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antiviral activity against human immunodeficiency virus type 1 (hiv-1) and type 2 (hiv-2) of ethnobotanically selected ethiopian medicinal plants.ethiopian medicinal plants used for the treatment of a variety of ailments including infectious diseases were screened for activity against human immunodeficiency virus type 1 (hiv-1) and type 2 (hiv-2). seventy-one polar and nonpolar extracts derived from 21 plants belonging to 14 families were tested for inhibition of viral replication using hiv-1 (iii(b)) and hiv-2 (rod) strains. selective inhibition of viral growth was assessed by the simultaneous determination of the in vitro cytotoxicity o ...200111180526
molecular analysis of cotton leaf curl virus-sudan reveals an evolutionary history of recombination.monopartite begomoviral dnas (2761 bp) were cloned and sequenced from field cotton, okra, and sida alba, from gezira, and field okra from shambat. comparison of the four apparent full-length begomoviral dnas revealed 99.3-99.5% shared nucleotide (nt) identity, indicating that they are the same viral species, hereafter, referred to as cotton leaf curl virus-sudan (clcuv-sd). host range studies revealed that the field okra isolate of clcuv-sd was whitefly-transmissible from okra to okra, m. parvif ...200212086146
microcyclic rusts of hollyhock ( alcea rosea ).rust fungi infecting hollyhock and other plants in malveae are frequently intercepted at ports of entry to the usa, particularly puccinia malvacearum and p. heterogenea. these two species can be difficult to distinguish and can be further confused with other, less common species of microcyclic rust fungi infecting hollyhock: p. heterospora, p. lobata, p. platyspora, and p. sherardiana. molecular phylogenetic analysis revealed that p. malvacearum and p. heterogenea are closely related, along with ...201526734550
hollyhock-disease and the cotton-plant. 188517839872
high molecular weight acidic polysaccharides from malva sylvestris and alcea rosea.leaves and flowers of malva sylvestris and alcea rosea (malvaceae) were compared by determination of the swelling index as well as the content and viscosity of their mucilages. the investigations showed mucilage from flowers of alcea to be superior to mucilages from leaves or flowers from malva. high molecular weight acidic polysaccharides (hmwaps) were isolated from the mucilages of leaves and flowers of both species. the molecular weight of all hmwaps was in a range of 1.3 to 1.6 x 10(6) d. hm ...19989810269
alcea rosea root extract as a preventive and curative agent in ethylene glycol-induced urolithiasis in rats.alcea rosea l. is used in asian folk medicine as a remedy for a wide range of ailments. the aim of the present study was to investigate the effect of hydroalcoholic extract of alcea rosea roots on ethylene glycol-induced kidney calculi in rats.201222701236
association of a distinct strain of hollyhock yellow vein mosaic virus and ludwigia leaf distortion betasatellite with yellow vein mosaic disease of hollyhock (alcea rosea) in india.a distinct strain of hollyhock yellow vein mosaic virus (hoyvmv) and ludwigia leaf distortion betasatellite (luldb) were associated with yellow vein mosaic of hollyhock. the viral dna genome (jq911766) and betasatellite (jq408216) shared highest nucleotide sequence identity (89.2 %) with hoyvmv (the only available sequence in genbank) and 92 % identity with luldb. agroinfiltration of hoyvmv and luldb induced yellow vein mosaic symptoms on hollyhock, thereby demonstrating causality of the disease ...201424810100
hypoglycemic activity evaluation and chemical study on hollyhock flowers.hollyhock (althaea rosea (linn.) cavan) belongs to althaea genus, malvaceae family, is a perennial garden plant distributed throughout the world in warm temperate and tropical regions, which was used as anti-diabetes ingredient in traditional chinese medicine. in the process of our research, ethanolic extract of hollyhock flower (hfe) was found to decrease serum triglyceride and glucose levels significantly in kk-a(y) mice after oral administration for 8weeks. meanwhile, gene expressions on ampk ...201525677352
inhibitory effects of physalis alkekengi l., alcea rosea l., bunium persicum b. fedtsch. and marrubium vulgare l. on mushroom tyrosinase.the key enzyme in the process of melanin biosynthesis is tyrosinase. skin hyperpigmentation and browning of foods are undesirable phenomena which tyrosinase represents. therefore, tyrosinase inhibitors have been used increasingly for medicinal and cosmetic products.201525866725
the effect of hollyhock (althaea officinalis l) leaf compresses combined with warm and cold compress on breast engorgement in lactating women: a randomized clinical trial.breast engorgement affects lactation. the present study was conducted to determine the effect of hollyhock combined with warm and cold compresses on improving breast engorgement in lactating women. participants included 40 women with breast engorgement divided into intervention and control groups, with participants in both groups being applied routine interventions and warm compress before nursing and a cold compress after nursing; however, the intervention group was also applied hollyhock compr ...201726603219
an ornamental plant targets epigenetic signaling to block cancer stem cell-driven colon carcinogenesis.phytochemicals modulate key cellular signaling pathways and have proven anticancer effects. alcea rosea(ar; hollyhock) is an ornamental plant with known anti-inflammatory properties. this study explored its role as an anticancer agent. the ar seed extract (ar extract) inhibited proliferation and colony formation in a dose- and time-dependent manner and promoted apoptosis as was evidenced by cleavage of parp and increased expression of bax accompanying reduced levels of bcl-xl protein in hct116 a ...201626785732
first report of an alphasatellite associated with okra enation leaf curl virus.an alphasatellite dna associated with okra enation leaf curl virus (oelcuv) which causes enation and leaf curling in okra (abelmoschus esculentus) plants was characterized. the full-length dna comprises 1,350 nucleotides and shows typical genome organization of an alphasatellite. it shows the highest nucleotide sequence identity (79.7 %) to hollyhock yellow vein virus-associated symptomless alphasatellite (hoyvsla). this is the first report of the association of an alphasatellite with oelcuv fro ...201323475199
molecular diversity of cotton leaf curl gezira virus isolates and their satellite dnas associated with okra leaf curl disease in burkina faso.okra leaf curl disease (olcd) is a major constraint on okra (abelmoschus esculentus) production and is widespread in africa. using a large number of samples representative of the major growing regions in burkina faso (bf), we show that the disease is associated with a monopartite begomovirus and satellite dna complexes. twenty-three complete genomic sequences of cotton leaf curl gezira virus (clcugv) isolates associated with olcd, sharing 95 to 99% nucleotide identity, were cloned and sequenced. ...201020178575
naturally occurring anti-cancer agents targeting ezh2.natural products are considered as promising tools for the prevention and treatment of cancer. the enhancer of zeste homolog 2 (ezh2) is a histone methyltransferase unit of polycomb repressor complexes such as prc2 complex that has oncogenic roles through interference with growth and metastatic potential. several agents targeting ezh2 has been discovered but they often induce side effects in clinical trials. recently, ezh2 has emerged as a potential target of natural products with documented ant ...201728323035
a severe symptom phenotype in tomato in mali is caused by a reassortant between a novel recombinant begomovirus (tomato yellow leaf curl mali virus) and a betasatellite.tomato production in west africa has been severely affected by begomovirus diseases, including yellow leaf curl and a severe symptom phenotype, characterized by extremely stunted and distorted growth and small deformed leaves. here, a novel recombinant begomovirus from mali, tomato yellow leaf curl mali virus (tylcmlv), is described that, alone, causes tomato yellow leaf curl disease or, in combination with a betasatellite, causes the severe symptom phenotype. tylcmlv is an old world monopartite ...200919400843
the compounds from the hollyhock extract (althaea rosea cav. var. nigra) affect the aromatization in rat testicular cells in vivo and in vitro.among medicinal plants, extract from the hollyhock flowers is a source of antocyanides and flavonoids. the latter compounds belong, among others, to phytoestrogens (plant-derived dietary estrogens). the important role of estrogens in the testis is now well documented, and phytoestrogens, which may act as estrogen agonists or estrogen antagonists can also alter the reproductive function of the male. the aim of this study was to show whether the exposure of male rats to the aqueous hollyhock extra ...200212502186
association of a recombinant cotton leaf curl bangalore virus with yellow vein and leaf curl disease of okra in india.a begomovirus isolate (oy136a) collected from okra plants showing upward leaf curling, vein clearing, vein thickening and yellowing symptoms from bangalore rural district, karnataka, india was characterized. the sequence comparisons revealed that, this virus isolate share highest nucleotide identity with isolates of cotton leaf curl bangalore virus (clcubv) (ay705380) (92.8 %) and okra enation leaf curl virus (81.1-86.2 %). this is well supported by phylogentic analysis showing, close clustering ...201324426275
[determination of trace elements in hollyhock by microwave digestion-faas].hollyhock powder was digested by microwave digestion before determination. the eight trace elements, fe, cu, zn, mn, k, ni, ca and mg, in hollyhock were determined by microwave faas. standard curves method was used for the determination. the samples were digested with hno3. the conditions of digestion were optimized. the effect of different microwave digestion conditions on the analysis results was reviewed, and the optimal condition for using atomic absorption spectrophotometry was determined. ...200920102006
root-knot nematode problem of some winter ornamental plants and its biomanagement.a microplot study under field conditions was carried out during 2 consecutive years to assess the effect of root-knot nematode infection (2,000 meloidogyne incognita eggs/kg soil) on three winter ornamental plants: hollyhock (althea rosea), petunia (petunia hybrida), and poppy (papaver rhoeas). effects of root-dip treatment with the biocontrol agents pochonia chlamydosporia, bacillus subtilis, and pseudomonas fluorescens and the nematicide fenamiphos were tested. the three ornamental species wer ...200519262861
the effects of alcea rosea l., malva sylvestris l. and salvia libanotica l. water extracts on the production of anti-egg albumin antibodies, interleukin-4, gamma interferon and interleukin-12 in balb/c mice.polysaccharides obtained from certain plants have been reported to have immunomodulatory properties. as a consequence of these reports the aim of this study was to investigate some immunomodulatory properties of water extracts of alcea rosea l. (are), malva sylvestris l. (mse) and salvia libanotica l. (sle).groups of egg albumin (ea)-immunized and -non-immunized balb/c mice were treated with the carbohydrate-rich water extracts. mice from each group were bled and their spleens removed at 3, 6 an ...200818688815
the influence of hollyhock extract administration on testicular function in rats.it has been reported, recently that an aqueous extract from hollyhock flowers (althaea rosea cav. varietas nigra) induces weak metabolic changes in rat testes. in the present study, the in vivoinfluence of a methanolic extract was investigated on the metabolism and morphology of the rat testis. to this end, histochemical, morphometric and radioimmunological methods were used. the rats drank the extract at a dose of 100 mg/day for 7 weeks. the histochemical activities of glucose-6-phosphate dehyd ...200415609085
histochemical changes in the leydig cells of rats drinking the aqueous hollyhock extract.the effect of aqueous hollyhock flower (althaea rosea cav. var. nigra) extract on the rat leydig cell metabolism and morphology was studied using histochemical, morphometric and radioimmunological methods. the rats were drinking the extract for 30 days (group a1) and for 180 days (group a2). leydig cells of group a1 manifested marked increase in the 3beta-hsd, g6pd and nadpd activities and in the khanolkar reaction intensity. these findings were accompanied by the increase in the volume of leydi ...200111374834
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