Publications

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a physicochemical and pharmacological study of the newly synthesized complex of albendazole and the polysaccharide arabinogalactan from larch wood.inclusion complexes of albendazole (abz) with the polysaccharide arabinogalactan from larch wood larix sibirica and larix gmelinii were synthesized using a solid-state mechanochemical technology. we investigated physicochemical properties of the synthesized complexes in the solid state and in aqueous solutions as well as their anthelmintic activity against trichinella spiralis, hymenolepis nаna, fasciola hepatica, opisthorchis felineus, and mixed nematodoses of sheep. formation of the complexes ...201525981412
effects of tree species richness and composition on moose winter browsing damage and foraging selectivity: an experimental study.the optimal foraging theory, the nutrient balance hypothesis, and the plant association theories predict that foraging decisions and resulting tree damage by large mammalian browsers may be influenced by the species richness and species composition of forest stands. this may lead to either associational susceptibility (increased damage on a focal plant in a mixed stand) or associational resistance (reduced damage in a mixed stand). better understanding of the mechanisms and the relative importan ...201323363076
virus-inhibiting activity of dihydroquercetin, a flavonoid from larix sibirica, against coxsackievirus b4 in a model of viral pancreatitis.members of the family picornaviridae, in particular, enteroviruses, represent a serious threat to human health. they are responsible for numerous pathologies ranging from mild disease to fatal outcome. due to the limited number of safe and effective antivirals against enteroviruses, there is a need for search and development of novel drugs with various mechanisms of activity against enteroviruses-induced pathologies. we studied the effect of dihydroquercetin (dhq), a flavonoid from larch wood, o ...201626780775
[anticoagulant activity of arabinogalactane sulfate and cedar bark extract studied in vitro].we have studied in vitro the ability of the siberian cedar crust (scc) extract (pinus sibirica du tour) and arabinogalactan sulphate (ags) extracted from wood of siberiam pine-tree (larix sibirica ledeb.) to increase the human blood plasma coagulation time and also to inhibit the amydolytic activity of thrombin (aiia) and the coagulation factor xa (axa). a method has been developed by means of which scc increases the axa activity by a factor of 3.7 and the aiià activity by a factor of 2.5. the a ...200818819438
treeline advances along the urals mountain range - driven by improved winter conditions?high-altitude treelines are temperature-limited vegetation boundaries, but little quantitative evidence exists about the impact of climate change on treelines in untouched areas of russia. here, we estimated how forest-tundra ecotones have changed during the last century along the ural mountains. in the south, north, sub-polar, and polar urals, we compared 450 historical and recent photographs and determined the ages of 11,100 trees along 16 altitudinal gradients. in these four regions, boundari ...201424756980
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