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parasites of south african wildlife. vii. helminths of suni, neotragus moschatus, in natal.the helminths of 4 suni, neotragus moschatus, from the tembe national elephant park, kwazulu, natal, were collected, counted and identified. cooperia hungi, a race of cooperia rotundispiculum, haemonchus vegliai, setaria cornuta, a skrjabinema sp., strongyloides papillosus, trichostrongylus anomalus and trichostrongylus deflexus are new parasite records for suni in africa. megacooperia woodfordi was recovered for the first time from south african antelope.19912052316
x chromosome evolution in the suni and eland antelope: detection of homologous regions by fluorescence in situ hybridization and g-banding.comparative cytogenetics and fluorescence in situ hybridization (fish) were used to track structural rearrangements in the x chromosomes of two african antelope species, the eland (taurotragus oryx; tribe tragelaphini) and the suni (neotragus moschatus; tribe neotragini). using two microdissected cattle chromosome painting probes (one specific for xp-containing sequences corresponding to xp24-->p12 of the cattle x, and one specific for xq-containing sequences corresponding to xq12-->qter), we sh ...19979284920
cytochrome b phylogeny of the family bovidae: resolution within the alcelaphini, antilopini, neotragini, and tragelaphini.the family bovidae is characterized by an incomplete fossil record for the period during which most bovid subfamilies emerged. this, coupled to extensive morphological convergence among species, has given rise to inconsistencies in taxonomic treatments, especially at the tribal and subfamilial levels. in an attempt to clarify some of these issues we analyzed the complete mtdna cytochrome b gene (1140 bp) from 38 species/subspecies representing at least nine tribes and six subfamilies. specific e ...199910222159
phylogenetic relationships in the bovid subfamily antilopinae based on mitochondrial dna sequences.a molecular phylogeny of the subfamily antilopinae was determined using the two mitochondrial dna (mtdna) genes cytochrome b and cytochrome c oxidase iii. the tribe antilopini is monophyletic with antidorcas marsupialis and litocranius walleri basal to the large genus gazella. antilope cervicapra falls within gazella. this placement would either make gazella paraphyletic or require that the genus name gazella be changed to antilope. gazella thomsonii is supported as a subspecies of g. rufifrons. ...199910381312
the tribal radiation of the family bovidae (artiodactyla) and the evolution of the mitochondrial cytochrome b gene.the nucleotide sequence of the complete mitochondrial cytochrome b gene has been determined and compared for 51 species of the family bovidae and 10 potential pecoran and tragulid outgroups. a detailed saturation analysis at each codon position relative to the maximum parsimony procedure indicates that all transitions on third codon positions do not accumulate in a similar fashion: c-t are more saturated than a-g substitutions. the same trend is observed for second positions but not for first po ...199910603253
the pyc plasmids, a series of cassette-based yeast plasmid vectors providing means of counter-selection.a series of 24 general-purpose yeast plasmid vectors has been constructed. the plasmid series is composed of inter-replaceable cassettes, allowing for easy interconversion of plasmid types. in addition to the usual replication origins, selectable markers and multiple cloning sites (mcs), cassettes dedicated to counter-selection have been constructed. a pair of unique 8 bp restriction enzyme recognition sites flank each type of cassette, fsei in the case of yeast replication origins, asci in the ...200010923025
molecular insights into the evolution of the family bovidae: a nuclear dna perspective.the evolutionary history of the family bovidae remains controversial despite past comprehensive morphological and genetic investigations. in an effort to resolve some of the systematic uncertainties within the group, a combined molecular phylogeny was constructed based on four independent nuclear dna markers (2,573 characters) and three mitochondrial dna genes (1,690 characters) for 34 bovid taxa representing all seven of the currently recognized bovid subfamilies. the nuclear dna fragments were ...200111420362
immunity to the bacteriocin sublancin 168 is determined by the suni (yolf) protein of bacillus subtilis.bacillus subtilis strain 168 produces the extremely stable lantibiotic sublancin 168, which has a broad spectrum of bactericidal activity. both sublancin 168 production and producer immunity are determined by the spbeta prophage. while the suna and sunt genes for sublancin 168 production have been known for several years, the genetic basis for sublancin 168 producer immunity has remained elusive. therefore, the present studies were aimed at identifying an spbeta gene(s) for sublancin 168 immunit ...200919047653
vivid valleys, pallid peaks? hypsometric variations and rural-urban land change in the central peruvian andes.what happens to the land cover within the hinterland's altitudinal belts while central andean cities are undergoing globalization and urban restructuring? what conclusions can be drawn about changes in human land use? by incorporating a regional altitudinal zonation model, direct field observations and gis analyses of remotely sensed long term data, the present study examines these questions using the example of huancayo metropolitano - an emerging peruvian mountain city of 420,000 inhabitants, ...201223564987
new world species of the genus calliscelio ashmead (hymenoptera, platygastridae, scelioninae).the genus calliscelio ashmead is presumed to be a diverse group of parasitoids of the eggs of crickets (orthoptera: gryllidae). a least one species has been found to be an important factor in depressing cricket pest populations. the new world species of calliscelio are revised. forty-two species are recognized, 3 are redescribed: calliscelio bisulcatus (kieffer), calliscelio laticinctus ashmead, calliscelio rubriclavus (ashmead), comb. n.; and 38 are described as new: calliscelio absconditum che ...201728325969
sem analysis of the integrity of resected root apices of cadaver and extracted teeth after ultrasonic root-end preparation at different intensities.to compare the integrity of root apices of cadaver and extracted teeth after resection, ultrasonic root-end cavity preparation at medium and low ultrasonic power settings and retrieval.200515876295
longitudinal study on microleakage of three root-end filling materials by the fluid transport method and by capillary flow porometry.(i) to compare the root-end sealing ability of irm caps (irm), fuji ix capsules (fuji ix) and pro root mta tooth-coloured formula (mta) in teeth obtained from cadavers. (ii) further research on leakage study methodology by means of comparison of the fluid transport method (ftm) and capillary flow porometry (cfp).200515667635
commercial milling of suni bug (eurygaster spp.) damaged wheat.in some wheat growing countries, considerable quantities of commercial wheat are rendered unusable in standard milling because of pre-harvest damage of the grain by protease-injecting insects. the possibility of mitigating the detrimental effects of bug damage by eliminating the mill streams of lower quality from straight run flour was investigated. the changes in the amount of damaged kernels by cleaning and washing prior to milling were also examined. dry cleaning decreased the level of insect ...200211890050
mammalian exocrine secretions. xvii: chemical characterization of preorbital secretion of male suni, neotragus moschatus.gas chromatographic and gas chromatographic-mass spectrometric techniques were employed to identify 83 compounds, including alkanes, alkenes, aldehydes, 2-methylalkanes, carboxylic acids, 1-alkyl formates and alken-1-yl formates, benzoic acid, and cholesterol, in the preorbital secretion of the male suni, neotragus moschatus. dimethyl disulfide derivatization and lithium aluminum hydride reduction were used to determine the position of double bonds and to confirm the identity of the functional g ...200211868681
digestive efficiency in two small, wild ruminants: the dik-dik and suni antelopes.a comparative study, using six dik-dik and eight suni antelope, was undertaken to identify similarities and differences that may exist in the digestive process of these two small, east african ruminant browsers. the suni antelope was the more select feeder, preferring the native, grewia sinilis leaves over that of lucerne hay. daily forage consumption rate, per unity body weight, was greater in the dik-dik (40.4 g/kg) than for the suni (30.6 g/kg), while daily fluid intake was considerably less ...199910629956
efficacy of diagnostic upper-node procedures during laryngectomy for glottic carcinoma.regional recurrence of glottic squamous cell carcinoma was evaluated in patients with a clinically n0 neck who underwent selective upper-node dissection (sund) or selective upper-node inspection (suni; surgical visualization and palpation of jugular lymph nodes at levels ii and iii) during (salvage) laryngectomy.200918778803
patient discomfort in bitewing examination with film and four digital receptors.the aim was to compare patient discomfort during bitewing examination using five intra-oral receptors: a conventional film, a storage phosphor plate with a new soft cover, an already manufactured and sold sensor with a wire and two square and two rounded corners, a new version of a previously developed sensor with a wire and four square corners, and a newly developed sensor with a wire and four rounded corners. 60 patients participated in the study. the five receptors [a kodak paper pack film (e ...201222517998
benchmarking effects of mtor, pi3k, and dual pi3k/mtor inhibitors in hepatocellular and renal cell carcinoma models developing resistance to sunitinib and sorafenib.to evaluate first-generation rapamycin analogs (everolimus, temsirolimus, and rapamycin) and second-generation drugs inhibiting mtor kinase (azd-8055), pi3k (bkm-120) or both (bez-235 and gdc-0980) in hepatocellular carcinoma (hcc) and renal cell carcinoma (rcc) cells characterized for acquired resistance to sorafenib or sunitinib.201323479136
simultaneous analysis of anticancer agents bortezomib, imatinib, nilotinib, dasatinib, erlotinib, lapatinib, sorafenib, sunitinib and vandetanib in human plasma using lc/ms/ms.a new liquid chromatography-tandem mass spectrometry (lc-ms/ms) method, performed by electrospray ionization in positive mode using a triple quadrupole mass spectrometry, has been developed and validated for the simultaneous determination of bortezomib (bort), dasatinib (dasa), imatinib (imat), nilotinib (nilo), erlotinib (erlo), lapatinib (lapa), sorafenib (sora), sunitinib (suni) and vandetanib (vand) in human plasma. separation is achieved on an hypersil gold(®) pfp column using a gradient el ...201323562906
emmprin promotes angiogenesis, proliferation, invasion and resistance to sunitinib in renal cell carcinoma, and its level predicts patient outcome.extracellular matrix metalloproteinase inducer (emmprin) has been reported to play crucial roles, including in angiogenesis, in several carcinomas. however, the correlation between emmprin levels and angiogenesis expression profile has not been reported, and the role of emmprin in renal cell carcinoma (rcc) is unclear. in the present study, we evaluated the association of emmprin with angiogenesis, its value in prognosis, and its roles in rcc.201324073208
the enigmatic marine reptile nanchangosaurus from the lower triassic of hubei, china and the phylogenetic affinities of hupehsuchia.the study of the holotype and of a new specimen of nanchangosaurus suni (reptilia; diapsida; hupehsuchia) revealed a suite of hitherto unrecognized characters. for example, nanchangosaurus has bipartite neural spines and its vertebral count is nearly identical to that of hupehsuchus. it differs from the latter in having poorly developed forelimbs despite the advanced ossification in the rest of the skeleton. other differences all pertain to hupehsuchian plesiomorphies retained in nanchangosaurus ...201425014493
estimating species richness and modelling habitat preferences of tropical forest mammals from camera trap data.medium-to-large mammals within tropical forests represent a rich and functionally diversified component of this biome; however, they continue to be threatened by hunting and habitat loss. assessing these communities implies studying species' richness and composition, and determining a state variable of species abundance in order to infer changes in species distribution and habitat associations. the tropical ecology, assessment and monitoring (team) network fills a chronic gap in standardized dat ...201425054806
the "sowing of concrete": peri-urban smallholder perceptions of rural-urban land change in the central peruvian andes.policy makers concerned with the peri-urban interface find their greatest challenges in the rapid urban growth of developing mountain regions, since limitations caused by relief and altitude often lead to an increased competition between rural and urban land use at the valley floors. in this context, little attention has been paid to the affected agriculturalists' perceptions of peri-urban growth-important information required for the realization of sustainable land use planning. how is the proc ...201425844006
effects of tgf-beta signalling inhibition with galunisertib (ly2157299) in hepatocellular carcinoma models and in ex vivo whole tumor tissue samples from patients.galunisertib (ly2157299) is a selective atp-mimetic inhibitor of tgf-β receptor (tβr)-i activation currently under clinical investigation in hepatocellular carcinoma (hcc) patients. our study explored the effects of galunisertib in vitro in hcc cell lines and ex vivo on patient samples. galunisertib was evaluated in hepg2, hep3b, huh7, jhh6 and sk-hep1 cells as well as in sk-hep1-derived cells tolerant to sorafenib (sk-sora) and sunitinib (sk-suni). exogenous stimulation of all hcc cell lines wi ...201526057634
a large, short-armed, winged dromaeosaurid (dinosauria: theropoda) from the early cretaceous of china and its implications for feather evolution.the famous 'feathered dinosaurs' from the early cretaceous of liaoning province, northeastern china, include several dromaeosaurids, which are among the closest relatives of birds. most of these are small-bodied taxa with long arms and broad wings comprised of vaned feathers, but a single specimen (the holotype of tianyuraptor) belongs to a much larger individual with reduced forelimbs, which unfortunately lacks any preserved integument. we describe a new specimen of large-bodied, short-armed li ...201526181289
prognostic factors for survival in metastatic renal cell carcinoma patients with brain metastases receiving targeted therapy.the primary objective of our study was to examine the clinical outcomes and prognosis of patients with metastatic renal cell carcinoma (mrcc) with brain metastases (bms) receiving targeted therapy.201828731496
enhanced temperature stability in the r-t phase boundary with dominating intrinsic contribution.in this study, 0.96knnsx-0.01sz-0.03bnz ceramics (x = 0-0.08) were used as examples to illustrate the effects of phase boundaries on strain property and temperature stability. the addition of sb5+ resulted in a rhombohedral-tetragonal (r-t) phase boundary at x = 0.05-0.07, as confirmed by temperature-dependent raman spectra. in the r-t region, an improved piezoelectric constant (d33 = 390-440 pc n-1) and high unipolar strain (suni = 0.14-0.15%) were observed due to the dominating intrinsic contr ...201830027946
an alternative way to enhance piezoelectricity and temperature stability in lead-free sodium niobate piezoceramics.to further balance the relationship between piezoelectricity and temperature stability, the (0.975 - y)nanbo3- ybatio3-0.025bazro3 ( y = 0-0.20) ceramics are developed by constructing a wide tetragonal phase region. effects of batio3 on the relationships among phase structure, electrical properties, and temperature dependence are investigated. with increasing batio3 contents, the ceramics endure the structural evolutions from orthorhombic phase to tetragonal phase, and then to relaxor cubic phas ...201830059224
new species of anaptomecus simon, 1903 (araneae: sparassidae) from colombia, with an identification key for all known species of the genus.the huntsman spider genus anaptomecus was proposed by simon (1903) to include the type species, a. longiventris simon, 1903, described from a juvenile male collected in cayambé (san pedro de cayambé), pichincha, ecuador. mello-leitão (1940) described a second species, a. rufescens, from a female collected in essequibo river, guyana. the genus remained unstudied until the early 2000's when jäger et al. (2009) described the adult male and female of a. longiventris and transferred a. rufescens to s ...201830486181
differential expression of a prophage-encoded glycocin and its immunity protein suggests a mutualistic strategy of a phage and its host.sublancin 168 is a highly potent and stable antimicrobial peptide secreted by the gram-positive bacterium bacillus subtilis. production of sublancin gives b. subtilis a major competitive growth advantage over a range of other bacteria thriving in the same ecological niches, the soil and plant rhizosphere. b. subtilis protects itself against sublancin by producing the cognate immunity protein suni. previous studies have shown that both the suna gene for sublancin and the suni immunity gene are en ...201930808982
a simple and fast lc-ms/ms method for the routine measurement of cabozantinib, olaparib, palbociclib, pazopanib, sorafenib, sunitinib and its main active metabolite in human plasma.targeted therapies such as cabozantinib (cabo), pazopanib (pazo), sorafenib (sora), sunitinib (suni) and its main active metabolite n-desethyl-sunitinib (dst-suni), olaparib (ola) and palbociclib (palbo) display large pharmacokinetics variability impacting their responses in terms of efficacy or toxicity. for the monitoring of these drugs, an analytical method allowing to routinely measure their concentrations in human plasma is needed. such a method has been developed and validated and is prese ...201931678788
when parks work: effect of anthropogenic disturbance on occupancy of tropical forest mammals.protected areas (pas) in the tropics are vulnerable to human encroachment, and, despite formal protection, they do not fully mitigate anthropogenic threats to habitats and biodiversity. however, attempts to quantify the effectiveness of pas and to understand the status and changes of wildlife populations in relation to protection efficiency remain limited. here, we used camera-trapping data collected over 8 consecutive years (2009-2016) to investigate the yearly occurrences of medium-to-large ma ...202032489618
allozyme divergence within the bovidae.we describe a phylogeny of the bovidae based on 40 allozyme loci in 27 species, representing 10 of the 14 bovid tribes described by vrba (1985). giraffe represented a related family (giraffidae). a phenogram was derived using the unweighted pair-group method with arithmetic means (upgma), based on nei's genetic distances (nd) between species. a tree was also derived using the neighbor-joining technique, also based on nd. to provide a cladistic interpretation, the data were analyzed by a maximum ...199028564432
purification and characterisation of an inhibitor of a cathepsin b-like proteinase from sunflower seed.cathepsin b is a vitally important enzyme in various physiological processes and in tumor invasion and metastasis. a cathepsin b inhibitor, hcb-suni, was identified and purified from sunflower seeds, helianthus annuus, using ammonium sulfate precipitation and two steps of conventional chromatography. the molecular mass of hcb-suni was estimated to be 12 kda by sds-page and 12.32 kda by maldi tof ms. its n-terminal amino acid sequence was determined to be: pyggggtesg. hcb-suni not only inhibited ...200617059177
a complex of cardicola short, 1953 (digenea: aporocotylidae) species infecting the milkfish chanos chanos forsskål (gonorynchiformes), with descriptions of two new species.two new species of cardicola short, 1953 are described from the milkfish, chanos chanos forsskål (gonorynchiformes: chanidae), obtained from off lizard island on the northern great barrier reef (gbr) and north stradbroke island in southeast queensland. these are the first known blood flukes from this order of fishes. cardicola suni n. sp. differs from all other cardicola spp. by a combination of a large ovoid oral sucker surrounding a subterminal mouth, recurved tegumental spines up to 16 μm lon ...201627743234
improved production of sublancin via introduction of three characteristic promoters into operon clusters responsible for this novel distinct glycopeptide biosynthesis.sublancin is a novel and distinct antimicrobial glycopeptide that can be used as an alternative to conventional antibiotics. the reported production of sublancin by bacillus subtilis 168 is poor because transcriptional regulatory circuit of suna, a gene that encodes presublancin, is complex and difficult to control.201525879813
detection of non-cavitated approximal caries lesions in digital images from seven solid-state receptors with particular focus on task-specific enhancement filters. an ex vivo study in human teeth.the aim of this study was to compare detection of non-cavitated approximal caries lesions in images from seven solid-state intraoral digital receptors, with particular focus on two task-specific enhancement filters. one hundred and sixty approximal non-cavitated surfaces were radiographed under standardized conditions using the following seven intraoral solid-state digital receptors: two cmos systems, schick cdr-aps, and kodak rvgui; and five ccd systems: visualix, vistaray, dixi2, sidexis, and ...200818210170
ticks (acari: ixodidae) of small antelopes: steenbok, raphicerus campestris and suni, neotragus moschatus.during surveys on the tick burdens of various wildlife species in south africa, nine small antelopes became available for study. six of these were steenbok, raphicerus campestris and three sunis, neotragus moschatus, and their tick burdens are recorded here. the steenbok were examined in three nature reserves and harboured nine tick species. the sunis were examined in a fourth reserve and were infested with eight species. the steenbok and sunis were generally infested with the immature stages of ...200617058446
ex vivo detection and enumeration of human antigen-specific cd8+ t lymphocytes using antigen delivery by a recombinant vaccinia expression vector and intracellular cytokine staining.we describe an intracellular cytokine staining, flow cytometry based technique for quantitative and qualitative assessment of cd8+ t lymphocyte-mediated antigen specific immune responses. this adaptation of the technique first described by suni et al. [j. immunol. methods, 212 (1998) 89; cytometry, 40 (2000) 60] utilises a recombinant vaccinia expression vector to deliver the test antigen to the mhc class i processing pathway. this allows the measurement of antigen-specific cd8+ t cell responses ...200211983230
an ethnobotanical study of the traditional medicine of the mestizo people of suni miraño, loreto, peru.research on the ethnobotany of mestizos in suni miraño in 1994 documented 60 plant species used for medicinal purposes. some cultural data on traditional healing and etiology were also collected. of these 60 species, 31 were submitted to antibacterial and antifungal assays in the presence and absence of uv light and a number of species were shown to be active.19968887022
epidemiological survey of rheumatic heart disease among school children in the shimla hills of northern india: prevalence and risk factors.to determine the prevalence of rheumatic heart disease (rhd) and study the relationship of this disease to factors such as age, sex, housing, and socioeconomic status in shimla town and the adjoining rural area.19968762356
reproductive anatomy, manipulation of ovarian activity and non-surgical embryo recovery in suni (neotragus moschatus zuluensis).marked disparity in the uterine horn dimensions and relative degrees of caruncle development in suni suggested that exclusive or predominant dextral implantation occurs in association with bilateral ovulatory activity. daily urinary measurements of pregnanediol-3 alpha-glucuronide revealed an oestrous cycle of approximately 21 days in length. ovarian activity was controlled for synchronization of oestrus by using progestagen-impregnated intravaginal sponges and multiple ovulations were induced b ...19902325018
evaporative water loss in two small african antelopes: the dik-dik and the suni. 19763376
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