| an epidemiologic and serologic study of arboviruses in lake rudolf basin. | an epidemiologic and serologic study of arboviruses was done in 1972 in the basin of lake rudolf. the main object of this study was to demarcate the southern limit of the yellow fever epidemic which occurred from 1959 to 1962 in southern sudan and ethiopia. other purposes were to contribute to the inventory of arboviruses and their distribution in this region. the ethnic groups were studied: the nyangatom and the dassanetch in ethiopia and the turkana in northern kenya. the results of tests on s ... | 1975 | 242102 |
| phylogeny of the genus flavivirus. | we undertook a comprehensive phylogenetic study to establish the genetic relationship among the viruses of the genus flavivirus and to compare the classification based on molecular phylogeny with the existing serologic method. by using a combination of quantitative definitions (bootstrap support level and the pairwise nucleotide sequence identity), the viruses could be classified into clusters, clades, and species. our phylogenetic study revealed for the first time that from the putative ancesto ... | 1998 | 9420202 |
| an agent related to uganda s virus from man and mosquitoes in south africa. | | 1959 | 13832180 |
| genetic relationships and evolution of genotypes of yellow fever virus and other members of the yellow fever virus group within the flavivirus genus based on the 3' noncoding region. | genetic relationships among flaviviruses within the yellow fever (yf) virus genetic group were investigated by comparing nucleotide sequences of the 3' noncoding region (3'ncr). size heterogeneity was observed between members and even among strains of the same viral species. size variation between yf strains was due to duplications and/or deletions of repeated nucleotide sequence elements (ryf). west african genotypes had three copies of the ryf (ryf1, ryf2, and ryf3); the angola and the east an ... | 2004 | 15331698 |
| bats: important reservoir hosts of emerging viruses. | bats (order chiroptera, suborders megachiroptera ["flying foxes"] and microchiroptera) are abundant, diverse, and geographically widespread. these mammals provide us with resources, but their importance is minimized and many of their populations and species are at risk, even threatened or endangered. some of their characteristics (food choices, colonial or solitary nature, population structure, ability to fly, seasonal migration and daily movement patterns, torpor and hibernation, life span, roo ... | 2006 | 16847084 |
| a short treatment of cells with the lanthanide ions la3+, ce3+, pr3+ or nd3+ changes the cellular chemistry into a state in which rna replication of flaviviruses is specifically blocked without interference with host-cell multiplication. | alpha- and flaviviruses contain class ii fusion proteins, which form ion-permeable pores in the target membrane during virus entry. the pores generated during entry of the alphavirus semliki forest virus have been shown previously to be blocked by lanthanide ions. here, analyses of the influence of rare earth ions on the entry of the flaviviruses west nile virus and uganda s virus revealed an unexpected effect of lanthanide ions. the results showed that a 30 s treatment of cells with an appropri ... | 2007 | 17947525 |
| structure and functionality in flavivirus ns-proteins: perspectives for drug design. | flaviviridae are small enveloped viruses hosting a positive-sense single-stranded rna genome. besides yellow fever virus, a landmark case in the history of virology, members of the flavivirus genus, such as west nile virus and dengue virus, are increasingly gaining attention due to their re-emergence and incidence in different areas of the world. additional environmental and demographic considerations suggest that novel or known flaviviruses will continue to emerge in the future. nevertheless, u ... | 2010 | 19945487 |
| molecular phylogeny of edge hill virus supports its position in the yellow fever virus group and identifies a new genetic variant. | edge hill virus (ehv) is a mosquito-borne flavivirus isolated throughout australia during mosquito surveillance programs. while not posing an immediate threat to the human population, ehv is a taxonomically interesting flavivirus since it remains the only member of the yellow fever virus (yfv) sub-group to be detected within australia. here we present both an antigenic and genetic investigation of collected isolates, and confirm taxonomic classification of the virus within the yfv-group. isolate ... | 2010 | 20938485 |
| probable non-vector-borne transmission of zika virus, colorado, usa. | clinical and serologic evidence indicate that 2 american scientists contracted zika virus infections while working in senegal in 2008. one of the scientists transmitted this arbovirus to his wife after his return home. direct contact is implicated as the transmission route, most likely as a sexually transmitted infection. | 2011 | 21529401 |
| Tembusu virus in ducks, china. | In China in 2010, a disease outbreak in egg-laying ducks was associated with a flavivirus. The virus was isolated and partially sequenced. The isolate exhibited 87%-91% identity with strains of Tembusu virus, a mosquito-borne flavivirus of the Ntaya virus group. These findings demonstrate emergence of Tembusu virus in ducks. | 2011 | 22000358 |
| proceedings of the african field epidemiology network (afenet) scientific conference 17-22 november 2013 addis ababa, ethiopia: plenaries and oral presentations. | biennially, trainees and graduates of field epidemiology and laboratory training programs (feltps) are presented with a platform to share investigations and projects undertaken during their two-year training in applied epidemiology. the african field epidemiology network (afenet) scientific conference, is a perfect opportunity for public health professionals from various sectors and organizations to come together to discuss issues that impact on public health in africa. this year's conference wa ... | 2015 | 26491534 |
| an updated checklist of mosquito species (diptera: culicidae) from madagascar. | an updated checklist of 235 mosquito species from madagascar is presented. the number of species has increased considerably compared to previous checklists, particularly the last published in 2003 (178 species). this annotated checklist provides concise information on endemism, taxonomic position, developmental stages, larval habitats, distribution, behavior, and vector-borne diseases potentially transmitted. the 235 species belong to 14 genera: aedeomyia (3 species), aedes (35 species), anophel ... | 2016 | 27101839 |
| seroepidemiology of selected arboviruses in febrile patients visiting selected health facilities in the lake/river basin areas of lake baringo, lake naivasha, and tana river, kenya. | arboviruses cause emerging and re-emerging infections affecting humans and animals. they are spread primarily by blood-sucking insects such as mosquitoes, ticks, midges, and sandflies. changes in climate, ecology, demographic, land-use patterns, and increasing global travel have been linked to an upsurge in arboviral disease. outbreaks occur periodically followed by persistent low-level circulation. | 0 | 25700043 |
| development of one-step quantitative reverse transcription pcr for the rapid detection of flaviviruses. | the genus flavivirus includes several pathogenic agents that cause severe illness in humans. re-emergence of west nile virus in europe and continuous spread of certain flaviviruses such as dengue, yellow fever and japanese encephalitis viruses represent a global danger to public health. therefore, a rapid and accurate molecular method is required for diagnostics and epidemiological surveillance of flaviviruses. | 2013 | 23410000 |
| ecuador paraiso escondido virus, a new flavivirus isolated from new world sand flies in ecuador, is the first representative of a novel clade in the genus flavivirus. | a new flavivirus, ecuador paraiso escondido virus (epev), named after the village where it was discovered, was isolated from sand flies (psathyromyia abonnenci, formerly lutzomyia abonnenci) that are unique to the new world. this represents the first sand fly-borne flavivirus identified in the new world. epev exhibited a typical flavivirus genome organization. nevertheless, the maximum pairwise amino acid sequence identity with currently recognized flaviviruses was 52.8%. phylogenetic analysis o ... | 2015 | 26355096 |
| characterization of a novel insect-specific flavivirus from brazil: potential for inhibition of infection of arthropod cells with medically important flaviviruses. | in the past decade, there has been an upsurge in the number of newly described insect-specific flaviviruses isolated pan-globally. we recently described the isolation of a novel flavivirus (tentatively designated 'nhumirim virus'; nhuv) that represents an example of a unique subset of apparently insect-specific viruses that phylogenetically affiliate with dual-host mosquito-borne flaviviruses despite appearing to be limited to replication in mosquito cells. we characterized the in vitro growth p ... | 2014 | 25146007 |
| experimental therapies for yellow fever. | a number of viruses in the family flaviviridae are the focus of efforts to develop effective antiviral therapies. success has been achieved with inhibitors for the treatment of hepatitis c, and there is interest in clinical trials of drugs against dengue fever. antiviral therapies have also been evaluated in patients with japanese encephalitis and west nile encephalitis. however, no treatment has been developed against the prototype flavivirus, yellow fever virus (yfv). despite the availability ... | 2012 | 23237991 |
| flavidb: a data mining system for knowledge discovery in flaviviruses with direct applications in immunology and vaccinology. | the flavivirus genus is unusually large, comprising more than 70 species, of which more than half are known human pathogens. it includes a set of clinically relevant infectious agents such as dengue, west nile, yellow fever, and japanese encephalitis viruses. although these pathogens have been studied extensively, safe and efficient vaccines lack for the majority of the flaviviruses. | 0 | 25544857 |
| observations on longevity and egg production in aedes (stegomyia) aegypti linn. mosquitoes infected with uganda s virus. | | 1962 | 14013820 |
| transmission of uganda s virus by aedes (steogmyia) aegypti linn. | | 1958 | 13581138 |
| uganda s virus; a hitherto unrecorded virus isolated from mosquitoes in uganda. i. isolation and pathogenicity. | | 1952 | 13005679 |