| isolation of actinobaculum schaalii and actinobaculum urinale from a patient with chronic renal failure. | we report on the isolation of two species of actinobaculum from blood culture of a patient with chronic renal failure. the two isolates were distinct with regard to their morphological and biochemical characteristics. subsequent 16s rrna gene sequencing classified the two species as actinobaculum schaalii and a. urinale. | 2005 | 16000509 |
| ten cases of actinobaculum schaalii infection: clinical relevance, bacterial identification, and antibiotic susceptibility. | nine of 10 strains of actinobaculum schaalii caused urinary tract infections in predisposed individuals. identification included 16s rrna gene sequence analysis and use of the api coryne and rapid id 32 a test systems. a. schaalii is easily overlooked due to its slow growth in ambient air and its resemblance to the normal bacterial flora on skin and mucosa. | 2005 | 16208004 |
| urosepsis with actinobaculum schaalii and aerococcus urinae. | actinobaculum was isolated from urine only after prolonged incubation in 5% co(2) after discrepancy between urine gram stain and initial culture results was observed. additional patients were diagnosed using this method. the prevalence of actinobaculum species in urinary tract infections is underestimated since it is not isolated by routine urine culture procedures. | 2006 | 16455938 |
| actinobaculum schaalii: a common cause of urinary tract infection in the elderly population. bacteriological and clinical characteristics. | to-date only 21 clinical cases of actinobaculum schaalii infection have been published, and a. schaalii has been considered a rare cause of urinary tract infection (uti) and urosepsis. between y 2005 and 2008, we isolated a. schaalii from 55 predisposed elderly patients. in these cases, microscopic findings of coccoid rods in wet smears of urine gave rise to clinical suspicion and subsequently to its isolation from urine. typically only scant growth of a. schaalii occurred after incubation of th ... | 2010 | 19883165 |
| actinobaculum schaalii, a common uropathogen in elderly patients, denmark. | actinobaculum schaalii can cause urinary tract infections and septicemia but is difficult to identify by cultivation. to obtain a fast diagnosis and identify a. schaalii, we developed a taqman real-time quantitative pcr. routine urine samples were obtained from 177 hospitalized patients and 75 outpatients in viborg county, denmark, in 2008-2009. the pcr detected a. schaalii in 22% of samples from patients >60 years of age. this assay showed that a. schaalii is more common than implied by routine ... | 2010 | 20031046 |
| first report of actinobaculum schaalii urinary tract infection in north america. | a recurrent urinary tract infection with actinobaculum schaalii, a fastidious, facultative anaerobic, and emerging pathogen, is described. diagnosis was delayed when routine urine cultures were initially performed yielding recurrently negative results. resolution of symptoms occurred after anaerobic cultures were done to allow organism isolation, identification, and appropriate antimicrobial treatment. | 2010 | 20542207 |
| endocarditis caused by actinobaculum schaalii, austria. | | 2010 | 20587200 |
| actinobaculum schaalii: clinical observation of 20 cases. | clin microbiol infect abstract: actinobaculum schaalii is a new species that has so far been isolated from human blood, urine and pus. its importance has probably been underestimated and other actinobaculum spp. may also have been underdiagnosed. this retrospective study comprises all known cases of a. schaalii infections identified since 2004 in the canton of neuchâtel (170 000 inhabitants), switzerland. strains were cultivated and isolated in the bacteriology laboratory using its routine proce ... | 2010 | 20854424 |
| in vitro susceptibility of actinobaculum schaalii to 12 antimicrobial agents and molecular analysis of fluoroquinolone resistance. | to assess the in vitro susceptibility of actinobaculum schaalii to 12 antimicrobial agents as well as to dissect the genetic basis of fluoroquinolone resistance. | 2010 | 20952417 |
| [urinary tract infection caused by actinobaculum schaalii in an elderly patient]. | | 2011 | 21412672 |
| in vitro susceptibility of actinobaculum schaalii to mecillinam. | | 2011 | 21712238 |
| antimicrobial susceptibility of clinical isolates of actinomyces and related genera reveals an unusual clindamycin resistance among actinomyces urogenitalis strains. | patterns of antimicrobial susceptibility in actinomyces and related genera are very limited in the literature. data of predominant susceptibility profiles could contribute to the establishment of an accurate empirical treatment. | 2017 | 28109846 |
| actinobaculum schaalii in urological patients, screened with real-time polymerase chain reaction. | abstract objective. actinobaculum schaalii can cause urinary tract infections (utis) and occasionally septic complications. it is a carbon dioxide-requiring gram-positive rod which is overlooked if urine is cultured in ambient air or if there is growth of conventional species. this study aimed to find the frequency of a. schaalii in consecutive cohorts of patients with kidney stones, children with suspected uti and patients with indwelling catheters. material and methods. a quantitative real-tim ... | 2011 | 21767246 |
| [emerging uropathogens: point for urologists and biologists]. | technological advances during the last years in bacterial identification by molecular biology and mass spectrometry, or matrix assisted laser desorption ionisation-time of flight (maldi-tof) have allowed identifying new bacteria involved in urinary tract infections. the purpose of this review is to familiarize clinicians with these bacteria so that they can look at a particular target population and help biologists to suspect and identify them. | 2015 | 25726694 |
| the status of the species actinobaculum massiliense (greub and raoult 2006). request for an opinion. | a recent study on members of the genus actinobaculum revealed that cultures of the species actinobaculum massiliense ccug 47753(t) ( = dsm 19118(t)) currently being distributed do not conform to the properties of the type strain of a. massiliense cip 107404(t) given by greub & raoult [greub, g. & raoult, d. (2002). j clin microbiol 40, 3938-3941]. the original strain, cip 107404(t) is no longer available from the biological resource center of institut pasteur, paris. based on data currently avai ... | 2015 | 25479952 |
| recommendations for optimal detection and identification of actinobaculum schaalii in urine. | | 2014 | 25356477 |
| complete genome sequence of actinobaculum schaalii strain ccug 27420. | complete genome sequencing of the emerging uropathogen actinobaculum schaalii indicates that an important mechanism of its virulence is attachment pili, which allow the organism to adhere to the surface of animal cells, greatly enhancing the ability of this organism to colonize the urinary tract. | 2014 | 25189588 |
| [actinobaculum schaalii infection]. | | 2014 | 25022889 |
| skin and soft-tissue infections caused by actinobaculum schaalii: report of two cases and literature review. | skin and soft-tissue infections (sstis) caused by actinobaculum spp. are very rare. in the present study, we report two cases and review the literature. the first case was an immunocompromised patient with an extensive cellulitis secondary to an inguinal abscess, and the second case was a patient with a pilonidal abscess. clinical outcomes of both patients were good after surgical drainage and treatment with cloxacillin. the review of the literature showed that sstis caused by actinobaculum spp. ... | 2014 | 24923266 |
| bacteraemia caused by actinobaculum schaalii: an overlooked pathogen? | actinobaculum schaalii is a uropathogen resistant to ciprofloxacin and trimethoprim-sulfamethoxazole. it requires a long culture time and specific conditions, and is therefore easily overgrown by other bacteria and regarded as part of the normal bacterial flora. we review 17 cases of a. schaalii bacteraemia, demonstrating its invasive potential. a. schaalii should always be ruled out as causative agent in patients with urinary tract infection or urosepticaemia with treatment failure. | 2014 | 24840345 |
| erm(x)-mediated resistance to macrolides, lincosamides and streptogramins in actinobaculum schaalii. | actinobaculum schaalii is a gram-positive bacillus increasingly reported as a causative agent of urinary tract infections as well as invasive infections, mainly in the elderly and patients with underlying urological conditions. since little is known about the molecular basis of antimicrobial resistance in a. schaalii, the aim of this study was to investigate resistance to macrolides, lincosamides and streptogramins (mls) in this emerging pathogen. | 2014 | 24710027 |
| is there a need for bacterial endocarditis prophylaxis in patients undergoing urological procedures? | heart valve repair or replacement is a serious problem.the focused update on infective endocarditis of american college of cardiology/american heart association 2008 (acc/aha guidelines) and guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009) of the european society of cardiology (esc guidelines) describe prophylaxis against infective endocarditis as not recommended for urinary tract procedures in the absence of active infection. a statistical asso ... | 2014 | 24566724 |
| actinobaculum schaalii causing urinary tract infections: report of four cases from argentina. | actinobaculum schaalii may be a more common urinary tract pathogen than previously described. here we report four cases of a. schaalii utis and we also propose a simple identification scheme to be used in the conventional microbiology laboratory based on standard biochemical tests. | 2014 | 24518637 |
| a rare case of histopathological bladder necrosis associated with actinobaculum schaalii: the incremental value of an accurate microbiological diagnosis using 16s rdna sequencing. | we describe here a rare case of bladder wall necrosis associated with actinobaculum schaalii in a 72-year-old patient with non-muscle-invasive bladder cancer (nmibc). a. schaalii microbiological diagnosis requires high index of suspicion and accurate identification methods such as 16s rdna sequencing or maldi-tof mass spectrometry. | 2014 | 24487002 |
| actinobaculum schaalii recurrent urinary infection in a centenarian patient. | | 2013 | 23819633 |
| actinobaculum schaalii causing epididymitis in an elderly patient. | actinobaculum schaalii is a gram-positive coccoid rod that causes various infections in humans and is easily overlooked in cultures. a. schaalii has long been thought to be of low prevalence and limited invasive potential, causing benign cystitis in elderly patients with underlying urological conditions. here, we report the first case of epididymitis caused by this bacterium. | 2013 | 23682167 |
| vertebral osteomyelitis caused by actinobaculum schaalii: a difficult-to-diagnose and potentially invasive uropathogen. | we report the first case of vertebral osteomyelitis caused by actinobaculum schaalii and review all cases of a. schaalii identified at our institution between 2002 and 2005. a. schaalii causes urinary tract infections - especially in elderly people - occasionally with septic complications. | 2007 | 17618471 |
| pyelonephritis caused by actinobaculum schaalii in a child with pyeloureteral junction obstruction. | reported here is the case of a 5-year old boy with a pyeloureteral junction (puj) obstruction and pyelonephritis caused by actinobaculum schaalii, an actinomyces-like organism. pyelonephritis or any other urinary tract infection caused by actinobaculum schaalii has not been described in children before. the patient responded well to pyeloplasty in combination with antibiotic treatment. | 2003 | 12811591 |
| actinobaculum schaalii as a uropathogen in immunocompromised hosts. | | 2012 | 22976256 |
| actinobaculum schaalii an emerging pediatric pathogen? | actinobaculum schaalii was first described as a causative agent for human infection in 1997. since then it has mainly been reported causing urinary tract infections (uti) in elderly individuals with underlying urological diseases. isolation and identification is challenging and often needs molecular techniques. a. schaalii is increasingly reported as a cause of infection in humans, however data in children is very limited. | 2012 | 22928807 |
| [actinobaculum schaalii infection]. | | 2012 | 22749060 |
| [severe phimosis as cause of urosepsis with actinobaculum schaalii]. | actinobaculum schaalii is a small, gram-positive, facultative anaerobic, co2-requiring rod. it is now an acknowledged uropathogen, but often overlooked because of its slow growth. it is part of the normal bacterial flora in the urogenital area, but can be the cause of both local and invasive infections. we present a case of a. schaalii urosepsis in a 68-year-old male with phimosis caused by a severe lichen sclerosus et atrophicus. the only bacteria found in blood and urine was a. schaalii. | 2012 | 22668653 |
| actinobaculum schaalii: an emerging uropathogen? | a. schaalii is a rare uropathogen. we report urosepsis with actinobaculum schaalii detected serendipitously in blood and urine culture in a 79-year-old with urinary tract obstruction. this paper illuminates the flaws in our current system in detecting a. schaalii and raises awareness among clinicians and laboratory teams. | 2012 | 22606634 |
| actinobaculum urinale sp. nov., from human urine. | a hitherto undescribed actinomyces-like bacterium was isolated from human urine. based on its biochemical characteristics, the unidentified bacterium did not correspond to any currently described actinomyces species or related taxa. comparative 16s rrna gene sequencing showed that the unknown bacterium exhibits a specific phylogenetic association with the genus actinobaculum, but a sequence divergence of > 5% from the two currently recognized members of this genus, actinobaculum schaalii and act ... | 2003 | 12807186 |
| "actinobaculum massiliae," a new species causing chronic urinary tract infection. | we report on a new actinobaculum species, "actinobaculum massiliae," isolated from the urine of an elderly woman with recurrent cystitis. its phenotypic pattern was similar to those of both of the other actinobaculum species described to date. on 16s rrna sequencing, the marseille isolate shared 95% homology with actinobaculum suis, 92 to 93% homology with actinobaculum schaalii, 91 to 92% homology with arcanobacterium spp., and 87 to 90% homology with actinomyces species. a bootstrap value of 9 ... | 2002 | 12409355 |
| characterization of some actinomyces-like isolates from human clinical specimens: reclassification of actinomyces suis (soltys and spratling) as actinobaculum suis comb. nov. and description of actinobaculum schaalii sp. nov. | five strains of a hitherto unknown actinomyces-like bacterium were isolated from human clinical sources, including blood cultures. biochemical and chemotaxonomic characterization indicated that the strains were distinct from previously described actinomyces and arcanobacterium species. a comparative 16s rrna gene sequence analysis demonstrated that the undescribed strains constitute a new subline within the actinomyces-arcanobacterium species complex. the closest known relative of the isolates w ... | 1997 | 9226926 |
| actinobaculum schaalii bacteremia: a report of two cases. | we report two cases of bacteremia with actinobaculum schaalii, a rarely reported, anaerobic, gram-positive bacterium. the first case was a patient with renal cancer who developed pyelonephritis after cryoablation, and the second was a patient who developed sepsis after a urogenital procedure. bacteremia resolved after administration of empiric antibiotic therapy. | 2015 | 25881498 |
| a validation of the danish microbiology database (miba) and incidence rate of actinotignum schaalii (actinobaculum schaalii) bacteraemia in denmark. | actinotignum schaalii (former named actinobaculum schaalii) can cause urinary tract infections (utis) and bacteraemia, mainly in the elderly. a. schaalii is difficult to identify with conventional biochemical tests, and it is often overlooked if the urine is only cultured in ambient air. the aim of this study was to validate data from the nationwide danish microbiology database (miba) with data from the laboratory information system (lis) at the local department of microbiology in viborg-herning ... | 2015 | 26319901 |
| infections related to actinotignum schaalii (formerly actinobaculum schaalii): a 3-year prospective observational study on 50 cases. | | 2016 | 26551841 |
| actinotignum schaalii (formerly actinobaculum schaalii): a newly recognized pathogen-review of the literature. | the genus actinotignum contains three species, actinotignum schaalii (formerly actinobaculum schaalii), actinotignum urinale and actinotignum sanguinis. a. schaalii is the species most frequently involved in human infections, with 172 cases, mostly urinary tract infections (utis), reported so far. invasive infections have also been described. this facultative anaerobic gram-positive rod is part of the urinary microbiota of healthy patients. it is responsible for utis, particularly in elderly men ... | 2016 | 26577137 |
| actinobaculum schaalii, a new cause of knee prosthetic joint infection in elderly. | actinobaculum schaalii is an emerging pathogen particularly involved in urinary tract infection of elderly people and/or patient with urological risk factors of urinary tract infection. this microorganism is a difficult-to-diagnose pathogen and is rarely involved in systemic or deep infections. here, we report the first case of prosthetic joint infection due to a. schaalii in an 84-year-old man with a benign prostatic hyperplasia associated with chronic retention of urine. this case underlines t ... | 2016 | 26680782 |
| [actinotignum schaalii (formerly actinobaculum schaalii): a new cause of balanitis]. | | 2016 | 27080098 |
| actinotignum (formerly actinobaculum) schaalii: a review of maldi-tof for identification of clinical isolates, and a proposed method for presumptive phenotypic identification. | actinotignum schaalii is a recognised cause of urinary tract infection. following a case of urosepsis, 20 isolates of a. schaalii were collected over an initial 18 month period from urine and blood culture. an additional 25 isolates were collected over the following 13 months. actinotignum schaalii had likely been overlooked or dismissed as a contaminant in our laboratory prior to this study period. it grows slowly on blood agar with supplemental co2 or anaerobically. it may not grow on macconke ... | 2016 | 27131934 |
| sulphonamide resistance associated with integron derivative tn6326 in actinotignum schaalii. | | 2016 | 27261268 |
| unusual clinical presentations of actinotignum (actinobaculum) schaalii infection. | | 2017 | 27810121 |
| actinotignum schaalii subcutaneous abscesses in a patient with hidradenitis suppurativa: case report and literature review. | actinotignum schaalii (formerly actinobaculum schaalii) is a gram-positive, facultative anaerobic rod that is typically involved in urinary tract infections in elderly patients or those with underlying urological pathologies. in contrast, abscess formation caused by a. schaalii is very rare. we present a case of multiple abscesses in the perineal area in a young patient with hidradenitis suppurativa associated with a. schaalii and prevotella melaninogenica and review the relevant literature on t ... | 2017 | 27913316 |
| recurrent obstructive acute pyelonephritis: a rare form of actinotignum (actinobaculum) schaalii infection in a hiv-1 infected patient. | actinobaculum schaalii is a rarely reported, anaerobic, gram-positive bacterium which role as uropathogen is emerging. we report here the case of a 47 year old hiv-1 infected woman presented with five recurrent episodes of obstructive pyelonephritis in the context of multiple renal stones. no bacteria was found until the fifth episode, during which prolonged urinary cultures as well as 16s rdna sequencing allowed the diagnosis of a. schaalii infection. she had developed a life-threatening condit ... | 2017 | 27940245 |
| dissection of the genus actinobaculum: reclassification of actinobaculum schaalii lawson et al. 1997 and actinobaculum urinale hall et al. 2003 as actinotignum schaalii gen. nov., comb. nov. and actinotignum urinale comb. nov., description of actinotignum sanguinis sp. nov. and emended descriptions of the genus actinobaculum and actinobaculum suis; and re-examination of the culture deposited as actinobaculum massiliense ccug 47753t ( = dsm 19118t), revealing that it does not represent a strain of this species. | the remarkable host specificity of the species of the genus actinobaculum led us to recharacterize these species by a polyphasic approach. a comparative chemotaxonomic study including analysis of whole-cell sugars, amino acid composition of the peptidoglycan, fatty acid methyl esters, respiratory quinones and polar lipids revealed significant differences that, in combination with molecular data, support a dissection of the genus actinobaculum. the proposals of this study include the reclassifica ... | 2015 | 25406238 |
| actinobaculum schaalii: identification with maldi-tof. | actinobaculum schaalii is an emerging uropathogen. so far, its identification has been performed with 16s rrna gene sequencing or pcr. the diagnosis has often been delayed due to fastidious growth and identification problems. eleven clinical isolates of a. schaalii from bloodstream infections that were initially identified with 16s rrna sequencing analysis were recovered and later identified with matrix-assisted laser desorption/ionization time-of-flight (maldi-tof). we present a review of bacte ... | 2014 | 25356339 |
| actinobaculum schaalii: a truly emerging pathogen?: actinobaculum schaalii: un pathogène réellement émergent? | actinobaculum schaalii is a gram-positive facultative anaerobe bacillus. it is a commensal organism of the genitourinary tract. its morphology is nonspecific. aerobic culture is tedious, and identification techniques have long been inadequate. thus, a. schaalii has often been considered as a nonpathogen bacterium or a contaminant. its pathogenicity is now well described in urinary tract infections, and infections in other sites have been reported. this pathogen is considered as an emerging one f ... | 2016 | 27014462 |
| actinomyces and related organisms in human infections. | actinomyces israelii has long been recognized as a causative agent of actinomycosis. during the past 3 decades, a large number of novel actinomyces species have been described. their detection and identification in clinical microbiology laboratories and recognition as pathogens in clinical settings can be challenging. with the introduction of advanced molecular methods, knowledge about their clinical relevance is gradually increasing, and the spectrum of diseases associated with actinomyces and ... | 2015 | 25788515 |
| actinobaculum schaalii, a cause of urinary tract infections in children? | aim: to inform that actinobaculum schaalii can colonize the urine and cause urinary tract infection in children. methods: urine samples were examined by wet smear microscopy, incubated in 5% co(2) for 1-2 days, and species-specific real-time polymerase chain reaction (pcr) for a. schaalii was performed. results: in 5 of the 29 screened urines, a. schaalii was found only by real-time pcr in quantities equivalent to ≥10(4) -10(5) cfu/ml. in addition, a. schaalii was found in quantities equiva ... | 2011 | 22211919 |
| actinobaculum schaalii - invasive pathogen or innocent bystander? a retrospective observational study. | abstract: | 2011 | 22029906 |
| actinobaculum schaalii: review of an emerging uropathogen. | actinobaculum schaalii is a facultative anaerobic, gram-positive rod-shaped species phylogenetically related to actinomyces that is likely part of the commensal flora of the human genitourinary tract. because of its fastidious growth under aerobic conditions and its resemblance to bacteria of the resident flora, a. schaalii is frequently overlooked or considered as a contaminant. it is also difficult to identify phenotypically, still requiring molecular identification. note that the recent techn ... | 2011 | 22209960 |
| actinobaculum schaalii, a commensal of the urogenital area. | what's known on the subject? and what does the study add?: actinobaculum schaalii is considered to be a part of the normai flora in the genital and urinary tract area. it has been associated to urinary tract infection (uti), sepsis, osteomyelitis, endocarditis and foumier's gangrene. so far it has mainly been isolated from urine, blood and pus, and predominantly in elderly patients. this study examined the habitat of a. schaalii by collecting samples from skin and urine in patients with kidney o ... | 2013 | 23350855 |
| actinobaculum schaalii causing fournier's gangrene. | actinobaculum schaalii, which belongs to the group of gram-positive rods, is difficult to culture. using molecular genetics, actinobaculum schaalii could be identified as a causing microorganism in a case of fournier's gangrene. | 2011 | 21508151 |
| actinobaculum schaalii pyelonephritis in a kidney allograft recipient. | we present a case of a 64-year-old man, a kidney transplant recipient with acute pyelonephritis and acute graft deterioration. he was diagnosed with actinobaculum schaalii infection in urine cultures. he was treated with antibiotics for 3 weeks and recovered well. the case describes an unusual pathogenic infection in a kidney transplant patient. | 2012 | 22976266 |