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control of exocellular proteases in dermatophytes and especially trichophyton rubrum.the production of proteases was investigated during growth of dermatophytic fungi with special emphasis on trichophyton rubrum. exogenous glucose suppressed elastase production in all dermatophytes examined. the production of protease active guinea pig hair in keratin-salts broth by microsporum gypseum. trichophyton mentagrophytes and t. rubrum was also suppressed by glucose. various carbohydrates added to keratin-salts broth curtailed protease production by t. rubrum as did individual amino aci ...197994467
control of exocellular proteases in dermatophytes and especially trichophyton rubrum.the production of proteases was investigated during growth of dermatophytic fungi with special emphasis on trichophyton rubrum. exogenous glucose suppressed elastase production in all dermatophytes examined. the production of protease active guinea pig hair in keratin-salts broth by microsporum gypseum. trichophyton mentagrophytes and t. rubrum was also suppressed by glucose. various carbohydrates added to keratin-salts broth curtailed protease production by t. rubrum as did individual amino aci ...197994467
human infections with microsporum gypseum in denmark.ninety cases of microsporum gypseum infection in denmark during the period 1933-1977 are reviewed. the sex ratio, age distribution, and anatomical sites are started. a case of onychomycosis in a 1-year-old child is reported, and the cases of m. gypseum onychomycosis in the literature are reviewed.1978152115
human infections with microsporum gypseum in denmark.ninety cases of microsporum gypseum infection in denmark during the period 1933-1977 are reviewed. the sex ratio, age distribution, and anatomical sites are started. a case of onychomycosis in a 1-year-old child is reported, and the cases of m. gypseum onychomycosis in the literature are reviewed.1978152115
culture medium alkalinization by dermatophyes. (influence of time and temperature of incubation).95 dermatophyte strains (12 of trichophyton mentagrophytes, 12 of t. tonsurans, 11 of t. rubrum, 12 of t. megninii, 12 of t. violaceum, 2 of t. schoenleinii, 1 of t. soudanense, 12 of m. canis, 8 of microsporum gypseum, 1 of m. ferrugineum and 12 of epidermphoyton floccosum). 1 of aspergillus niger, 1 of a. ochraceus, 1 of paecilomyces sp., 1 of penicillium sp. and 1 of candida albicans were grown in sabouraud liquid medium for the study of ph variation over 6 weeks at room temperature and after ...1975238130
culture medium alkalinization by dermatophyes. (influence of time and temperature of incubation).95 dermatophyte strains (12 of trichophyton mentagrophytes, 12 of t. tonsurans, 11 of t. rubrum, 12 of t. megninii, 12 of t. violaceum, 2 of t. schoenleinii, 1 of t. soudanense, 12 of m. canis, 8 of microsporum gypseum, 1 of m. ferrugineum and 12 of epidermphoyton floccosum). 1 of aspergillus niger, 1 of a. ochraceus, 1 of paecilomyces sp., 1 of penicillium sp. and 1 of candida albicans were grown in sabouraud liquid medium for the study of ph variation over 6 weeks at room temperature and after ...1975238130
[isolation, purification and biochemical properties of keratinase elaborated from microsporum gypseum (author's transl)]. 1977301579
[isolation, purification and biochemical properties of keratinase elaborated from microsporum gypseum (author's transl)]. 1977301579
in vitro survival of human pathogenic fungi in hawaiian beach sand.in vitro studies utilizing 4 pathogenic fungi, trichosporon cutaneum, candida albicans, microsporum gypseum and trichophyton mentagrophytes, all known from hawaiian beaches, indicate that they survive in the fluctuating beach habitat where they can serve as potential sources of infection for significant periods of time. survival was measured by testing the viability of propagules at intervals for 6 months. all species survived 6 months under 1 or more experimental conditions. survival patterns s ...1979375438
in vitro survival of human pathogenic fungi in hawaiian beach sand.in vitro studies utilizing 4 pathogenic fungi, trichosporon cutaneum, candida albicans, microsporum gypseum and trichophyton mentagrophytes, all known from hawaiian beaches, indicate that they survive in the fluctuating beach habitat where they can serve as potential sources of infection for significant periods of time. survival was measured by testing the viability of propagules at intervals for 6 months. all species survived 6 months under 1 or more experimental conditions. survival patterns s ...1979375438
n-demethylation of nicotine and reduction of nicotine-1'-n-oxide by microsporum gypseum.several microorganisms were examined for their abilities to convert s-nicotine into nornicotine. five microorganisms including microsporum gypseum (atcc 11395) produced nornicotine and three unknown metabolites. m. gypseum efficiently reduced nicotine-1'-n-oxide to nicotine, but no nornicotine was obtained when the n-oxide was used as substrate.1979543700
n-demethylation of nicotine and reduction of nicotine-1'-n-oxide by microsporum gypseum.several microorganisms were examined for their abilities to convert s-nicotine into nornicotine. five microorganisms including microsporum gypseum (atcc 11395) produced nornicotine and three unknown metabolites. m. gypseum efficiently reduced nicotine-1'-n-oxide to nicotine, but no nornicotine was obtained when the n-oxide was used as substrate.1979543700
pyrolysis gas-liquid chromatography applied to a study of variation in arthroderma tuberculatum.replicates of whole colonies of four species of closely related dermatophytes were analyzed by pyrolysis gas-liquid chromatography (pglc). the four species included fifteen strains of arthroderma tuberculatum, and two strains each of a. benhamiae, nannizzia gypsea and n. incurvata. individual peaks on different pyrograms were identified as homologous with the aid of internal markers by the superimposition of pyrograms. the peak height data extracted from the pyrograms of the fungal samples were ...1978567743
lipid composition of microsporum gypseum.the lipid composition of microsporum gypseum has been studied. the lipids amounted to 10.1% and phospholipids to 1.1% of the mycelial dry weight. phosphatidyl choline, phosphatidyl serine and phosphatidyl ethanolamine were the major components, while lysophosphatidyl choline, and phosphatidyl inositol were present in smaller quantities. neutral lipids consisted of monoglycerides, diglycerides, triglycerides, free and esterified cholesterol.1978639933
lipid composition of microsporum gypseum.the lipid composition of microsporum gypseum has been studied. the lipids amounted to 10.1% and phospholipids to 1.1% of the mycelial dry weight. phosphatidyl choline, phosphatidyl serine and phosphatidyl ethanolamine were the major components, while lysophosphatidyl choline, and phosphatidyl inositol were present in smaller quantities. neutral lipids consisted of monoglycerides, diglycerides, triglycerides, free and esterified cholesterol.1978639933
survey of keratinophilic fungi in alpine marmot (marmota marmota) burrow soil and in adjoining soils.soil samples from 127 marmot (marmota marmota) burrows were examined for keratinophilic fungi along with 48 soil samples from adjoining areas. the occurrence of keratinophilic fungi (especially microsporum gypseum) was significantly higher in burrow soil. a review of the literature and our results support the hypothesis that the "animalization" (i.e. the enrichment of soil with hairs, crusts and other organic matters) of the environment may create conditions suitable for the growth of keratinoph ...1978635727
survey of keratinophilic fungi in alpine marmot (marmota marmota) burrow soil and in adjoining soils.soil samples from 127 marmot (marmota marmota) burrows were examined for keratinophilic fungi along with 48 soil samples from adjoining areas. the occurrence of keratinophilic fungi (especially microsporum gypseum) was significantly higher in burrow soil. a review of the literature and our results support the hypothesis that the "animalization" (i.e. the enrichment of soil with hairs, crusts and other organic matters) of the environment may create conditions suitable for the growth of keratinoph ...1978635727
resistance of selected saprobic and zoopathogenic fungi to cycloheximide.spore germination was used as an assay to measure the sensitivities of selected fungi (achlya bisexualis, cladosporium sp., trichophyton mentagrophytes and microsporum gypseum) to cyclohexamide and to determine their abilities to adapt to the drug. two patterns of response were noted. the saprobes, a. bisexualis and cladosporium sp., demonstrated acquired resistance. spores from hyphae previously exposed to cycloheximide either germinated in the presence of concentrations of the drug that comple ...1978632807
resistance of selected saprobic and zoopathogenic fungi to cycloheximide.spore germination was used as an assay to measure the sensitivities of selected fungi (achlya bisexualis, cladosporium sp., trichophyton mentagrophytes and microsporum gypseum) to cyclohexamide and to determine their abilities to adapt to the drug. two patterns of response were noted. the saprobes, a. bisexualis and cladosporium sp., demonstrated acquired resistance. spores from hyphae previously exposed to cycloheximide either germinated in the presence of concentrations of the drug that comple ...1978632807
naphthyridinomycin, a new broad-spectrum antibiotic.a new antibiotic, naphthyridinomycin, was isolated in crystalline form from the culture filtrate of streptomyces lusitanus ay b-1026. the antibiotic is active against a large number of both gram-positive and gram-negative bacteria, and inactive against candida albicans, trichophyton granulosum and microsporum gypseum. the antibiotic is toxic in mice.1975807549
naphthyridinomycin, a new broad-spectrum antibiotic.a new antibiotic, naphthyridinomycin, was isolated in crystalline form from the culture filtrate of streptomyces lusitanus ay b-1026. the antibiotic is active against a large number of both gram-positive and gram-negative bacteria, and inactive against candida albicans, trichophyton granulosum and microsporum gypseum. the antibiotic is toxic in mice.1975807549
protoplasts of microsporum gypseum conidia. 1979542206
protoplasts of microsporum gypseum conidia. 1979542206
[research of keratinophiles in the soil and their effects on human cutaneous pathology in the lyons area].between 1967 and 1977, the systematic research of keratinophiles of the ground in a radius of 30--50 km around lyon, has shown the ubiquitarian predominance of microsporum nanum, which is probably the most ancient occupant of the ground. the most intensive areas of human and animal occupation in the rhodanian tract show the predominance of microsporum gypseum, which is scarcely found in man. sporadic localizations, tightly limites, bound to cirulcation axes and international gathering, let us de ...1979488487
[research of keratinophiles in the soil and their effects on human cutaneous pathology in the lyons area].between 1967 and 1977, the systematic research of keratinophiles of the ground in a radius of 30--50 km around lyon, has shown the ubiquitarian predominance of microsporum nanum, which is probably the most ancient occupant of the ground. the most intensive areas of human and animal occupation in the rhodanian tract show the predominance of microsporum gypseum, which is scarcely found in man. sporadic localizations, tightly limites, bound to cirulcation axes and international gathering, let us de ...1979488487
[microsporum gypseum: endothrix parasitism with medium or large spores in hair of children].five cases of tinea corporis in children by microsporum gypseum are presented. in four of them an endothrix type of parasitism with arthrospores 4 to 8 microns in diameter was observed. in the other case ectothrix and endothrix types of parasitism were seen in different hairs. endothrix infection of hairs by species of the genus microsporum has not been clearly demonstrated until the present. three isolates were identified as nannazzia gypsea of the "+" mating type.1979441901
[microsporum gypseum: endothrix parasitism with medium or large spores in hair of children].five cases of tinea corporis in children by microsporum gypseum are presented. in four of them an endothrix type of parasitism with arthrospores 4 to 8 microns in diameter was observed. in the other case ectothrix and endothrix types of parasitism were seen in different hairs. endothrix infection of hairs by species of the genus microsporum has not been clearly demonstrated until the present. three isolates were identified as nannazzia gypsea of the "+" mating type.1979441901
effects of age on fresh weight, proteins, peroxidases, and other enzymes of the +, -, and crossed gymnothecial cultures of nannizzia gypsea.cultures of the + (uamh 1485) and - (uamh 1486) mating types of nannizzia gypsea and their crosses (1485 x 1486) were analyzed, after 1, 2, 3, and 4 weeks growth, for fresh weight, proteins, peroxidases, esterases, acid- and alkaline-phosphatases. the + type produced slightly more growth at all periods (90, 131, 131, and 129 mg/plate) than the - mating type (90, 123, 121, and 108 mg/plate). the growth of the crosses was much less (30, 88, 83, and 94 mg/plate). total soluble proteins per gram fre ...1977865597
[in vitro effectiveness of salicylic, benzoic and boric acid and diiodine thymol solutions on various strains of dermatophytes].in order to study the in vitro behavior of the drug used according to our formula cultures of trichophyton mentagrophytes. trichophyton rubrum, trichophyton verrucosum, trichophyton tonsurans, microsporum canis, microsporum gallinae, microsporum audouinii, microsporum gypseum and epidermophyton floccosum were prepared in order to prove its efficacy. it was found no growth in cultures to which the drug was added in different concentrations thus proving its efficacy as a fungistatic element. the i ...1979395583
[in vitro effectiveness of salicylic, benzoic and boric acid and diiodine thymol solutions on various strains of dermatophytes].in order to study the in vitro behavior of the drug used according to our formula cultures of trichophyton mentagrophytes. trichophyton rubrum, trichophyton verrucosum, trichophyton tonsurans, microsporum canis, microsporum gallinae, microsporum audouinii, microsporum gypseum and epidermophyton floccosum were prepared in order to prove its efficacy. it was found no growth in cultures to which the drug was added in different concentrations thus proving its efficacy as a fungistatic element. the i ...1979395583
in vitro survival of human pathogenic fungi in seawater.the survival of propagules from 4 pathogenic fungi, trichophyton mentagrophytes, trichosporon cutaneum, candida albicans, and microsporum gypseum was studied in seawater subjected to different temperature (20--35 degrees c) and salinity (6--50%) levels in diurnal rhythm of 12 h cycles. survival was measured by viability of propagules over a period of 52 weeks. all fungi, except t. cutaneum at 35 degrees c survived the experimental conditions for 52 weeks. temperature was the most influential fac ...1979375437
in vitro survival of human pathogenic fungi in seawater.the survival of propagules from 4 pathogenic fungi, trichophyton mentagrophytes, trichosporon cutaneum, candida albicans, and microsporum gypseum was studied in seawater subjected to different temperature (20--35 degrees c) and salinity (6--50%) levels in diurnal rhythm of 12 h cycles. survival was measured by viability of propagules over a period of 52 weeks. all fungi, except t. cutaneum at 35 degrees c survived the experimental conditions for 52 weeks. temperature was the most influential fac ...1979375437
kerion-like tinea capitis and barbae caused by microsporum gypseum in israel.four cases of hair invasion by microsporum gypseum are reported. in three the scalp was involved and in one, the beard. all presented a kerion type of invasion. in 3 cases hair penetration was of the ectothrix type, while in one case the kerion of the scalp resembled the type of invasion seen in t. schonleini infection. none of the invaded hairs showed fluorescence in wood's light. the soil was the source of infection in 3 patients, the fungus having been isolated from soil samples collected in ...1976967226
kerion-like tinea capitis and barbae caused by microsporum gypseum in israel.four cases of hair invasion by microsporum gypseum are reported. in three the scalp was involved and in one, the beard. all presented a kerion type of invasion. in 3 cases hair penetration was of the ectothrix type, while in one case the kerion of the scalp resembled the type of invasion seen in t. schonleini infection. none of the invaded hairs showed fluorescence in wood's light. the soil was the source of infection in 3 patients, the fungus having been isolated from soil samples collected in ...1976967226
microsporum gypseum infection in three mexican prairie dogs. 1979256357
microsporum gypseum infection in three mexican prairie dogs. 1979256357
[on the frequency of dermatophytes of so called microsporum gypseum complex in garden soils and on the experimental pathogenicity of these agents (author's transl)]. 1979161866
[on the frequency of dermatophytes of so called microsporum gypseum complex in garden soils and on the experimental pathogenicity of these agents (author's transl)]. 1979161866
distribution of nuclei in macroconidia of microsporum gypseum.the distribution of nuclei in macroconidia was investigated in 20 strains of the dermatophyte microsporum gypseum by fluorescence microscopy. the macroconidia were characterized by the right-left and the central-marginal symmetry indices. in 18 strains the significant majority of the nuclei were situated in the basal part of the macroconidium, the remaining 2 strains showed a more or less uniform distribution of nuclei. all strains had higher numbers of nuclei in the central part of the macrocon ...197770393
distribution of nuclei in macroconidia of microsporum gypseum.the distribution of nuclei in macroconidia was investigated in 20 strains of the dermatophyte microsporum gypseum by fluorescence microscopy. the macroconidia were characterized by the right-left and the central-marginal symmetry indices. in 18 strains the significant majority of the nuclei were situated in the basal part of the macroconidium, the remaining 2 strains showed a more or less uniform distribution of nuclei. all strains had higher numbers of nuclei in the central part of the macrocon ...197770393
the distribution of geophilic dermatophytes in kenyan soils.two hundred and eighty one soil samples from different provinces of kenya were examined for dermatophytes by the hair baiting technique. dermatophytes were recovered from 84 samples. microsporum gypseum constituted 75.8% of the total isolates while keratinomyces ajelloi and m. cookei formed 21% and 3.2%, respectively. the distribution of the dermatophytes was influences by soil ph, being more prevalent in acidic than in alkaline soils.197829226
the distribution of geophilic dermatophytes in kenyan soils.two hundred and eighty one soil samples from different provinces of kenya were examined for dermatophytes by the hair baiting technique. dermatophytes were recovered from 84 samples. microsporum gypseum constituted 75.8% of the total isolates while keratinomyces ajelloi and m. cookei formed 21% and 3.2%, respectively. the distribution of the dermatophytes was influences by soil ph, being more prevalent in acidic than in alkaline soils.197829226
in vitro and in vivo photosensitized inactivation of dermatophyte fungi by heterotricyclic dyes.the ability of three heterotricyclic dyes to photosensitize dermatophyte fungi was studied with trichophyton mentagrophytes and microsporum gypseum. in vitro studies showed that methylene blue, neutral red, and proflavine were capable of killing these fungi when used in conjunction with broad-spectrum light. proflavine, however, killed both fungi most rapidly and was used for further studies. fungal killing by proflavine plus light was dependent on dye concentration, ph, light wavelength, and li ...1978669788
studies on dermatophytosis in dogs. iii. an experimental study on some factors for establishment of infection with microsporum gypseum of soil origin. 1978642221
rapamycin (ay-22,989), a new antifungal antibiotic. i. taxonomy of the producing streptomycete and isolation of the active principle.a streptomycete was isolated from an easter island soil sample and found to inhibit candida albicans, microsporum gypseum and trichophyton granulosum. the antibiotic-producing microorganism was characterized and identified as streptomyces hygroscopicus. the antifungal principle was extracted with organic solvent from the mycelium, isolated in crystalline form and named rapamycin. rapamycin is mainly active against candida albicans; minimum inhibitory concentration against ten strains ranged from ...19751102508
rapamycin (ay-22,989), a new antifungal antibiotic. i. taxonomy of the producing streptomycete and isolation of the active principle.a streptomycete was isolated from an easter island soil sample and found to inhibit candida albicans, microsporum gypseum and trichophyton granulosum. the antibiotic-producing microorganism was characterized and identified as streptomyces hygroscopicus. the antifungal principle was extracted with organic solvent from the mycelium, isolated in crystalline form and named rapamycin. rapamycin is mainly active against candida albicans; minimum inhibitory concentration against ten strains ranged from ...19751102508
studies on dermatophytosis in dogs. iii. an experimental study on some factors for establishment of infection with microsporum gypseum of soil origin. 1978642221
in vitro and in vivo photosensitized inactivation of dermatophyte fungi by heterotricyclic dyes.the ability of three heterotricyclic dyes to photosensitize dermatophyte fungi was studied with trichophyton mentagrophytes and microsporum gypseum. in vitro studies showed that methylene blue, neutral red, and proflavine were capable of killing these fungi when used in conjunction with broad-spectrum light. proflavine, however, killed both fungi most rapidly and was used for further studies. fungal killing by proflavine plus light was dependent on dye concentration, ph, light wavelength, and li ...1978669788
isolation of ethyl p-methoxycinnamate, the major antifungal principle of curcumba zedoaria.an antifungal principle of the dried rhizomes of curcuma zedoaria was extracted with hot ethanol. by successive chromatography on neutral alumina and silica gel, three antibiotic compounds a, b, and c, all active against trichophyton rubrum, aspergillus niger and saccharomyces cerevisiae, were obtained in chemically pure form. by uv, ir, pmr and ms analysis, the structure of the most abundant one of these compounds (c, 69.8%; h, 6,8%; and 0.23.4%) was assigned as ethyl p-methoxycinnamate (epmc). ...1976785141
isolation of ethyl p-methoxycinnamate, the major antifungal principle of curcumba zedoaria.an antifungal principle of the dried rhizomes of curcuma zedoaria was extracted with hot ethanol. by successive chromatography on neutral alumina and silica gel, three antibiotic compounds a, b, and c, all active against trichophyton rubrum, aspergillus niger and saccharomyces cerevisiae, were obtained in chemically pure form. by uv, ir, pmr and ms analysis, the structure of the most abundant one of these compounds (c, 69.8%; h, 6,8%; and 0.23.4%) was assigned as ethyl p-methoxycinnamate (epmc). ...1976785141
occurrence of histoplasma capsulatum darling, 1906 in israel, with a review of the current status of histoplasmosis in the middle east.the isolation of histoplasma capsulatum from a bat cave in the galilee region of israel is reported along with the discovery of a bat (myotis myotis) infected by h. capsulatum. soils collected in avian and chiropteran habitats throughout israel also yielded the following fungi of medical interest: arthroderma quadrifidum, a. tuberculatum, candida parapsilosis, chrysosporium indicum, c. keratinophilum, c. tropicum, cryptococcus neoformans, ctenomyces serratus, microsporum gypseum, and petriellidi ...1977842775
occurrence of histoplasma capsulatum darling, 1906 in israel, with a review of the current status of histoplasmosis in the middle east.the isolation of histoplasma capsulatum from a bat cave in the galilee region of israel is reported along with the discovery of a bat (myotis myotis) infected by h. capsulatum. soils collected in avian and chiropteran habitats throughout israel also yielded the following fungi of medical interest: arthroderma quadrifidum, a. tuberculatum, candida parapsilosis, chrysosporium indicum, c. keratinophilum, c. tropicum, cryptococcus neoformans, ctenomyces serratus, microsporum gypseum, and petriellidi ...1977842775
an uncommon case of tinea pedis caused by microsporum gypseum. 1977853215
an uncommon case of tinea pedis caused by microsporum gypseum. 1977853215
[epidemic outbreak of tinea corporis due to microsporum gypseum].a small epidemic of tinea corporis due to m. gypseum is reported. there were 13 children affected, ages 1-15 years. these children belonged to 6 neighbouring families and all used a common "playground", an empty lot located nearby. cultures were positive for m. gypseum in the 13 children and the agent was also isolated from 2 soils collected in the playing-ground. soil isolates were classified as n. gypsea. clinically, the lesions were circinated and had active borders, they were preferentially ...1977865596
[epidemic outbreak of tinea corporis due to microsporum gypseum].a small epidemic of tinea corporis due to m. gypseum is reported. there were 13 children affected, ages 1-15 years. these children belonged to 6 neighbouring families and all used a common "playground", an empty lot located nearby. cultures were positive for m. gypseum in the 13 children and the agent was also isolated from 2 soils collected in the playing-ground. soil isolates were classified as n. gypsea. clinically, the lesions were circinated and had active borders, they were preferentially ...1977865596
use of immunofluorescence staining in kerion.we describe two cases of kerion caused by trichophyton rebrum and microsporum gypseum. in the histological sections, a pas stain revealed a small number of hypha-like rods and spore-like round bodies in the dermis of patient 1. except for some clusters of pas-positive materials, no definite fungal elements were observed in the dermis of patient 1, whereas a considerable number of hyphae were demonstrated within a hair shaft. immunofluorescence staining, using fluorescein-labeled t mentagrophytes ...19751096827
ultrastructure of ascosporogenesis in nannizzia gypsea.ascosporogenesis in nannizzia gypsea was studied by electron microscopy. development of ascospores began with the formation of an ascus vesicle composed of two paired unit membranes. myelin figures consisting of coiled or concentric membranes were regularly connected with the growing ascus vesicle. both the ascus vesicle and the myelin figures possessed an electron-dense line between paired membranes, and both were stained by the periodic acid-silver methenamine technique. invagination of the as ...19751126919
saprophytic occurrence of trichophyton mentagrophytes and microsporum gypseum in the coats of healthy laboratory animals. (preliminary report).a group of 199 healthy laboratory animals, comprising 63 guinea pigs; 58 white mice. 47 rats and 31 rabbits, was sampled for the presence of pathogenic dermatophytes. t. mentagrophytes, var. granulare, was isolated in 10% (5-guinea pigs, 6 mice, 6 rats and 2 rabbits) and m. gypseum was found in 7 animals (3 guinea pigs, 3 mice and one rat). no ringworm lesions were observed in the respective animals. this is the first report on such findings in israel.19751143311
saprophytic occurrence of trichophyton mentagrophytes and microsporum gypseum in the coats of healthy laboratory animals. (preliminary report).a group of 199 healthy laboratory animals, comprising 63 guinea pigs; 58 white mice. 47 rats and 31 rabbits, was sampled for the presence of pathogenic dermatophytes. t. mentagrophytes, var. granulare, was isolated in 10% (5-guinea pigs, 6 mice, 6 rats and 2 rabbits) and m. gypseum was found in 7 animals (3 guinea pigs, 3 mice and one rat). no ringworm lesions were observed in the respective animals. this is the first report on such findings in israel.19751143311
formation of sulphate, sulphite and s-sulphocysteine by the fungus microsporum gypseum during growth on cystine.the dermatophyte microsporum gypseum was cultivated in media containing 0.5% cystine in suspension, and 0.05% peptone or 1% glucose and 0.05% peptone. during growth on cystine the excess sulphur was oxidized and excreted into the medium not only in the form of sulphate but also in the form of sulphite. sulphite was produced especially during first phases of growth, where its quantity was higher than that of sulphate and its maximum concentration exceeded 1 mg/ml. s-sulphocysteine, detected chrom ...19751176037
formation of sulphate, sulphite and s-sulphocysteine by the fungus microsporum gypseum during growth on cystine.the dermatophyte microsporum gypseum was cultivated in media containing 0.5% cystine in suspension, and 0.05% peptone or 1% glucose and 0.05% peptone. during growth on cystine the excess sulphur was oxidized and excreted into the medium not only in the form of sulphate but also in the form of sulphite. sulphite was produced especially during first phases of growth, where its quantity was higher than that of sulphate and its maximum concentration exceeded 1 mg/ml. s-sulphocysteine, detected chrom ...19751176037
the nuclear dna-dependent ribonucleic acid polymerases of the dermatophytic fungus microsporum gypseum.the dna-dependent rna polymerases of the dermatophytic fungus microsporum gypseum were partially characterized. nuclear extracts prepared from vegetative mycelia were fractionated by deae-sephadex chromatography into three enzyme species which resembled in most of their characteristics those of other eukaryotic organisms.19761260524
evaluation of keratinolytic potential of some fungal isolates from gelatin factory campus.during hair degradation, majority of organic sulphur was oxidized to inorganic sulphate and thiosulphate by four fungal isolates (cylindrocarpon lichenicola, graphium cuneiferum, microsporum gypseum, and m. fulvum) from gelatin factory soil. inorganic thiosulphate, an unusual metabolite, was regularly detected in the culture filtrates of all fungi, although in less amounts. maximum quantity (44 micrograms/ml) was released by g. cuneiferum on 50th day of incubation. all four fungi showed signific ...19921381699
evaluation of keratinolytic potential of some fungal isolates from gelatin factory campus.during hair degradation, majority of organic sulphur was oxidized to inorganic sulphate and thiosulphate by four fungal isolates (cylindrocarpon lichenicola, graphium cuneiferum, microsporum gypseum, and m. fulvum) from gelatin factory soil. inorganic thiosulphate, an unusual metabolite, was regularly detected in the culture filtrates of all fungi, although in less amounts. maximum quantity (44 micrograms/ml) was released by g. cuneiferum on 50th day of incubation. all four fungi showed signific ...19921381699
the nuclear dna-dependent ribonucleic acid polymerases of the dermatophytic fungus microsporum gypseum.the dna-dependent rna polymerases of the dermatophytic fungus microsporum gypseum were partially characterized. nuclear extracts prepared from vegetative mycelia were fractionated by deae-sephadex chromatography into three enzyme species which resembled in most of their characteristics those of other eukaryotic organisms.19761260524
temperature induced dimorphism in microsporum gypseum.the biochemical mutant of microsporum gypseum requiring adenine shows characteristic dimorphism dependent upon temperature. at 37 degrees c it produces faviform aconidial colonies with spherical swollen cells similar to thin-walled chlamydospores. at 26 degrees c it yields the usual mycelium with conidia. conversion of the faviform and mycelial forms is controlled by temperature and reversible.1977888596
microsporum gypseum complex in man and animals.twenty-eight strains of the microsporum gypseum complex isolated from humans and animals were studied. the perfect form was found for 25 of the isolates. nannizzia incurvata was the species most frequently involved in human pathology, while nannizzia gypsea was most frequently found on animal lesions. nannizzia fulva was rarely involved pathologically and nannizzia corniculata was not isolated during this study. it is surprising to note that this species was not found even though most of our str ...19921432489
microsporum gypseum complex in man and animals.twenty-eight strains of the microsporum gypseum complex isolated from humans and animals were studied. the perfect form was found for 25 of the isolates. nannizzia incurvata was the species most frequently involved in human pathology, while nannizzia gypsea was most frequently found on animal lesions. nannizzia fulva was rarely involved pathologically and nannizzia corniculata was not isolated during this study. it is surprising to note that this species was not found even though most of our str ...19921432489
temperature induced dimorphism in microsporum gypseum.the biochemical mutant of microsporum gypseum requiring adenine shows characteristic dimorphism dependent upon temperature. at 37 degrees c it produces faviform aconidial colonies with spherical swollen cells similar to thin-walled chlamydospores. at 26 degrees c it yields the usual mycelium with conidia. conversion of the faviform and mycelial forms is controlled by temperature and reversible.1977888596
sulphitolysis in keratinolysi. biochemical proof.the presence of s-sulphocysteine in filtrates of the dermatophyte keratinomyces ajelloi growing on human hair in a culture medium buffered by ph 7-4 by phosphates was demonstrated by means of ion exchange chromatography techniques. s-sulphocysteine being destroyed during acidic hydrolysis was identified after enzymic hyrolysis of dialyzed and lyophilized filtrates. this result indicates that sulphitolysis occurs during kerationlysis performed by k. ajelloi. as thiosulphuric esters were shown pre ...1976959943
sulphitolysis in keratinolysi. biochemical proof.the presence of s-sulphocysteine in filtrates of the dermatophyte keratinomyces ajelloi growing on human hair in a culture medium buffered by ph 7-4 by phosphates was demonstrated by means of ion exchange chromatography techniques. s-sulphocysteine being destroyed during acidic hydrolysis was identified after enzymic hyrolysis of dialyzed and lyophilized filtrates. this result indicates that sulphitolysis occurs during kerationlysis performed by k. ajelloi. as thiosulphuric esters were shown pre ...1976959943
keratin decomposition by dermatophytes. ii. presence of s-sulfocysteine and cysteic acid in soluble decomposition products.the dermatophyte microsporum gypseum was grown on human hair in a mineral medium. filtrates of cultures of various age were chromatographed on sephadex gels and further characterized by chemical analysis and thin-layer chromatography. the products of keratin decomposition were separated into two fractions. the first fraction formed 10 to 20% of the bulk and contained proteins low in sulfur content. the second, very wide fraction contained oligopeptides and polypeptides with molecular weights fro ...1976969572
keratin decomposition by dermatophytes. ii. presence of s-sulfocysteine and cysteic acid in soluble decomposition products.the dermatophyte microsporum gypseum was grown on human hair in a mineral medium. filtrates of cultures of various age were chromatographed on sephadex gels and further characterized by chemical analysis and thin-layer chromatography. the products of keratin decomposition were separated into two fractions. the first fraction formed 10 to 20% of the bulk and contained proteins low in sulfur content. the second, very wide fraction contained oligopeptides and polypeptides with molecular weights fro ...1976969572
[scanning electron microscopic study of the human hair, affected by the dermatophyte microsporum gypseum (bodin) guiart and griogorakis in vitro]. 1976980003
[scanning electron microscopic study of the human hair, affected by the dermatophyte microsporum gypseum (bodin) guiart and griogorakis in vitro]. 1976980003
microsporum gypseum infection in a dromedary camel. 19751041647
microsporum gypseum infection in a dromedary camel. 19751041647
isolation of keratinophilic fungi from soil in pavia, italy.the examination of keratinophilic fungi in 125 soil samples collected in pavia, italy revealed the following organism: microsporum gypseum 23, m. vanbreuseghemii 4, arthroderma uncinatum 4, ctenomyces serratus 5, chrysosporium tropicum 5, unidentified gymnoascacean 1. arthroderma uncinatum, m. gypseum, m. vanbreuseghemii were isolated from a city park and cultivated soils; c. tropicum, ct. serratus and an unidentified gymnoascacean were found only in soils from natural woods. the distribution of ...19751091998
isolation of keratinophilic fungi from soil in pavia, italy.the examination of keratinophilic fungi in 125 soil samples collected in pavia, italy revealed the following organism: microsporum gypseum 23, m. vanbreuseghemii 4, arthroderma uncinatum 4, ctenomyces serratus 5, chrysosporium tropicum 5, unidentified gymnoascacean 1. arthroderma uncinatum, m. gypseum, m. vanbreuseghemii were isolated from a city park and cultivated soils; c. tropicum, ct. serratus and an unidentified gymnoascacean were found only in soils from natural woods. the distribution of ...19751091998
influence of aminophylline on the lipids in microsporum gypseum.the effect of aminophylline on the lipid synthesis of microsporum gypseum has been examined. a decreased incorporation of [14c]acetate into lipids was observed when the cells were incubated for 1 h with aminophylline which was reflected in all the individual lipid fractions. however, cells grown with aminophylline in the growth medium exhibited increased levels of total phospholipids, which was probably due to a rise in intracellular camp as these cells exhibited 4-fold increased levels of camp. ...19911846758
biochemical and morphological effects of polyamine biosynthesis inhibitors on trichophyton and microsporum.the minimum inhibitory concentrations (mics) of three known irreversible inhibitors of polyamine synthesis, alpha-difluoromethylornithine (dfmo) and monofluoromethyldehydroornithine methylester (mfmome), inhibitors of ornithine decarboxylase (odc) and alpha-difluoromethylarginine (dfma), an inhibitor of arginine decarboxylase (adc), were determined for 10 species of dermatophytic fungi. trichophyton species were generally more sensitive to these inhibitors than microsporum species. both genera p ...19911880681
biochemical and morphological effects of polyamine biosynthesis inhibitors on trichophyton and microsporum.the minimum inhibitory concentrations (mics) of three known irreversible inhibitors of polyamine synthesis, alpha-difluoromethylornithine (dfmo) and monofluoromethyldehydroornithine methylester (mfmome), inhibitors of ornithine decarboxylase (odc) and alpha-difluoromethylarginine (dfma), an inhibitor of arginine decarboxylase (adc), were determined for 10 species of dermatophytic fungi. trichophyton species were generally more sensitive to these inhibitors than microsporum species. both genera p ...19911880681
sparse diversity of potential pathogenic soil micro-fungi in the ukraine.soil from steppe and garden reserves, and urban park and wharf regions in the ukraine, u.s.s.r., were studied for keratinophilic as well as for other predominant micro-fungal species. most of the fungi were nonpathogens, and potential skin infecting fungi were limited to microsporum gypseum and trichophyton ajelloi. species diversity identified population variation between collection sites.19912030648
sparse diversity of potential pathogenic soil micro-fungi in the ukraine.soil from steppe and garden reserves, and urban park and wharf regions in the ukraine, u.s.s.r., were studied for keratinophilic as well as for other predominant micro-fungal species. most of the fungi were nonpathogens, and potential skin infecting fungi were limited to microsporum gypseum and trichophyton ajelloi. species diversity identified population variation between collection sites.19912030648
fungal flora of the coat of pet cats.the fungal flora of the coat of 172 healthy pet cats was examined qualitatively. fungi were isolated from 136 (79%) of the 172 cats. fifteen genera were isolated; 13 are commonly regarded as saprophytes, and 2 (microsporum and trichophyton) are commonly regarded as pathogens. aspergillus, alternaria, penicillium, and cladosporium spp were the most frequently isolated saprophytes. dermatophytic fungi, including microsporum gypseum (n = 1), m vanbreuseghemii (n = 1), and trichophyton rubrum (n = 1 ...19912053732
fungal flora of the coat of pet cats.the fungal flora of the coat of 172 healthy pet cats was examined qualitatively. fungi were isolated from 136 (79%) of the 172 cats. fifteen genera were isolated; 13 are commonly regarded as saprophytes, and 2 (microsporum and trichophyton) are commonly regarded as pathogens. aspergillus, alternaria, penicillium, and cladosporium spp were the most frequently isolated saprophytes. dermatophytic fungi, including microsporum gypseum (n = 1), m vanbreuseghemii (n = 1), and trichophyton rubrum (n = 1 ...19912053732
plants used in guatemala for the treatment of dermatophytic infections. 1. screening for antimycotic activity of 44 plant extracts.skin infections are common diseases in developing countries, of which dermatophytoses are of particular concern in the tropics, especially in infants. through ethnobotanical surveys and literature review 100 plants were detected as being used in guatemala for the treatment of dermatophytoses. of these, 44 plants were screened for in vitro activity against the most common dermatophytes (epidermophyton floccosum, microsporum canis, microsporum gypseum, trichophyton mentagrophytes and trichophyton ...19912056755
plants used in guatemala for the treatment of dermatophytic infections. 1. screening for antimycotic activity of 44 plant extracts.skin infections are common diseases in developing countries, of which dermatophytoses are of particular concern in the tropics, especially in infants. through ethnobotanical surveys and literature review 100 plants were detected as being used in guatemala for the treatment of dermatophytoses. of these, 44 plants were screened for in vitro activity against the most common dermatophytes (epidermophyton floccosum, microsporum canis, microsporum gypseum, trichophyton mentagrophytes and trichophyton ...19912056755
use of immunofluorescence staining in kerion.we describe two cases of kerion caused by trichophyton rebrum and microsporum gypseum. in the histological sections, a pas stain revealed a small number of hypha-like rods and spore-like round bodies in the dermis of patient 1. except for some clusters of pas-positive materials, no definite fungal elements were observed in the dermis of patient 1, whereas a considerable number of hyphae were demonstrated within a hair shaft. immunofluorescence staining, using fluorescein-labeled t mentagrophytes ...19751096827
pattern of dermatophyte infection in singapore.dermatophyte infection is the fourth commonest skin disorder seen in the national skin centre in singapore. a prospective study was carried out from june 1990 to march 1991 to determine the epidemiology and pattern of dermatophyte infections seen in this centre. two hundred patients who had a clinical diagnosis of dermatophyte infection and confirmed by direct microscopy were included into the study. cultures for dermatophyte were done on sabouraud's dextrose agar with chloramphenicol and cycloh ...19921295417
pattern of dermatophyte infection in singapore.dermatophyte infection is the fourth commonest skin disorder seen in the national skin centre in singapore. a prospective study was carried out from june 1990 to march 1991 to determine the epidemiology and pattern of dermatophyte infections seen in this centre. two hundred patients who had a clinical diagnosis of dermatophyte infection and confirmed by direct microscopy were included into the study. cultures for dermatophyte were done on sabouraud's dextrose agar with chloramphenicol and cycloh ...19921295417
correlation between intracellular camp levels and phospholipids of microsporum gypseum.atropine, a modulator of camp has been used to examine the relationship between phospholipids and intracellular levels of camp in microsporum gypseum. a decreased phospholipid content was observed in atropine grown cells as a result of reduced levels of intracellular camp. this decline was caused by the inhibitory effect of atropine on adenylate cyclase. lowered phospholipid content was supported by decreased [14c]acetate incorporation as well as reduced activities of key enzymes of phospholipid ...19921311953
correlation between intracellular camp levels and phospholipids of microsporum gypseum.atropine, a modulator of camp has been used to examine the relationship between phospholipids and intracellular levels of camp in microsporum gypseum. a decreased phospholipid content was observed in atropine grown cells as a result of reduced levels of intracellular camp. this decline was caused by the inhibitory effect of atropine on adenylate cyclase. lowered phospholipid content was supported by decreased [14c]acetate incorporation as well as reduced activities of key enzymes of phospholipid ...19921311953
occurrence of keratinolytic fungi and related dermatophytes in soils in cairo, egypt.120 soil samples collected from various sites of cairo were processed for the isolation of keratinophilic fungi by "tokava" hair baiting technique. 22 species belonging to 6 genera were isolated viz.: chrysosporium tropicum, c. indicum, c. keratinophilum, c. queenslandicum, c. merdarium, c. anamorph of arthroderma curreyi, c. pannicola, c. lobatum, c. anamorph of renispora flavissima, c. pseudomerdarium, microascus mangini, malbranchea gypsea, ml. state of uncicarpus reesii, ml. state of coccidi ...19921380752
occurrence of keratinolytic fungi and related dermatophytes in soils in cairo, egypt.120 soil samples collected from various sites of cairo were processed for the isolation of keratinophilic fungi by "tokava" hair baiting technique. 22 species belonging to 6 genera were isolated viz.: chrysosporium tropicum, c. indicum, c. keratinophilum, c. queenslandicum, c. merdarium, c. anamorph of arthroderma curreyi, c. pannicola, c. lobatum, c. anamorph of renispora flavissima, c. pseudomerdarium, microascus mangini, malbranchea gypsea, ml. state of uncicarpus reesii, ml. state of coccidi ...19921380752
in vitro degradation of human hair by hendersonula toruloidea.the in vitro ability of 5 hendersonula toruloidea and 1 control microsporum gypseum strain to degrade human hair has been studied by analysis of culture medium and microscopy. h. toruloidea was able to utilize human hair as a source of nutrients but the extent varied according to the isolate and in all cases degradation was less marked than with m. gypseum.19751224288
in vitro degradation of human hair by hendersonula toruloidea.the in vitro ability of 5 hendersonula toruloidea and 1 control microsporum gypseum strain to degrade human hair has been studied by analysis of culture medium and microscopy. h. toruloidea was able to utilize human hair as a source of nutrients but the extent varied according to the isolate and in all cases degradation was less marked than with m. gypseum.19751224288
[antimicrobial activity of selected aqua-carboxyl-cupric complexes].the activity of compounds of different structural types of aqua-complexes of the composition cu(r-coo)2.nh2o-methoxybenzoatocupric complexes, r = 2-, 3- and 4-methoxyphenyl (n = 1, 1 and 3); aryloxyacetatocupric complexes, r = phenoxymethyl (n = 3), 2-, 3- and 4-chlorophenoxymethyl (n = 4, 2 and 2) and 1-naphthoxymethyl (n = 4), and furthermore isomeric furanecarboxylato-(r = 2- or 3-furyl, n = 3, or 1) and thiophencarboxylatocupric complexes (r = 2- or 3-thienyl, n = 1 and 1), was examined by t ...19921394479
[dermatomycoses observed at the dermatologic clinic, pavia university. 2) pathology of microsporum gypseum].microsporum gypseum infections are 0.4% of 4900 suspected dermatomycoses examined with direct microscopic exam and culture on lactrimel medium or d.t.m. this geophilic dermatophyte was isolated in 20 cases (1.5% of all dermatophytes). more frequently m. gypseum caused tinea corporis (13 cases: 65%) and rarely tinea capitis (2 cases: 10%), tinea faciei (2 cases), tinea manus (2 cases) and tinea cruris (1 case). both sexes are equally affected. direct microscopic exam was negative in 2 cases. this ...19902365400
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