and larval stages of trichuris suis schrank, 1788. 19734761767
the pathogenesis of necrotic proliferative colitis in swine is linked to whipworm induced suppression of mucosal immunity to resident bacteria.mucohemorrhagic enteritis syndrome in swine has a complex etiology with largely unknown pathogenesis. we have observed that inoculation of pigs with swine whipworm, trichuris suis, initiates an interaction with resident bacterial flora to induce mucohemorrhagic enteritis. the role of bacteria in this mixed infection was demonstrated using 4 treatment groups. one group of pigs was inoculated with 2500 embryonated t. suis eggs alone, while a second group received t. suis eggs along with broad spec ...19969157675
experimental infection of man with pig whipworm. 19715102492
validation of the specificity of the modified agglutination test for toxoplasmosis in pigs.serum samples from toxoplasma gondii-negative pigs infected with protozoa, helminths and viruses, and from fetal pigs were examined for cross reacting antibodies to t. gondii by the use of the modified agglutination test (mat). nonspecific reactions with t. gondii antigen were not found in 1:10 dilutions of sera from eight pigs experimentally infected with sarcocystis miescheriana, 11 pigs infected with ascaris suum, three pigs infected with trichuris suis, ten pigs infected with trichinella spi ...19979299699
immunodiagnosis of giardiasis by elisa and studies on cross-reactivity between the anti-giardia lamblia antibodies and some heterologous parasitic antigens and fractions.specific antibodies against giardia lamblia in 92 sera from asymptomatic carriers were investigated by elisa. using cyst antigen, antibodies were detected in 91 of the sera, by means of alkaline phosphatase-labelled antispecies immunoglobulin. the e/405nm values of the positive sera ranged between 0.350 and 1.700, whereas in the 78 control sera they were 0.270 +/- 0.220. cross-reactivity between the anti-g. lamblia antibodies and 18 heterologous parasitic antigens and fractions was also studied. ...19846486935
anthelmintic activity of ivermectin in pigs naturally infected with ascaris and trichuris.the anthelmintic efficacy of ivermectin administered by subcutaneous (sc) injection or orally via the drinking water was investigated in feeder pigs naturally infected with ascaris suum and trichuris suis. group 1 pigs (n = 5) were given drinking water as a placebo, group 2 pigs (n = 5) were given ivermectin by sc injection (300 micrograms/kg of body weight), and group 3 pigs (n = 5) were given ivermectin in water also at a dosage rate of 300 micrograms/kg of body weight. at necropsy 11 days lat ...19836688706
evaluation of fenbendazole as an extended anthelmintic treatment regimen for swine.fenbendazole was given in the feed to swine at a cumulative dosage of 9 mg/kg of body weight over a period of 3, 6, and 12 days to compare efficacy. four treatment groups of ten 2- to 3-month-old pigs each, with a mean of 15 kg of body weight per group, received 3 mg of fenbendazole/kg/day for 3 days, 1.5 mg/kg/day for 6 days, 0.75 mg/kg/day for 12 days, and no medication. medicated feed was scheduled so that all treated pigs reached the last day of treatment on the same day, thus making the tim ...19846746372
production specific antigens from trichinella spiralis using a continuous elution method and isoelectric focusing.immunodominant antigens of 45-53 kda (one band per fraction) were obtained from excretory/secretory (e/s) and somatic products of infective-larvae of trichinella spiralis using a continuous-elution method. they were further resolved by isoelectric focusing into different isoforms (45 kda: pi4.47, 5.09, 5.47 and 5.86; 47 kda: pi4.72 and 4.97; 53 kda: pi4.86, 5.11, 5.44 and 5.78). in immunoblotting, the isoforms of pi 5.09, 5.86, 4.97, 5.44 and 5.78 did not cross-react with antisera against trichu ...19979656358
flubendazole: dose range and efficacy studies against common internal parasites of swine.the anthelmintic spectrum of activity and efficacy of flubendazole, using pigs naturally infected with helminth parasites, were determined in 4 experiments, using 157 pigs. flubendazole (1.5 mg/kg of body weight) mixed in feed or top-dressed on feed for 5 consecutive days was highly effective as an anthelmintic. this dosage level indicated 100% efficacy against mature ascaris suum, oesophagostomum dentatum, trichuris suis, and metastrongylus apri. there was 88% efficacy against strongyloides ran ...19836881670
determination of the specific gravity of certain helminth eggs using sucrose density gradient centrifugation.the specific gravities of ten species of helminth eggs were determined using sucrose density gradient centrifugation. fecal or egg concentrate was layered over a 3 to 54% sucrose density gradient. the gradient was then centrifuged at 800 g for 20 min, allowing 5 min for acceleration and 5 for deceleration. bands formed were identified and measured. refractive index was measured at the middle of narrow bands, or at the level at which the concentration of eggs was highest, in the case of wide band ...19826890102
activity of doramectin against nematode and arthropod parasites of swine.the efficacy of doramectin, a novel avermectin, was assessed against both naturally-acquired and experimentally-induced infections of gastrointestinal roundworms, lungworms, kidneyworms, lice and mites in studies conducted across north america and europe. twenty-two studies evaluated efficacy against fourth larval and adult stages of the following nematode species: hyostrongylus rubidus, ascaris suum, strongyloides ransomi, oesophagostomum dentatum, oesophagostomum quadrispinulatum, trichuris su ...19968988559
doramectin efficacy against gastrointestinal nematodes in pigs.four controlled trials with growing pigs were performed to determine efficacy of doramectin against natural and induced populations of nematodes. in trial 1 (t1), 20 pigs with natural infections were assigned to one of two like groups on the basis of weight, sex and worm egg counts. in trial 2 (t2), 20 pigs with negative worm egg counts were assigned to one of two groups on the basis of weight and sex. each pig was subsequently given (per os) 3000 trichuris suis embryonated eggs; 2000 ascaris su ...19968988561
trichuris suis: thiol protease activity from adult worms.trichuris suis, the whipworm of swine, causes anemia, weight loss, anorexia, mucohemorrhagic diarrhea, and death in heavy infections. a zinc metalloprotease has been suggested to play a role in the severe enteric pathology associated with infection and the infiltration of opportunistic bacteria into deeper tissues in the swine colon. in this study, a thiol protease from gut extracts of adult t. suis and from excretory/secretory components (e/s) of adult worms was characterized using fluorogenic ...19979024202
a trichuris specific diagnostic antigen from culture fluids of trichuris suis adult worms.trichuris suis is a nematode parasite of swine which can cause serious pathology in infected pigs, such as anorexia, diarrhea, anemia, and death in heavy infections, especially in young animals. infection with trichuris suis is difficult to diagnose because much of the pathology occurs when only larval stages are present, and because of sporadic egg production by adult female worms. we have isolated a 20 kda excretory/secretory (e/s) glycoprotein from culture fluids of adult worms by column chro ...19979066055
efficacy of doramectin against intestinal nematodes and sarcoptic manage mites in naturally infected swine.endectocidal efficacy of doramectin administered intramuscularly at a dosage of 300 micrograms/kg was evaluated in 464 pigs naturally infected with intestinal nematodes or mange mites on 14 commercial farms in japan. by doramectin treatment, fecal egg counts were reduced > 99% for ascaris suum, strongyloides ransomi, oesophagostomum dentatum, and trichuris suis; worm counts of t. suis and mite counts of sarcoptes scabiei reduced 90.1% on day 21 and 99.5% on day 28 following treatment, respective ...19979070986
transmission dynamics of helminth parasites of pigs on continuous pasture: ascaris suum and trichuris suis.in denmark, alternative outdoor production systems for pigs are becoming more frequent, and information on the transmission of ascaris suum and trichuris suis under continuously grazed pasture conditions is needed. a group of pigs was turned out on a pasture in may 1993 (year 1 of the study), inoculated with 200 eggs of a. suum and 1000 eggs of t. suis, and followed parasitologically. a non-experimentally infected group of pigs was similarly turned out on the same pasture the following year (yea ...19979193950
schistosoma japonicum and trichuris suis infections in pigs fed diets with high and low protein.the aim of the study was to measure the impact of schistosoma japonicum and trichuris suis infections in young growing pigs fed low- or high-protein diets. thirty-two pigs. 6-10 weeks old, were randomly allocated to 2 groups receiving either a high- or a low-protein diet. after 11 weeks half of the pigs from each group were infected with 1500 s. japonicum cercariae and 4000 t. suis eggs. the weight of the pigs was measured throughout the study, and blood and faecal samples were collected every s ...19979300463
trichuris suis infection in young pigs. 19705198017
helminthosis in local and cross-bred pigs in the morogoro region of tanzania.we investigated the prevalence, burden and types of gastro-intestinal helminths in 424 local and cross-bred pigs kept under different management systems in two climatic zones in the morogoro region of tanzania. coprological examination revealed that 53% of the pigs excreted helminth eggs in their faeces. the median eggs per gram of faeces (epg) was 500 (range 100-22,000). local breeds in the mgeta location with tropical highland climate showed significantly higher prevalence (p < 0.001) and medi ...19979361319
prevalence and distribution of pig helminths in the dongting lake region (hunan province) of the people's republic of china.the prevalence of helminths in pigs was investigated in five rural communities situated on the embankment of dongting lake in zhiyang county, hunan province, people's republic of china, in an area known to be endemic for schistosoma japonicum. the helminth prevalences identified on the basis of faecal egg count analysis were: oesophagostomum spp. (86.7%), ascaris suum (36.7%), metastrongylus spp. (25.8%), strongyloides spp. (25.8%), trichuris suis (15.8%), globocephalus spp. (6.7%), gnathostoma ...200010831052
intestinal parasites in swine in the nordic countries: prevalence and geographical distribution.in denmark (dk), finland (fin), iceland (i), norway (n), and sweden (s), 516 swine herds were randomly selected in 1986-1988. individual faecal analyses (mean: 27.9 per herd) from eight age categories of swine showed that ascaris suum, oesophagostomum spp., isospora suis, and eimeria spp. were common, while trichuris suis and strongyloides ransomi-like eggs occurred sporadically. large fatteners and gilts were most frequently infected with a. suum with maximum prevalences of 25-35% in dk, n and ...19989650867
monoclonal antibody-purified antigen for the immunodiagnosis of trichinosis.monoclonal antibodies generated from spleen cells of balb/cj mice infected with trichinella spiralis reacted with antigenic determinants present in some other common swine parasites, especially trichuris suis. an antigenic determinant unique to t spiralis was recognized by one immunoglobulin m monoclonal antibody (7c2c5); this determinant was found on larval t spiralis proteins with molecular weights of 53,000, 49,000, and 45,000. these proteins were components of in vitro-derived worm excretory ...19846703457
morphologic, biometric, and isoenzyme characterization of trichuris suis.trichuris suis isolates were collected from the cecum of sus scrofa domestica (pig) and s. s. scrofa (wild boar). morphology and biometry studies were carried out. morphology studies showed the existence of typical caudal papillae in males of t. suis from wild boars, but no other difference was observed in the biometric parameters (total length, esophageal length, posterior-portion body length, and spicular length) of t. suis isolated from either host. individual extracts were subjected to malat ...19989660144
false-positive trichuris suis egg counts in pigs in relation to coprophagia.sixteen non-infected control pigs housed together with 16 pigs infected with trichuris suis, excreted t. suis eggs in their faeces (range 20-4, 960 eggs per gram faeces (epg)). when the control pigs were moved to clean pens, their egg counts dropped to zero epg within five days. a significant correlation was found between t. suis egg counts of infected and control pigs penned together (r = 0.89, p < 0.001). these results suggest that false-positive faecal egg counts may be the result of copropha ...19989754304
efficacy of ivermectin against five genera of swine nematodes and the hog louse, haematopinus suis.twenty pigs sequentially infected with oesophagostomum spp, metastrongylus spp, and trichuris suis, and maintained on lots contaminated with ascaris suum and strongyloides ransomi, were assigned to 1 of 4 groups on the basis of weight, sex, and litter. each group of pigs was given ivermectin subcutaneously at the rate of 0, 20, 100, or 500 microgram/kg of body weight. lice on pigs were counted before treatment, on posttreatment day 1, and just before necropsy. pigs were necropsied on posttreatme ...19816895286
treatment of trichuris suis infections in pigs with flubendazole.a severe outbreak of trichuris suis infection in piglets is described. fifteen per cent of the animals died and the morbidity, characterised by weight loss and diarrhoea, was over 50 per cent. the severity of symptoms observed in naturally infected pigs was related to the number of whipworms. a chemotherapeutic trial was worked out with flubendazole mixed in food for naturally infected and artificially infected piglets. flubendazole at 30 ppm for five consecutive days controlled the infection in ...19827101714
a survey of gastrointestinal parasitism in pigs.over a period of two years 180 pork pigs, 144 baconers and 144 sows from two slaughterhouses in northern england were examined for gastrointestinal parasites. sows showed the highest level and intensity of infection, 85 per cent harbouring the dominant parasites oesophagostomum dentatum and o quadrispinulatum; the highest worm burden recorded was 21,000. hyostrongylus rubidus was present in 28.5 per cent of sows but virtually absent from younger pigs. small numbers of ascaris suum and trichuris ...19807257108
efficacy of fenbendazole against five genera of swine parasites.thirty-three pigs were sequentially infected with oesophagostomum spp, metastrongylus spp, and trichuris suis while being maintained in lots contaminated with space ascaris suum, strongyloides ransomi, and other parasites. pigs were assigned to 1 of 3 groups on the basis of weight (6.8 to 25.9 kg), sex, and litter. pigs in the 1st group were used as nontreated controls; pigs in the 2nd and 3rd groups were given fenbendazole in the feed at doses of 3 and 5 mg/kg of body weight, respectively, on 3 ...19817271035
the influence of stocking rate on transmission of helminth parasites in pigs on permanent pasture during two consecutive summers.this study was made to elucidate the transmission of nematode infections in outdoor pigs at different stocking rates during two consecutive seasons. five pigs (group 1a) inoculated with low doses of oesophagostomum dentatum, ascaris suum, and trichuris suis and five helminth-naïve pigs (group 1b) were turned out together in june 1996 on each of four pastures at stocking rates of 100, 240 (two pastures) and 576m(2) per pig, respectively. the pigs were slaughtered in early october, and pasture inf ...200111470180
chickens and pigs as transport hosts for ascaris, trichuris and oesophagostomum eggs.ten chickens and 2 pigs were fed non-embryonated eggs of ascaris suum, trichuris suis and oesophagostomum dentatum. each chicken was fed approximately 15,000 eggs of each parasite species while approximately 300,000 eggs were given to each of the pigs. after passage in chickens 8.3% of o. dentatum eggs were recovered in faeces compared to 61.1% and 38.4%, 49.1% and 30.3%, 41.6% of a. suum and t. suis eggs, respectively. after passage in pigs the percentages were respectively. after embryonation ...200111578097
localization of phenol oxidase in female trichuris suis.a phenol oxidase (e.c. 1.10.3.1) preparation from adult female trichuris suis was assayed by both polarographic and spectrophotometric techniques. the t. suis enzyme oxidized most diphenols including 4-methylcatechol (4mc) and dihydroxyphenylalanine but did not oxidize tyrosine. the ph and temperature optima were 6.8 and 36 c, respectively. the km measured using 4mc as a substrate ranged from 0.12 to 0.4 mm. the highest phenol oxidase activity was isolated in fractions from the adult females tha ...19947799168
trichuris suis: detection of antibacterial activity in excretory-secretory products from adults.antibacterial activity was detected in excretory-secretory products (esp) of adult trichuris suis cultured in vitro in serum-free media. gram-negative bacteria (campylobacter jejuni, campylobacter coli, and escherichia coli) and gram-positive bacteria (staphylococcus aureus) were sensitive to esp. susceptibility was dependent on the concentration of esp but not on the inoculum size. preliminary assessment of the mode of action suggests a bacteriocidal mechanism. this antibacterial activity was h ...200111708831
[study of the efficacy of sewage treatment systems for fluid waste on pig farms in slovakia].bacteriological, helminthological and physico-chemical examinations were carried out to investigate the technological procedure in three water treatment plants treating slurry from large-capacity pig farms (kosická polianka, spisské vlachy, vel'ký dur). our investigations were focused on the testing of effectiveness of mechanical, chemical and biological treatment system most frequently used in slovakia. our investigations revealed that water-treatment plants, operating on pig farms, fulfil only ...19947817500
doramectin, a new avermectin highly efficacious against gastrointestinal nematodes and lungworms of cattle and pigs: two studies carried out under field conditions in germany.two field studies were carried out to confirm the efficacy of doramectin in cattle and pigs in europe. a total of 40 cattle harbouring naturally acquired infections of gastrointestinal nematodes, including ostertagia spp., oesophagostomum spp., cooperia spp., haemonchus spp., nematodirus spp. and trichuris spp., were allocated to a treated or a control group (20 animals/group), and 100 harbouring naturally acquired infections of gastrointestinal nematodes and lungworms, including oesophagostomum ...19938278344
the ecology of animal parasitic nematodes in endemic areas of jos, nigeria.a survey involving 3418 faecal samples collected from three areas of heavy human and animal activities in jos, nigeria showed that 2354 (68.9%) of the samples harboured various parasitic nematodes of man and animals. altogether, twelve species of parasitic nematodes were encountered. five of these, namely: ascaris lumbricoides, ancylostoma duodenale, necator americanus, trichuris trichiura and strongyloides stercoralis infect man while five others: trichostrongylus probolurus, t. colubriformis, ...19938334456
[the helminth fauna of wild boars of the west berlin forests].samples of muscles and internal organs obtained from 96 wild boars in the forests of west berlin between september 1989 and august 1990, were examined for helminths. nine nematode species, metastrongylus pudendotectus, m. salmi, m. confusus, m. apri, physocephalus sexalatus, ascarops strongylina, globocephalus urosubulatus, ascaris suum and trichuris suis belonging to five families could be found. larvae of toxocara spp. were isolated from most of the enzymatically digested samples of the gastro ...19938343108
the occurrence of phenol oxidase activity in female trichuris suis.the body of trichuris suis females maintained in vitro under a gas phase of 95% air 5% co2 develops a brown pigment that is apparent after 1 day and intensifies with time. development of the brown pigment is prevented by maintaining the parasites in an anaerobic gas phase (95% n2, 5% co2), but tanning commences when worms are returned to aerobic conditions. tanning was not observed in males. intact female t. suis take up oxygen at a considerably higher rate than males. supernatant fractions (10, ...19938459324
[intestinal geohelminthosis in man and domestic animals in the riverside sections of the valdivia river basin, chile].in march-october 1987 were analyzed 1295 coprological specimens in a sample of the human population who lives in riverside localities in the valdivia river basin, chile. a 23.6% of examined persons presented infection by one or more helminth species. the prevalence of infection by ascaris lumbricoides, trichuris trichiura and trichostrongylidae gen. sp. were 15.5, 12.7 and 0.2%, respectively. the prevalence of human ascariosis and trichuriosis were greater in pre-school and school children. the ...19958762668
identification, isolation, and characterization of a species-specific 30-kda antigen of oesophagostomum dentatum.in the search for a serology tool for the diagnosis of nonpatent as well as patent infections with oesophagostomum dentatum in pigs a water-soluble, unglycosilated antigen of about 30 kda specific for the third-stage larvae of the parasite was purified by ion-exchange chromatography. in western blots, the antigen was first detected by antibodies at day 7 postinfection. cross-reactivity with o. quadrispinulatum, ascaris suum, or trichuris suis was not detected. it is suggested that this protein i ...199910099013
seasonal variation in development and survival of ascaris suum and trichuris suis eggs on pastures.pig faeces were deposited on experimental plots in the spring, summer, autumn and winter to study development and survival of ascaris suum and trichuris suis eggs under outdoor conditions. faeces were placed either in short grass or 2 cm below the surface of bare soil, imitating pastures used by nose-ringed, grazing pigs or normally rooting pigs, respectively. the numbers and developmental stages of the eggs were recorded in faeces and soil for up to 50 weeks post-deposition. embryonation took p ...199910466129
health status of a recently discovered population of feral swine in kansas.twenty feral hogs (sus scrofa) from a newly discovered population on fort riley army base (kansas, usa) were shot and examined from november 1993 through february 1994 to assess the health of the population. the hogs were generally healthy, although serologic evidence indicated that some individuals had been exposed to parvovirus, enterovirus, and swine influenza. we found no indications of brucellosis, pseudorabies, or porcine respiratory and reproductive syndrome. lung worms (metastrongylus sp ...199910479106
efficacy of moxidectin 0.5% pour-on against swine nematodes.forty pigs with induced infections of ascaris suum, trichuris suis, metastrongylus spp., oesophagostomum dentatum and o. quadrispinulatum were assigned to five-dose groups of moxidectin 0.5% pour-on with eight pigs per dose group. the doses were: moxidectin, 0 (vehicle control), 0.75, 1.00, 1.25, and 1.50 mg/kg(-1) body weight. worm egg counts (epg) were made from fecal samples collected on day 2 pretreatment and on day 14 or 15 post-treatment. animals were ranked according to the descending ord ...199910628698
parasites in cross-bred pigs in the upper east region of ghana.a cross-sectional study was carried out in the upper east region (uer) of ghana in order to estimate the prevalence of parasitic infections in local cross-bred pigs. out of 60 villages with a human population of 200-1000 inhabitants, 10 villages were randomly selected for the study. the number of pigs varied from 50 to 200 pigs per village. in total 259 faecal samples from growers were collected and examined. ninety-one percent of the animals excreted parasite eggs. among these the prevalence of ...199910628701
experimental infections of swine with trichuris suis. 196014434579
trichuris suis: a secretory serine protease inhibitor.a trypsin inhibitor was identified in extracts of adult trichuris suis and culture fluids from 24-h in vitro cultivation of adult parasites. the inhibitor was isolated by acid precipitation, affinity chromatography (trypsin-agarose), and reverse phase hplc as a single polypeptide with a molecular weight estimated at 6.6 kda by laser desorption mass spectrometry. the purified inhibitor associated strongly with trypsin (equilibrium dissociation inhibitory constant (k(j)) of 3.07 nm) and chymotryps ...200010631074
efficacy of doramectin against naturally acquired nematode infection in iberian swine.studies were carried out to determine the therapeutic efficacy of doramectin, administered intramuscularly at a dose of 300 microg/kg live weight, against naturally acquired helminths of extensively farmed iberian pigs. the first study (slaughter study) evaluated, through necropsy of the study animals, the product's efficacy against gastrointestinal and pulmonary nematodes (ascaris suum, oesophagostomum dentatum and metastrongylus sp.) whilst the second, faecal egg count reduction study, (fecr s ...200010729654
[endoparasites in swine in different age groups and management systems].in different age groups endoparasites are of varying importance. sows are predominantly infected with gastrointestinal strongyles (mainly oesophagostomum spp.), ascaris suum and eimeriae, to a lesset extent with trichuris suis, hyostrongylus rubidus, strongyloides ransomi or isospora suis, while in suckling piglets i. suis and occasionally s. ransomi frequently occur. weaners and fatteners are infected with coccidia and gastrointestinal strongyles, later with a. suum. whipworms are also found oc ...200010816911
construction of internal cdna competitors for measuring il-10 and il-12 cytokine gene expression in swine.a competitive pcr assay (cpcr) was used to quantify swine cytokine responses to parasite infection. internal standards (deleted cdna competitor molecules [dcdna mimics]) were produced and tested for swine interleukin-12 (il-12), interleukin-10 (il-10) and hypoxanthine phosphoribosyltransferase (hprt) from pcr generated cdna cloned in plasmid vectors. deletion clones for the cdna competitor molecules (dcdna mimics) were generated for il-10, il-12 and hprt by pcr in a single step and verified by ( ...19989802577
trichuris suis: a secretory chymotrypsin/elastase inhibitor with potential as an immunomodulator.a serine protease inhibitor, termed tscei, was purified from adult-stage trichuris suis by acid precipitation, affinity chromatography (elastase-agarose), and reverse-phase hplc. the molecular weight of tscei was estimated at 6.437 kda by laser desorption mass spectrometry. tscei potently inhibited both chymotrypsin (k(i) = 33.4 pm) and pancreatic elastase (k(i) = 8.32 nm). neutrophil elastase, chymase (mouse mast cell protease-1, mmcp-1), and cathepsin g were also inhibited by tscei, whereas tr ...200010864516
nose-rings and transmission of helminth parasites in outdoor pigs.five growing pigs experimentally infected with low doses of oesophagostomum dentatum, ascaris suum, and trichuris suis were turned out with 5 helminth-naïve pigs on each of 3 pastures in june 1996 (group 1). on one pasture all pigs received nose-rings. after slaughter of group 1 in october, pasture infectivity was monitored using helminth-naïve, unringed tracer pigs. in 1997, helminth-naïve young pigs were turned out on the contaminated pastures in may (group 2) and again in august (group 3). ag ...200010965566
the prevalence of internal and external parasites in pigs of different ages and sexes in southeast district, botswana.botswana imports most pig-based products from neighbouring countries. pig farming is limited by, among other things, the negative effect of parasites and diseases on production. the object of this study was to determine the prevalence of ecto- and endoparasites in pigs of different ages and sexes in the southeast district of botswana. thirty-nine pigs were sampled for endoparasites and 19 for ectoparasites during a period of 2 1/2 months. of all the pigs sampled, 54,55% were infected with ascari ...200011131123
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