Publications

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protective effect against oxygen reactive species and skin fibroblast stimulation of couroupita guianensis leaf extracts.in this study, hydroalcoholic leaf extracts of couroupita guianensis were examined for antioxidant activity, phytochemical and total phenolic composition, stimulation of human skin fibroblast (hsf) proliferation and uv-absorption. the radical scavenging capacity, reducing power and protection against joint oxidation of linoleic acid and ß-carotene bleaching oxidation in emulsion were used to evaluate the antioxidant activity. the results of this study strongly indicate in vitro antioxidant activ ...201121432721
in vitro antimicrobial activity of traditional plant used in mestizo shamanism from the peruvian amazon in case of infectious diseases.our survey was performed near iquitos (peruvian amazon) and its surroundings and leads us to consider mestizo ethnomedical practices. the plant species reported here are traditionally used for ailments related to microbial infections. inhabitants of various ethnic origins were interviewed, and 52 selected plants extracts were evaluated for their antimicrobial properties against a panel of 36 sensitive and multi-resistant bacteria or yeast. the study aimed at providing information on antimicrobia ...201527013805
multipurpose effectiveness of couroupita guianensis-synthesized gold nanoparticles: high antiplasmodial potential, field efficacy against malaria vectors and synergy with aplocheilus lineatus predators.mosquito-borne diseases represent a deadly threat for millions of people worldwide. according to recent estimates, about 3.2 billion people, almost half of the world's population, are at risk of malaria. malaria control is particularly challenging due to a growing number of chloroquine-resistant plasmodium and pesticide-resistant anopheles vectors. newer and safer control tools are required. in this research, gold nanoparticles (aunps) were biosynthesized using a cheap flower extract of couroupi ...201626732702
evaluation of antiplasmodial activity of medicinal plants from north indian buchpora and south indian eastern ghats.development of resistance against the frontline anti-malarial drugs has created an alarming situation, which requires intensive drug discovery to develop new, more effective, affordable and accessible anti-malarial agents.201525879738
in vitro anti-mrsa activity of couroupita guianensis extract and its component tryptanthrin.couroupita guianensis is known in brazil as 'abricó-de-macaco' and it has some attributes such as: antihypertensive, analgesic and anti-inflammatory activities. this study evaluated the antimicrobial activity of ethanolic extract and fractions of c. guianensis flowers and isolation of bioactive component. these extracts and fractions were subjected to agar diffusion, mic, tlc and bioautography to bacteria, filamentous fungi and yeasts. among the fractions of etoh extract, the dcm fraction was th ...201628013553
optimization of reaction conditions to fabricate nano-silver using couroupita guianensis aubl. (leaf & fruit) and its enhanced larvicidal effect.currently bioactive principles of plants and their nanoproducts have been extensively studied in agriculture and medicine. in this study couroupita guianensis aubl. leaf and fruit extracts were selected for rapid and cost-effective synthesis of silver nanoparticles (leaf-lagnps and fruit-fagnps). various physiological conditions such as temperature, ph, concentration of metal ions, stoichiometric proportion of reaction mixture and reaction time showed influence on the size, dispersity and synthe ...201525062056
antinociceptive activity of fractions from couroupita guianensis aubl. leaves.couroupitaguianensis aubl. (lecythidaceae) is popularly known in brazil as "abricó-de-macaco". infusions or teas obtained from its leaves, flowers, and barks are used in south america for the treatment of several disorders such as pain and inflammatory processes.201019861155
green synthesis of gold nanoparticles and their anticancer activity.as the nano revolution unfolds, it is imperative to integrate nanoscience and medicine. the secret gleaned from nature have led to the generation of biogenic technologies for the fabrication of advanced nanomaterials. present investigation discloses the gold nanoparticles biosynthesizing capability of the flower of pharmacologically important tree couroupita guianensis. rapid, cost-effective, one-step process of synthesis has been achieved. newly genre gold nanoparticles were characterized by in ...201726069504
antioxidant & anticancer activities of isatin (1h-indole-2,3-dione), isolated from the flowers of couroupita guianensis aubl.derivatives of isatin are known to have cytotoxicity against human carcinoma cell lines. this compound therefore, has a potential to be used as a chemotherapeutic agent against cancer. this study was done to investigate the antioxidant and anticancer activities of isatin, extracted from flower of a folklore medicinal plant couroupita guianensis against human promylocytic leukemia (hl60) cells.201223287130
anti-inflammatory activity of ethanol extract and fractions from couroupita guianensis aublet leaves.couroupita guianensis aublet, 'macacarecuia', 'abricó-de-macaco', 'castanha-de-macaco' and 'amêndoa-dos-andes', is found in tropical regions and is widely used in the treatment of tumors, pain, and inflammatory processes.201323313951
'green' biocompatible organic-inorganic hybrid electrospun nanofibers for potential biomedical applications.gold nanoparticles were prepared by green route using couroupita guianensis leaves extract. the green synthesized gold nanoparticles exhibited maximum absorbance at 526 nm in the ultraviolet spectrum. by incorporating the green synthesized gold nanoparticles in poly(vinyl alcohol) matrix, unique green organic-inorganic hybrid nanofibers (poly (vinyl alcohol : )-gold nanoparticles) were developed by electrospinning. contact angle measurements showed that the prepared poly (vinyl alcohol)-gold nan ...201525179829
toxic effects of couroupita guianensis against spodoptera litura (fabricius) (lepidoptera: noctuidae).laboratory experiments were conducted to find out the efficacy of different crude extracts and fractions of couroupita guianensis (lecythidaceae) against spodoptera litura (fabricius). results revealed that hexane, chloroform and ethyl acetate extracts of c. guianensis showed larvicidal and pupicidal activities against s. litura. maximum larvicidal activity (68.66%) was observed in hexane extract at 5.0% concentration followed by chloroform and ethyl acetate extracts, and least lc50 value of 2.6 ...201526013016
evaluation of silver nanoparticles synthetic potential of couroupita guianensis aubl., flower buds extract and their synergistic antibacterial activity.the present investigation demonstrates couroupita guianensis flower buds extract mediated synthesis of stable silver nanoparticles (agnps). instant formation of agnps was primarily confirmed by the appearance of yellowish brown colour and characteristic silver spr band in the uv-visible spectrum. elemental and crystalline natures of the agnps were identified from edx and xrd pattern, respectively. spherical morphology and the mono-disparity were revealed from tem and afm images. the particle siz ...201628330162
in vitro propagation, micromorphological studies and ex vitro rooting of cannon ball tree (couroupita guianensis aubl.): a multipurpose threatened species.in vitro propagation methods using seeds and nodal segments of a 21-year old couroupita guianensis - a medicinally important but threatened tree have been developed. hundred percent of the seeds germinated on half strength murashige and skoog (ms) medium with 2.0 mg l(-1) indole-3 butyric acid (iba). nodal segments were found most suitable for the establishment of cultures. about 90 % explants responded and 4.1 ± 0.23 shoots per node were induced after five weeks of inoculation on ms medium +4.0 ...201627186027
target and non-target toxicity of botanical insecticide derived from couroupita guianensis l. flower against generalist herbivore, spodoptera litura fab. and an earthworm, eisenia foetida savigny.botanical insecticides may provide alternatives to synthetic insecticides for controlling spodoptera litura (f.) and they are target specific, biodegradable, and harmless to mammals. eight natural chemical compounds with larvicidal activity were identified from fraction f6 of c. guianensis flower extract. probit analysis of 95% confidence level exposed an lc50 of 223ppm against s. litura third instar larvae. the growth and development of s. litura was affected in sub-lethal concentrations of fra ...201627476000
impact of auxins on vegetative propagation through stem cuttings of couroupita guianensis aubl.: a conservation approach.the present study explores the potential of exogenous auxins in the development of adventitious shoots and roots from shoot cuttings of couroupita guianensis (nagalingam), a threatened tree. experiments were conducted to assess the effect of various concentrations of auxins on shoot and root morphological traits of stem cuttings in the greenhouse. amongst the auxins tested, significant effects on number of shoot buds' induction and their growth were observed with α-naphthalene acetic acid (naa) ...201628083155
identification of potential antioxidant indices by biogenic gold nanoparticles in hyperglycemic wistar rats.oxidative stress is a crucial factor in diabetes, where the abnormal metabolic ambience leads to hyperglycemia resulting in the onset of several vascular complications. under homeostasis, innate antioxidants efficiently inhibit the oxidative stress, thereby restrain further progression of diabetes. in the present study, a potential antioxidant marker was identified from hepatic tissue of diabetic wistar rats after oral administration of biogenic gold nanoparticles (gnps). diabetic animals treate ...201728110133
evolution of lecythidaceae with an emphasis on the circumscription of neotropical genera: information from combined ndhf and trnl-f sequence data.the lecythidaceae comprise a pantropical family best known for the edible seeds of the brazil nut (bertholletia excelsa) and the cannon-ball tree (couroupita guianensis), which is planted as a botanical curiosity in subtropical and tropical gardens. in addition, species of the family are often among the most common in neotropical forests, especially in the amazon basin. the brazil nut family is diverse and abundant in the amazon and is considered to be an indicator of undisturbed or scarcely dis ...200721636402
a search for phylogenetically informative wood characters within lecythidaceae s.l.the wood structure of 71 species representing 24 genera of the pantropical lecythidaceae s.l., including the edible brazil nuts (bertholletia excelsa) and the spectacular cannon-ball tree (couroupita guianensis), was investigated using light and scanning electron microscopy. this study focused on finding phylogenetically informative characters to help elucidate any obscure evolutionary patterns within the family. the earliest diverging subfamily napoleonaeoideae has mixed simple/scalariform vess ...200721636419
antimicrobial, antimycobacterial and antibiofilm properties of couroupita guianensis aubl. fruit extract.couroupita guianensis aubl. (lecythidaceae) is commonly called ayahuma and the cannonball tree. it is distributed in the tropical regions of northern south america and southern caribbean. it has several medicinal properties. it is used to treat hypertension, tumours, pain, inflammatory processes, cold, stomach ache, skin diseases, malaria, wounds and toothache.201223206492
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