| heartworm (dirofilaria immitis) disease and glomerulonephritis in a black-footed cat (felis nigripes). | a 6-yr-old, 1.36-kg, intact female black-footed cat (felis nigripes) was presented to the veterinary medical teaching hospital, university of florida, with a history of depression, lethargy, and anorexia. cardiac dysfunction and renal failure were diagnosed on the basis of antemortem and postmortem findings. at necropsy, heartworms (dirofilaria immitis), glomerulonephritis, and endometritis were present. the glomerulonephritis could have been immune mediated and may have been associated with the ... | 1998 | 9732037 |
| amplification of telomeric dna and the extent of karyotypic evolution. | the distribution of telomeric dna in the genomes of the antelope ground squirrel, ammospermophilus harrisii (family sciuridae; 2n = 32) and the african black-footed cat, felis nigripes (family felidae; 2n = 38) were compared by fluorescence in situ hybridization (fish) technique. these two mammalian species have the highest and the lowest amount of c-banded regions, respectively. fish preparations with the human telomeric dna probe showed that all c-banded segments in the a. harrisii chromosomes ... | 1998 | 9779588 |
| control of reproduction and sex related behaviour in exotic wild carnivores with the gnrh analogue deslorelin: preliminary observations. | the gnrh analogue deslorelin, in long-acting implants, was used in an attempt to temporarily control reproduction or aggression in wild carnivores in southern africa and the usa. in the southern african study, 6 mg deslorelin was administered to cheetahs (eight females, four males), one female leopard and wild dogs (six females, one male) housed in groups, and 12 mg deslorelin was administered to two lionesses. none of the animals became pregnant after deslorelin administration apart from one wi ... | 2001 | 11787162 |
| nuclear transfer in cats and its application. | nuclear transfer (nt) technology is typically used for generating identical individuals, but it is also a powerful resource for understanding the cellular and molecular aspects of nuclear reprogramming. most recently, the procedure has been used in humans for producing patient-specific embryonic stem cells. the successful application of nt in cats was demonstrated by the birth of domestic and non-domestic cloned kittens at a similar level of efficiency to that reported for other mammalian specie ... | 2006 | 16620927 |
| application of assisted reproduction for population management in felids: the potential and reality for conservation of small cats. | assisted reproductive technology (art), using the primary applied tools of ai, et, and sperm and embryo cryopreservation, has been promoted over the past decades for its potential to conserve endangered wildlife, including felids. however, if the goal is efficient, consistent production of viable offspring for population management, then the 'potential' of art has yet to become 'reality' for any non-domestic cat species. for the five small-sized felids (i.e., brazilian ocelot, fishing cat, palla ... | 2006 | 16650889 |
| sperm cryopreservation in endangered felids: developing linkage of in situ-ex situ populations. | many of the world's cat species face growing threats to their continued survival in nature. for some species, managed captive populations may provide a reservoir for future reintroduction or genetic augmentation. because most zoo populations are derived from small founder sizes and are subject to loss of genetic variation over time, periodic infusion of founder alleles is necessary to avoid the dire consequences of inbreeding. collection and freezing of semen from free-living nondomestic felids ... | 2007 | 17644981 |
| amyloidosis in black-footed cats (felis nigripes). | a high prevalence of systemic amyloidosis was documented in the black-footed cat (felis nigripes) based on a retrospective review of necropsy tissues (n = 38) submitted as part of ongoing disease surveillance. some degree of amyloid deposition was present in 33 of 38 (87%) of the examined cats, and amyloidosis was the most common cause of death (26/38, 68%). amyloid deposition was most severe in the renal medullary interstitium (30/33, 91%) and glomeruli (21/33, 63%). other common sites included ... | 2008 | 18487501 |
| fecal endocrine profiles and ejaculate traits in black-footed cats (felis nigripes) and sand cats (felis margarita). | information regarding the reproductive biology of black-footed cats (bfc) and sand cats (sc) is extremely limited. our objectives were to: (1) validate fecal hormone analysis (estrogens, e; progestagens, p; androgens, t) for noninvasive monitoring of gonadal activity; (2) characterize estrous cyclicity, ovulatory mechanisms, gestation, and seasonality; and (3) evaluate male reproductive activity via fecal androgen metabolites and ejaculate traits. in both species, the estrous cycle averaged 11-1 ... | 2010 | 19576217 |
| in vitro fertilization and sperm cryopreservation in the black-footed cat (felis nigripes) and sand cat (felis margarita). | studies of in vitro fertilization (ivf) and sperm cryopreservation have been conducted in several small cat species, but virtually no data exist for black-footed cats (felis nigripes) (bfcs) or sand cats (felis margarita) (scs). the objectives of this study were 1) to compare in vitro motility and acrosome status of fresh and cryopreserved (frozen in pellets on dry ice or in straws in liquid nitrogen vapor) bfc and sc spermatozoa cultured in feline-optimized culture medium (focm) or ham f-10, 2) ... | 2010 | 19906688 |
| evolutionary dynamics of endogenous feline leukemia virus proliferation among species of the domestic cat lineage. | endogenous feline leukemia viruses (enfelvs) occur in the germ lines of the domestic cat and related wild species (genus felis). we sequenced the long terminal repeats and part of the env region of enfelvs in domestic cats and five wild species. a total of 305 enfelv sequences were generated across 17 individuals, demonstrating considerable diversity within two major clades. distinct proliferations of enfelvs occurred before and after the black-footed cat diverged from the other species. diversi ... | 2010 | 20615520 |
| trichostatin a modified histone covalent pattern and enhanced expression of pluripotent genes in interspecies black-footed cat cloned embryos but did not improve in vitro and in vivo viability. | abstract the black-footed cat (bfc; felis nigripes), one of the smallest wild cats, is listed as threatened. interspecies somatic cell nuclear transfer (is-scnt) offers the possibility of preserving endangered species. development to term of interspecies bfc (is-bfc) cloned embryos has not been obtained, possibly due to abnormal epigenetic reprogramming. treatment of intraspecies cloned embryos with tsa improves nuclear reprogramming and in vitro and in vivo viability. in this study, we evaluate ... | 2011 | 21718106 |
| Carnivoran remains from the Malapa hominin site, South Africa. | Recent discoveries at the new hominin-bearing deposits of Malapa, South Africa, have yielded a rich faunal assemblage associated with the newly described hominin taxon Australopithecus sediba. Dating of this deposit using U-Pb and palaeomagnetic methods has provided an age of 1.977 Ma, being one of the most accurately dated, time constrained deposits in the Plio-Pleistocene of southern Africa. To date, 81 carnivoran specimens have been identified at this site including members of the families Ca ... | 2011 | 22073222 |
| herpesvirus and calicivirus infection in a black-footed cat (fels nigripes) family group following vaccination. | preventive healthcare recommendations for zoo felids include vaccination against primary viral diseases that affect domestic felids. although associated with a more-substantial immune response in their domestic counterparts, use of modified live virus vaccines (mlv) in nondomestic carnivores can result in vaccine-induced viral disease. this case report details a feline herpesvirus and calicivirus outbreak in two black-footed cat (felis nigripes) kittens and their dam following use of an mlv in t ... | 2015 | 25831588 |
| feline panleukopaenia virus in captive non-domestic felids in south africa. | an outbreak of feline panleukopaenia virus (fplv) infection was diagnosed by pathology, electron microscopy and polymerase chain reaction (pcr) in vaccinated captive-bred subadult cheetahs in south africa. subsequent to this disease outbreak, 12 cases of fplv diagnosed on histology were confirmed by pcr in captive african black-footed cat, caracal, cheetah, lion, ocelot and serval. phylogenetic analyses of the viral capsid protein gene on pcr-positive samples, vaccine and national center for bio ... | 2016 | 27380652 |
| parasites of domestic and wild animals in south africa. xlviii. ticks (acari: ixodidae) infesting domestic cats and wild felids in southern africa. | ticks collected from domestic cats (felis catus), cheetahs (acinonyx jubatus),caracals (caracal caracal), african wild cats (felis lybica), black-footed cats (felis nigripes), a serval (leptailurus serval), lions(panthera leo), and leopards (panthera pardus) were identified and counted. thirteen species of ixodid ticks and one argasid tick were identified from domestic cats and 17 species of ixodid ticks from wild felids. the domestic cats and wild felids harboured 11 ixodid species in common. t ... | 2010 | 23327159 |
| early-onset progressive retinal atrophy associated with an iqcb1 variant in african black-footed cats (felis nigripes). | african black-footed cats (felis nigripes) are endangered wild felids. one male and full-sibling female african black-footed cat developed vision deficits and mydriasis as early as 3 months of age. the diagnosis of early-onset progressive retinal atrophy (pra) was supported by reduced direct and consensual pupillary light reflexes, phenotypic presence of retinal degeneration, and a non-recordable electroretinogram with negligible amplitudes in both eyes. whole genome sequencing, conducted on two ... | 2017 | 28322220 |
| characterization and multilineage differentiation of domestic and black-footed cat mesenchymal stromal/stem cells from abdominal and subcutaneous adipose tissue. | transplantation of mesenchymal stem cells (mscs) isolated from bone marrow or adipose tissue is emerging as a promising tool for cell replacement therapy and regenerative medicine in domestic and endangered animal species. defining the differentiation capability of adipose-derived mesenchymal stromal/stem cells (amscs) collected from different depot sites of adipose tissue will be essential for developing strategies for cell replacement therapy. in the present study, we compared the biological c ... | 2015 | 26317245 |
| applying embryo cryopreservation technologies to the production of domestic and black-footed cats. | our objectives were (i) compare in vitro development of early cleavage stage domestic cat embryos after cryopreservation by minimal volume vitrification vs a standard slow, controlled-rate method, (ii) determine viability of vitrified domestic cat embryos by oviductal transfer into synchronous recipients and (iii) evaluate in vivo survival of black-footed cat (bfc, felis nigripes) embryos after intra- and inter-species transfer. in vitro-derived (ivm/ivf) cat embryos were used to evaluate in vit ... | 2012 | 23279481 |
| a molecular phylogeny of the felidae: immunological distance. | the phylogenetic distances between 34 of the 37 extant species of felidae were estimated using albumin immunological distances (aid). albumins from ten cat species were used to prepare antisera in rabbits. a consensus phylogeny was constructed from a matrix of reciprocal aid measurements using four distinct phylogenetic algorithms. a series of one-way measurements using the ten index antisera and those 24 species for which albumins were available (but antisera were not), permitted addition of th ... | 1985 | 28561961 |
| aspects of in vivo oocyte production, blastocyst development, and embryo transfer in the cat. | a brief overview of the progress made during the past approximately 40 years on the development of methods for in vitro production of cat embryos and intra- and interspecies embryo transfer is described. the presentation is focused primarily on research done over the past 30 years at the cincinnati zoo (1980-1995) and at the audubon nature institute, new orleans (1996-present) beginning with original studies on determining optimal doses of porcine fsh for ovarian stimulation and uterine embryo r ... | 2014 | 24274417 |
| scriptaid and 5-aza-2'deoxycytidine enhanced expression of pluripotent genes and in vitro developmental competence in interspecies black-footed cat cloned embryos. | somatic cell nuclear transfer offers the possibility of preserving endangered species including the black-footed cat, which is threatened with extinction. the effectiveness and efficiency of somatic cell nuclear transfer (scnt) depends on a variety of factors, but 'inappropriate epigenetic reprogramming of the transplanted nucleus is the primary cause of the developmental failure of cloned embryos. abnormal epigenetic events such as dna methylation and histone modifications during scnt perturb t ... | 2012 | 23279482 |
| characterization of mesenchymal stem cells derived from adipose tissue of a cougar (puma concolor). | adipose derived mesenchymal stem cells (amscs) have been isolated from domestic and wild cats. for wild cats, the isolation of amscs has been reported in the black-footed cats (felis nigripes) and guigna (leopardus guigna). stromal vascular fraction (svf) isolated from cougar adipose tissue have been used to restore elbow functionality in the cougar (puma concolor) but multipotent characteristics of these cells have not been described. the present study describes for the first time the isolation ... | 2020 | 32714450 |
| cross-species efficacy of a chemically-defined, soy lecithin-based cryomedium for semen banking in imperiled wild felids. | felid semen has historically been frozen using an egg yolk-based cryopreservation medium. however, the use of egg introduces several potential concerns, such as variability in composition, microbial contamination, and regulatory issues. in the present study, our aim was to compare a chemically-defined, soy-based medium (soy) to a commercial egg yolk-based medium (tey) for the cryopreservation of sperm in four imperiled small cat species. semen was collected from adult male cats (n = 6 black-foot ... | 2020 | 33130295 |
| novel pregnancy diagnosis and altrenogest supplementation lead to successful pregnancy in a black-footed cat (felis nigripes). | this is the first time fecal prostaglandin f2α metabolite (pgfm) analysis and altrenogest were used to determine and maintain a pregnancy in a zoo-housed black-footed cat (bfc; felis nigripes). the established pair had not produced offspring during the year since their arrival at birmingham zoo. fecal samples were collected daily and analyzed by enzyme immunoassay for progestagen, estrogen metabolite, and pgfm concentrations. after a 4-mo separation, the pair was reintroduced, and breeding was r ... | 2019 | 31260225 |
| corrigendum: early-onset progressive retinal atrophy associated with an iqcb1 variant in african black-footed cats (felis nigripes). | this corrects the article doi: 10.1038/srep43918. | 2018 | 29773894 |