| cytopathology of nipple discharge due to pityrosporum orbiculare and cocci in an elderly woman. | a case has been described where cytologic examination first showed a fungus infection as the possible cause of a nipple discharge of long duration. the discharge was found to be associated with pityrosporum orbiculare, micrococcus tetragenes and staphylococci (coagulase negative). administration of an antibiotic that inhibited the bacteria cured the condition. | 1975 | 46660 |
| the activity in vitro of five different antimycotics against pityrosporum orbiculare. | the activity in vitro of miconazole, clotrimazole, econazole, sodium omadine, and sodium thiosulphate against pityrosporum orbiculare was found to correlate with the good clinical results these drugs produce in tinea versicolor. in addition many substances used as solvents or in vehicles had an inhibitory effect in vitro against p. orbiculare. the influence of the culture medium, especially lipids, on the action of imidazole derivatives is discussed. | 1979 | 94211 |
| cell-mediated immunity to pityrosporum orbiculare in tinea versicolor. | pityrosporum orbiculare, the presumed etiologic agent of tinea versicolor, was cultured in vitro and antigenic extracts prepared from the cultured organisms. studies with lymphocytes from human cord blood and peripheral blood of guinea pigs demonstrated that such extracts were not mitogenic. further studies in guinea pigs indicated that the animals could be sensitized by the injection of p. orbiculare extract in freund's complete adjuvant and that this extract could elicit lymphocyte transformat ... | 1978 | 96143 |
| [saphrophytic life of opportunistic fungi]. | probably all pathogenic fungi can cause opportunistic infections in compromised hosts. this paper briefly reviews our knowledge on the saprophytic life - geographic distribution and habitat - of the most common pathogenic fungi. some mycoses are of endogenous origin - e.g. candida albicans is an endosaprophyte - others of epigenon origin - e.g. pityrosporum ovale is an episaprophyte - but most mycoses are caused by fungi which have an exosaprophytic (or exosaprobic) life: one becomes infected af ... | 1979 | 114433 |
| immunological studies on pityrosporum genus and malassezia furfur. | the antigenicity of malassezia furfur from patients with tinea versicolor and 3 species of pityrosporum was investigated using the antiserum against p. orbiculare. the ouchterlony gel diffusion test revealed a considerable similarity between the antigenicities of p. orbiculare and p. ovale, and little similarity between p. orbiculare andp. canis. similar results were obtained by immunofluorescence staining with the fitc-labeled p. orbiculare antiserum. hyphae and round spores of m. furfur in the ... | 1979 | 115927 |
| [pityrosporum orbiculare in acneiform eruptions]. | six patients with acneiform eruptions in the predilection sites of pityriasis versicolor are briefly described. histologically there were abscesses below the acroinfundibulum wherein yeasts could be found with the characteristics of pityrosporum orbiculare. the possible pathogenity of these fungi is discussed. | 1977 | 143463 |
| ultrastructural basis for the assay of topical acne treatments. transmission and scanning electron microscopy of untreated comedones. | after two decades of using systemic antibiotics as a main treatment for acne, emphasis is again being placed on topical agents. thus, it is highly desirable to have a procedure whereby the activity of the various compounds can be evaluated by direct visualization. scanning electron microscopy combined with transmission electron microscopy provide the tools for such in assay. this study describes the ultrastructure of untreated comedones and provides the baseline or control data necessary for tes ... | 1978 | 151693 |
| tinea versicolor and pityrosporum orbiculare: a mycological investigation. | | 1979 | 161078 |
| quantitative microbiology of the scalp in non-dandruff, dandruff, and seborrheic dermatitis. | the composition of the scalp microflora was assessed quantitatively in normal individuals and in patients with dandruff and seborrheic dermatitis, disorders characterized by increasing scaling. three organisms were constantly found: (1) pityrosporum, (2) aerobic cocci, and (3) corynebacterium acnes. pityrosporum (mainly pityrosporum ovale) made up 46% of the total microflora in normals, 74% in dandruff, and 83% in seborvheic dermatitis. the geometric mean number of organisms per cm-2 in non-dand ... | 1975 | 237965 |
| confluent and reticulated papillomatosis (gougerot-carteaud). | seven cases, one female and six males with confluent and reticulated papillomatosis are presented. age range was 13-25 years and the skin disease had lasted for 6 months to 3 years. initially, acanthosis nigricans was suspected in all cases as the skin histology was compatible with that diagnosis. pityrosporum orbiculare was cultured in 4 cases, but treatment with selenium sulfide and miconazole was unsuccessfull. no endocrinological abnormities were revealed. only associated feature was a marke ... | 1979 | 294095 |
| morphological and cultural aspects of pityrosporum (malassezia) furfur. | | 1978 | 299470 |
| in vitro and in vivo ultrastructural changes in pityrosporum orbiculare after treatment with econazole. | | 1978 | 299492 |
| tinea versicolor and pityrosporum orbiculare: mycological investigations, experimental infections and epidemiological surveys. | in patients with tinea versicolor, pityrosporum orbiculare was cultured from tinea versicolor lesions in 100%, from normal-looking skin in 80%, and from apparently healed lesions in 69%. p. orbiculare was isolated from normal skin in 85% of patients with seborrheic dermatitis and in 90% of volunteers. the best substrate for isolation of p. orbiculare was a peptone-glucose-yeast extract medium containing glycerol monostearate and tween 80, overlaid with olive oil. germ tubes were produced when p. ... | 1979 | 390959 |
| superficial mycoses in a southern new zealand district. | a total of 2,709 pathogenic fungi were isolated from 8,762 patients suspected as having mycotic disease, over an 8 year period in christchurch, new zealand. the district is climatically designated as temperate with average mean temperatures of 17 degrees c in summer and 8 degrees c in winter. the predominant species of fungi were relatively small in number with trichophyton mentagrophytes var. interdigitals as the major pathogen. fungi other than true dermatophytes, particularly candida spp. and ... | 1979 | 396678 |
| experimental tinea versicolor in rabbits and humans with pityrosporum orbiculare. | the purpose of this investigation was to produce experimental tinea versicolor in rabbits and humans with pityrosporum orbiculare. inoculation with p. orbiculare under plastic occlusion on the glabrous follicle-rich inside of the rabbit ear resulted in a tinea versicolor-like lesion after 1 week in 3 of 4 animals. one week after inoculation with p. orbiculare under plastic occlusion, experimental infections similar to those found clinically in tinea versicolor were seen in 10 of 12 patients with ... | 1979 | 448167 |
| taxonomy of exophiala jeanselmei (langeron) mcginnis and padhye. | the black yeast-like fungus exophiala jeanselmei (langeron) mcginnis et padhye was originally described as torula jeanselmei by langeron. since its original description in 1928, this dematiaceous hyphomycete has been placed in the genera phialophora, pullularia and rhinocladiella by various authors. study of the type culture of e. jeanselmei has confirmed that the principle conidiogenous cells of this fungus are annellides, thus supporting its current generic disposition. after reviewing the neo ... | 1978 | 570642 |
| taxonomy of exophiala werneckii and its relationship to microsporum mansonii. | study of the neotype culture of exophiala werneckii (cladosporium werneckii), as well as additional isolates, has shown that the yeast-like and hyphal conidiogenous cells are annellides. e. werneckii cannot be accommodated in cladosporium, a genus characterized by catenulate holoblastic coanidia. e. werneckii and the dematiaceous hyphomycete that castellani misidentified as microsporum mansonii (cladosporium mansonii) are two entirely different fungi. m. mansonii is considered to be a synonym of ... | 1979 | 575579 |
| pityrosporum species associated with dacryoliths in obstructive dacryocystitis. | two dacryoliths removed from the obstructed and enlarged lacrimal sac of a 54-year-old woman during dacryocystorhinostomy were found to contain filamentous forms consistent with pityrosporum orbiculare. to my knowledge, this fungus has not been observed before in a dacryolith or in dacryocystitis. | 1977 | 596394 |
| the occurrence of simple and mixed fungal infections in patients at the department of andrology/hamburg (1972--1976). | skin scales from 228 patients, referred to the department of andrology at the university of hamburg during 1972--76, were examined mycologically, because of being suspect of mycotic infections. in 54 cases dermatophytes were isolated, and yeasts were found in 13 cases. nocardia minutissima and malassezia furfur were present in 138 and 25 cases, respectively. in 12 patients, mixed infections were diagnosed; the infective organisms were yeasts in 46.2% of the cases, dermatophytes in 11.1%, and mal ... | 1978 | 717818 |
| a reappraisal of the role of pityrosporum orbiculare in pityriasis versicolor and the significance of extracellular lipase. | pityrosporum orbiculare is an obligate lipophilic yeast in vitro, which suggests it possesses an extracellular lipase crucial for nutrition. if present in vivo, the enzyme would enable the yeast to utilize skin surface lipids, which may therfore play an important role in the pathogenesis of pityriasis versicolor. cultured p. orbiculare and biopsy material from patients with pityriasis versicolor were investigated for the presence of lipase by electron microscope histochemistry. at sites of lipas ... | 1978 | 722119 |
| clinical evaluation of clotrimazole. a broad-spectrum antifungal agent. | the efficacy and safety of the broad-spectrum, topically applied antifungal agent clotrimazole were evaluated in two double-blind, multicentric trials. ten investigators reported on a total of 1,361 cases in which a 1% solution or a 1% cream formulation was compared with its respective vehicle. clotrimazole was therapeutically effective, as confirmed by mycological cure (negative microscopy and culture) and clinical improvement, in tinea pedis, tinea cruris, tinea corporis, pityriasis versicolor ... | 1976 | 769697 |
| ciclopirox: a new topical pyrodonium antimycotic agent. a double-blind study in superficial dermatomycoses. | one percent ciclopirox solution, a new topical antimycotic agent, was used in a double-blind controlled trial in 105 dermatomycosis patients. twelve of the patients were lost to follow-up. of the remaining ninety-three patients, forty-four were treated with the active drug, forty-nine with a placebo. the cure rate amongst those using ciclopirox was significantly superior to that of the placebo. the drug was effective against trichophyton rubrum, t. violaceum, t. mentagrophytes and malassezia fur ... | 1976 | 782504 |
| polymorphism of malassezia furfur. | alterations in the morphologic and physiologic characters of 11 isolates of pityrosporum orbiculare were noted upon prolonged maintenance in pure culture. successive subculturing of each isolate resulted in its progressive conversion from globose (p. orbiculare) through ovoid to cylindrical (p. ovale) form. globose forms utilized neither olive oil nor tween 20 as a sole carbon source, nor kno3 as a sole source of nitrogen, while ovoid and cylindrical forms utilized both of these carbon sources, ... | 1977 | 861851 |
| dimorphism of pityrosporum orbiculare in a defined culture medium. | dimorphism of pityrosporum orbiculare was induced in an artificial culture medium which consisted of 0.05 m glycine in 0.03-0.06 m ammonium phosphate buffer (ph 5.6), salts, glucose, and tween-80. of the strains tested, 78 to 85% produced hyphal elements from up to 8.5% of yeast cells. morphologic features of p. orbiculare in culture were examined by scanning electron microscopy and compared with the appearance of fungus from clinical lesions of tinea versicolor. morphologically, the fungi obtai ... | 1977 | 881572 |
| the effect of topical retinoic acid (airol) in the treatment of tinea versicolor. | a clinical trial with retinoic acid (airol) cream 0.05% applied topically was carried out on 50 patients suffering from tinea versicolor allocated to a random procedure. the results, judged in terms of cure rate, incidence of relapse and tolerance were very satisfactory. as regards the above mentioned criteria for a successful treatment, there was no significant difference between the lotion and cream groups. repigmentation of the affected skin after retinoic acid occurred in a relatively shorte ... | 1977 | 888002 |
| induction of hyphae in cultures of pityrosporum by cholesterol and cholesterol esters. | the effect of cholesterol and cholesterol esters on pityrosporum cultures has been studied. a mixture of 0.25% to 2.0% of cholesterol:cholesteryl stearate:glyceryl monostearate (2.0:1.5:2.0) added to bacto yeast morphology agar plus oleic acid was able to induce hyphae in cultures of both pityrosporum orbiculare and p. ovale. this result is discussed with respect to the cholesterol effect on cell membranes and to the occurrence of cholesterol and cholesterol esters in the scaling patches of pity ... | 1977 | 925376 |
| miconazole: a review of its antifungal activity and therapeutic efficacy. | miconazole2, a synthetic imidazole derivative, is a new topical antifungal agent for use in the local treatment of vaginal, and skin and nail infections due to yeasts and dermatophytes. it is particularly active against candida spp., trichophyton spp., epidermophyton spp., microsporum spp. and pityrosporon orbiculare (malassezia furfur), but also possesses some activity against gram-positive bacteria. in vaginal candidiasis, miconazole vaginal cream has produced higher cure rates than convention ... | 1975 | 1149649 |
| [occurrence of pityrosporum ovale in the human ear (author's transl)]. | | 1975 | 1213229 |
| growth requirements and lipid metabolism of pityrosporum orbiculare. | the yeast, pityrosporum orbiculare, isolated from lesions from lesions of tinea versicolor, grows in vitro only if fatty acids from the c12 to c24 series are added to the culture medium. except for elaidinic and nervonic acids, all saturated and unsaturated fatty acids tested support growth. p. orbiculare can synthesize various lipid fractions containing both saturated and unsaturated fatty acids from a single fatty acid. glucose and asparagine stimulate growth but exogenous vitamins do not. | 1976 | 1249447 |
| freeze-fracture replication of cultured pityrosporum orbiculare. | skin scrapings from a patient with pityriasis versicolor were plated on a bile salt medium containing 10% glycerol (for cryoprotection) and pityrosporum orbiculare was harvested for freeze-fracture replication. resting and budding cells were senn. the overall pattern of indentation of the plasma membrane towards the cytoplasm was well revealed as a spiral arrangement of major indentations with minor ones disposed more or less at right angles. hexagonally-arranged particles were not observed. mit ... | 1976 | 1265568 |
| dermatomycoses among industrial workers in cross river state, nigeria. | a survey of dermatomycoses was carried out amongst industrial workers in three different factories during the period 1987-1988. a total of 194 workers were screened, out of which 54 proved to be mycologically positive by microscopy and/or culture. incidence was apparently highest amongst workers in a cement factory (calcemco, 33.3%) followed by those in a wood factory (seromwood, 30.8%) and a rubber factory (crel, 26.2%). pityriasis versicolor was the predominant clinical type of dermatomycosis, ... | 1992 | 1302813 |
| interaction of azoles with rifampin, phenytoin, and carbamazepine: in vitro and clinical observations. | twelve patients receiving therapy with an azole agent (ketoconazole, itraconazole, and/or fluconazole) for systemic mycoses experienced drug interactions with rifampin, phenytoin, and/or carbamazepine resulting in substantial decreases in azole concentrations in serum. all four patients receiving azoles and concurrent phenytoin and/or carbamazepine failed to respond to treatment or suffered a relapse of their fungal infection. four of five patients with cryptococcosis who received itraconazole a ... | 1992 | 1315160 |
| anthralin is a potent inhibitor of pityrosporum orbiculare/ovale in vitro. | two strains of pityrosporum orbiculare/ovale were grown in a liquid medium and exposed to different concentrations of the imidazoles ketoconazole and clotrimazole as well as anthralin, liquor carbonis detergens and salicylic acid. with regard to growth inhibition of yeast cells, the efficacies of anthralin and the imidazoles were similar, a half-maximal inhibition being achieved with an anthralin concentration of 7 mg/l. liquor carbonis detergens and salicylic acid also inhibited growth of pityr ... | 1992 | 1350155 |
| pityrosporum ovale and atopic dermatitis in children and young adults. | children aged 0-21 years, 60 children with atopic dermatitis (ad), 40 children with rhinoconjunctivitis and or asthma (ra) and 40 children with no atopic history (hc) were studied to evaluate the relationship between skin colonisation with pityrosporum ovale and the occurrence of specific ige antibodies to p. ovale. the following studies were done: culture for p. ovale, measurement of ige antibodies to p. ovale (skin prick test, rast), candida albicans, and cladosporium herbarum (rast) and igg a ... | 1992 | 1357856 |
| crossreacting ige antibodies to pityrosporum ovale and candida albicans in atopic children. | sera from 13 patients with positive pityrosporum ovale skin prick test were analysed with ige immunoblotting. both p. ovale and candida albicans antigens were used to reveal possible crossreactivity of these yeasts. of the 13 sera, eight sera showed ige binding to p. ovale and six sera to c. albicans. simultaneous ige-binding to both c. albicans and p. ovale was observed in five of these sera. the most common ige-binding band pairs were, a 23 kd band of p. ovale and a 27 kd band of c. albicans, ... | 1992 | 1377092 |
| superficial fungal infections of the skin. diagnosis and current treatment recommendations. | superficial fungal infections are common. most diagnoses of fungal infections of the skin can be made by physical examination, assisted by the use of a wood's lamp, skin scrapings for microscopic examination, and fungal cultures. dermatophyte infections are common at all ages, in both sexes, and they have a worldwide distribution. these infections include tinea capitis, tinea cruris, tinea pedis, tinea corporis, tinea manuum and tinea barbae. tinea versicolor, caused by malassezia furfur, and ca ... | 1992 | 1379146 |
| [skin tests with pityrosporum ovale extract in atopic dermatitis]. | the etiology of atopic dermatitis is multifactorial. immediate-type sensitivity to the lipophilic yeast, pityrosporum ovale, may be important, especially in a subgroup of patients with dermatitis predominantly in the head and neck region. 100 patients with atopic dermatitis were investigated by means of skin prick tests, including pityrosporum ovale extract. positive tests were found more often in atopic patients with "head and neck"-dermatitis, but the correlation between a positive prick test ... | 1992 | 1412345 |
| [pustular dermatoses in the neonatal period]. | the diagnosis of pustular dermatosis occurring during the first months of life is usually based on clinical findings. however, some cases may require a few simple investigations including cytological studies, cultures, and skin biopsies. the most common causes of infectious pustular skin lesions include bacterial infections, which may be septicemic (with listeria as the leading causative agent) or initially localized (staphylococcus); viral infections (varicella, herpes); fungal infections, i.e. ... | 1992 | 1416661 |
| superficial mycoses in saudi arabia. | between june 1988 and december 1990, 1018 cases of superficial mycoses were investigated. diagnosis was confirmed by microscopic examination in 503 cases and the causal agent was isolated in 490 cases. tinea capitis accounted for 47.7% (92.5% in children below 10 years of age). the frequency of other clinical types in descending order was pityriasis versicolor 25.8%, tinea corporis 9%, onychomycosis 5.8%, tinea pedis 4%, intertrigo 3.9% and tinea cruris 2.8%. erythrasma was encountered three tim ... | 1992 | 1445094 |
| humoral responses to malassezia furfur serovars a, b and c in normal individuals of various ages. | a transferable solid-phase (tsp) elisa was developed for the determination of antibody titres specific to malassezia furfur serovars a, b and c in human sera. a survey of levels of class-specific antibodies (igm, igg and iga) to m. furfur serovars a, b and c in relation to age (2-64 years; 60 individuals) demonstrated that individuals had immunity to m. furfur by the age of 2-3 years. there was no difference in either igm or igg levels into adulthood. the only age-related differences were lower ... | 1992 | 1467286 |
| potentiation of antifungal activity of sesquiterpene dialdehydes against candida albicans and two other fungi. | the antifungal activity of two drimane sesquiterpene dialdehydes, polygodial (1) and warburganal (2), alone and in combination with several other substances, was examined against three fungi, candida albicans, saccharomyces cerevisiae and pityrosporum ovale employing a broth dilution method. anethole significantly synergized the activity of the two sesquiterpenoids against c. albicans and s. cerevisiae; however, it had only an additive effect against p. ovale. by contrast, two antioxidants, asco ... | 1992 | 1473583 |
| an improved method for quantitative culture of malassezia furfur. | quantitative culture of malassezia furfur from clinically healthy skin in 25 individuals was performed with two different methods using contact plates. the best results were obtained when a glucose peptone yeast extract medium, with the addition of milk, tween-60, glycerol and glycerol monostearate was used. different techniques for incubation and the reproducibility of this method were evaluated. incubation can be done in a plastic bag at 32 or 37 degrees c. this new method is simple, the colon ... | 1992 | 1488557 |
| [chronic otitis externa from the dermatologic viewpoint]. | chronic external otitis may be divided into several diagnostic categories. disposition for psoriasis, seborrhoeic and atopic eczema are main endogenous reasons. exogenous pathogens for external otitis are microbes and allergens. there are numerous interrelations by coincidence of dispositional diseases, e.g. psoriasis and atopic eczema and by combination of exogenous and endogenous pathogens. this holds good for the yeast pityrosporum ovale vs. orbiculare in seborrhoeic eczema and for the suscep ... | 1992 | 1492891 |
| ige antibodies to pityrosporum orbiculare and staphylococcus aureus in patients with very high serum total ige. | serum ige antibodies were detected with the radioallergosorbent test (rast) to a panel of allergens which included pityrosporum orbiculare, candida albicans, trichophyton rubrum, cladosporium herbarum, staphylococcus aureus, animal dander, deciduous tree pollens, grass pollens and foods in 81 consecutive patients with total ige greater than or equal to 3000 ku/l. data on atopic and infectious disease characteristics were collected by a questionnaire. ige antibody concentrations to p. orbiculare ... | 1992 | 1525694 |
| immunodiffusion test for diagnosing basidiobolomycosis. | an immunodiffusion test was developed for the diagnosis of basidiobolomycosis. when culture filtrate antigen (cfa) from basidiobolus ranarum was reacted against two human patient and two rabbit antisera, 2 precipitin bands, inner (n) and outer (y), were revealed for both patient and rabbit antisera. a line of identity was also observed between precipitin bands obtained with patient and rabbit sera. when cfa from b. ranarum (b cfa) was reacted against rabbit sera which contained antibody to conid ... | 1992 | 1528227 |
| a double-blind, placebo-controlled, multicenter trial of lithium succinate ointment in the treatment of seborrheic dermatitis. efalith multicenter trial group. | seborrheic dermatitis, an inflammatory dermatosis that principally affects sebaceous areas, may be related to the presence of the yeast pityrosporum ovale. topical therapy with corticosteroids, although in general effective, may be associated with several unwanted effects. the development of alternative non-steroid-based therapies may enable patients to avoid the use of topical steroids and help elucidate the pathogenesis of the disease. | 1992 | 1532964 |
| approaches to management of fungal infections in cancer patients. | the patient most susceptible to invasive aspergillosis has had prolonged granulocytopenia resulting from intensive chemotherapy and/or radiation therapy, aplastic anemia, or acute leukemia. the sinuses and lungs are usually involved, but the infection may disseminate to the endocardium, skin, cns, and eye. efficacy of antifungal treatment with amphotericin b depends on early recognition and aggressive intervention. in severe or refractory cases, addition of flucytosine, rifampin, or fluconazole ... | 1992 | 1534671 |
| fungemia due to malassezia furfur in patients without the usual risk factors. | | 1992 | 1554857 |
| human infections due to malassezia spp. | the genus malassezia contains three member species: malassezia furfur and malassezia sympodialis, both obligatory lipophilic, skin flora yeasts of humans, and malassezia pachydermatis, a nonobligatory lipophilic, skin flora yeast of other warm-blooded animals. several characteristics suggest the basidiomycetous nature of these yeasts, although a perfect stage has not been identified. classically, these organisms are associated with superficial infections of the skin and associated structures, in ... | 1992 | 1576583 |
| [in vitro antifungal activity of itraconazole, a new triazole antifungal agent, against clinical isolates from patients with dermatomycoses]. | in vitro antifungal activities of itraconazole (itz), a triazole antifungal agent, against clinical isolates obtained from patients with superficial and subcutaneous mycoses were examined using the agar dilution method on casitone agar. the clinical isolates tested were 7 species and 263 isolates including trichophyton mentagrophytes (104 isolates), trichophyton rubrum (103 isolates), microsporum canis (3 isolates), epidermophyton floccosum (2 isolates), candida albicans (32 isolates), malassezi ... | 1991 | 1652655 |
| ige-binding components in pityrosporum orbiculare identified by an immunoblotting technique. | ige-binding components in crude extracts of pityrosporum orbiculare were separated by sodium dodecylsulphate polyacrylamide gel electrophoresis and transferred to immobilon membrane. the components were detected by p. orbiculare radioallergosorbent (rast) positive sera (class 2-4) from 37 patients with atopic dermatitis and visualized by enzyme-labelled anti-human ige antibodies in chromogenic substrate. numerous ige-binding compounds were demonstrated in the molecular weight (mw) range of 14-94 ... | 1991 | 1676206 |
| immune reactions to pityrosporum ovale in adult patients with atopic and seborrheic dermatitis. | pityrosporum ovale is a lipophilic yeast commonly present in the seborrheic areas of the skin of adults. fifty-five young adult patients with atopic dermatitis, 19 patients with seborrheic dermatitis, and 19 healthy control subjects were examined for immune reactions to p. ovale, including tests for specific ige antibodies (prick test, histamine release), igg antibodies and epicutaneous testing. ige antibodies against p. ovale were found in two thirds of the patients with atopic dermatitis and w ... | 1990 | 1693386 |
| atopic dermatitis of the face, scalp, and neck: type i reaction to the yeast pityrosporum ovale? | we have previously reported that a lipophilic yeast, pityrosporum ovale (p. ovale) produced a high frequency of positive skin prick tests and in vitro histamine-release (hr) tests in patients suffering from atopic dermatitis (ad) of the face, scalp, and neck. in the present study, our aim was to confirm the involvement of p. ovale-specific ige and to produce a standardized extract for diagnostic tests; 7/20 sera from patients with a positive hr test were positive in rast. several ige-binding pro ... | 1992 | 1730839 |
| malassezia furfur infections. | | 1991 | 1753084 |
| malassezia furfur septicaemia in a child with leukaemia. | | 1991 | 1753146 |
| is pityrosporum ovale a pathogen of the external auditory meatus? | fifteen dry wax samples, 15 wet wax samples and 7 dandruffy skin samples obtained from the external auditory meatus (eam) of 26 individuals (age range from 1 to 76 years) were examined for the identification of pityrosporum ovale. after staining the samples with gram's stain, cultures were made on sabouraud's medium with olive oil added. thirteen of the dry wax samples, 1 of the wet wax samples and 6 of the dandruffy skin samples harboured p. ovale. lipophilic yeast is frequently present in dry ... | 1991 | 1759582 |
| [neonatal pustulosis induced by malassezia furfur]. | | 1991 | 1789660 |
| the detergent scrub method for quantitative determination of malassezia furfur on chest and back skin: comparative evaluation of three different media. | the quantitative determination of malassezia furfur on normal human skin has been considered as difficult until recently. during the last years, however, several different media have been described which facilitate the quantification of m. furfur. as the efficacy of these media is still controversial, three different media were compared analyzing the chest and back of 20 healthy young adult volunteers. the highest counts of colony-forming units (cfu) per cm2 were found using a medium containing ... | 1991 | 1795726 |
| ultrastructure of budding process of malassezia pachydermatis. | the ultrastructure of malassezia pachydermatis and its budding process was investigated by scanning and transmission electron microscopy. the innermost layer of the cell wall showed the serrated structure characteristic of the genus malassezia. in the daughter cell, this structure became more defined as the cell grew. the mode of conidium ontogeny was monopolar blastic development with a collarette. the appearance was similar to that reported previously for malassezia furfur, with the following ... | 1991 | 1815031 |
| pityrosporum folliculitis in the philippines: diagnosis, prevalence, and management. | sixty-eight typical cases were studied to define the course of pityrosporum folliculitis in a tropical setting. contrary to reports in the literature, we found pityrosporum folliculitis to be polymorphic. the "molluscoid" comedopapule was the most characteristic and common lesion, and it yielded consistently high spore counts. the face was commonly involved. to establish the diagnosis, we used direct microscopy of potassium hydroxide/parker blue-black ink mounts of the lower poles of comedonal p ... | 1991 | 1831207 |
| enhanced phagocytosis and intracellular killing of pityrosporum ovale by human neutrophils after exposure to ketoconazole is correlated to changes of the yeast cell surface. | in seborrhoeic dermatitis an inflammatory response occurs secondary to large numbers of pityrosporum yeasts appearing within and beneath the epidermis. to study the interaction between human neutrophils and p. ovale and any immunomodulating effect of antifungal agents, the yeast was exposed to ketoconazole and then incorporated into neutrophil monolayer assays. phagocytosis was complement dependent and reached a maximum after 40 min. ketoconazole at 25, 50 and 100 mg l-1 had no significant effec ... | 1991 | 1833641 |
| pityrosporum ovale/orbiculare in papillomatous nevus cell nevi. | 62% of 200 papillomatous nevus cell nevi compared to 45% of 40 seborrheic keratoses showed the presence of pityrosporum ovale/orbiculare (malassezia furfur) on their surface, supposedly representing a saprophytic state of the microorganisms in vivo. the papillomatous nevus cell nevi were of the compound or dermal type. significant inflammation, dysplasia or major changes in color were absent. electron microscopy revealed the characteristic, sometimes budding fungal cells. a relationship between ... | 1991 | 1835942 |
| an immunological study in patients with seborrhoeic dermatitis. | the humoral and cellular immune-status was studied in 30 patients with seborrhoeic dermatitis. increased frequencies of natural killer cells were found in 46% of patients. furthermore, subnormal mitogen stimulation responses were demonstrated in 13 patients, whereas two individuals were found to have very high numbers of activated t lymphocytes in peripheral blood. higher-than-normal total serum igg and iga was observed in 14 and 11 patients, respectively. for nine of 12 patients with skin lesio ... | 1991 | 1838969 |
| seborrhoeic dermatitis and pityrosporum ovale: cultural, immunological and clinical studies. | seborrhoeic dermatitis is a common skin disease mainly affecting the scalp and face. the etiology of seborrhoeic dermatitis is unknown but a connection with the lipophilic yeast pityrosporum ovale has been found in a number of treatment studies. p. ovale belongs to the normal cutaneous flora but is also an opportunistic pathogen. the purpose of these studies was to examine how the density of p. ovale changes with age, to determine the number of p. ovale in seborrhoeic dermatitis compared to cont ... | 1991 | 1839943 |
| prevalence of dermatophytes and yeasts (candida spp., malassezia furfur) in hiv patients. a study of former drug addicts. | the prevalence of dermatophytes and yeasts (candida spp. and pityrosporum spp.) was studied in 40 former drug-addicts, all of whom were hiv seropositive but otherwise had no other symptoms (2nd stage cdc atlanta, 1987). we considered 7 skin areas for dermatophytes and pityrosporum spp. (scalp, forehead, nose, back, chest, groin, toe webs) and the mouth for yeasts. dermatophytes were found in 8 (20%) and tinea pedis was the most common dermatophytosis: tricophyton rubrum was the fungus most frequ ... | 1991 | 1875983 |
| ige antibodies to pityrosporum ovale in atopic dermatitis. | an enzyme-linked immunosorbent assay (elisa) was developed to assess serum ige antibodies directed against pityrosporum ovale in patients with atopic dermatitis (ad), atopic patients with allergic respiratory disease (ard: rhinitis or asthma) but without eczema, and in healthy controls. ige binding to p. ovale extract was demonstrated in 49% (35/72) of ad patients. in contrast, anti-p. ovale ige was found in only one of 27 atopic controls without eczema; all healthy control sera (n = 17) were ne ... | 1991 | 1911314 |
| complications associated with central venous catheters inserted in critically ill neonates. | to assess the incidence and spectrum of complications associated with central venous catheter (cvc) placement in the critically ill infant. | 1991 | 1940277 |
| the effects of saperconazole on the morphology of candida albicans, pityrosporum ovale and trichophyton rubrum in vitro. | fungal cultures were incubated for various periods of time with saperconazole at concentrations ranging from 10(-10) to 10(-5) m: candida albicans (4 and 24 h), pityrosporum ovale (2 and 7 days), and trichophyton rubrum (1, 2, 3, 7 and 14 days). at the end of the incubation period, fungal morphology was compared with that of control cultures by transmission and scanning electron microscopy. in all three species, major ultrastructural changes were seen from concentrations of 10(-8) to 10(-7) m sa ... | 1991 | 1955949 |
| [in vitro antifungal activity of amorolfine against malassezia species]. | in vitro antifungal activities of a new morpholine agent, amorolfine (mt-861) were investigated, against 39 strains of malassezia furfur (11 stock cultures and 28 clinical isolates) and 8 strains (stock cultures) of malassezia pachydermatis, in comparison with those of 2 reference drugs, clotrimazole (ctz) and bifonazole (bfz). of the 3 antifungal agents, mt-861 exhibited strongest antifungal activities against the stock cultures of m. furfur and m. pachydermatis with average mic values of 0.428 ... | 1991 | 1960851 |
| [in vitro antifungal activity of amorolfine, a new morpholine antimycotic agent]. | in vitro antifungal activities of amorolfine (mt-861), a newly developed morpholine antimycotic agent, against a wide range of pathogenic fungal strains were investigated using an agar-dilution method with an imidazole antifungal agent, clotrimazole (ctz), as the reference drug. the results showed that mt-861 had a broad antifungal spectrum, and was active against all of the pathogenic fungi tested except nonpigmented filamentous fungi such as aspergilli and penicillia. dermatophytes and malasse ... | 1991 | 1960861 |
| the effect of ketoconazole and itraconazole on the filamentous form of pityrosporum ovale. | the effect of ketoconazole and itraconazole on the filamentous form of pityrosporum ovale in vitro was studied. in a recently developed model, using human stratum corneum in vitro, p. ovale transformed into the filamentous form in 25-30% of the cells. ketoconazole and itraconazole in concentrations of 0.01, 0.1 and 1 microgram/ml were incubated together with p. ovale cells on human stratum corneum pieces placed on a lipid-enriched culture medium. both agents effectively blocked the production of ... | 1990 | 1969209 |
| malassezia furfur catheter infection cured with antibiotic lock therapy. | | 1991 | 1986581 |
| malassezia furfur fungemia associated with central venous catheter lipid emulsion infusion. | malassezia furfur has been associated with fungemias in infants after prolonged intravenous lipid emulsion alimentation. most cases of m. furfur fungemia reported in the literature involved neonates and required catheter removal for cure. m. furfur is probably an underreported problem in neonates as well as adults with central venous catheters, receiving lipid emulsions, because the organism requires selective enrichment media for growth, for example, sabouraud's dextrose agar with sterile olive ... | 1991 | 1988397 |
| malassezia furfur infection in the nicu. | | 1991 | 2038277 |
| malassezia furfur colonization of neonates in an intensive care unit. | we studied malassezia furfur colonization of neonates in the neonatal intensive care unit (nicu) and found that the rate was astonishingly high as compared to the previous studies. in very low birth weight (less than 1,000 g) infants we recorded a colonization rate of 80%, and 4% infants with a birth weight greater than 2,000 g. under 10 day's hospitalization the rate was 11%, and it was 70% after 20 days spent in the unit. among the infants with the birth weight less than 1,700 g, antibiotic th ... | 1990 | 2103591 |
| the permissive effect of sebum in seborrhoeic dermatitis: an explanation of the rash in neurological disorders. | the hypothesis that sebum permits the growth of pityrosporum ovale, and hence the development of seborrhoeic dermatitis, was tested by observing whether a reduction of sebum production by isotretinoin would improve the disorder. in 10 male patients with seborrhoeic dermatitis, treatment with isotretinoin for 6 weeks reduced the mean sebum excretion rate by 70% and improved the severity of the rash, but with a site difference in magnitude of response. it is concluded that the residual pool of seb ... | 1990 | 2137011 |
| skin surface electron microscopy in pityrosporum folliculitis. the role of follicular occlusion in disease and the response to oral ketoconazole. | the yeast pityrosporum orbiculare is thought to cause the folliculitis associated with seborrheic eczema. however, a combination of mechanical and microbiological factors may be involved, with follicular occlusion leading to yeast overgrowth and folliculitis. scanning electron microscopy was used to investigate this hypothesis. skin biopsy specimens obtained from patients with pityrosporum folliculitis were examined by scanning electron microscopy before and after oral ketoconazole therapy. pati ... | 1990 | 2137322 |
| onychomycosis and aids. clinical and laboratory findings in 62 patients. | the results of a study on onychomycosis in aids related complex and aids patients presenting for dermatology consultation at an infectious diseases department are reported. the clinical results showed that most patients presented a proximal white superficial onychomycosis. the association with a clinical interdigital involvement was rare, but the association with a mycotic plantar keratoderma was more frequent. the laboratory results showed that dermatophytes were the most frequent etiologic age ... | 1990 | 2141830 |
| the in vitro antifungal activity of ketoconazole, zinc pyrithione, and selenium sulfide against pityrosporum and their efficacy as a shampoo in the treatment of experimental pityrosporosis in guinea pigs. | the fungistatic and fungicidal activity of ketoconazole, zinc pyrithione, and selenium sulfide against pityrosporum, a yeast thought to play a pathogenic role in seborrheic dermatitis and dandruff, was assessed in dixon broth for pityrosporum ovale and sabouraud broth for pityrosporum pachydermatis. ketoconazole inhibited growth at concentrations ranging from 0.001 to 1 micrograms/ml. for zinc pyrithione and selenium sulfide higher concentrations were needed. in a guinea pig model the efficacy o ... | 1990 | 2142498 |
| skin surface electron microscopy in pityrosporum folliculitis. the role of follicular occlusion in disease and the response to oral ketoconazole. | the yeast pityrosporum orbiculare is thought to cause the folliculitis associated with seborrheic eczema. however, a combination of mechanical and microbiological factors may be involved, with follicular occlusion leading to yeast overgrowth and folliculitis. scanning electron microscopy was used to investigate this hypothesis. skin biopsy specimens obtained from patients with pityrosporum folliculitis were examined by scanning electron microscopy before and after oral ketoconazole therapy. pati ... | 1990 | 2143368 |
| the role of pityrosporum ovale in seborrheic dermatitis. | this paper discusses the relation between the lipophilic dimorphic yeast pityrosporum ovale and seborrheic dermatitis. a review of studies concerning the microbiology in seborrheic dermatitis and immune reactions to p ovale are given. in our own studies with quantitative cultures, no significant difference was found in the number of p ovale in patients compared with controls, or between healthy and lesional skin in the patient group. igg serum antibodies against p ovale cells estimated with indi ... | 1990 | 2149500 |
| common cutaneous disorders in athletes. | athletic activity may cause or aggravate skin disorders, which in turn may diminish athletic performance. since many sporting activities necessitate prolonged exposure to the sun, athletes must avoid painful sunburn which will adversely affect their performance. drugs and chemicals also may cause photoallergic and/or phototoxic reactions, including polymorphous light eruption and athletes should thus avoid photosensitising drugs and chemicals. the effects of chronic ultraviolet exposure include ... | 1990 | 2180022 |
| [the history of dandruff and dandruff in history. a homage to raymond sabouraud]. | in one of his books, written at the beginning of this century, raymond sabouraud devotes some 280 pages to the history of dandruff. their reading illustrates how, from the greeks to sabouraud's era, this desquamative disease has been subjected to endless doctrinal and scientific conflicts, long before the so-called "present" controversies. one of the early conflicts, between celsus and galen, lies in the nature of the squames, i. e. dry or exudating, leading to the inclusion (or non inclusion) o ... | 1990 | 2181905 |
| differentiation of three serovars of malassezia furfur. | malassezia furfur strains were isolated from the clinically normal skin of 10 volunteers by swabbing four different sites (forehead, ear, back and chest). the strains could be divided into three basic groups on the basis of cultural characteristics. both unabsorbed and absorbed specific rabbit antisera were prepared against nine of the strains, and both species and group specific antigens could be demonstrated. serologically, three group specific surface antigens could be identified which corres ... | 1990 | 2196254 |
| enzyme-linked immunosorbent assay (elisa) for detection of antibodies against pityrosporum orbiculare. | igg antibodies to pityrosporum orbiculare were detected by an enzyme-linked immunosorbent assay (elisa) in sera from 10 healthy adults and five healthy 6-month-old children. the elisa showed 17-80 times higher antibody levels in adults than were found by an indirect immunofluorescence technique (iif) used in earlier studies. low titres of antibody were detected in the children. | 1990 | 2213440 |
| the normal microbial flora of the outer ear canal in healthy norwegian individuals. | the microbial flora of the outer ear canal was determined for 77 healthy individuals (m = 44, f = 33). no growth of any microbe was found in 5% of males and 15% of females. coagulase-negative staphylococci, dominated by staphylococcus epidermidis, were the commonest microbe group found (83% of persons sampled). staphylococcus aureus was found in 7% males and no females. diptheroids were cultured from 32% of the samples. the only gram-negative rod found was hafnia alvei in 4% of individuals. no v ... | 1990 | 2216049 |
| the role of microorganisms in atopic dermatitis. | the course of atopic dermatitis is widely determined by environmental factors such as physical or psychogenic stress and reactions to allergens or microorganisms. the latter include bacteria, viruses and fungi, especially staphylococcus auerus, herpes simplex virus (hsv), and pityrosporum orbiculare. in childhood, impetigo around the big joints is frequently seen, while the characteristic reaction to s. auerus in the young adults is pruritic pustules on the extremities or an exacerbation of the ... | 1990 | 2285570 |
| the influence of various factors on the human resident skin flora. | various factors, e.g. prolonged occlusion, skin disinfectants, systemic antimicrobials, can have an impact on the ecosystem of the normal human skin flora for a short time. these impacts are of clinical importance in the treatment of some skin diseases, where members of the normal human skin flora are involved in the pathogenesis of the disease, e.g. propionibacterium acnes in acne vulgaris, corynebacterium species in erythrasma, trichomycosis palmellina and pitted keratolysis, pityrosporum orbi ... | 1990 | 2285575 |
| ige antibodies to pityrosporum orbiculare in children with atopic diseases. | ige antibodies to pityrosporum orbiculare and 16 other species of fungi were measured with the radioallergosorbent test (rast) in sera of 131 children. the children were 7-18 years old, suffered from atopic diseases and showed a varied allergic profile on a skin prick test (spt). ige antibodies to p. orbiculare were found in the sera of 26 of the 131 children. a higher proportion of the p. orbiculare rast positive children than of the negative ones had current eczema (p less than 0.0001). in a s ... | 1990 | 2333749 |
| changes in fungal ultrastructure after short-course ciclopiroxolamine therapy in pityriasis versicolor. | the clinical outcome and the effects on morphogenesis and cell ultrastructure induced by a 1% ciclopiroxolamine solution in six patients with proven pityriasis versicolor were studied. treatment regimens consisting of a once-daily application for 1 day, 2 days (days 1 and 4) or 3 days (days 1, 4 and 8). clinical evaluation, scanning (sem) and transmission electron microscopy (tem) were performed on skin scrapings before treatment, and at 3, 7, 15 and 21 days after the start of therapy. sem techn ... | 1990 | 2347114 |
| the phototoxic inhibitory effect and phototoxic killing effect of micro-organisms. | the toxic and phototoxic growth inhibitory and killing effect of staphylococcus aureus, s. epidermidis, escherichia coli, pseudomonas aeruginosa, streptococcus pyogenus gr. a, st. viridans, pityrosporum ovale and candida albicans were studied. p. ovale and st. viridans were the only micro-organisms with any toxic effect against the other micro-organisms tested. p. ovale inhibited the growth of s. aureus, s. epidermidis, ps. aeruginosa and e. coli. st. viridans inhibited the growth of s. aureus, ... | 1990 | 2371170 |
| [electron microscopy study of amorolfin action against malassezia furfur (robin) baillon]. | during 48 hours, yeasts (malassezia furfur) are brought into contact with a new antifungal agent of broad antifungal spectrum, amorolfine, used with the following concentrations: 0.1, 0.5, 1, 2, 5, 10 micrograms/ml. after centrifugation, pellets are fixed, using the conventional technique of electron microscopy. although the cell wall seems intact, the changes observed at the level of the cytoplasm and of the cell organels can be compared to those observed in blastospores of c. albicans. this an ... | 1990 | 2385455 |
| semipermeable dressing and transepidermal water loss in premature infants. | within the first days of life, 10 infants, of 32 weeks' gestational age or less, began 2 weeks of treatment with a semipermeable wound dressing over a small area of skin. the effects of the dressing on transepidermal water loss and cutaneous microflora were evaluated. transepidermal water loss from the semipermeable dressing-treated skin was significantly less than that from the untreated skin immediately after placement of the dressing (8.1 +/- 1.8 g/m2.h-1 vs 17.7 +/- 3.5 g/m2.h-1, p less than ... | 1990 | 2388784 |
| the effect of uv-light on human skin microorganisms. | pityrosporum orbiculare, candida albicans, staphylococcus epidermidis and s. aureus were irradiated with uva and uvb light in vitro. uvb inhibited growth much more effectively than uva. p. orbiculare was the most sensitive and s. aureus the least sensitive organism. with a dose of 900 mj cm-2 of uvb a 50 times reduction in number of colony forming units was seen for s. aureus and for the other organisms a total inhibition of growth was seen. when p. orbiculare was irradiated with monochromatic l ... | 1987 | 2436418 |
| experimental folliculitis with pityrosporum orbiculare: the influence of host response. | the aetiology of the folliculitis associated with seborrhoeic eczema is unclear, though the yeast, pityrosporum orbiculare has been implicated. p. orbiculare was applied under occlusion to normal forearm skin of patients with seborrhoeic eczema (se), seborrhoeic eczema and folliculitis (sef), and normal controls. there were significant differences in response to occlusion between the three groups. those patients with previous clinical evidence of folliculitis (sef) developed folliculitis at the ... | 1987 | 2448999 |
| a case of confluent and reticulate papillomatosis (gougerot-carteaud) with an unusual location. | a 15-year-old female with a brown hyperkeratotic plaque in the pubic region confirming with the diagnosis of confluent and reticulate papillomatosis (crp) is presented. the lesion disappeared rapidly after 3 weeks of treatment with 50% propylene glycol in water. the etiological role of pityrosporum orbiculare in crp is discussed. | 1988 | 2453997 |
| studies on the lipophilic yeast pityrosporum ovale in hiv-seropositive and hiv-seronegative homosexual men. | pityrosporum ovale has been implicated in the pathogenesis of seborrheic dermatitis, a dermatosis occurring with high prevalence in symptomatic hiv-infected individuals. quantitative cultures for p. ovale were taken in 12 hiv-seropositive patients and in 12 hiv-seronegative controls. sera were analysed for antibodies to p. ovale. in hiv-seropositive patients, lymphocyte subsets were analysed. the mean number of p. ovale/cm2, the mean serum antibody titres against this yeast and the occurrence of ... | 1988 | 2461026 |
| variations of pityrosporum orbiculare in middle-aged and elderly individuals. | pityrosporum orbiculare was cultured from clinically normal skin in 60 adults, 30 to 80 years of age. antibody titers against p. orbiculare in serum and lipid measurements were also estimated. there was a parallel between a reduction in number of cultured organisms and an increase in age (p = 0.002, multiple linear regression analysis). the lipid content of the skin in older people was lower than that in young and middle aged (p = 0.0002). this may be an explanation for the decrease in number of ... | 1988 | 2467495 |
| malassezia furfur fungaemia in infants receiving intravenous lipid emulsions. a rarity or just underestimated? | malassezia furfur fungaemia is reported in six preterm infants receiving a parenteral fat emulsion through a deep central venous catheter. the fungus was detected in blood cultures drawn through the catheter. the features of these cases are compared to those reported since 1981, when m. furfur was described for the first time as a cause of deep tissue infection. clinical signs such as fever, in spite of broad-spectrum antibiotics, and the presence of pulmonary infiltrates, associated with leucoc ... | 1989 | 2493378 |
| malassezia furfur--disseminated infection in premature infants. | three infants, born prematurely, died after clinical illnesses of 67, 65, and 60 days from infection by malassezia furfur. each infant had been nourished with lipid emulsions delivered through deep-line catheters. the infections, all discovered at autopsy, were characterized by massive involvement of lungs. two of the three had endocardial vegetations containing m. furfur; all three had lesions in liver, kidney, and spleen, and two had lesions in adrenal, pancreas, and colon. in addition, one of ... | 1989 | 2510495 |