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azaphilones and p-terphenyls from the mangrove endophytic fungus penicillium chermesinum (zh4-e2) isolated from the south china sea.eight secondary metabolites, including three new azaphilones (chermesinones a-c, 1-3), three new p-terphenyls (6'-o-desmethylterphenyllin, 4; 3-hydroxy-6'-o-desmethylterphenyllin, 5; 3''-deoxy-6'-o-desmethylcandidusin b, 7), and two known p-terphenyls (6, 8), were isolated from the culture of the mangrove endophytic fungus penicillium chermesinum (zh4-e2). their structures were established by spectroscopic analysis. the absolute configuration of 1 was determined by x-ray crystallography. terphen ...201121510637
microbial transformations of 3-methoxyflavone by strains of aspergillus niger.microbial transformation of 3-methoxyflavone into 3'-hydroxyflavon-3-yloxymethyl myristate was presented. six filamentous fungi were used as biocatalysts: a wild strain of aspergillus niger kb, its four uv mutants (a. niger mb, sbp, sbj, 13/5) and the strain of penicillium chermesinum 113. the highest yields were observed for the strains of a. niger kb and a. niger sbp (69.8% and 63.1%, respectively).201425033671
microbial transformations of 6- and 7-methoxyflavones in aspergillus niger and penicillium chermesinum cultures.a detailed study of the biotransformation of 6- and 7-methoxyflavones by four fungal strains (aspergillus niger strains mb, kb, and sbp; penicillium chermesinum 113) was carried out. products of demethylation and also demethylation combined with hydroxylation at c-4' were identified. the biotransformation products were stronger antioxidants than the substrates.201223016281
production and chemical characterization of pigments in filamentous fungi.production of pigments by filamentous fungi is gaining interest owing to their use as food colourants, in cosmetics and textiles, and because of the important biological activities of these compounds. in this context, the objectives of this study were to select pigment-producing fungi, identify these fungi based on internal transcribed spacer sequences, evaluate the growth and pigment production of the selected strains on four different media, and characterize the major coloured metabolites in t ...201626341482
chermesins a-d: meroterpenoids with a drimane-type spirosesquiterpene skeleton from the marine algal-derived endophytic fungus penicillium chermesinum en-480.chermesins a-d (1-4), four new spiromeroterpenoids containing a drimane-type sesquiterpene skeleton, were isolated and identified from the culture extract of penicillium chermesinum en-480, an endophytic fungus obtained from the inner tissue of the marine red alga pterocladiella tenuis. the structures of these new spiromeroterpenoids were elucidated based on detailed spectroscopic analyses, and their absolute configurations were confirmed by single-crystal x-ray diffraction experiments and by ec ...201626990653
distribution and antimicrobial potential of endophytic fungi associated with ethnomedicinal plant melastoma malabathricum l.distributions of endophytic fungi associated with ethnomedicinal plant melastoma malabathricum l. was studied and 91 isolates belonging to 18 genera were recovered. the isolates were distributed to sordariomycetes (62.63%), dothideomycetes (19.78%), eurotiomycetes (7.69%), zygomycetes (4.19%), agaricomycetes (1.09%), and mycelia sterilia (4.39%). based on colony morphology and examination of spores, the isolates were classified into 18 taxa, of which colletotrichum, phomopsis and phoma were domi ...201627097442
microbial transformations of 7-hydroxyflavanone.microbial transformations of racemic 7-hydroxyflavanone using strains of genus aspergillus (a. niger kb, a. niger 13/5, a. ochraceus 456) and the species penicillium chermesinum 113 were studied. the products of o-methylation, o-methylation along with hydroxylation at c-3' and c-4', reduction of the carbonyl group, reduction of the carbonyl group along with hydroxylation at c-5, and dehydrogenation of c-2 and c-3 were obtained. most of the products (with the exception of the o-methylation one) h ...201222654578
microbial transformations of 7-methoxyflavanone.microbial transformations of racemic 7-methoxyflavanone using strains of the genus aspergillus (a. niger kb, a. ochraceus 456) and the strain penicillium chermesinum 113 were described. the strain a. niger kb catalysed carbonyl group reduction, leading to (±)-2,4-cis-7-methoxyflavan-4-ol. biotransformation with the help of a. ochraceus 456 gave two products: (+)-2,4-trans-7-methoxyflavan-4-ol and 4'-hydroxy-7-methoxyflavone. transformation by means of p. chermesinum 113 resulted in a dihydrochal ...201223519254
two new inhibitors of phospholipase a2 produced by penicillium chermesinum. taxonomy, fermentation, isolation, structure determination and biological properties.plastatin and the known fungal metabolite, luteosporin, have been isolated from fermentations of penicillium chermesinum as inhibitors of porcine pancreatic phospholipase a2 (pla2). structure 1 for plastatin was deduced from its spectroscopic properties. plastatin and luteosporin inhibited pancreatic pla2 competitively with ki values of 0.89 microm and 12.8 microm, respectively. pla2 preparations from naja naja and crotalus adamanteus were not significantly inhibited by plastatin and luteosporin ...19853839502
costaclavine from penicillium chermesinum. 19645850492
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