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effect of unilateral lesion of amygdala on unmanifested response to matatabi (actinidia polygama) in cats.the experiment was designed to elucidate the question whether the unilateral ablation of the amygdala significantly affects sexual behavior or not. for this purpose, the effect of the unilateral amygdalectomy upon matatabi-response was investigated in the cat (r-cat), particularly in cats which showed unmanifested matatabi-response in the innate status (nr-cat). following the unilateral damage to the amygdala, nr-cats showed a significant manifestation in their matatabi-response behavior, while ...19751129764
[matatabi (actinidia polygama miq.)--isolation and structure of its biologically active components]. 19675341300
[matatabi (actinidia polygama)--pharmacological studies on its components]. 19676068343
antiproliferative effects of small fruit juices on several cancer cell lines.juices prepared from small fruits, mainly growing in the northern part of japan, were studied in an attempt to explore the feasibility of an assay that screens cytotoxic properties. screening of 43 small fruit juices indicated that actinidia polygama maxim., rosa rugosa thunb., vaccinium smallii a. gray and sorbus sambucifolia roem, strongly inhibited the proliferation of all cancer cell lines examined and yet these juices were substantially less cytotoxic toward normal human cell lines.200011205259
characterization of (1'r,4s,4ar,7s,7ar)-dihydronepetalactol as a semiochemical for lacewings, including chrysopa spp. and peyerimhoffina gracilis.the enantiomerically pure diastereoisomers (1r,4s,4ar,7s,7ar)- (1) and (1r,4r,4ar,7s,7ar)-dihydronepetalactol (2) were synthesized diastereoselectively from a renewable resource, (4as,7s,7ar)-nepetalactone (3), isolated as the main constituent of the essential oil of the catmint plant nepeta cataria. the stereochemistry of the compounds was determined by nmr spectroscopy and x-ray crystallography, and the compounds were identified, respectively, as neomatatabiol and isoneomatatabiol, natural pro ...200212035931
anti-inflammation activity of actinidia polygama.the fruit of actinidia polygama (ap) has long been used as a folk medicine in korea for treating pain, rheumatic arthritis and inflammation. the present investigation was carried out to determine the in vivo and in vitro anti-inflammatory activity of ap using several animal models of inflammation. the 70% ethanol extract of the fruit of ap significantly inhibited acetic acid-induced, vascular permeability in a dose dependent manner (23%, 38%, and 41% inhibition at doses of 200 mg/kg, 500 mg/kg a ...200314723341
the antioxidative activity of traditional japanese herbs.the objective of this research was to examine the radical scavenging activity of traditional japanese herbs. samples used in the experiments were gennoshoko (geranium nepalense var. thunbergii), yomogi (artemisia vulgaris var.indica), senburi (swertia japonica), iwa-tobacco (conandron ramondioides), sarunokoshikake (elfvingia applanata), kanzo (glycyrrhiza uralensis fisch) and matatabi (actinidia polygama). the water-soluble components of the herbs were extracted in boiling water, and the volati ...200415630212
antimutagenicity of japanese traditional herbs, gennoshoko, yomogi, senburi and iwa-tobacco.the multistage induction theory is generally regarded as the mechanism of carcinogenesis. in order to prevent the initiation stage of carcinogenesis, it is meaningful to discover the functional components of edible plants. the objective of this research was to test the antimutagenicity of the functional components of several typical traditional herbs used in japan. the traditional herbs, gennoshoko (geranium nepalense var. thunbergii), yomogi (artemisia vulgaris var. indica), senburi (swertia ja ...200415630266
in vivo and in vitro anti-inflammatory activities of alpha-linolenic acid isolated from actinidia polygama fruits.the fruit of actinidia polygama (ap) has long been used as a folk medicine in korea for the treatment of pain, rheumatoid arthritis and inflammation. in the present study, bioassay-guided fractionation of ap led to the separation and identification of a polyunsaturated fatty acid, alpha-linolenic acid (ala), which was found to show anti-inflammatory activity. the anti-inflammatory effects of ala, using acetic acid or carrageenan-induced inflammation models, were investi gated in mice or rats, re ...200717679548
specific detection of potentially allergenic kiwifruit in foods using polymerase chain reaction.kiwifruit (actinidia deliciosa and actinidia chinensis) is allergenic to sensitive patients, and, under japanese regulations, it is one of the food items that are recommended to be declared on food labeling as much as possible. to develop pcr-based methods for the detection of trace amounts of kiwifruit in foods, two primer pairs targeting the its-1 region of the actinidia spp. were designed using pcr simulation software. on the basis of the known distribution of a major kiwifruit allergen (acti ...200717288438
[spectral analysis of maorenshen (actinidia valvata) and its confusable materials].this article reports the spectral analysis of maorenshen (actinidia valvata) and its confusable materials actinidia chinennsis and actinidia polygama by fluorescence test, ultraviolet spectrophotometry and fluorescence spectrophotometry. strong green or blue fluorescence was observed at uv 254 nm in aqueous solutions of actinidia chinesis and actinidia polygama, and was barely seen in that of maorenshen. there were also obvious differences among the ultraviolet spectra and fluorescence spectra o ...200312940006
stereochemistry of megastigmane glucosides from glochidion zeylanicum and alangium premnifolium.from glochidion zeylanicum, two megastigmane glucosides, 3- and 9-o-beta-d-glucopyranosides of (3s,5r,6r,7e,9s)-megastigman-7-ene-3,5,6,9-tetrol (1 and 2, respectively), were isolated. their structures were different from those of kiwiionoside (3) and actinidioionoside (4), isolated from actinidia chinensis and actinidia polygama, respectively, in the stereochemistry at the 9-positions. alangionosides e (5) and o (6), isolated from the leaves of alangium premnifolium, are also megastigmane gluco ...200312620329
responsiveness of cats (felidae) to silver vine (actinidia polygama), tatarian honeysuckle (lonicera tatarica), valerian (valeriana officinalis) and catnip (nepeta cataria).olfactory stimulation is an often overlooked method of environmental enrichment for cats in captivity. the best known example of olfactory enrichment is the use of catnip, a plant that can cause an apparently euphoric reaction in domestic cats and most of the pantherinae. it has long been known that some domestic cats and most tigers do not respond to catnip. although many anecdotes exist of other plants with similar effects, data are lacking about the number of cats that respond to these plants ...201728302120
a new diacetylated flavonol triglycoside from the aerial parts of actinidia polygama.phytochemical investigation of a methanolic extract of aerial parts actinidia polygama miq. led to the isolation of one new diacetylated flavonol triglycoside, kaempferol 3-o-[α-l-rhamnopyranosyl(1→3)-(4-o-acetyl)-o-α-l-rhamnopyranosyl(1→6)-(2-oacetyl)-o-β-d-galactopyranoside] (1) along with 12 known compounds (2-13). the chemical structures were determined using their spectroscopic data including 1d and 2d nmr. to the best of our knowledge, this is the first time that compounds 2, 4, 6, 7, 8, 9 ...201728114836
pharmacophagy in green lacewings (neuroptera: chrysopidae: chrysopa spp.)?green lacewings (neuroptera: chrysopidae) are voracious predators of aphids and other small, soft-bodied insects and mites. earlier, we identified (1r,2s,5r,8r)-iridodial from wild males of the goldeneyed lacewing, chrysopa oculata say, which is released from thousands of microscopic dermal glands on the abdominal sterna. iridodial-baited traps attract c. oculata and other chrysopa spp. males into traps, while females come to the vicinity of, but do not usually enter traps. despite their healthy ...201626819841
anti‑obesity effects of actinidia polygama extract in mice with high‑fat diet‑induced obesity.actinidia polygama has been used as a herbal folk medicine for treating pain, gout, rheumatoid arthritis and inflammation. in the present study, the anti‑obesity properties of actinidia polygama extract (ape) were investigated in mice with high‑fat diet‑induced obesity. ape treatment of high‑fat diet (hfd)‑fed obese mice significantly reduced body weight, adipose tissue mass and serum triglyceride and leptin levels relative to the hfd‑fed mice. food intake did not differ between the hfd and hfd+ ...201323255063
inhibitory effects of actinidiamide from actinidia polygama on allergy and inflammation.actinidia polygama max. was subjected to supercritical fluid extraction (sfe), and the resulting ethanol extract of marc (sfem) was subjected to sequential fractionation with various solvents. each extract and fraction was assayed for anti-inflammatory effect. the ethyl acetate fraction (etoac) contained the highest level (70.8% inhibition) of anti-inflammatory activity. in order to identify the active constituents, the etoac fraction was further fractionated by silica gel and ods column chromat ...201222313761
anti-inflammatory effect of alpha-linolenic acid and its mode of action through the inhibition of nitric oxide production and inducible nitric oxide synthase gene expression via nf-kappab and mitogen-activated protein kinase pathways.alpha-linolenic acid (ala) isolated from actinidia polygama fruits exhibits potent anti-inflammatory activity with an unknown mechanism. to elucidate the molecular mechanisms of ala on pharmacological and biochemical actions in inflammation, we examined the effect of ala on lipopolysaccharide (lps)-induced nitric oxide (no) production in the murine macrophages cell line, raw 264.7. we found that ala has a strong inhibitory effect on the production of no. ala also inhibited inducible nitric oxide ...200717542608
inhibitory effects of actinidia polygama extract and cyclosporine a on ova-induced eosinophilia and bronchial hyperresponsiveness in a murine model of asthma.actinidia polygama is one of the well known herb used in oriental medicine for treatment of anti-inflammatory and many allergic diseases. anti-asthmatic effects of a. polygama in the development of ova-induced eosinophilia and hyperresponsiveness in murine model of asthma have not been fully investigated in vivo. cyclosporine a (csa) has been shown to inhibit single allergen-induced allergic inflammation such as eosinophilic and lymphocytic infiltration and mrna expression for interleukin (il)-4 ...200616504935
differentiation-inducing effects of small fruit juices on hl-60 leukemic cells.epidemiological studies indicate that high intakes of fruits and vegetables are associated with a reduced risk of cancer, and several plant-derived drugs have been developed in medical oncology. since only a small part of the flora has been tested for any kind of bioactivity, we chose small fruits as sources of differentiation-inducing activity against hl-60 leukemic cells. we have prepared juices from various small fruits that grow mainly in the northern part of japan. screening of 43 samples i ...200010956088
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