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studies on the anti-inflammatory activity of moschus moschiferus (musk) and its possible mode of action. 19734788506
[clinical effect and experimental study of xijian tongshuan pill].xijian tongshuan pill (xjts), consisted of siegesbeckia orientalis, moschus moschiferus, hirudo nipponica, prunus persicae, carthamus tinctoruis, ligusticum wallichi, panax notoginseng, angelica sinensis, borneolum, etc, were used in treating 70 patients with cerebral thrombosis. the marked effective rate was 82.9%, total effective rate was 96.7%. in control group a, dextranum and venoruton were used, in control group b cyclandelate capsule were used. the marked effective rate was 61.7% and 61.1 ...19948044010
[the taxonomy of the musk deer (artiodactyla, mammalia)].the results of multiyear studies (1976-1996) of musk deer taxonomy and the published data were generalized. two groups of subspecies were isolated on the basis of statistical analysis of 13 linear measurements and six indices in 388 skulls from different parts of the range. group "sibirica" includes four subspecies: siberian moschus moschiferus moschiferus f., verkhoyansk m. moschiferus articticus f., far-eastern m. moschiferus turowi zal., and sakhalin m. moschiferus sachalinensis f. group "him ...19979518057
[food specialization in ruminants: the role of endosymbiosis in its formation].peculiarities of endosymbiosis have been studied in four species of ruminant animals with different food specialization (cervus elaphus, moschus moschiferus, carpa sibirica, ans gasella subgutturosa) using the methods of macromorphology, light and electron microscopy, and histochemistry. the differences in morphology of bacteria from populations inhabiting rumen epithelium of the studied animals have been revealed. the specificity of connection of bacteria with cornified epithelium has been demo ...19892745856
x chromosome evolution in cetartiodactyla.the phenomenon of a remarkable conservation of the x chromosome in eutherian mammals has been first described by susumu ohno in 1964. a notable exception is the cetartiodactyl x chromosome, which varies widely in morphology and g-banding pattern between species. it is hypothesized that this sex chromosome has undergone multiple rearrangements that changed the centromere position and the order of syntenic segments over the last 80 million years of cetartiodactyla speciation. to investigate its ev ...201728858207
cross-species chromosome painting in cetartiodactyla: reconstructing the karyotype evolution in key phylogenetic lineages.recent molecular and morphological studies place artiodactyla and cetacea into the order cetartiodactyla. within the cetartiodactyla such families as bovidae, cervidae, and suidae are well studied by comparative chromosome painting, but many taxa that are crucial for understanding cetartiodactyl phylogeny remain poorly studied. here we present the genome-wide comparative maps of five cetartiodactyl species obtained by chromosome painting with human and dromedary paint probes from four taxa: ceta ...200919350402
musk deer (moschus spp.) face redistribution to higher elevations and latitudes under climate change in china.the population of wild musk deer (moschus spp.) has declined in recent decades and reached an endangered status in china. global climate change may drive the extinction rate of these species. to understand the implications of global warming on the future potential space utilization and migration direction of musk deer, both the maximum entropy model and barycenter migration analysis were utilized. five global climate models and four representative concentration pathway scenarios were considered ...202031784177
the noncervical lateral transverse foramina.the lateral vertebral foramen (lvf) is an osseous feature found in thoracic and lumbar vertebrae of some artiodactyls and perissodactyls. to learn more about the distribution and characteristics of the lvf, we examined museum specimens from the smithsonian mammal collection and teaching specimens from the cornell university college of veterinary medicine. we identified five anatomically different types of lvf and noted their occurrence in 60 species. the lvf varies from a deep lateral groove at ...201830350317
dna barcoding revises a misidentification on musk deer.as an endangered animal group in china, musk deer (genus moschus) have attracted the attention of deer biologists and wildlife conservationists. clarifying the taxonomic status and distribution of musk deer species is important to determine the conservation status for each species and establish appropriate conservation strategies. there remains some uncertainty about the species determination of the musk deer in the guandi forest district of shanxi province, china. the musk deer in shanxi would ...201524491100
whole-genome sequencing of wild siberian musk deer (moschus moschiferus) provides insights into its genetic features.siberian musk deer, one of the seven species, is distributed in coniferous forests of asia. worldwide, the population size of siberian musk deer is threatened by severe illegal poaching for commercially valuable musk and meat, habitat losses, and forest fire. at present, this species is categorized as vulnerable on the iucn red list. however, the genetic information of siberian musk deer is largely unexplored.202032005147
jageum-jung improves 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice and suppresses pro-inflammatory chemokine production by inhibiting tnf-α/ifn-γ-induced stat-1 and nfκb signaling in hacat cells.jageum-jung (jgj) is an oriental herbal formula comprising five herbs (melaphis chinensis bell, cremastra variabilis nakai, knoxia valerianoides thorel, euphorbia lathyris l., and moschus moschiferus l.). it has been used for detoxification and treating cancer and inflammatory diseases in china, japan, and korea. however, the mechanism of action of jgj on keratinocyte inflammatory response is poorly understood.201829660465
[cranial features and feeding types of subspecies forms of moschus moschiferus l. (moschidae, cetartiodactyla)].the relationship between the cranial features and feeding types in the musk deer has been studied. according to the results of dispersion and cluster analyses, the six modern subspecies were divided into four trophic (mixed-feeders) subcategories--by the ratio of grass and leaves with a significant fraction of lichens (from 25 to 75%) in their diet. it was established that some morphological features of the skulls of subspecies forms correlate with their feeding specialization and habitat and ca ...201625872401
traditional chinese medicine and sports drug testing: identification of natural steroid administration in doping control urine samples resulting from musk (pod) extracts.the administration of musk extract, that is, ingredients obtained by extraction of the liquid secreted from the preputial gland or resulting grains of the male musk deer (eg, moschus moschiferus), has been recommended in traditional chinese medicine (tcm) applications and was listed in the japanese pharmacopoeia for various indications requiring cardiovascular stimulation, anti-inflammatory medication or androgenic hormone therapy. numerous steroidal components including cholesterol, 5α-androsta ...201322554845
mitochondrial genome of the korean musk deer moschus moschiferus (artiodactyla, ruminantia, moschidae).the complete mitochondrial genome sequence of the korean musk deer moschus moschiferus, which is an endangered species in korea. the circle genome (16,351 bp in size) consists of 13 protein-coding, 22 trna, and 2 rrna genes, and 1 control region (cr), as found in other metazoan animals. the cr was located between the trna(pro) and trna(phe) genes and is 923 bp in length. the typical conserved domains such as etas1 and 2, csb1 and 2, and tas were identified in the cr of m. moschiferus.201020795778
[molecular genetic diversity of musk deer moschus moschiferus l., 1758 (ruminantia, artiodactyla) from the northern subspecies group].genetic diversity within the northern subspecies group of musk deer moschus moschiferus l, 1758 was examined based on the mtdna control region hypervariable fragment (300-bp) sequence polymorphism. nucleotide diversity, constituting 2.6% for the whole sample (n = 34), varied in the range from 0.6 to 1.9% for individual subspecies. maximum values of this index were observed for siberian subspecies (m. m. moschiferus), which had the widest range. genetic similarity between the haplotypes of the mu ...200616915927
synthesis of (r)- and (s)- muscone.(r)-(-)-muscone (3-methylcyclopentadecanone, 1) the key perfumery component isolated from the male musk deer, moschus moschiferus,* was synthesized from the easily available chiral building block, (r)-3-tert-butoxycarbonyl-2-methylpropanoic acid (2), by employing ring-closing olefin metathesis (rcm). antipode (+)-1 was also synthesized in a similar manner from tert-butyl (s)-3-methoxycarbonylbutanoate (10). *(a) walbaum, h. j. j. prakt. chem., 73, 488 (1906); (b) ruzicka, l., further considerati ...200212162565
androstane alkaloids from musk of moschus moschiferus.two androstane alkaloids were isolated from the musk of moschus moschiferus. the structures were elucidated to be 3alpha-ureido-androst-4-en-17-one (1) and 3alpha-ureido-androst-4-en-17beta-ol (2) by two-dimensional nmr analysis (hmqc, 1h-1h cosy, hmbc, and noesy).200212036025
musk deer (moschus moschiferus): reinvestigation of main lipid components from preputial gland secretion.the qualitative and quantitative composition of the principal lipid constituents of siberian musk deer (moschus moschiferus) preputial gland secretion, main odor carriers and potential precursors of odorous substances, was investigated by means of high-performance liquid chromatography. free fatty acids and phenols (10%), waxes (38%), and steroids (38%) were found to be the main groups of the secretion lipids. cholestanol (i), cholesterol (ii), androsterone (iii), δ(4)-3α-hydroxy-17-ketoandroste ...198724301360
structure of hydroxymuscopyridine a and hydroxymuscopyridine b, two new constituents of musk.the structural elucidation of hydroxymuscopyridine a ( 3) and hydroxymuscopyridine b ( 5), two new constituents isolated from musk, moschus moschiferus, is reported.198317405046
species and sex identification of the korean goral (nemorhaedus caudatus) by molecular analysis of non-invasive samples.korean long-tailed goral (nemorhaedus caudatus) is one of the most endangered species in south korea. however, detailed species distribution and sex ratio data on the elusive goral are still lacking due to difficulty of identification of the species and sex in the field. the primary aim of this study was to develop an economical pcr-rflp method to identify species using invasive or non-invasive samples from five korean ungulates: goral (n. caudatus), roe deer (capreolus pygargus), feral goat (ca ...200818679054
[habitats and present situations of 13 rare precious medicinal materials in funiu mountains].the living resources are very abound in the funiu mountains area because of its special geographical position and climate, and there are also many rare precious living beings and chinese medicinal herbs, for example, taxus mairei, ginkgo biloba, gastrodia elata, dendrobium huashanense, physochlaina infunbularis, cypripedium japonicum, dysosma versipellis, moschus moschiferus, megalobatrachus davidanus, succinum, etc, and conscious protection and rational development is an urgent task.199912571910
hiss and snort call types of wild-living giraffes giraffa camelopardalis: acoustic structure and context.vocalization as part of vigilance behaviour is widespread across animal taxa, including ruminants. calls of wild-living giraffes have never been recorded and spectrographically investigated. this study reports the acoustic structure of vigilance-related hiss and snort calls of wild-living giraffes giraffa camelopardalis.201829316966
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