| fusarium merismoides corda nr 6356, the source of the protein kinase c inhibitor, azepinostatin. taxonomy, yield improvement, fermentation and biological activity. | fungal strain nr 6356, fusarium merismoides corda, was discovered as the source of the protein kinase c (pkc) inhibitor, azepinostatin. the strain was identified based on its growth on potato sucrose agar, slender conidial shape, characteristic polyphialide and production of abundant chlamydospores. fusarium aquaeductuum lagh. imi 103658 and fusarium sp. nr 7222 were also found to produce the same inhibitor. after single colony isolation and medium optimization trials, a more than 30-fold increa ... | 1994 | 8040068 |
| filamentous fungi associated with mosquito larvae (diptera: culicidae) in municipalities of the brazilian amazon. | several species of the family culicidae are important vectors of diseases in humans and other animals. immature stages are filter-feeders of organic particulate matter and microorganisms. studies on microbial diversity can contribute to the discovery of new substances that can be used in the pharmaceutical industry for food or for biological control. the aim of this study was to isolate and identify the fungi associated with culicidae larvae found in different habitats (natural and artificial), ... | 2009 | 19618051 |
| isolation, identification and antimicrobial activity of propolis-associated fungi. | propolis is a natural product widely known for its medicinal properties. in this work, fungi present on propolis samples were isolated, identified and tested for the production of antimicrobial metabolites. twenty-two fungal isolates were obtained, some of which were identified as alternaria alternata, aspergillus flavus, bipolaris hawaiiensis, fusarium merismoides, lasiodiplodia theobromae, penicillium citrinum, penicillium crustosum, penicillium janthinellum, penicillium purpurogenum, pestalot ... | 2013 | 23439233 |
| deoxycholic acid transformations catalyzed by selected filamentous fungi. | more than 100 filamentous fungi strains, mostly ascomycetes and zygomycetes from different phyla, were screened for the ability to convert deoxycholic acid (dca) to valuable bile acid derivatives. along with 11 molds which fully degraded dca, several strains were revealed capable of producing cholic acid, ursocholic acid, 12-keto-lithocholic acid (12-keto-lca), 3-keto-dca, 15β-hydroxy-dca and 15β-hydroxy-12-oxo-lca as major products from dca. the last metabolite was found to be a new compound. t ... | 2016 | 26718089 |
| purification and characterization of 4-n-trimethylamino-1-butanol dehydrogenase from fusarium merismoides var. acetilereum. | from investigation of 60 filamentous fungi, we identified fusarium merismoides var. acetilereum, which uses 4-n-trimethylamino-1-butanol (tma-butanol) as the sole source of carbon and nitrogen. the fungus produced nad(+)-dependent tma-butanol dehydrogenase (dh) when it was cultivated in medium containing tma-butanol. the enzyme showed molecular mass of 40 kda by sds-page and 160 kda by gel filtration, suggesting that it is a homotetramer. tma-butanol dh is stable at ph 7.5-9.0. it exhibits moder ... | 2016 | 27121905 |
| genetic variation in fusarium merismoides preserved by two different methods. | restriction-enzyme digestion followed by agarose gel electrophoresis demonstrated differences between the purified dna from fusarium merismoides which had been held in a culture collection in liquid n2 and that from soil-stored samples of the same fungus. extended incubation (3 to 4 weeks) of a culture resulted in the appearance of an extra band, sensitive to ecori, which could correspond to a previously reported plasmid and may, therefore, be associated with senescence. the results emphasize th ... | 1995 | 24414657 |