| [the course of trypanosoma cruzi infection in nonsplenectomized spe rats with and without haemobartonella muris infection (author's transl)]. | rats were infected with h. muris from the first to the second week of their life. four weeks later 20 of the infected rats were inoculated with 1.5 x 10(5) t. cruzi. control animals were given the same number of parasites. in both experimental groups no hemoflagellate could be seen in blood smears four weeks after infection. the comparison of the course of infection of t. cruzi in rats with and without h. muris was made using t- and wilcoxon-test for pair differences. rats with h. muris infectio ... | 1977 | 414392 |
| [latex-chagestest-reactions of immunsera against bartonella bacilliformis, haemobartonella muris and eperythrozoon coccoides (author's transl)]. | sera from 10 patients positive for carrion's disease were analysed by means of the latex chagas test. sera from 40 spf-rats experimentally infected with haemobartonella muris and 5 spf-mice experimentally infected with eperythrozoon coccoides were similarly tested. both the human and mice sera were negative whereas positive reaction was observed with rat sera. the nature of this positive reaction has not been clarified. | 1977 | 888185 |
| autoimmune factors associated with anaemia in acute haemobartonella and eperythrozoon infections of rodents. | eperythrozoon coccoides and haemobartonella muris produced in mice and rats respectively, essentially the same disease, characterized by anaemia, splenomegaly and in severe cases, haemoglobinuria with death. in both infections anaemia was associated with phagocytosis of erythrocytes by monocytes of the spleen, and with the presence of cold-active haema-glutinin for trypsinized red cells (cah). an antigen similar to the serum antigen (sa) associated with acute malaria and babesiosis was also foun ... | 1976 | 946746 |
| [immunobiology of tuberculosis]. | r. koch showed in 1882 in his so-called fundamental experiment that tuberculous guinea pigs exhibit a vigorous immunity against re-infection. in investigations in 1930--40 we showed that this immunity is not mediated by humoral antibodies. it is a cellular process, a local and general activation of the macrophage system (the system of mononuclear phagocytes). the tuberculous granuloma consists of activated macrophages and their descendants (epitheloid and giant cells), which inhibit the growth a ... | 1976 | 1085918 |
| latent haemobartonella muris infection: its transmission and decline in an inbred, ectoparasite-free strain of wistar rat. | ectoparasite-free, spf italian wistar rats were consistently found to carry a latent infection with haemobartonella muris, activable by splenectomy. in an inbred line this diminished and eventually ceased in six generations. experimental infection from wild rats demonstrated that this was not apparently due to immunity. | 1975 | 1242217 |
| the effects of tumours in suppressing haemobartonella muris in splenectomized rats. | | 1974 | 4480650 |
| [formation of heinz bodies in presence of haemobartonella muris: inhibition by peroxidase]. | | 1967 | 5611976 |
| [multiplication in vitro of haemobartonella muris and h. canis]. | | 1967 | 5611977 |
| phagocytosis and anemia in rats infected with haemobartonella muris. | | 1968 | 5668034 |
| [arginine-deiminasic activity of haemobartonella muris]. | | 1968 | 5674887 |
| the relationship of parasitemia to the life span of erythrocytes of rats infected with haemobartonella muris. | | 1968 | 5701288 |
| identity of the filterable hemolytic anemia agent of sacks with haemobartonella muris. | moore, d. h. (the rockefeller university, new york, n. y.), r. n. arison, h. tanaka, w. t. hall, and m. chanowitz. identity of the filterable hemolytic anemia agent of sacks with haemobartonella muris. j. bacteriol. 90:1669-1674. 1965.-in 1960 a new hemolytic agent in rats was reported. it was thought to be a filterable, nonsedimentable, replicating infectious agent, different from haemobartonella muris. rats which recovered from the infection developed a resistance to several kinds of transplan ... | 1965 | 5854589 |
| fine structure of haemobartonella muris as compared with eperythrozoon coccoides and mycoplasma pulmonis. | tanaka, h. (the rockefeller university, new york, n.y.), w. t. hall, j. b. sheffield, and d. h. moore. fine structure of haemobartonella muris as compared with eperythrozoon coccoides and mycoplasma pulmonis. j. bacteriol. 90:1735-1749. 1965.-thin sections of filterable hemolytic anemia agent of rat, now identified as haemobartonella muris, revealed (i) that the agent is spherical or ellipsoidal and 350 to 700 mmu in size, (ii) that it has a single limiting membrane enclosing granules and some f ... | 1965 | 5854594 |
| [action of antibiotics and chemotherapeutic agents on haemobartonella muris infections]. | | 1966 | 5971361 |
| haemolytic anaemia in the gunn rat following transplantation of isolated hepatocytes injected with haemobartonella muris. | extensively purified preparations of isolated rat hepatocytes derived from wistar rats infected with haemobartonella muris induced haemolytic anaemia when injected into congenitally jaundiced gunn rats. in the absence of overt parasitaemia and marked falls in haematocrit, elevation of total plasma bilirubin levels was a valuable indicator of red-cell destruction. evidence is presented that the parasite is removed by the spleen from the surface of infected red cells which then remain in the circu ... | 1981 | 7013779 |
| haemobartonella muris: case report and investigation of transplacental transmission. | | 1982 | 7062707 |
| immunoconglutinin and antibody against fibrinogen products in hemolytic anemia and nephritis resulting from infection with a haemobartonella-like agent. | an agent morphologically similar to haemobartonella muris was isolated from the blood of rats infected with a strain of trypanosoma lewisi kept at this department. it caused acute hemolytic anemia, splenomegaly, glomerulonephritis, and death within 5 to 8 days in mature sprague-dawley rats. the disease was less severe in weanling rats which usually recovered within 3 to 4 wk. the anemia was accompanied by phagocytosis of erythrocytes by monocytes of the spleen and bone marrow, by high titers of ... | 1981 | 7264835 |
| western immunoblot analysis of haemobartonella muris and comparison of 16s rrna gene sequences of h. muris, h. felis, and eperythrozoon suis. | infectious agents were isolated from the spleens of three wild mice (apodemus argenteus) by intraperitoneal inoculation of the spleen homogenate into laboratory mice. the laboratory mice developed clinical signs and splenomegaly, and three isolates were maintained by passage in mice. tetracyclines were effective in preventing infection of mice with these agents, but streptomycin and penicillin were ineffective. the agents did not grow in bacterial growth media or chicken embryos. in smears of bl ... | 1997 | 9157135 |
| proposal to transfer some members of the genera haemobartonella and eperythrozoon to the genus mycoplasma with descriptions of 'candidatus mycoplasma haemofelis', 'candidatus mycoplasma haemomuris', 'candidatus mycoplasma haemosuis' and 'candidatus mycoplasma wenyonii'. | cell-wall-less uncultivated parasitic bacteria that attach to the surface of host erythrocytes currently are classified in the order rickettsiales, family anaplasmataceae, in the genera haemobartonella and eperythrozoon. recently 16s rrna gene sequences have been determined for four of these species: haemobartonella felis and haemobartonella muris and eperythrozoon suis and eperythrozoon wenyonii. phylogenetic analysis of these sequence data shows that these haemotrophic bacteria are closely rel ... | 2001 | 11411711 |
| revision of haemotrophic mycoplasma species names. | the recently proposed transfer of four rickettsias from the genera haemobartonella and eperythrozoon to the genus mycoplasma with the candidatus status is herein revised. this is because the candidatus designation is for new, incompletely described taxa, in order to give them a provisional status. thus, 'candidatus mycoplasma haemofelis' is revised to mycoplasma haemofelis comb. nov., nom. nov., 'candidatus mycoplasma haemomuris' is revised to mycoplasma haemomuris comb. nov., nom. nov., 'candid ... | 2002 | 11931184 |
| evaluation of sensitivity and specificity of a mycoplasma haemomuris-specific polymerase chain reaction test. | mycoplasma haemomuris, a small pleomorphic bacterium parasitic of red blood cells, often causes chronic and subclinical infection of rodents. mycoplasma haemomuris is uncultivable, and a serologic testing method is not readily available. the purpose of the study reported here was to develop a sensitive and specific polymerase chain reaction (pcr) test for detection of m. haemomuris in blood samples. | 2002 | 12211273 |
| characteristics of the 16s-23s rrna intergenic spacer region of mycoplasma haemomuris, previously classified as 'haemobartonella muris'. | the intergenic spacer region between the 16s and 23s rrna genes of mycoplasma haemomuris, previously classified as 'haemobartonella muris', was amplified by pcr and sequenced for analysis of the primary and secondary structures of the rna transcript. the spacer region consisted of 219 base-pairs and lacked the spacer trna gene. a hypothetical secondary structure predicted in the rna transcript of the spacer region was tentatively assigned box a and box b loci peculiar to the members of the mycop ... | 2002 | 12520114 |
| [blood parasites of the white mouse. ii. bartonella muris musculi schilling]. | | 1952 | 13006899 |
| relationship between bartonella muris infection and acute radiation effects in the rat. | | 1954 | 13212130 |
| a complement-fixation reaction with haemobartonella muris and eperythrozoon coccoides. | | 1956 | 13387692 |
| [new studies on haemobartonella muris mayer. iii]. | | 1956 | 13393279 |
| [serological reactions with haemobartonella muris and eperythrozoon coccoides]. | | 1956 | 13393280 |
| cellular factors in the acquired immunity to bartonella muris. | | 1957 | 13463384 |
| [haemobartonella muris as a causative organism of anemia in parabiosis rats]. | | 1958 | 13558477 |
| the mechanism of transmission of haemobartonella muris (mayer) of rats by the spined rat louse, polyplax spinulosa (burmeister). | | 1958 | 13621318 |
| lifespan of rat erythrocytes parasitized by bartonella muris. | | 1959 | 13631283 |
| extrinsic incubation period of haemobartonella muris in the spined rat louse, polyplax spinulosa. | | 1959 | 13641220 |
| activation of bartonella muris infection in x-irradiated rats. | | 1962 | 13867651 |
| [the effect of recent antibiotics on haemobartonella muris and eperythrozoon coccoides]. | | 1964 | 14309969 |
| [stability and preservation of haemobartonella muris]. | | 1965 | 14343727 |
| [attempts of reducing haemobartonella muris and eperythrozoon coccoides]. | | 1954 | 14360361 |
| the effect of x-irradiation on rats with and without bartonella muris. | | 1951 | 14850746 |
| synergistic effect of haemobartonella muris on plasmodium berghei in white rats. | | 1952 | 14952697 |
| [new investigations on bartonella muris mayer. ii..]. | | 1952 | 14959268 |
| experimental anemias in the rat; i. macrocytic anemia in chronic pteroylglutamic acid deficiency and after splenectomy in bartonella muris infection. | | 1950 | 15414205 |
| a non-pathogenic bartonella-like organism developing in embryonate eggs after injection with haemobartonella muris. | | 1950 | 15428634 |
| anemia in rats infested with bartonella muris and injected with pteroylglutamic acid. | | 1948 | 18907621 |
| [not available]. | | 1947 | 18919319 |
| etiology of oroya fever : xi. comparison of bartonella bacilliformis and bartonella muris. cultivation of bacterium murium, n. sp. | bartonella muris appeared in the blood of all white rats, wild rats, chinese hamster, and mice, from which the spleen was removed, but did not appear in that of splenectomized monkeys, rabbits, or guinea pigs. it has not been possible to transmit b. muris to normal rats, monkeys, rabbits, or guinea pigs, by intraperitoneal, intradermal, or intravenous injection of blood containing b. muris from splenectomized rats. in two instances an acute orchitis was induced in normal rats by injection direct ... | 1928 | 19869409 |
| the transfer of rat anemia to normal animals. | fifty-eight white and hooded rats have been splenectomized and all of them have shown a more or less severe anemia and an infection of the red blood cells with bartonella muris. another strain of white rats obtained from littlestown showed no anemia and no bartonellas in the blood after splenectomy, until exposed to infected rats. others of these littlestown rats, kept in the laboratory for some time before operation and exposed to infected rats, came down with bartonella anemia within 6 days af ... | 1928 | 19869499 |
| studies on bartonella muris anemia of albino rats : i. trypanosoma lewisi infection in normal albino rats associated with bartonella muris anemia ii. latent infection in adult normal rats. | 1. the virus of bartonella muris anemia of splenectomized rats may be transmitted to normal young unoperated rats and rabbits. this confirms the observations of ford and eliot. 2. trypanosoma lewisi infections in normal adult rats are accompanied by an anemia most marked at the height of the infection and the appearance of bartonella muris bodies in the red blood cells. 3. in young rats trypanosoma lewisi may produce death from the severity of the anemia, complicating the disease. the anemic vir ... | 1930 | 19869745 |
| studies on bartonella muris anemia of albino rats : iii. the protective effect of autoplastic splenic transplants on the bartonella muris anemia of splenectomized rats. | autoplastic splenic transplants were made in adult albino rats 4 weeks and 7 weeks prior to splenectomy and the protective effects against infection with the bartonella muris anemia observed. 1. one-fourth of the spleen left in situ will protect adult albino rats against the bartonella muris anemia. 2. autotransplantation of splenic tissue in adult rats is successful in over 90 per cent of instances. 3. autoplastic splenic transplants performed 7 weeks prior to splenectomy afford protection agai ... | 1930 | 19869746 |
| further studies on t. lewisi infection in albino rats : i. the effect of splenectomy on t. lewisi infection in albino rats and the protective action of splenic autotransplants ii. the effect of thymectomy and bilateral gonadectomy on t. lewisi infection in albino rats. | t. lewisi infection in normal adult 3 month old albino rats raised from a single stock and maintained under identical conditions was studied. daily quantitative estimates of the trypanosomes in the circulating blood were made and the course of the infection was studied. bilateral suprarenalectomy in rats lowers the resistance to a subsequent infection with t. lewisi. about 70 per cent of these rats die in an average period of 5.8 days after injection. the multiplication of the parasites, in the ... | 1930 | 19869791 |
| compensatory hypertrophy of the spleen. | following the removal of half of the spleen in young adult rats there is a compensatory enlargement of the remaining portion of about 50 per cent while in mature rabbits no such compensatory hypertrophy follows a similar procedure. it is uncertain whether this difference is due to a difference in the function of the spleen in the two species or to the fact that the rats were infected with bartonella muris while the rabbits were not. | 1931 | 19869845 |
| studies on bartonella muris anemia : iv. pathological changes during the acute anemia. | the pathological changes that follow a severe infection with bartonella muris in the adult or young albino rat are: first, those that result from the release of large quantities of cellular debris in the circulating blood. there is phagocytic activity and hyperplasia of the endothelial elements of the liver, thymus, lymph nodes and, in the young rat, of these elements in the spleen, with resultant capillary thromboses and focal necroses. second, changes result from the anemia as such-fatty metam ... | 1931 | 19869889 |
| studies on bartonella muris anemia : v. compensatory phenomena following splenectomy in the adult albino rat. | in bartonella muris carrier stock certain changes are observed in the lymphoblastic and reticular and endothelial elements after splenectomy and recovery from the anemia. these changes appear 3 to 5 months after splenectomy and are associated with immunity to further infection with bartonella muris. the changes consist primarily of hyperplasia of hemolymph tissue, hyperplasia of reticular and endothelial elements of lymph nodes, the formation of lymphoblastic foci periportally in the liver and p ... | 1931 | 19869890 |
| the effect of bilateral suprarenalectomy in adult albino rats on the natural and acquired resistance to bartonella muris anemia. | normal adult wistar rats (non-carrier stock) are readily infected with bartonella muris and develop a severe anemia if large amounts of infecting material are used. the normal adult rat of wistar stock possesses a relatively high natural resistance to spontaneous infection with this organism. bilateral suprarenalectomy in wistar rats lowers the natural resistance to a subsequent infection with bartonella muris. this procedure does not alter the type of tissue response to the virus but lowers the ... | 1932 | 19869970 |
| the etiology of bartonella muris anemia of the albino rat : the isolation of bartonella muris. | 1. bartonella muris has been isolated in pure culture on noguchi's leptospira medium from the blood of the splenectomized adult rat suffering with bartonella muris anemia. 2. bartonella muris is a small, actively motile, gram-negative bacillus. it grows best on media containing blood and on noguchi's leptospira medium. the optimal temperature for growth is 20-25 degrees c. it produces neither gas nor acid on media containing sugars. it does not hemolyze blood in artificial media. viability of th ... | 1932 | 19870100 |
| studies on bartonella muris anemia : vi. a lipoid extract of the spleen that prevents bartonella muris anemia in splenectomized albino rats. | an aqueous lipoid extract of ox spleen was prepared which protects adult male albino rats of carrier stock in a large percentage of instances against bartonella muris anemia following splenectomy. it is suggested that the extract contains a specific hormonal substance. | 1932 | 19870101 |
| studies on bartonella muris anemia : vii. the protective action of copper and iron against bartonella muris anemia. | the effect on bartonella muris anemia of adding copper or iron or both to an adequate diet was studied. the addition to the diet of copper (0.1 mg. per rat per day), or iron (1 mg. per day), or both during a period of 2 days prior to splenectomy and 1 month subsequent thereto failed to protect adult albino rats against bartonella muris anemia. the addition of copper to an adequate diet for a period of 10 days prior to splenectomy and 1 month subsequent thereto protected 75 per cent of the rats a ... | 1932 | 19870102 |
| studies on bartonella muris anemia : viii. changes in the chemical constituents of the blood during the anemia. | 1. the blood chemistry of normal adult rats and of splenectomized adult rats suffering with bartonella muris anemia has been studied. 2. non-protein nitrogen rises with the increase in severity of the anemia. total serum proteins, serum albumin and serum globulin decrease slightly. uric acid remains unchanged. 3. serum chloride concentration remains unchanged, but the concentration of chlorides in the blood increases. 4. an acidosis as estimated by the carbon dioxide-combining capacity of the bl ... | 1933 | 19870123 |
| the metabolism of copper and iron in splenectomized rats free from bartonella muris infection. | removal of the spleen in albino rats free from bartonella muris infection is followed by an increased elimination of copper in the feces, which commences 2 weeks after splenectomy. this is associated with a persistent negative copper balance. an increased retention of iron occurs during a period of 4 to 6 weeks after splenectomy with a return of the iron metabolism to normal after this period. no disturbance in creatine or creatinine metabolism occurs. the uric acid amount is unchanged. there is ... | 1934 | 19870310 |
| the association of bartonella bodies with induced anemia in the dog. | on feeding to splenectomized dogs a diet producing black tongue, severe anemia developed associated with the presence of small bodies in or on the erythrocytes. the bodies were morphologically similar to bartonella muris and bartonella canis. the addition of lean beef to the diet, a material prophylactic against its effects, was followed by improvement of the blood levels, the presence of increased numbers of reticulocytes in the circulating blood, and the disappearance of the bodies. when the b ... | 1935 | 19870342 |
| the reticulo-endothelial system and hormone refractoriness. | 1. young splenectomized female rats, free of latent infection, show greater increases in ovarian weight in response to injections of pregnant mare's serum than do young normal rats with spleens intact. 2. the regression in ovarian weight which occurs after about a month in such injected splenectomized animals may be prevented by repeated injections of an agent like trypan blue which causes blockage of the compensating reticulo-endothelial elements. 3. the plasmas obtained from these splenectomiz ... | 1939 | 19870913 |
| discussion on the pathology and treatment of haemopathies, including leukaemias, of man and animals: the haemopathies of laboratory animals. | the difference between haemopathies (which originate in the blood-forming tissues) and blood-diseases (which develop in the blood-stream) is explained and illustrated by examples and specimens.primary anaemia caused by the hyperplasia of the erythroblastic tissues in the marrow occurs in fowls as erythromyelosis. this condition can be experimentally transmitted, though inoculation in fowls may reproduce the anaemic disease, or give rise to a persistent polyerythrocythaemia. on farms erythromyelo ... | 1931 | 19988216 |
| the bartonella and related parasites in man and animals (oroya fever and verruga peruviana): (section of tropical diseases and parasitology). | through the investigations of noguchi on the one hand, and mayer and kikuth on the other, the unity of the aetiology of oroya fever and verruga peruviana has been demonstrated experimentally. the bartonella bacilliformis, the causal organism of oroya fever, belongs to a group of micro-organisms, the parasitic nature of which has been definitely proved during the last few years. tests with a view to transmitting the disease to monkeys, and the aetiology, clinical data, pathology, therapy and immu ... | 1934 | 19989875 |
| reticulo-endothelial immune serum (reis); an experimental anemia in bartonella infected rats produced by anti-blood immune serum. | | 1947 | 20292837 |
| discussion on the pathology and treatment of hæmopathies, including leukæmias, of man and animals: the hæmopathies of laboratory animals. | the difference between hæmopathies (which originate in the blood-forming tissues) and blood-diseases (which develop in the blood-stream) is explained and illustrated by examples and specimens.primary anæmia caused by the hyperplasia of the erythroblastic tissues in the marrow occurs in fowls as erythromyelosis. this condition can be experimentally transmitted, though inoculation in fowls may reproduce the anæmic disease, or give rise to a persistent polyerythrocythæmia. on farms erythromyelosis ... | 1931 | 20912613 |
| molecular characterization and phylogenetic analysis of the causative agent of hemoplasma infection in small indian mongoose (herpestes javanicus). | hemoplasmas are the trivial name for a group of erythrocyte-parasitizing bacteria of the genus mycoplasma. this study is the first report of hemoplasma infection in small indian mongoose (herpestes javanicus) based on molecular analysis of 16s rdna. whole blood samples were collected by sterile methods, from 14 live captured mongooses, in the south of iran. candidatus mycoplasma turicensis (cmt)-like hemoplasma was detected in blood samples from one animal tested. blast search and phylogenetic a ... | 2014 | 25097036 |
| occurrence and molecular characterization of hemoplasmas in domestic dogs and wild mammals in a brazilian wetland. | hemotropic mycoplasmas are known to cause anemia in several mammalian species. the present work aimed to investigate the occurrence of mycoplasma spp. in wild mammals, domestic dogs and their respective ectoparasites, in southern pantanal region, central-western brazil. between august 2013 and march 2015, 31 nasua nasua, 78 cerdocyon thous, seven leopardus pardalis, 42 dogs, 110 wild rodents, and 30 marsupials were trapped and ectoparasites (ticks and fleas) found parasitizing the animals were c ... | 2017 | 28366511 |
| proposal for 'candidatus mycoplasma haemomuris subsp. musculi' in mice, and 'candidatus mycoplasma haemomuris subsp. ratti' in rats. | mycoplasma haemomuris is causative of infectious anaemia or splenomegaly in rodents. we examined the nucleotide sequences of the non-ribosomal genes, rnpb and dnak, in strains of the species m. haemomuris detected in small field mice and black rats. rnpb nucleotide sequences in strains of the species m. haemomuris isolated from small field mice and black rats had only 89 % sequence similarity, suggesting their separation into two distinct subgroups. dnak had a nucleotide sequence similarity of 8 ... | 2015 | 25406232 |
| hemotropic mycoplasmas in little brown bats (myotis lucifugus). | hemotropic mycoplasmas are epicellular erythrocytic bacteria that can cause infectious anemia in some mammalian species. worldwide, hemotropic mycoplasmas are emerging or re-emerging zoonotic pathogens potentially causing serious and significant health problems in wildlife. the objective of this study was to determine the molecular prevalence of hemotropic mycoplasma species in little brown bats (myotis lucifugus) with and without pseudogymnoascus (geomyces) destrucans, the causative agent of wh ... | 2014 | 24655520 |
| molecular detection of mycoplasma haemomuris subspecies using dnak-targeted real-time pcr with sybr green i and melting curve analysis. | hemoplasmas cause severe infections in mammals, but these pathogens are difficult to detect and identify at the species and subspecies level because of the need for time-consuming sequence based methods. here, we used real-time pcr with sybr green i targeting of the dnak gene followed by standard melting curve analysis to achieve rapid detection and differentiation of the mycoplasma haemomuris subspecies 'candidatus mycoplasma haemomuris subsp. musculi' and 'candidatus m. haemomuris subsp. ratti ... | 2016 | 27720908 |
| two clusters among mycoplasma haemomuris strains, defined by the 16s-23s rrna intergenic transcribed spacer sequences. | mycoplasma haemomuris is a causative organism of infectious anemia or splenomegaly in rodents. here, we report two distinct genetic groups among m. haemomuris strains detected from rats and mice, respectively, by examining the nucleotide sequences of the 16s-23s rrna intergenic transcribed spacer region that has been shown to be a stable genetic marker for mycoplasma species. our results may reveal host-tropism of each cluster of m. haemomuris strains, and suggest an idea to distinguish m. haemo ... | 2013 | 23238428 |