adhesion of human neutrophils to fibronectin is inhibited by comaruman, pectin of marsh cinquefoil comarum palustre l., and by its fragments. | earlier, we detected antiinflammatory action of comaruman, pectin of the marsh cinquefoil comarum palustre l. this effect can be explained by new data concerning inhibition of adhesion of human neutrophils to fibronectin by comaruman and its fragments. the galacturonan backbone fragment of molecular mass >10 kd appears to be the active region of the comaruman macromolecule. comaruman cp (50-200 microg/ml) was found to decrease adhesion of neutrophils stimulated by phorbol 12-myristate 13-acetate ... | 2005 | 15701056 |
antiinflammatory activity of the pectic polysaccharide from comarum palustre. | a pectic polysaccharide named comaruman (cp) was extracted from the aerial part of comarum palustre with 0.7% aqueous ammonium oxalate and subsequent precipitation with ethanol. oral administration of comaruman (5-100 mg/kg) was found to reduce a paw edema observed 24 h after injection of 2% formalin in mice. a fraction of comaruman (cp-h9) exhibited a similar antiinflammatory activity. comaruman, cp deprived of lipid, cp purified by proteins and cp fractions obtained with acidic hydrolysis inhi ... | 2005 | 15885926 |
protective effect of comaruman, a pectin of cinquefoil comarum palustre l., on acetic acid-induced colitis in mice. | the efficacy of comaruman cp, a pectin of marsh cinquefoil comarum palustre l., was investigated using a model of acetic acid-induced colitis in mice. mice were administered comaruman cp orally 2 days prior to rectal injection of 5% acetic acid and examined for colonic damage 24 hr later. colonic inflammation was characterized by macroscopical injury, higher levels of myeloperoxidase activity, enhanced vascular permeability, and diminution of colonic mucus. oral administration of comaruman cp wa ... | 2006 | 16927150 |
antiinflammatory activity of proanthocyanidins of rhizomes with roots of comarum palustre l. | | 2009 | 20170066 |
[nefroprotective influence of the comarum palustre l. on chronic experimental glomerulonephritis]. | course introduction of a cowberry dry extract comarum palustre l. on a background of experimental chronic glomerulonephritis renders expressed nephroprotective influence described by normalization of parameters of a kidneys functional condition, blood lipid spectrum and immune status, reduction of expressiveness of destructive changes in nephrones, inhibition of free-radical processes and increase of organism antioxidative protection. | 2010 | 20731125 |
multilevel spatial structure impacts on the pollination services of comarum palustre (rosaceae). | habitat destruction and fragmentation accelerate pollinator decline, consequently disrupting ecosystem processes such as pollination. to date, the impacts of multilevel spatial structure on pollination services have rarely been addressed. we focused on the effects of population spatial structure on the pollination services of comarum palustre at three levels (i.e. within-population, between-populations and landscape). for three years, we investigated 14 belgian populations, which differed in the ... | 2014 | 24915450 |
agrimoniin, an active ellagitannin from comarum palustre herb with anti-α-glucosidase and antidiabetic potential in streptozotocin-induced diabetic rats. | naturally existing α-glucosidase inhibitors from traditional herbal medicines have attracted considerable interest to treat type 2 diabetes mellitus (dm). the present study aimed to evaluate the anti-α-glucosidase activity of extracts from marsh cinquefoil (comarum palustre l.), their hypoglycaemic action and detection of the responsible compounds. a 60% ethanol extract from c. palustre herb revealed the highest inhibitory activity against α-glucosidase (ic50 52.0 μg/ml). the hplc analysis of th ... | 2017 | 28045450 |
the cryoprotectant effect of polysaccharides from plants and microalgae on human white blood cells. | the use of carbohydrates as cryoprotectants is increasing. in this study the effects of incorporating polysaccharides extracted from plants and microalgae originating in northern russia, into cryoprotectant solutions used to preserve human white blood cells were investigated. cells in the presence of the polysaccharides were cooled to either -40°c or -80°c, using a two-step cooling process. the morphological and functional indicators of the cryopreserved leukocytes were assessed by light microsc ... | 2015 | 26186407 |
influence of spatial distribution and size of clones on the realized outcrossing rate of the marsh cinquefoil (comarum palustre). | clonal growth is a common feature in flowering plants. as clone size increases, the selfing rate in self-compatible species is likely to increase due to more frequent geitono-pollination events (i.e. pollination among flowers within the same genet). this study investigated the breeding system of the marsh cinquefoil (comarum palustre) and assessed spatial distribution of clones, clone size and architecture, and their effects on realized outcrossing rates. in addition, pollen dispersal was invest ... | 2014 | 24284813 |
development and multiplexing of microsatellite markers using pyrosequencing in the clonal plant comarum palustre (rosaceae). | microsatellites represent one of the most commonly used genetic markers for population genetic studies. traditionally, their development is quite time consuming, requiring construction of a genomic library enriched for repeated motifs. using pyrosequencing, a fast and cost-effective new generation sequencing technique, we produced 24,340,862 bases in 63,860 short fragment reads, including 1170 dinucleotide motifs with a minimum of six repeats and 1383 trinucleotide motifs with a minimum of four ... | 2012 | 21951679 |
a new source of proanthocyanidins with antiarthritic activity: purple marshlocks (comarum palustre l.) rhizome and roots. | | 2008 | 18853774 |
branching of the galacturonan backbone of comaruman, a pectin from the marsh cinquefoil comarum palustre l. | galacturonan, the main constituent of the backbone (core) of the comaruman macromolecule, a pectin from the marsh cinquefoil comarum palustre l., was obtained on partial acid hydrolysis of the pectin. using atomic force microscopy and methylation analysis of the galacturonan, the backbone of the comaruman macromolecule was shown to contain branches as side chains consisting of alpha-1,4-linked residues of d-galactopyranosyl uronic acid attached to the 2- and 3-positions of the galacturonic acid ... | 2006 | 16732733 |
structural studies on pectin from marsh cinquefoil comarum palustre l. | pectin with [alpha]d(20) +192 degrees (c 0.1; water), named comaruman, was isolated from marsh cinquefoil comarum palustre l., which is widespread in the european north. the sugar chain of comaruman contains residues of d-galacturonic acid (64%), d-galactose (13%), l-rhamnose (12%), l-arabinose (6%), and trace amounts of xylose and glucose. partial acid hydrolysis and digestion with pectinase demonstrated that comaruman composed of the backbone comprised regions of linear alpha-1,4-d-galactopyra ... | 2005 | 16212542 |
[study of tannins in comarum palustre l., a bound form of tannin]. | | 2009 | 14316129 |
[study of the ethereal oil of comarum palustre l]. | | 2009 | 14082755 |
[pharmacological studies on comarum palustre]. | | 2009 | 14037221 |