| actin filaments in trabecular endothelial cells in eyes of the vervet monkey. (cercopithecus aethiops). | an electron microscopic study was performed on the trabecular meshwork of two monkeys (cercopithecus aethiops). specimens from one animal revealed numerous cytoplasmic filaments of 45-65 a thickness in endothelial cells both on the trabeculae in the wall of schlemm's canal after conventional glutaraldehyde and osmium fixation. using a histochemical technique it was shown in specimens from the other animal that these filaments consist of actin material. this evidence of intracellular actin filame ... | 1978 | 96655 |
| an antigen resembling hl-a7 on the leukocytes of vervet monkeys. | human leukocyte typing sera of known specificities were used to test the leukocyte antigens of vervet monkeys. the results suggest that these leukocytes contained an antigen resembling the hl-a7 antigen of human leukocytes. this is similar to a previous observation with leukocytes from baboons. these findings are consistent with the suggestion that the 4a/4b complex is the precursor substance from which the other specificities have evolved. | 1978 | 101671 |
| brain region differences and some characteristics of monoamine oxidase type a and b activities in the vervet monkey. | monoamine oxidase in the vervet monkey showed greater variations in activity in six brain regions when tyramine or phenylethylamine was used as the substrate (3.8- to 4.1-fold differences) than when serotonin was the substrate (1.8-fold differences). with phenylethylamine and tyramine as substrates, the highest mao specific activities were found in the hypothalamus and the lowest in the cerebellum and cortex. with serotonin as the substrate, the highest specific activities were in the mesencepha ... | 1979 | 109783 |
| the effect of oral pancreatic enzymes on the intestinal flora of protein-deficient vervet monkeys challenged with vibrio cholerae. | jejunal bacterial flora in 11 protein deficient vervet monkeys (cercopithecus aethiops) and four controls was studied. these were the same animals from an investigation previously reported in which it was shown that pancreatic extract modified the course of cholera infection in protein-deficient monkeys. the present study reports in addition that these animals the fluid in the upper jejunum contained significantly increased numbers of bacteria including enterobacteriaceae compared to its prediet ... | 1979 | 111538 |
| characterization of sa12 as a simian virus 40-related papovavirus of chacma baboons. | sa12 virus, originally isolated from an uninoculated south african vervet monkey kidney culture, was identified as a new member of the simian virus 40 (sv40)-polyoma subgroup of papovaviruses. the virus produced a cytopathic effect with nuclear enlargement in primary rhesus kidney cells. the virion had papovavirus morphology and a diameter of 44 to 45 nm. the dna of the virus was a circular, double-stranded, superhelical molecule with a mean length 101% that of sv40 dna and an estimated molecula ... | 1977 | 198375 |
| nonhuman primates: laboratory animals of choice for neurophysiologic studies of sleep. | a systematic study was made of several nonhuman primates to learn more about their relative usefulness for studies of sleep. species studied included the guinea baboon (papio papio), kenya or yellow baboon (p cynocephalus), olive baboon (p anubis), sacred baboon (p hamadryas), vervet monkey (cercopithecus aethiops), rhesus monkey (macaca mulatta), bonnet monkey (m radiata), crab-eating monkey (m fascicularis), patas monkey (erythrocebus patas), chimpanzee (pan troglodytes), mongoose lemur (lemur ... | 1977 | 201798 |
| antigenic relationships among several simian varicella-like viruses and varicella-zoster virus. | cross-neutralization and complement fixation tests demonstrated the immunological identity of the delta herpesvirus, the 592s virus, the liverpool vervet monkey virus, the herpesvirus of patas monkeys, and the medical lake macaque virus. these viruses were isolated from diverse outbreaks of varicella-like disease in simians and from various simian species. all of the simian viruses were shown to be related to human varicella-zoster (v-z) virus, as evidenced by the fact that immunization of monke ... | 1977 | 192676 |
| experimental infection of monkeys with viruses of the tick-borne encephalitis complex: degenerative cerebellar lesions following inapparent forms of the disease or recovery from clinical encephalitis. | rhesus, patas and vervet monkeys were infected i.c. or i.n. with three viruses of the tick-borne encephalitis complex (tbe) as follows: turkish tick-borne encephalitis virus (tte), louping-ill virus and central european tick-borne encephalitis virus (cete). the incidence of overt clinical signs of disease varied according to the virus that was used for the inoculations. tte proved to be more pathogenic for monkeys than the other two members of the complex, whilst cete was the least pathogenic. i ... | 1976 | 178337 |
| adenosine 3',5'-monophosphate analogue increases the outflow facility of the primate eye. | our previous studies showed that cyclic-amp increases the outflow facility of the eye of the rabbit. in this investigation, an analogue of cyclic-amp, the 8-methylthio derivative, perfused into the anterior chamber of the eye of the vervet monkey, increased outflow facility twofold. this observation supports the hypothesis that cyclic-amp mediates the action of adrenergic agents to reduce intraocular pressure in the primate eye. | 1975 | 169206 |
| a histological and scanning electron microscopy study of the muco-gingival junction in the vervet monkey. | | 1976 | 133224 |
| surface characteristics of cells from different layers of keratinized and non-keratinized oral epithelia. | portions of clinically healthy non-keratinized and keratinized oral epithelia were removed from adult vervet monkeys (cercopithecus aethiops). the epithelium was separated from the underlying lamina propria by trypsin digestion, following which the epithelial cells were separated from the various epithelial layers. these were examined with the light and scanning electron microscope. cells from non-keratinized epithelia have surface microplications while those from keratinized epithelia show m ... | 1975 | 124340 |
| long-term retention of a visually cued poison-based aversion in monkeys. | retention of a poison-based aversion after a 3-yr. period by 8 vervet monkeys (cercopithecus aethiops) was found. the color of the visual cue appeared to effect the retention of the aversion. | 1979 | 119208 |
| vasoactive material present in the glomerula caudalia of the vervet monkey. | complex encapsulated neurovascular structures, glomus organs, occur in superficial and deep positions in many species. no direct evidence for their function exists. in skin they may serve thermoregulation by the reason for their structural complexity remains obscure. the concept of a local humoral circulatory control mechanism postulated on the basis of a very high acetylcholine content reported for human glomera coccygia has been investigated in homologous caudal glomus organs in monkey. no ace ... | 1979 | 116696 |
| social isolation and other behavioral changes in groups of adult vervet monkeys (cercopithecus aethiops) produced by low, nonchronic doses of d-amphetamine. | doses (0.1--0.7 mg/kg body weight) d-amphetamine were administered to three independent groups of green vervet monkeys (cerecopithecus aethiops). each group formed a triad with one male and two females. amphetamine changed both the individual and the social behavior patterns significantly. stereotypy and social isolation (withdrawal) were characteristic features of the amphetaminized animals. also stereotyped social grooming was observed. the results are discussed in relation to behavior changes ... | 1979 | 116271 |
| immunity in plague: protection of the vervet (cercopithecus aethips) against pneumonic plague by the oral administration of live attenuated yersinia pestis. | protection against pneumonic plague by the oral administration of a live, attenuated yersinia pestis vaccine, ev76 (paris) f, was evaluated in the vervet (cercopithecus aethips). six animals were vaccinated with a dose of 1.175 x 10(9) colony-forming units (cfu); all tolerated the dose and developed antibodies to fraction i of y. pestis. three immunized animals were challenged with an inhaled dose of 3.2 x 10(6) cfu (160 ld50 [50% lethal dose]) of virulent y. pestis strain 195/p and two survived ... | 1977 | 402428 |
| behavioral effects of low, acute doses of d-amphetamine on the dyadic interaction between mother and infant vervet monkeys (cercopithecus aethiops) during the first six postnatal months. | doses of d-amphetamine sulfate (0.1, 0.15, and 0.2 mg/kg body weight) were given to adult monkeys in mother-infant pairs. the fundamental parental care behavior pattern was disrupted and the mother became isolated in a socially withdrawn phase. she did not respond to the calling signals of the infant and showed behavior in which stereotyped self-grooming and/or 'staring' into space were predominant. the reactions of the infant to this amphetamine-induced behavior were different in the two experi ... | 1979 | 115045 |
| the effects of orbitofrontal lesions on the aggressive behavior of vervet monkeys (cercopithecus aethiops sabaeus). | | 1979 | 113236 |
| [the influence of endogenous insulin and glucagon on the free fatty acids in the circulating blood plasma]. | the effect of increased endogenous plasma insulin and glucagon concentrations on the free fatty acid (ffa) levels in the circulating blood was investigated in sheep, 2 baboons and 1 vervet monkey. elevation of the plasma insulin level was obtained by vagal stimulation or intravenous glucose administration and vagal stimulation, whereas increased glucagon levels were induced by sympathetic stimulation, increased plasma insulin levels, with simultaneous increased plasma glucose concentrations (in ... | 1979 | 112697 |
| monkeys as metabolic models for man--the fate of amphetamine in the vervet and patas monkey [proceedings]. | | 1979 | 110386 |
| characteristics of the internal anal sphincter and the rectum of the vervet monkey. | 1. the physiology of the internal anal sphincter of the vervet monkey was investigated. 2. strips of sphincter in vitro contracted to noradrenaline and adrenaline; adrenoceptors were mainly alpha-excitatory. strips of rectal circular muscle relaxed to noradrenaline and contained both inhibitory alpha- and beta-adrenoceptors. 3. all strips contracted to acetylcholine. after hyoscine or atropine, high doses of acetylcholine relaxed all strips by stimulating intramural inhibitory neurones as relaxa ... | 1979 | 108393 |
| implications for adult roles from differential styles of mother-infant bonding: an ethological study. | ethological observations of maternal and infant behaviors of nine vervet monkey pairs (cercopithecus aethiops sabaeus) showed the effects of differential styles of early maternal responsiveness on later infant competence. those infants receiving the least amount of maternal responsiveness and the most time-off the mother in the first 3 months of development were more socially competent at 6 months of age. the results are discussed within current ethological "attachment" theories. the detachment ... | 1979 | 105083 |
| polymorphonuclear neutrophilic leukocytes in protein deficiency. | the number of white blood cells and of polymorphonuclear leukocytes remained unchanged in vervet monkeys (cercopithecus aethiops) receiving a "o" protein diet. the motility of the polymorphonuclear leukocytes and their phagocytic and killing indices with and without leukokinin stimulation decreased in protein-depleted animals. acid cathepsin decreased, dna relatively increased, and peroxidase, alkaline phosphatase, acid phenylphosphatase, and lysozyme reached higher levels in the polymorphonucle ... | 1977 | 409270 |
| a cephalometer for craniofacial studies of the vervet monkey. | | 1978 | 103468 |
| the pathology of experimental ebola virus infection in monkeys. | six rhesus and two vervet monkeys were infected intraperitoneally with ebola virus. they developed an acute haemorrhagic fever with skin rash 4 days later and died 6--12 days after infection. histopathological lesions of acute necrosis were present in the liver, spleen, lymph nodes, lungs and testes. the presence of fibrin thrombi in several organs was suggestive of the occurrence of disseminated intravascular coagulation during the infection. | 1978 | 102747 |
| the susceptibility to praziquantel of schistosoma haematobium in the baboon (papio anubis) and of s. japonicum in the vervet monkey (cercopithecus aethiops). | | 1977 | 410180 |
| fiber, lipids, and atherosclerosis. | the influence of dietary fiber on lipid metabolism and atherosclerosis in animals and on lipid metabolism in man is reviewed. pectin, guar gum, and lignin lower serum and liver cholesterol in cholesterol-fed rats. agar increases liver cholesterol in rats. bran has no effect on serum lipid levels in rats or monkeys. vegetarians have long been known to exhibit cholesterol levels lower than those of comparable populations who subsist on a mixed diet. pectin and guar gum lower cholesterol levels in ... | 1978 | 101075 |
| periodontal and pulpal healing of monkey incisors preserved in tissue culture before replantation. | the effect of delayed replantation and tissue culture as a prevention against root resorption was examined in green vervet monkeys (cercopithecus aethiops). extracted incisors were kept in tissue culture medium (eagle's medium) for 5--14 days before replantation. the extra-alveolar dry period before tissue culture ranged from to 0 to 60 min. incisors not subjected to tissue culture served as controls. the animals were sacrificed 8 weeks after replantation. the following histologic parameters wer ... | 1978 | 98456 |
| experimental fractures of monkey mandibles. | forty vervet monkey half mandibles, 20 with unerupted third molars and 20 with erupted third molars, were partially embedded in acrylic and loaded in an instron tensiometer. mandibles with unerupted third molars fractured at 15.8 +/- 2.5 kg while those having erupted third molars fractured at 26.4 +/- 4.2 kg. mandibles having unerupted third molars were shown to be significantly weaker than the mandibles with erupted third molar (t = 8.45, p less than 0.001). | 1978 | 98455 |
| rat lung hyper-reactivity to stress. | rats have been used frequently as a model for determining the pulmonary response to various stressful situations. it has been shown in the literature that rat lungs are remarkably sensitive to factors which result in the development of gross pulmonary injury, such as stress from exposure to hyperbaric oxygen. similarly, a high degree of pulmonary reactivity was found in rats after administration of various cns, convulsants and also exposure to mechanical vibration. the present study was confined ... | 1978 | 414726 |
| circadian rhythm of cholesterol-7alpha-hydroxylase and cortisol in the african green monkey (cercopithecus aethiops). | cholesterol-7alpha-hydroxylase in african green monkey liver had an apparent km of 1.65-10(-4) m cholesterol and a ph optimum of 7.4. the amplitudes of the circadian maxima of enzyme activity and serum cortisol levels were significantly greater in vervets than in grivets. fluctuations in enzyme activity and cortisol levels during the circadian cycle were positively correlated (r = 0.89). enzyme activities and hormone levels were 2.7-fold lower over a 24-h period in the grivet than in the vervet. ... | 1978 | 96863 |
| movement of horseradish peroxidase in the cornea, sclera and the anterior uvea. | the anterior chambers of rabbit, monkey and human eyes were perfused with horseradish peroxidase. the perfusion was started immediately after enucleation of the monkey and human eyes, while the rabbit eyes were perfused in situ after the animals had been killed. comparative results were obtained after 1 h or perfusion and were mainly based on frozen sections. intensive staining was found in the descemet's membrane, the sclera and the iridial stroma, considerably more than in the corneal stroma a ... | 1977 | 71844 |
| hemagglutination inhibition studies for the evaluation of blood group antigens in ethanol soluble substances (ess) obtained from human, baboon and vervet monkey red blood cells. | soluble blood group substances, isolated from the red blood cells of humans, baboons, and vervet monkeys by ethanol extraction, possessed serologically active specificities for the following antigens: a, b, h, lea, lebl, p, p19 pk and i. human red blood cells lacking any of these specificities by the direct hemagglutination test also lacked the related antigens in their soluble extract. the only exception was in "bombay" oh cells, from which soluble h substance could be readily isolated. soluble ... | 1976 | 56065 |
| rift valley fever: the role of the vervet monkey as a reservoir or maintenance host for this virus. | | 1978 | 418540 |
| the effect of oral pancreatic extract on jejunal bactericidal activity in protein-deficient vervet monkeys challenged with vibrio cholerae. | eleven vervet monkeys (cercopithecus aethiops) were fed with an "o" protein diet. after the serum albumin level fell below 2.5 g/100 ml the animals and 4 controls, which received regular monkey chow, were orally infected with a monkey-adapted strain of vibrio cholerae. the total bactericidal activity of the jejunal fluid decreased during feeding with "o" protein diet, but increased after challenge with v. cholerae in all groups. the non-immunoglobulin-bound bactericidal activity, which also decr ... | 1979 | 41422 |
| the electrolyte pattern of the gastric secretion from the vervet monkey. | the output of acid, chloride, sodium and potassium in gastric washings from the vervet monkey have been measured under basal conditions and while stimulating the secretion with two doses of pentagastrin (one dose submaximal, the other dose supramaximal). the output during washings with different weak electrolyte solutions (5 meq/1 nac1, kcl, or hcl or 0.36 m glycine) are compared. the results show that the composition of the secretion was independent of the composition of the rinsing fluid in th ... | 1975 | 5809 |
| the phosphorylation of histones in herpes virus infected vervet-monkey kidney cells (cv-1). | the phosphorylation of histones of the f1 group and of fraction f2a2 is stimulated in monkey kidney cells (cv-1) to almost two times the control values 14 hours after their infection with herpes virus, type 2. at the same time high amounts of viral dna are produced. it seems very likely that the stimulated phosphorylation of these histone fractions is a prerequisite for the enhanced synthesis of dna and possibly also rna. | 1977 | 201899 |
| effect of rhesus or vervet cytomegalovirus infection of dna synthesis in untreated and 5-iodo-2'-deoxyuridine-arrested cells. | infection of permissive cells with either rhesus or vervet cytomegalovirus resulted in suppression of cellular dna synthesis, only viral dna was resolved by isopycnic centrifugation after 24 h postinoculation. infection of 5-iodo-2'-deoxyuridine (iudr)-arrested cells with either of the simian cytomegaloviruses, however, induced synthesis of cellular dna of normal density; synthesis of cellular dna substituted with iudr as evidenced by resolution of a heavy dna peak after isopycnic centrifugation ... | 1978 | 203716 |
| influences of cyclic nucleotides on outflow facility in the vervet monkey. | | 1978 | 215426 |
| some infectious diseases of wild vervet monkeys (cercopithecus aethiops pygerythrus) in south africa. | our surveys indicate that nearly all batches of vervet monkeys arriving at the national institute for virology from various areas of south africa, are infected with foamy viruses and there is evidence that intra-urterine infection also occurs. monkeys from certain areas of south africa are apparently infected with the protozoal parasite entopolypoides macaci in a sub-clinical state which becomes active when the monkeys are splenectomised. serological studies indicate that infections with schisto ... | 1978 | 218005 |
| antibody reactivity to human and vervet cytomegalovirus early antigen(s) in sera from patients with active cytomegalovirus infections and from asymptomatic donors. | human fibroblasts were infected with vervet cytomegalovirus (vcmv) and cultured in medium containing 50 micrograms of cytosine arabinoside per ml for 72 h. early antigens (eag) were detected in the nuclei of infected cells by an indirect fluorescent antibody test with human sera having antibody to eag of human cytomegalovirus (hcmv). sera from patients with serological and/or virological evidence of active hcmv infection and from asymptomatic blood donors were examined for antibody activity with ... | 1979 | 219017 |
| isolation and characterization of high density lipoprotein apoproteins in the non-human primate (vervet). | | 1979 | 221507 |
| the role of laboratory animals in dental research. | in dental research, in common with other forms of scientific research, the use of laboratory animals is necessary to carry out many investigations that may not be undertaken on man, and to control biological variability. in south africa the main experimental animals used in dental research are rats and vervet monkeys, although other species such as dogs and baboons have been used. this paper lists examples of published dental research carried out in laboratory animals in south africa in the fiel ... | 1978 | 370388 |
| perception of conspecific vocalizations by japanese macaques. evidence for selective attention and neural lateralization. | japanese macaques (macaca fuscata) and control species (vervet, pigtailed macaque, bonnet macaque) were trained for food to respond to one class of recorded fuscata vocalizations and do not respond to a second class. a measure of neural lateralization was obtained by presenting the stimuli randomly to the right or the left ear, and comparing performance in the two ears (ear advantage method). vocalizations were from steven green's field tapes. in experiment i, the two classes were green's 'smoot ... | 1979 | 399204 |
| immunity in plague: protection induced in cercopithecus aethiops by oral administration of live, attenuated yersinia pestis. | a live, attenuated yersinia pestis vaccine, designated ev76 (paris) f, was pathogenic in cercopithecus aethiops when administered parenterally. although an oral dose of 10(9) colone-forming units of the vaccine was nonfatal to vervets, a transient but severe gastrointestinal disturbance resulted in four of 12 animals. seven immunized vervets were protected against intradermal challenge. the remaining five vervets without serologic reactions and five untreated controls died from typical bubonic ( ... | 1976 | 815445 |
| pilocarpine-induced subsensitivity to carbachol and pilocarpine of ciliary muscle in vervet and cynomolgus monkeys. | vervet monkeys were given unilateral treatment for two weeks with one 2% pilocarpine eye drop three times daily between 8 a.m. and 6 p.m. (night interval 14h) and were then subjected to anterior chamber perfusion 20 mug pilocarpine intracamerally caused similar and substantial increases in outflow facility in both eyes. cynomolgus monkeys were unilaterally treated with continuous release of 33 mug/h of pilocarpine for 5-6 days. the facility response to 1 mg/kg pilocarpine iv was small or absent ... | 1977 | 402785 |
| experimental replantation of root-canal-filled and untreated teeth in the vervet monkey. | | 1977 | 404381 |
| [effect of orally administered pancreatic extract on vibrio cholerae infection during protein deficiency]. | two groups of 5 and 6 vervet monkeys respectively were fed a protein-free diet. both groups of protein depleted vervets developed a minor decrease of serum and intestinal immunoglobulins, as well as marked impairment of exocrine pancreatic function. thereafter the groups were challenged with vibrio cholerae, while one group received purified pancreatic extract by oral administration. the group without pancreatic extract developed severe and significantly longer lasting diarrhea than the group wi ... | 1977 | 404703 |
| spectral and orientation specificity of single cells in foveal striate cortex of the vervet monkey, cercopithecus aethiops. | 1. the spectral sensitivity, orientation specificity and inhibitory surround of seventy-three cells were studied in the vervet monkey. the eye was in the dark or illuminated with steady white or spectral light. the cells were in the striate cortex corresponding to the foveal representation. nearly all the cells gave on- or on/off-responses.2. more than a third of the cells (41%) responded over a narrow spectral band, in the blue, green, yellow or red section. three quarters of them were orientat ... | 1977 | 406386 |
| atropine inhibition of echothiophate cataractogenesis in monkeys. | one cynomolgus and three vervet monkeys were treated topicall twice daily in one eye with 63 microgram of echothiophate iodide and 750 microgram of atropine sulfate. the opposite eyes were treated with echothiophate alone. the eyes treated with echothiophate alone all developed posterior and/or anterior subcapsular cataracts within 26 to 66 days. the echothiophate plus atropine-treated cynomolgus eye developed a cataracts of much delayed onset and lesser severity compared to its echothiophate-on ... | 1977 | 406884 |
| formazan cells in protein and protein-calorie malnutrition. | formazan cells were less numerous in the peripheral blood of vervet monkeys (cercopithecus aethiops) receiving a "o" protein-low calorie diet than in animals fed a full or a protein but not calorie deficient diet. | 1977 | 409269 |
| experimental autoimmune thyroiditis in the vervet monkey. | autoimmune thyroiditis was induced in two vervet monkeys by immunizing them with human thyroid extract. as expected, both animals developed cytotoxic antibodies which were active against human thyroid and other human cells in tissue culture. in addition, a second serum factor was detected. this was capable of sensitizing human thyroid (and other) cells and rendering them susceptible to killing by normal lymphocytes. this finding implicates antibody-dependent cell-mediated cytotoxicity in the pat ... | 1977 | 409579 |
| pulpal response to a new visible light-cured composite restorative material: fotofil. | a new visible light-cured composite resin, fotofil, has been developed for the esthetic restoration of anterior teeth. the pulpal responses elicited by this material in unlined cavities and cavities lined with dycal were compared with those elicited by a negative control consisting of modified zinc oxide-eugenol cement notebec and a silicate cement syntrex. the pulpal responses were evaluated in the permanent maxillary and mandibular incisors in vervet monkeys using labial claterial in each monk ... | 1977 | 409820 |
| cultivation of periodontal ligament fibroblasts on extracted monkey incisor. a histologic study of three culturing methods. | forty-two permanent incisors were extracted from green vervet monkeys and cultivated in eagle's medium at 37 degrees c using the following culture methods: 1. teeth placed at the bottom of the culture flask; 2. teeth placed in an upright position in the culture flask and supported by an open glass cylinder; 3. teeth placed in an upright position in the culture flask and supported by a semisolid tissue culture medium. the teeth were cultured from 1 to 21 days and then examined histologically and ... | 1977 | 410744 |
| electronmicroscopical characterisation of simian papovavirus sa12. | ultrastructural studies of simian virus sa12, growing in primary cultures of vervet monkey-kidney cells, have demonstrated a typical papovavirus capsid morphology and a diameter of 43 nm. the cytopathic nuclear characteristics, with the absence of virus crstals and elongated capsid forms, distinguish it from sv40 and the human papovaviruses. like other papovaviruses, sa12 shows a strong affinity for cellular membranes. | 1977 | 410936 |
| a histologic study of the response of masticatory and lining mucosa to mechanical loading in the vervet monkey. | | 1978 | 413909 |
| malnutrition and susceptibility to infection with vibrio cholerae in vervet monkeys (cercopithecus aethiops). 2. response of vervet monkeys on protein, b-vitamin complex and calorie-deficient diets to infection. | five groups of vervet monkeys (cercopithecus aethiops) were fed regular monkey chow, low protein (lp), low b-vitamin complex (lbv), lp-lbv, or low protein- low calorie (lp-lc) diets, respectively. after eight weeks the animals were infected with cholera vibrios. igg, iga and igm increased in the sera of all animals after the challenge but the avidity of the immunoglobulins was lower in vervets on lp diets. diarrhea and excretion of vibrios lasted longer in animals consuming less protein. | 1976 | 828672 |
| effect of oral pancreatic enzymes on the course of cholera in protein-deficient vervet monkeys. | the effect of pancreatic extract on the course of cholera infection in protein-deficient vervet monkeys (cercopithecus aethiops) was studied. eleven animals were made protein deficient by diet. thier intestinal pancreatic enzyme concentration decreased as they became protein depleted. these animals were then challenged with vibrio cholerae. four control animals given a standard diet were similarly challenged. immediately after challenge, 6 of the protein-deficient monkeys were given a highly pur ... | 1978 | 415928 |
| histologic response of replanted teeth pretreated with acidulated sodium fluoride. | central incisors in the vervet monkey were extracted, endodontically treated, and replanted into their original sockets after immersion in a 2 per cent acidulated sodium fluoride solution (ph 5.5) for 30 minutes. histologic examination at 1, 2, 4, and 8 weeks postoperatively showed that by the second week resorption had taken place and that ankylosis, first seen by the fourth week, along both the buccal and palatal root surfaces, was well established by the eighth week. under the conditions of t ... | 1978 | 417280 |
| evaluation of live attenuated plague vaccines in praomys (mastomys) natalensis. | a live attenuated yersinia pestis vaccine designated ev76-51f, which had previously been shown to be pathogenic in vervet monkeys but not in guinea pigs, was tested in the multimammate mouse praomys (mastomys) natalensis. doses of 10(6) viable organisms inoculated subcutaneously as either a lyophilized suspension or an agar-grown culture resulted in vaccination fatalities in praomys but not in white mice. hemagglutinating antibodies to the fraction 1 antigen were not stimulated by doses lower th ... | 1977 | 908624 |
| ebola haemorrhagic fever: experimental infection of monkeys. | experimental infection of rhesus and vervet monkeys with ebola virus produced a uniformly fatal illness. the course of the disease resembled that found in man with weight loss, anorexia, fever, haemorrhages and skin rash being frequently seen. viraemia was obvious within two days of infection and persisted until death which occurred between days five and eight. virus was found in high concentrations in several organs but particularly in the liver, spleen, and lungs. | 1978 | 418537 |
| synthesis of catecholamines in the eye after local injection of 3h-precursors. | the possibility that adrenaline may be synthesized locally in the eye was investigated in the rabbit and vervet monkey. l-tyrosine-3,5-3h, l-tyrosine (side-chain-2,3-3h) or l-3,4-dihydroxyphenylalanine (3h(g)) was injected into the anterior chamber or the vitreous. the animals were killed after 1/2 h up to 7 days in the tyrosine experiments and after 1 up to 24 h in the dopa experiments. the synthesis of 3h-adrenaline, 3h-noradrenaline and 3h-dopamine was measured with a modified version of a do ... | 1975 | 809997 |
| cellular responses of vervet monkeys (cercopithecus aethiops) experimentally infected with leishmania major. | | 1992 | 1307757 |
| ci-744 anesthesia for ophthalmological examination and surgery in monkeys. | ci-744 is a new agent for chemical restraint and surgical anesthesia in animals, consisting of equal parts by weight of the cataleptoid agent tiletamine-hcl and the tranquilizer zolazepam-hcl. we have used it in the intramuscular dose of five to ten milligrams per kilogram to anesthetize 110 cynomolgus and 10 vervet monkeys a total of 1,500 times for various ophthalmological procedures. at these dosages its characteristics of action were rapid onset, thirty of fifty minutes of surgical depth ane ... | 1975 | 810453 |
| induction of subcapsular cataracts in aniridic vervet monkeys by echothiophate. | four surgically aniridic vervet monkeys with clear lenses received topical echothiophate iodide unilaterally daily for eight weeks. the opposite eyes received a control solution without echothiophate. all the echothiophate-treated eyes developed subcapsular lens opacities sttongly resembling those attributed to echothiophate in humans. the lenses in the control eyes remained clear. | 1975 | 810455 |
| reproduction in captive vervet and sykes' monkeys. | | 1975 | 810535 |
| behavioral effects of thymoleptics in vervet monkeys (cercopithecus aethiops). | desmethylimipramine (dmi) exerts diverse quantitative effects on the gross behaviour of monkeys. excitatory as well as sedative effects were observed, which varied according to the general animal temperament. results resembling those obtained with dmi were observed using chlorimipramine and iprindole, although the effects of iprindole were less marked. chlorimipramine also produced immobilization and postural change. the results are discussed in relation to behavioral effects of thymoleptics in ... | 1975 | 810822 |
| effects of artificial intraocular pressure elevation on the corneal endothelium in the vervet monkey (cercopithecus ethiops). | both eyes of anesthetized vervet monkeys were perfused with mock aqueous humor for 3-7 hours. by adjusting the height of a reservoir connected to the anterior chamber of each eye the intraocular pressure in one eye was maintained at 33-44 mmhg and in the other eye it was a few mmhg above the spontaneous level (12-15 mmhg). morphologically the control eyes appeared normal, whereas pronounced changes were observed in the high pressure eyes. thus the corneal endothelium showed an uneven surface tow ... | 1975 | 813491 |
| the cephalometric analysis of cercopithecus aethiops. | a steiner-based cephalometric study of 46 adult vervet monkeys was undertaken using craniometric points as closely correlated to those in the human as possible. on tracings of each cephalogram 13 measurements were recorded. the results were statistically analysed. whilst the monkey face does vary individually this variation is apparently much less than is that of the human face. it is possible that the positions of the monkey incisor crowns bear a relatively constant relationship to the soft tis ... | 1976 | 813528 |
| biliary excretion of sterigmatocystin by vervet monkeys. | | 1976 | 817724 |
| ifn-gamma and delayed-type hypersensitivity are associated with cutaneous leishmaniasis in vervet monkeys following secondary rechallenge with leishmania major. | ifn-gamma levels and delayed-type hypersensitivity (dth) responses were evaluated in vervet monkeys, following secondary infection with leishmania major (l. major). the animals had previously been vaccinated with leishmanial antigen, exposed to a primary infection and allowed to self-cure. supernatants of peripheral blood mononuclear cell (pbmc) cultures, stimulated with either l. major antigen or concanavalin a (con a), were examined for the presence of ifn-gamma in a double sandwich enzyme-lin ... | 1992 | 1514049 |
| standardization of escherichia coli oral vaccines. | the proof of the efficacy of a vaccine can be rendered only by field trials. nevertheless, a number of in vitro and in vivo tests has to be employed before large-scale testing can be carried out. this particularly holds true about vaccines used to prevent intestinal infections, which were the center of our interest. seven strains, four of them causing diarrhea in man, and three in animals, have been investigated as potential oral immunizing agents. the strains were made apathogenic by heating, ... | 1976 | 821801 |
| representation of fovea in the striate cortex of vervet monkey, cercopithecus aethiops pygerythrus. | | 1976 | 822583 |
| microscopic organization of the ligamenta flava in cercopithecinae. | the ligamenta flava have been investigated in cercopithecus pygerythrus (vervet monkey) and c. mitis (blue monkey) at various levels of the vertebral column. it has been shown that in the cervical, thoracic and lumbar regions the topography of these ligaments differs. the cervical ligamenta flava do not extend over the intervertebral joints, while in the thoracic and lumbar regions they reinforce and fuse with the capsule. the ligamenta flava from t4 to s1 replace the interspinous ligaments by e ... | 1976 | 822678 |
| [comparison between the spatial behavior of enamel and dentin crown contour in the cercopithecus aetiops pygerytrus (vervet monkey)]. | | 1976 | 823636 |
| the diencephalon of the vervet monkey (cercopithecus aethiops). part i: thalamus and metathalamus. | the diencephalon of the vervet monkey (cercopithecus aethiops) is described and compared with that of other primates, particularly the macaque monkey (macaca mulatta). in the vervet monkey, the thalamus is divided into six nuclear groups: anterior, midline, medial, dorsolateral, ventrolateral and posterior. the anterior nuclear group shows a regressive nucleus anterodorsalis and a poorly defined demarcation between the nuclei anteromedialis and anteroventralis. there is a large interthalamic adh ... | 1976 | 823649 |
| the diencephalon of the vervet monkey (cercopithecus aethiops). part ii: epithalamus, subthalamus and hypothalamus. | the nuclear configuration and topography of the epithalamus, subthalamus and hypothalamus of the vervet monkey (cercopithecus aethiops) are described and compared with those of other primates, particularly the macaque monkey. the epithalamus does not show any striking structural differences, except some architectonic differentiation in the lateral habenular nucleus. the subthalamus is a phylogenetically stable structure throughout the primate scale; it does not show any significant changes, exce ... | 1976 | 823650 |
| mycotoxic peripheral myelinopathy, myopathy, and hepatitis caused by diplodia maydis in vervet monkeys. | during recent historical times many africans changed their diet to one based on maize. the grain is regularly contaminated by fungi which are toxigenic to domestic animals and birds. after one of the fungi, diplodia maydis, in pure culture on maize, was added to the food of omnivorous primates there was demyelination of nerves, atrophy, degeneration and necrosis of muscle, and hepatitis. these preliminary results are applicable to veterinary and laboratory animal sciences. they may also be medic ... | 1991 | 1656046 |
| the influence of traumatic intrusion of primary teeth on their permanent successors. a radiographic and histologic study in monkeys. | intrusion of maxillary central primary incisors was performed in 18 green vervet monkeys (cercopithecus aethiops) with the purpose of studying early and late histologic changes in odontogenesis of permanent tooth germs and the effect of treatment of primary tooth injury. immediate changes were studied in five monkeys where both maxillary central primary incisors were intruded. the monkeys were sacrificed 10-15 min after intrusion. the immediate changes in the permanent tooth germ consisted of co ... | 1976 | 824213 |
| subsensitivity to pilocarpine of the aqueous outflow system in monkey eyes after topical anticholinesterase treatment. | cynomolgus and vervet monkeys were treated unilaterally with topical echothiophate iodide twice daily for eight to 25 weeks. the effect of intracameral pilocarpine on outflow facility was determined in the ganglionic-blocked animal during and after echothiophate treatment. the echothiophate-treated eyes demonstrated marked subsensitivity to pilocarpine, and required several weeks to months to recover normal pilocarpine sensitivity. | 1976 | 826164 |
| malnutrition and susceptibility to infection with vibrio cholerae in vervet monkeys (cercopithecus aethiops). 1. induction of protein, b-vitamin complex and calorie malnutrition. | five groups of eight vervet monkeys (cercopithecus aethiops) were fed regular monkey chow, low protein (lp), low b-vitamin complex (lbv), low protein - low b-vitamin complex (lb-lbv), or protein - low calorie (lp-lc) diet, respectively, for eight weeks. hematocrit values, hemoglobin, bun, total protein, albumin, riboflavin and body weight decreased, the ratio of dispensable/indispensable amino acids increased in all animals receiving a deficient diet. total globulin, igg and igm remained unchang ... | 1976 | 826634 |
| control of scrotal colour in the vervet monkey. | the vervet monkey has a vivid blue scrotum which pales when the animal falls in social rank. histology and electron microscopy showed dopa-positive melanocytes in the dermis each packed with fully melanised melanosomes. by transmitted light the scrotal skin was brown on a red background: by reflected light the colour was blue. thus the blue colour is due to tyndall scattering over a layer of melanin. variation of scrotal colour was not due to changes in melanocyte number or dispersion of melanos ... | 1976 | 828671 |
| a study of the connective tissue surrounding the developing tooth in the vervet monkey. | | 1975 | 829821 |
| 3,4-dihydroxyphenylacetic acid and homovanillic acid in rat plasma: possible indicators of central dopaminergic activity. | the concentrations of dopamine (da) metabolites (free and conjugated) was measured in plasma and brain regions of rats by the mass spectrometric method of selected ion monitoring. experimental treatments which altered the function of central dopamine neurons also induced concomitant changes in plasma 3,4-dihydroxyphenylacetic acid (dopac) and homovanillic acid (hva). stimulation of the nigrostriatal pathway increased plasma dopac and hva whereas lesion of the pathway decreased plasma metabolites ... | 1979 | 477719 |
| reinfection of vervet monkeys (cercopithecus aethiops) with borrelia hermsii. | two of 4 untreated vervet monkeys infected with borrelia hermsii survived and were resistant to reinfection for at least 1 year. seven of 9 vervets receiving tetracycline could be reinfected after 12 to 36 weeks. immobilizine could be demonstrated for a shorter time in treated than in untreated vervets. | 1975 | 807959 |
| effects of benzalkonium chloride upon the corneal epithelium studied with scanning electron microscopy. | the corneal surface of rabbits and vervet monkeys was studied by means of scanning electron microscopy after the influence of the cationic surfactant, benzalkonium chloride. the concentration of the drug was 0.02% or 0.01% and the exposure time was 2 or 4 min. the corneas treated with the drug had characteristic changes with small holes or more extensive lesions of the superficial cell membranes, and loss of microvilli or microplicae. the damage was considered to be due to the lytic effect of be ... | 1975 | 809982 |
| natural hosts of hepatitis a virus. | the host range for hepatitis a virus (hav) is limited to man and several species of non-human primates, and involvement of vertebrates other than primates in hav circulation is unlikely. spontaneous hepatitis a infection has been reported to occur in captive non-human primates including the great apes (chimpanzee) as well as old world (cynomolgus, african vervet, stump-tailed) and new world (aotus) monkeys. the presence of anti-hav antibody in the sera of newly captured monkeys of these species ... | 1992 | 1335654 |
| comparison of the effect of the amount and degree of unsaturation of dietary fat on plasma low density lipoproteins in vervet monkeys. | the effects of the degree of unsaturation and of the amount of dietary fat on low density lipoprotein (ldl) concentration and composition were determined in vervet monkeys. diets with fat contents of 41, 31 and 18% energy, each with a low and a high polyunsaturated to saturated fatty acid ratio (p/s; 0.27-0.38 and 1.13-1.47) were fed to six female vervet monkeys for two months. another six females were given a low fat, high p/s diet for the same period of time, to serve as a reference. the chole ... | 1992 | 1435092 |
| silhouettes elicit alarm calls from captive vervet monkeys (cercopithecus aethiops). | in part 1, we analyzed alarm calls produced by captive vervets (cercopithecus aethiops) in response to naturally occurring stimuli. females and juveniles regularly alarm called to airplanes, birds, and barking dogs. juvenile females accounted for 60% of these alarm calls. in part 2, we isolated several monkeys from the colony and presented them with life-sized silhouettes of a leopard, snake, eagle, baboon, vervet, and goose. adult monkeys alarm called more than did juveniles. alarm calls were e ... | 1992 | 1451417 |
| hormonal vaginal cytology of vervet monkeys. | the cellular proliferation and maturation of the vaginal epithelium of adult female vervet monkeys was examined during their menstrual cycles. at the same time the serum contents of estrogen and progesterone were analysed. gradual but distinct patterns demarcated the phases of the menstrual cycle cytologically. the karyopyknotic index paralleled the estrogen concentration. mid-cycle peak maturation produced many anucleate squames, which exfoliated, forming a diagnostic vaginal discharge. | 1991 | 2051464 |
| the brachial plexus in the vervet monkey (cercopithecus pygerythrus). | the brachial plexus in ten embalmed, mature vervet monkeys was dissected to document the structure and branching pattern of this nerve plexus in this frequently used research animal. in general, the brachial plexus in the vervet monkey was similar to the plexus of other old world monkeys. however, several aspects were comparable to those observed in domestic animals. thus the quadrupedal and bipedal abilities of the vervet monkey was reflected in the structure of its brachial plexus. | 1991 | 2051467 |
| in vivo measurement of atrial natriuretic peptide receptors using nuclear imaging. | we have successfully visualized atrial natriuretic peptide (anp) receptors in vivo using nuclear imaging. 123i-labelled anp, injected in green vervet monkeys, was rapidly bound to anp receptors in the kidneys and lungs. that the observed uptake was receptor mediated was demonstrated with competition studies using simultaneous injection of unlabelled anp 99-126. it was possible to distinguish between the anp receptor subtypes by the use of selective antagonists. thus coinjection of anp 102-121-de ... | 1992 | 1457086 |
| the influence of fish oil supplementation on plasma lipoproteins and arterial lipids in vervet monkeys with established atherosclerosis. | there is controversy about whether supplementing diets with marine fish oil can regress, promote or prevent atherosclerosis. therefore the effects of an atlantic pilchard oil (fo) supplement and dietary change were measured in a proven atherosclerosis model. vervet or african green monkeys were fed an atherogenic diet (ad) for long enough to ensure progression before treatments started. matched groups were then treated for 20 months, either by adding fo to the ad (ad/fo), or by changing to a the ... | 1992 | 1461923 |
| reinnervation of autotransplanted teeth. a histological investigation in monkeys. | the reinnervation of 8 autotransplanted teeth in 4 green vervet monkeys (ceropithecus aethiops) was examined. the lateral maxillary incisors of each animal were extracted and transplanted to the contralateral side. the root formation was incomplete with an open apical foramen. the monkeys were killed 1, 2 or 4 months after transplantation and examined histologically by a s-100 monoclonal antibody staining. a few single nerve fibres could be seen 1 month after transplantation. after 2 months, sev ... | 1990 | 2120368 |
| reactivity of some monoclonal antibodies specific for human lymphocytes with vervet monkey peripheral blood mononuclear cells. | reactivities of some monoclonal antibodies to human lymphocyte surface antigens were tested on vervet monkey peripheral blood mononuclear cells (pbmc), using flow cytometry and immunoperoxidase techniques. a number of antibodies were identified which reacted with similar populations of lymphocytes from vervet monkeys. these included antibodies that define t cells, suppressor/cytotoxic cell subset, pan b cells, monocytes and mhc class i and ii. a number of anti-cd4 markers examined were unsuitabl ... | 1992 | 1514041 |
| 4,6-dibenzamidopyrazolo[3,4-d]pyrimidine is a highly selective inhibitor of cytomegalovirus adsorption to cells. | the heterocycle, 4,6-dibenzamidopyrazolo[3,4-d]pyrimidine (dbapp), inhibited cytopathology induced by human, mouse, and vervet monkey cytomegaloviruses (cmv) in vitro at 0.2 to 0.5 microm, but did not inhibit cell replication at less than or equal to 30 microm. herpes simplex viruses were unaffected by the inhibitor. the antiviral agent ganciclovir was effective against these cmvs at 3-10 microm in parallel assays. dbapp and ganciclovir were synergistic inhibitors when used in combination. the h ... | 1990 | 2159260 |
| vaccination of the vervet monkey (cercopithecus aethiops) against infection with schistosoma mansoni. | pilot experiments were carried out to assess the immunizing potential of radiation-attenuated cercariae of s. mansoni. groups of 4 monkeys each were vaccinated 4-5 times at 3-5-week intervals using cercariae which had received 10, 20, 40 or 60 krad of gamma radiation. animals were vaccinated with 1000 or 2000 cercariae per kilogram of body weight. overall the difference in worm burdens between the vaccinated and unvaccinated groups was highly significant (p greater than 0.01). the highest level ... | 1992 | 1514046 |
| further evidence for the role of supraspinatus in quadrupedal monkeys. | differences in the degree of projection of the greater tubercle above the level of the humeral head in primate proximal humeri have been associated with differing leverage requirements for supraspinatus during arboreal vs. terrestrial quadrupedal locomotion. since most workers have assumed that supraspinatus acts as a humeral protractor, interpretations of the variation in greater tubercle height have focused on the need for powerful vs. rapid humeral protraction during the swing phase of quadru ... | 1992 | 1562062 |
| synaptic contacts of a two-cone flat bipolar cell in a primate retina. | the golgi-stained dendrites of a two-cone bipolar cell of a vervet monkey were serially sectioned for electron microscopy and shown to make basal synapses with two neighboring cones. the synapses were all on the cone pedicle membrane adjacent to the bipolar processes invaginating to form the triads. this is the characteristic position for flat midget bipolar cells. the numbers of triads in nine adjacent cone pedicles were not significantly different from those in the cones contacted by the bipol ... | 1992 | 1562572 |
| encephalitis and chorioretinitis associated with neurotropic african horsesickness virus infection in laboratory workers. part iv. experimental infection of the vervet monkey (cercopithecus pygerythrus). | neurotropic vaccine strains of african horsesickness (ahs) virus types 1 and 6 were implicated as the possible aetiological agents in 4 cases of encephalitis and uveochorioretinitis in laboratory workers accidentally exposed to the freeze-dried vaccine preparations of the virus. to date, ahs virus has not been known to infect man. to ascertain whether or not primates were susceptible to infection with ahs virus, vervet monkeys (cercopithecus pygerythrus) were inoculated, either transnasally or i ... | 1992 | 1574749 |
| serial morphological changes in primate skeletal myofibres after 3 hours of ischaemia and 24 hours of reperfusion. | the sequential morphological changes occurring in skeletal myofibres after 3 hours' ischaemia and from 3 hours to 24 hours of reperfusion in vervet monkeys are described. eight vervet monkeys were studied under general anaesthesia. a hind limb was exsanguinated and a tourniquet applied for 3 hours. open muscle biopsy specimens were obtained from the tibialis anterior muscle before tourniquet application, just before tourniquet release and 3, 6, 12, 18 and 24 hours after tourniquet deflation. all ... | 1992 | 1574750 |