| [bacterial, viral and parasitological study of a population of chaerophon pumila bats in anjiro, madagascar]. | this bacterial, viral and parasitical study of the insect eater bats chaerophon pumila allowed to isolate, from stools of 88 of them, 115 bacterial strains to enterobacteriaceae family: some of them were identified as very atypical, rare or potentially pathogenic for man. from salivary glands, brain and blood, 13 viral strains were also isolated: 8 of them were less identified as dakar-bat virus. any parasite was observed. | 1989 | 2517389 |
| efficacy of rabies vaccines against duvenhage virus isolated from european house bats (eptesicus serotinus), classic rabies and rabies-related viruses. | isolates of rabies from separate enzootics can be distinguished by their reactions with panels of monoclonal antibodies (mabs) directed to different sites on the nucleocapsid and glycoproteins of the virus. estimates of antigenic relatedness can be made by comparing similarities among groups. in this manner it can be shown that while classic strains of rabies react with most of the mabs, the rabies related lyssaviruses (mokola, lagos and duvenhage) react with only a few of the mabs and isolates ... | 1988 | 3245296 |
| pathogenesis of rabies virus from a danish bat (eptesicus serotinus): neuronal changes suggestive of spongiosis. | rabies virus strains isolated from a european bat (eptesicus serotinus) in denmark (dbv), a north american big brown bat (eptesicus fuscus) in new york state (ny-bat), and a human in south africa (duvenhage strain (duv-1) were studied by using a panel of monoclonal antibodies and by inoculating mice, cats, and dogs. the ten danish virus isolates from the same bat species reacted identically with a panel of monoclonal antibodies. immunofluorescence, monoclonal antibody, and histopathologic studie ... | 1988 | 3369944 |
| kaposi's sarcoma and its management in aids patients. recommendations from a scandinavian study group. | ks is the most frequent malignancy in homo/bisexual male aids patients, affecting more than 30% of these patients. ks may present itself as a few innocent cutaneous lesions or may show progression resulting in severe morbidity and mortality. approximately half of the patients may develop severe progressive disease. the prognosis of patients with progressive disease is poor, with a median survival of less than 6 months. there is no cure for aids-related ks, but several therapies are available for ... | 1997 | 9112290 |
| bats: important reservoir hosts of emerging viruses. | bats (order chiroptera, suborders megachiroptera ["flying foxes"] and microchiroptera) are abundant, diverse, and geographically widespread. these mammals provide us with resources, but their importance is minimized and many of their populations and species are at risk, even threatened or endangered. some of their characteristics (food choices, colonial or solitary nature, population structure, ability to fly, seasonal migration and daily movement patterns, torpor and hibernation, life span, roo ... | 2006 | 16847084 |
| structure and functionality in flavivirus ns-proteins: perspectives for drug design. | flaviviridae are small enveloped viruses hosting a positive-sense single-stranded rna genome. besides yellow fever virus, a landmark case in the history of virology, members of the flavivirus genus, such as west nile virus and dengue virus, are increasingly gaining attention due to their re-emergence and incidence in different areas of the world. additional environmental and demographic considerations suggest that novel or known flaviviruses will continue to emerge in the future. nevertheless, u ... | 2010 | 19945487 |
| hemagglutinin displayed baculovirus protects against highly pathogenic influenza. | baculovirus (bv) replicating in insect cells can express a foreign gene product as part of its genome. the influenza hemagglutinin (ha) can be expressed from bv and displayed on the surface of baculovirus (ha-dbv). in this study we first generated six recombinant baculoviruses that expressed chimeric has with segments of the bv glycoprotein (gp64). the signal peptide (sp) and cytoplasmic tail (ct) domains of gp64 can enhance the display of ha from a/pr8/34 on bv surface, while the transmembrane ... | 2010 | 20727393 |
| Tembusu virus in ducks, china. | In China in 2010, a disease outbreak in egg-laying ducks was associated with a flavivirus. The virus was isolated and partially sequenced. The isolate exhibited 87%-91% identity with strains of Tembusu virus, a mosquito-borne flavivirus of the Ntaya virus group. These findings demonstrate emergence of Tembusu virus in ducks. | 2011 | 22000358 |
| laboratory surveillance of rabies in humans, domestic animals, and bats in madagascar from 2005 to 2010. | background. rabies virus (rabv) has circulated in madagascar at least since the 19th century. objectives. to assess the circulation of lyssavirus in the island from 2005 to 2010. materials and methods. animal (including bats) and human samples were tested for rabv and other lyssavirus using antigen, ribonucleic acid (rna), and antibodies detection and virus isolation. results. half of the 437 domestic or tame wild terrestrial mammal brains tested were found rabv antigen positive, including 54% o ... | 2011 | 21991442 |
| development of one-step quantitative reverse transcription pcr for the rapid detection of flaviviruses. | the genus flavivirus includes several pathogenic agents that cause severe illness in humans. re-emergence of west nile virus in europe and continuous spread of certain flaviviruses such as dengue, yellow fever and japanese encephalitis viruses represent a global danger to public health. therefore, a rapid and accurate molecular method is required for diagnostics and epidemiological surveillance of flaviviruses. | 2013 | 23410000 |
| flavidb: a data mining system for knowledge discovery in flaviviruses with direct applications in immunology and vaccinology. | the flavivirus genus is unusually large, comprising more than 70 species, of which more than half are known human pathogens. it includes a set of clinically relevant infectious agents such as dengue, west nile, yellow fever, and japanese encephalitis viruses. although these pathogens have been studied extensively, safe and efficient vaccines lack for the majority of the flaviviruses. | 0 | 25544857 |
| detection of entebbe bat virus after 54 years. | entebbe bat virus (entv; flaviviridae: flavivirus), closely related to yellow fever virus, was first isolated from a little free-tailed bat (chaerephon pumilus) in uganda in 1957, but was not detected after that initial isolation. in 2011, we isolated entv from a little free-tailed bat captured from the attic of a house near where it had originally been found. infectious virus was recovered from the spleen and lung, and the viral rna was sequenced and compared with that of the original isolate. ... | 2015 | 26101270 |
| bat distribution size or shape as determinant of viral richness in african bats. | the rising incidence of emerging infectious diseases (eid) is mostly linked to biodiversity loss, changes in habitat use and increasing habitat fragmentation. bats are linked to a growing number of eid but few studies have explored the factors of viral richness in bats. these may have implications for role of bats as potential reservoirs. we investigated the determinants of viral richness in 15 species of african bats (8 pteropodidae and 7 microchiroptera) in central and west africa for which we ... | 2014 | 24959855 |
| a review of flaviviruses that have no known arthropod vector. | most viruses in the genus flavivirus are horizontally transmitted between hematophagous arthropods and vertebrate hosts, but some are maintained in arthropod- or vertebrate-restricted transmission cycles. flaviviruses maintained by vertebrate-only transmission are commonly referred to as no known vector (nkv) flaviviruses. fourteen species and two subtypes of nkv flaviviruses are recognized by the international committee on taxonomy of viruses (ictv), and tamana bat virus potentially belongs to ... | 2017 | 28635667 |