| effects of chronic triclosan exposure upon the antimicrobial susceptibility of 40 ex-situ environmental and human isolates. | triclosan (tcs) exposure of escherichia coli selects for tolerant clones, mutated in their enoyl-acyl carrier protein reductase (fabi). it has been inferred that this phenomenon is widespread amongst bacterial genera and might be associated with resistance to third party agents. | 2006 | 16630014 |
| hepatoprotective effect of arazyme on ccl4-induced acute hepatic injury in smp30 knock-out mice. | arazyme is a novel protease produced by the hy-3 strain of aranicola proteolyticus, which is a gram-negative aerobic bacterium that has been isolated from the intestine of the spider nephila clavata. this study focused on the hepatoprotective effect of arazyme on carbon tetrachloride (ccl4)-induced acute hepatic injury in senescence marker protein 30 (smp30) knock-out (ko) mice and smp30 wild-type (wt) mice. wt mice and smp30 ko mice were divided into eight groups as follows: (i) two negative co ... | 2008 | 18308447 |
| endophytic bacteria from pinellia ternata, a new source of purine alkaloids and bacterial manure. | pinellia ternata (thunb.) berit., a perennial herb belonging to araceae, is one of the few medicinal plants to produce purine alkaloids. it is speculated that endophytic bacteria from p. ternata may produce guanosine or inosine. however, there is no report about endophytic bacteria in p. ternata. | 2015 | 25868618 |
| inhibitory effect of arazyme on the development of atopic dermatitis-like lesions in balb/c and nc/nga mice. | arazyme is a metalloprotease released by aranicola proteolyticus that was shown to inhibit cytokine release in hacat and endothelial cells. however, the regulatory effects of arazyme in atopic dermatitis remain to be fully understood. in the present study, the anti‑inflammatory effects of arazyme in balb/c and nc/nga mice induced with 2,4‑dinitrochlrobenzene (dncb) were investigated. balb/c mice were sensitized with dncb and were subsequently administered arazyme for 4 weeks either orally, dorsa ... | 2015 | 25606969 |
| effect of arazyme on the lipopolysaccharide‑induced inflammatory response in human endothelial cells. | arazyme is a novel extracellular metalloprotease secreted by aranicola proteolyticus. endothelial cells are involved in the pathogenesis of a number of inflammatory diseases, induce uncontrolled cell viability and express various inflammatory mediators, including cytokines, chemokines, adhesion molecules and reactive oxygen species (ros). in the current study, human umbilical vein endothelilal cells (huvecs) were used to investigate the anti‑inflammatory effects of arazyme following lipopolysacc ... | 2014 | 24842222 |