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screening of 34 indian medicinal plants for antibacterial properties.a total of 34 plant species belonging to 18 different families, selected on the basis of folklore medicinal reports practised by the tribal people of western ghats, india, were assayed for antibacterial activity against escherichia coli, klebsiella aerogenes, proteus vulgaris, and pseudomonas aerogenes (gram-negative bacteria) at 1000-5000 ppm using the disc diffusion method. of these 16 plants showed activity; among them cassia fistula, terminalia arjuna and vitex negundo showed significant ant ...19989741889
common environmental allergens causing respiratory allergy in india.respiratory allergy affects all age groups but the children are the worst affected by the respiratory allergy. bioparticles from different biological sources are the main cause of allergy. pollen grains, fungal spores, insect and other materials of biological origin form the most important allergen load in the air. for the efficient diagnosis of the allergy and its effective treatment it is very important to know about the prevalence, seasonal and annual variations of aeroallergens of the area. ...200212003301
evaluation of air pollution phytotoxicity downwind of a phosphate fertilizer factory in india.the effects of air pollution on plants downwind of a fertilizer factory at udaipur, india, were studied using three woody perennials. seedlings of these species including a shrub (carissa carandas l.), a leguminous avenue tree (cassia fistula l.) and a fruit tree (psidium guajava l.) were grown in earthen pots at different study sites receiving varying levels of air pollution input. changes in plant growth, morphological characteristics, photosynthetic pigment, ascorbic acid, n and s contents an ...200515727311
wound healing potential of cassia fistula on infected albino rat model.infection is the major problem to treat the wound. antibiotic resistance by the pathogenic microorganism renders drug ineffective and calls for improved designing and development of new drugs. new approach has been developed to isolate active components from botanicals. our aim was to investigate the potential of cassia fistula to treat the infected wound on albino rat model.200616242721
search for antibacterial and antifungal agents from selected indian medicinal plants.a series of 61 indian medicinal plants belonging to 33 different families used in various infectious disorders, were screened for their antimicrobial properties. screening was carried out at 1000 and 500 microg/ml concentrations by agar dilution method against bacillus cereus var mycoides, bacillus pumilus, bacillus subtilis, bordetella bronchiseptica, micrococcus luteus, staphylococcus aureus, staphylococcus epidermidis, escherichia coli, klebsiella pneumoniae, pseudomonas aeruginosa, streptoco ...200616678369
total phenol, antioxidant and free radical scavenging activities of some medicinal plants.phenols, a major group of antioxidant phytochemicals, have profound importance due to their biological and free radical scavenging activities. to identify their potential sources, extracts of some plants were studied for their total phenolic content (tpc), antioxidant (aoa) and free radical scavenging activities (frsa) by different methods at multiple concentrations followed by specific phenolic composition. the amount of tpc varied from 2.8 mg/g (withania somnifera, roots) to 107.8 mg/g (cassia ...200717415953
activity of synergistic combination amoxy-cassia against salmonella.the object of this study was to formulate new, cost effective anti-microbial combination for multi drug resistant (mdr) salmonella enterica serover typhi (sest) based on the synergistic activity of amoxicillin with the aqueous fruit solution of cassia fistula (cff), a medicinal plant found in pakistan which when tested alone have weak antimicrobial activity against blood isolates of mdr sest. mic of mdr sest for amoxicillin and cff alone was 750 microg/ml and 3750 microg/ml. the mic of amoxicill ...200717416570
antibacterial and antifungal activity of cassia fistula l.: an ethnomedicinal plant.hexane, chloroform, ethyl acetate, methanol and water extracts from the flower of cassia fistula (an ethnomedicinal plant) were tested against bacteria and fungi. all the extracts exhibited antibacterial activity against gram-positive organisms with minimum inhibitory concentrations (mic) between 0.078 and 2.5 mg/ml. among the gram-negative bacteria, only pseudomonas aeruginosa was susceptible to the extracts. ethyl acetate crude extract was fractionated using chromatographic techniques. a cryst ...200717532583
ecological niche of cryptococcus neoformans var. grubii and cryptococcus gattii in decaying wood of trunk hollows of living trees in jabalpur city of central india.cryptococcus neoformans var. grubii and c. gattii were repeatedly isolated from decaying wood of trunk hollows in living trees growing in jabalpur city in central india. the isolation of c. gattii has been reported from decayed wood inside trunk hollow of tamarindus indica (15.6%), mangifera indica (2.2%), pithecolobium dulce (12.5%), syzygium cumini (14%), and one from bark of s. cumini. c. n. var. grubii was isolated from decaying wood debris of t. indica (4.4%), m. indica (13.3%), terminalia ...200717661160
biochemical parameters of plants as indicators of air pollution.in the present study species like mangifera indica, linn., cassia fistula, linn., and eucalyptus hybrid were exposed to different air pollution load for short duration (active biomonitoring). variation in biochemical parameters like chlorophyll, protein, soluble sugar free amino acid, ascorbic acid, nitrate reductase, superoxide dismutase and peroxidase in the leaves were found to be pollution load dependent. these variations can be used as indicators of air pollution for early diagnosis of stre ...200717717999
antiparasitic activity of biochanin a, an isolated isoflavone from fruits of cassia fistula (leguminosae).the fractionation through bioguided antileishmanial activity of the dichloromethane extract of cassia fistula fruits (leguminosae) led to the isolation of the active isoflavone biochanin a, identified by spectroscopic methods. this compound showed 50% effective concentration (ec(50)) value of 18.96 microg/ml against promastigotes of leishmania (l.) chagasi. the cytotoxicity of this substance against peritoneal macrophages resulted in an ec(50) value of 42.58 microg/ml. additionally, biochanin a ...200918810492
bioefficacy of cassia fistula linn. (leguminosae) leaf extract against chikungunya vector, aedes aegypti (diptera: culicidae).the leaf extract of cassia fistula with different solvens viz, methanol, benzene and acetone were studied for the larvicidal, ovicidal and repellent activity against aedes aegypti. the extract exhibited dose dependent activity and produced significant mortality. the 24 h lc50 concentration of the extract against aedes aegypti were observed at 10.69, 18.27 and 23.95 mg/l respectively. mean percent hatchability of the ovicidal activity was observed 120.00 h after treatment. the percent hatchabilit ...200919499844
modulation of humoral immunity by cassia fistula and amoxy-cassia.immonomodulatory effect of fruit of c fistula, a traditional medicinal plant and its synergistic antimicrobial combination with amoxicillin named amoxy-cassia (patent # 1371240, government of pakistant) studied on humoral immune system of balb/c mice. animal immunized with sheep rbc and treated with c. fistula fruit, amoxycassia, amoxicillin and saline number of activated anti-srbc producing cell in spleen calculated by haemolytic plaque assay. antibody titer in blood was measured by haemaggluti ...200818166514
biochemical changes in plant leaves as a biomarker of pollution due to anthropogenic activity.the air pollution due to anthropogenic activities seriously affected human life, vegetation, and heritage as well. the vegetation cover in and around the city mitigates the air pollution by acting as a sink for pollution. an attempt was made to evaluate biochemical changes occurred in four selected plant species, namely azadirachta indica, mangifera indica, delonix regia, and cassia fistula of residential, commercial, and industrial areas of nagpur city in india. it was observed that the correla ...201120721619
genetic diversity in some perennial plant species with-in short distances.distinct morphophysiological variations observed for over 2 years with-in short distances among four perennial plants indicated genetic diversity among the lines growing at three places. the isozyme and sds polyacrylamide gel banding patterns as genetic markers were used to investigate four perennial species, namely dalbergia sissoo roxb., delonix regia (boj.) refin., cassia fistula l. and calotropis procera r. br. plant materials collected from three locations (agra, gwalior and lucknow) differ ...200717717991
protective effect of cassia fistula linn. on diethylnitrosamine induced hepatocellular damage and oxidative stress in ethanol pretreated rats.diethylnitrosamine (den), found in many commonly consumed foods, is widely reported to induce cancer in animals and humans. the aim of the present study was to investigate the hepatoprotective and antioxidant activities of the leaf extract of the medicinal plant cassia fistula linn. against diethylnitrosamine induced liver injury in ethanol pretreated rats. albino wistar rats, pretreated with ethanol for 15 days, were administered a single dose of den. thirty days after den administration, hepat ...201021157638
isolation of antileishmanial sterol from the fruits of cassia fistula using bioguided fractionation.natural products represent a rich source of new chemical entities for the development of drugs for neglected diseases. leishmaniasis still afflicts the poorest populations in the world, with 12 million cases worldwide. this work analysed crude extracts and fractions from the fruits of cassia fistula against the most dramatic and fatal disease form of leishmaniasis, the visceral form (vl). hexane extract from the fruits showed significant antileishmanial activity against the promastigote form of ...200717397117
effect of cassia fistula linn. leaf extract on diethylnitrosamine induced hepatic injury in rats.the hepatoprotective and antioxidant effect of cassia fistula linn. leaf extract on liver injury induced by diethylnitrosamine (den) was investigated. wistar rats weighing 200+/-10g were administered a single dose of den (200mg/kg b.w., i.p.) and left for 30 days. for hepatoprotective studies, ethanolic leaf extract (ele) of c. fistula linn. (500mg/kg b.w., p.o.) was administered daily for 30 days. ast, alt, alp, ldh, gamma-gt and bilirubin were estimated in serum and liver tissue. lipid peroxid ...200717289008
endophytic phomopsis species: host range and implications for diversity estimates.foliar endophyte assemblages of teak trees growing in dry deciduous and moist deciduous forests of nilgiri biosphere reserve were compared. a species of phomopsis dominated the endophyte assemblages of teak, irrespective of the location of the host trees. internal transcribed spacer sequence analysis of 11 different phomopsis isolates (ten from teak and one from cassia fistula) showed that they fall into two groups, which are separated by a relatively long branch that is strongly supported. the ...200616917524
preliminary phytochemical screening of four common plants of family caesalpiniaceae.preliminary phytochemical screening of bauhinia variegata, cassia fistula, cassia tora and tamarindus indica did not reveal alkaloids and unbound anthraquinones while glycosides as well as flavonoids were present in all the four species of the family caesalpiniaceae. cardiac glycosides were absent only in c. tora and saponins were present only in t. indica, b. variegata and t. indica were devoid of bound anthraquinones while bound anthraquinones were present in c. fistula and c. tora. paper chro ...198916414637
a new minor dimmeric ester from seeds of cassia fistula l. (leguminosae).bioactivity-guided fractionation of n-hexane phase from meoh extract of the seeds of cassia fistula l. (leguminosae) yielded two bioactive substances against cladosporium cladosporioides and c. sphaerospermum. after spectroscopic analysis, these compounds were characterised as the known benzyl 2-hydroxy-3,6-dimethoxybenzoate and its dimer dibenzyl 2,2'-dihydroxy-3,6,3?,6?-tetramethoxy-biphenyl-1,1'-dicarboxylate, which showed a new structural arrangement.201121756186
effect of pretreatment of cassia fistula linn. leaf extract against subacute ccl4 induced hepatotoxicity in rats.ccl4 alone treatment (0.lml of liquid paraffin/100g body weight, ip) for 7 days followed by 0.l ml of ccl4 (in liquid parafiin/100g body weight, ip) from day 8 till day 14, caused a 16 fold increase in lipid peroxidation and a 50% reduction in catalase and glutathione reductase in liver tissue of rats accompanied by an increase in the activities of transaminases. alkaline phosphatase, lactate dehydrogenase and gamma - glutamyl transpeptidase in serum as compared to liquid paraffin treated contro ...200515991578
antioxidant activity of phenolic and flavonoid compounds in some medicinal plants of india.in this study, total phenolics, flavonoids and vitamin c content vis-a-vis antioxidant activities were assayed in leaves and stem bark of azadirachta indica, butea monosperma, cassia fistula, mangifera indica, syzygium cumini and tamarindus indica using the 2,2-diphenyl-1-picrylhydrazyl (dpph) and superoxide radical scavenging method. the dpph radical scavenging activity positively correlated with the total phenolic content in both stem bark and leaf. superoxide radical scavenging activity incre ...201121726132
Antibacterial and antifungal activities from leaf extracts of Cassia fistula l.: An ethnomedicinal plant.This study was carried out with an objective to investigate the antibacterial and antifungal potentials of leaves of Cassia fistula Linn. The aim of the study is to assess the antimicrobial activity and to determine the zone of inhibition of extracts on some bacterial and fungal strains. In the present study, the microbial activity of hydroalcohol extracts of leaves of Cassia fistula Linn. (an ethnomedicinal plant) was evaluated for potential antimicrobial activity against medically important ba ...201122171301
isoprene emission from tropical tree species.foliar emission of isoprene was measured in nine commonly growing tree species of delhi, india. dynamic flow enclosure technique was used and gas samples were collected onto tenax-gc/carboseive cartridges, which were then attached to the sample injection system in the gas chromatograph (gc). eluting compounds were analysed using a flame ionisation detector (fid). out of the nine tree species, isoprene emission was found in six species (eucalyptus sp., ficus benghalensis, ficus religiosa, mangife ...200515701397
antioxidant activity of cassia fistula (linn.) flowers in alloxan induced diabetic rats.aqueous extract of cassia fistula (linn.) flowers (acf) was screened for its antioxidant effect in alloxan induced diabetic rats. an appreciable decrease in peroxidation products viz thiobarbituric acid reactive substances, conjugated dienes, hydroperoxides was observed in heart tissues of acf treated diabetic rats. the decreased activities of key antioxidant enzymes such as superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase and glutathione in diabetic rats were brough ...200415652272
the effect of medicinal plants of islamabad and murree region of pakistan on insulin secretion from ins-1 cells.in vitro testing of the extracts of medicinal plants collected from islamabad and the murree region on insulin secretagogue activity was carried out. dried ethanol extracts of all plants (zh1-zh19) were dissolved in ethanol and dmso, and tested at various concentrations (between 1 and 40 microg/ml) for insulin release from ins-1 cells in the presence of 5.5 mm glucose. glibenclamide was used as a control. promising insulin secretagogue activity in various plant extracts at 1, 10, 20 and 40 micro ...200414750205
screening for acetylcholinesterase inhibitory activity in plants used in thai traditional rejuvenating and neurotonic remedies.acetylcholinesterase (ache) inhibitor has been used as a drug for the symptomatic treatment of alzheimer's disease. in order to search for new ache inhibitors, 32 plants used in thai traditional rejuvenating and neurotonic remedies were collected. the plant methanolic extracts were tested for ache inhibitory activity using ellman's colorimetric method in 96-welled microplates. the results showed that the methanolic extracts from roots of stephania suberosa forman. and tabernaemontana divaricata ...200314611889
cassia fistula linn: potential candidate in the health management.cassia fistula linn is known as golden shower has therapeutics importance in health care since ancient times. research findings over the last two decade have confirmed the therapeutics consequence of c. fistula in the health management via modulation of biological activities due to the rich source of antioxidant. several findings based on the animal model have confirmed the pharmacologically safety and efficacy and have opened a new window for human health management. this review reveals additio ...026130932
antiradical and antilipoperoxidative effects of some plant extracts used by sri lankan traditional medical practitioners for cardioprotection.reactive oxygen species (ros) are implicated in many pathogenic processes including the cardiovascular system. detoxification of ros by antioxidants (ao) therefore affords protection against such diseases. there is a growing body of evidence suggesting that antioxidants contribute to cardioprotection. therefore, nine plants that are components of ayurvedic formulations used for the therapy of cardiovascular diseases were investigated to determine whether antioxidant activity is one of the mechan ...200111536382
hepatoprotective activity of cassia fistula leaf extract.hepatoprotective activity of the n-heptane extract of cassia fistula leaves was investigated by inducing hepatotoxicity with paracetamol in rats. the extract at a dose of 400 mg/kg body wt. exhibited orally, significant protective effect by lowering the serum levels of transaminases (sgot and sgpt), bilirubin and alkaline phosphatase (alp). the effects produced were comparable to that of a standard hepatoprotective agent.200111417916
antifertility effect of aqueous extract of seeds of cassia fistula in female rats.oral administration of aqueous extract of seeds of cassia fistula to mated female rats from day 1-5 of pregnancy at the doses of 100 and 200 mg/kg body weight resulted in 57.14% and 71.43% prevention of pregnancy, respectively, whereas 100% pregnancy inhibition was noted at 500 mg/kg bw. in the uterine bioassay test carried out in immature bilaterally ovariectomized female rats, aqueous extract of seeds of cassia fistula (100 mg/kg bw) increased the uterine wet weight (p<0.05) and luminal epithe ...199911145371
antibacterial activity of fistulin: a protease inhibitor purified from the leaves of cassia fistula.plant protease inhibitors (ppis) are one of the important components of a plant's defense machinery. ppis are active against the insects and microbes which invade the plant. cassia species possess anti-insecticidal and antimicrobial properties and this study was aimed at investigating the antibacterial efficacy of a ppi present in the leaves of cassia fistula. a ppi, fistulin, was isolated from the leaves of c. fistula and purified by gel filtration chromatography. the antibacterial activity of ...201222779011
evaluation of hepatoprotective activity of cassia fistula leaf extract.hepatoprotective activity of the n-heptane extract of cassia fistula leaves was investigated in rats by inducing hepatotoxicity with carbon tetrachloride:liquid paraffin (1:1). the extract has been shown to possess significant protective effect by lowering the serum levels of transminases (sgot and sgpt), bilirubin and alkaline phosphatase (alp). the extract of c. fistula at a dose of 400 mg/kg showed significant hepatoprotective activity which was comparable to that of a standard hepatoprotecti ...199910473173
antiplasmodial activity of the ethnobotanical plant cassia fistula.in our ongoing investigation of new compounds with activity against malaria parasites, we tested the in vitro antiplasmodial activity of fractions and purified compounds from cassia fistula l., a plant traditionally used by native populations of tanzania, zimbabwe, mozambique and brazil to treat malaria or symptoms associated with this disease. crude extracts from leaves, bark and fruits were tested for their antiplasmodial activity against the chloroquine-sensitive strain of plasmodium falcipar ...201223156984
the indian laburnum (cassia fistula l.) fruit: an analysis of its chemical constituents.the edible fruit tissue of indian laburnum fruit (cassia fistula l.), a member of the leguminosae family, was analyzed for certain organic compounds and mineral nutrients. of the nine macro- and micronutrients studied, k was the most highly concentrated such that 100% of the us recommended dietary allowances (rda) for adults could be met by the consumption of about 100 g of the fresh fruit. na contents in pulp and seeds are relatively low. ca content at 827 mg per 100 g of dry matter is one of t ...19957784398
antipyretic and analgesic activities of aconitum spicatum and cassia fistula. 19655885002
the biochemical role and hypocholesterolaemic potential of the legume cassia fistula in hypercholesterolaemic rats.the hypocholesterolaemic effect of cassia fistula was investigated using hypercholesterolaemic male albino rats. hypercholesterolaemia was induced by feeding on a mixture of cholesterol plus cholic acid for a 12 weeks period. hypercholesterolaemia was characterized by significant increase in the average levels of total lipids, total cholesterol, and triglycerides and significant decrease in phospholipids content. administration of cassia fistula significantly reduced blood and liver total lipids ...19911780005
minimum inhibitory concentrations of medicinal plants used in northern peru as antibacterial remedies.the plant species reported here are traditionally used in northern peru to treat bacterial infections, often addressed by the local healers as "inflammation". the aim of this study was to evaluate the minimum inhibitory concentration (mic) of their antibacterial properties against gram-positive and gram-negative bacteria.201020678568
antiulcer activity of ethanol leaf extract of cassia fistula.the ethanol leaf extract (ele) of cassia fistula linn. (caesalpinaceae) was evaluated for antiulcer activity against pylorus ligation-induced gastric ulcer. ranitidine (30 mg/kg b.w.) and ele at doses of 250, 500, and 750 mg/kg b.w. were administered orally in different groups of rats (n = 6), 1 h prior to pyloric ligation. four hours after pyloric ligation, the gastric juice was collected for evaluation of various parameters. the antiulcer activity of ele was evidenced by the significant attenu ...201020673173
traditional uses of medicinal plants reported by the indigenous communities and local herbal practitioners of bajaur agency, federally administrated tribal areas, pakistan.in the study area, knowledge related to the traditional uses of medicinal plants is totally in the custody of elder community members and local herbalists. the younger generation is unaware of the traditional knowledge, however with only few exceptions. therefore, this study was planned with objective to document the medicinal importance of plants, conserve this precious indigenous knowledge, and share it among other communities through published literature.201728108383
heavy metal bioaccumulation in selected medicinal plants collected from khetri copper mines and comparison with those collected from fertile soil in haridwar, india.heavy metal distribution in medicinal plants is gaining importance not only as an alternative medicine, but also for possible concern due to effects of metal toxicity. the present study has been focused on emphasizing the heavy metal status and bioaccumulation factors of v, mn, fe, co, cu, zn, se (essential metals) and cr, ni, cd, as and pb (potentially toxic metals) in medicinal plants grown under two different environmental conditions e.g., near to khetri copper mine and those in fertile soils ...201020390948
larvicidal and ovicidal activity of cassia fistula linn. leaf extract against filarial and malarial vector mosquitoes.methanolic leaf extract of cassia fistula was tested for larvicidal and ovicidal activity against culex quinquefasciatus and anopheles stephensi. the extract was found to be more lethal to the larvae of a. stephensi than c. quinquefasciatus with lc(50) values of 17.97 and 20.57 mg/l, respectively. mean percent hatchability of the ovicidal activity was observed 120 h after treatment. the percent hatchability was inversely proportional to the concentration of extract and directly proportional to t ...200817989995
insulin mimetic impact of catechin isolated from cassia fistula on the glucose oxidation and molecular mechanisms of glucose uptake on streptozotocin-induced diabetic wistar rats.diabetes mellitus is the most common and serious metabolic disorder among people all over the world. many plants have successfully been used to overcome this problem. cassia fistula, an ethnomedicnal plant, is widely used in indian medicine to treat diabetes. methanol extract of stem of plant, reduced the blood glucose levels in streptozotocin-induced diabetic rats. bioassay guided fractionation was followed to isolate catechin from methanol extract. catechin was administered to streptozotocin ( ...201019931438
evaluating the antifertility potential of an aqueous extract from cassia fistula seeds in male rats.cassia fistula suppresses fertility in male rats. withdrawal of extract restored all the altered parameters, including organ weights, fertility, circulatory level of hormones and tissue biochemistry, to control levels after 120 days.201019819443
ethno-medicinal application of plants in the eastern region of shimoga district, karnataka, india.the present paper aimed to document and study the role of traditional herbal drugs in the treatment of human and veterinary ailments by communities residing in the eastern part of shimoga district of karnataka in india and to determine the consensus of informant's knowledge on different category of ailments and fidelity level of plant species in treating particular disease.200919686831
protective effect of different parts of cassia fistula on human umbilical vein endothelial cells against glycated protein-induced toxicity in vitro.the protective effect of methanol extracts of cassia fistula (flowers, leaves and bark) was examined in vitro in human umbilical vein endothelial cells (huvec) against toxicity induced by glycated protein (gfbs) in vitro. the experiments consisted of eight groups of huvec with five flasks in each group. group i was treated with 15% fbs, group ii with gfbs (70 microm) alone, and the other six groups were treated with gfbs plus 25 and 50 microg of each of the three types of c. fistula extracts. af ...200819088944
protective effect of cassia fistula fruit extract against bromobenzene-induced liver injury in mice.in the present study, hepatoprotective effect of cassia fistula fruit extract was investigated in mice. animals were divided into six groups receiving normal saline (1), bromobenzene (460 mg/kg) alone (2) and together with increasing doses (200, 400, 600, 800 mg/kg) of a crude hydro-alcoholic extract of cassia fistula fruit (3-6, respectively). all administrations were carried out orally, daily, for 10 days. on the 11th day, animals were sacrificed. serum activities of aspartate aminotransferase ...201020930029
anti-advanced glycation end-product and free radical scavenging activity of plants from the yucatecan flora.formation and accumulation of advanced glycation end-products (age) is recognized as a major pathogenic process in diabetic complications, atherosclerosis and cardiovascular diseases. in addition, reactive oxygen species and free radicals have also been reported to participate in age formation and in cell damage. natural products with antioxidant and antiage activity have great therapeutic potential in the treatment of diabetes, hypertension and related complications. objective: to test ethanoli ...201727695268
study of the synergistic anti-inflammatory activity of solanum xanthocarpum schrad and wendl and cassia fistula linn.nonsteroidal and steroidal drugs are generally used as a part of drug therapy in inflammation. however, these drugs have severe side-effects like nausea and vomiting. therefore, there is a need to identify anti-inflammatory compounds that will be effective with a better safety profile. solanum xanthocarpum schrad and wendl and cassia fistula linn has many therapeutic uses mentioned in ayurveda and therefore we aimed to study its anti-inflammatory activity both alone and in combination.201021170209
phytoextraction capacity of the plants growing on tannery sludge dumping sites.the study was undertaken to assess the phytoremediation potential of four plants (sida acuta, ricinus communis, calotropis procera, cassia fistula) growing at a tannery sludge disposal site. results showed that maximum amount of k, fe and ni was associated with residual fraction, whereas, zn, mn, cr, pb, cd and co was found in fe-mn oxide fraction. cu and na were mostly associated with organic matter and carbonate fraction, respectively. the results demonstrated that the levels of accumulation o ...200716973356
protective effect of cassia fistula fruit extract on bromobenzene-induced nephrotoxicity in mice.the efficacy of a crude hydro-alcoholic extract of cassia fistula (golden shower tree) fruit to protect the kidney against bromobenzene-induced toxicity was studied. negative control mice received normal saline; positive control mice were given 460 mg/kg of bromobenzene; cassia fistula treated mice received 200, 400, 600 and 800 mg/kg of cassia fistula fruit extract followed by 460 mg/kg bromobenzene (daily by oral gavage for 10 days). on the 11th day, the mice were sacrificed, blood samples wer ...201121247991
aldose reductase inhibitory, anti-cataract and antioxidant potential of selected medicinal plants from the marathwada region, india.the water, ethanol and chloroform extracts of selected plants such as adhatoda vasica (l.) (acanthaceae), caesalpinia bonduc (l.), cassia fistula (l.) (caesalpiniaceae) and biophytum sensitivum (l.) (oxalidaceae) were evaluated for rat lens aldose reductase inhibitory (rlar) potential, anti-cataract and antioxidant activities. all the samples inhibited the aldose reductase considerably and exhibited anti-cataract activity, while c. fistula (ic(50), 0.154 mg ml(-1)) showed significant rlar inhibi ...201121462076
anticandidal activity of cassia fistula and its effect on ergosterol biosynthesis.context: cassia fistula linn. (caesalpiniaceae) has been used in folk medicine. anthraquinone derivative rhein having antimicrobial properties is actively present in c. fistula fruit. although, as yet there has been no study of its anticandidal potential. objective: the present study was conducted to determine the phytochemical composition of fruit pulp and seed extract and their effect on candida albicans atcc 10261, candida glabrata atcc 90030 and candida tropicalis atcc 750, respectively. mat ...201121591840
acute oral toxicity of methanolic seed extract of cassia fistula in mice.cassia fistula is widely used in traditional medicine to treat various types of ailments. the evaluation of toxic properties of c. fistula is crucial when considering public health protection because exposure to plant extracts can result in undesirable effects on consumers. hence, in this study the acute oral toxicity of c. fistula seeds extract was investigated in mice.201121701437
pruritus treatment in viewpoints of traditional persian medicine.pruritus is an unpleasant feeling that can cause the desire of scratching in a person and can be the symptoms of systemic, infectious, and neurological diseases. pruritus is the most common clinical manifestation of skin diseases. pruritus prevalence is 8-38% in the general population. causes and treatments of pruritus have been described by traditional persian medicine scientists. the aim of this study was to derive general principles of the proposed treatment to reduce or relieve pruritus.201627840519
comparison between the cassia fistula`s emulsion with polyethylene glycol (peg4000) in the pediatric functional constipation: a randomized clinical trial.there are few effective drugs for pediatric functional constipation (fc).201627660721
Antibacterial activities and phytochemical analysis of Cassia fistula (Linn.) leaf.Cassia fistula Linn. which belongs to family Leguminosae is a medium-sized tree and its different parts are used in ayurvedic medicine as well as home remedies for common ailments. Sequential extraction was carried out using solvents viz. petroleum ether, chloroform, ethanol, methanol and water from leaf of the plant were investigated for preliminary phytochemical and antibacterial property. Results of the study showed that all the extracts had good inhibitory activity against Gram-positive test ...201122171295
bioassay-directed isolation of active compounds with antiyeast activity from a cassia fistula seed extract.cassia fistula l belongs to the family leguminosae, and it is one of the most popular herbal products in tropical countries. c. fistula seeds have been used as a herbal medicine and have pharmacological activity which includes anti-bacterial, anti-fungal, and antioxidant properties. the goal of this study was to identify compounds from c. fistula seeds which are responsible for anti-candida albicans activity using bioassay-directed isolation.201121894090
structural analysis and biological toxicity of aflatoxins b1 and b2 degradation products following detoxification by ocimum basilicum and cassia fistula aqueous extracts.this study showed the comparison between ocimum basilicum and cassia fistula (leaves and branch) aqueous extracts for their ability to detoxify of aflatoxins b1 and b2 (afb1; 100 μg l(-1) and afb2; 50 μg l(-1)) by in vitro assays and decontamination studies. results indicated that o. basilicum leaves extract was found to be highly significant (p < 0.05) in degrading afb1 and afb2, i.e., 90.4 and 88.6%, respectively. however, o. basilicum branch, c. fistula leaves and branch extracts proved to be ...201627471501
ethnobotanical perspective of antimalarial plants: traditional knowledge based study.considering the demand of antimalarial plants it has become essential to find and locate them for their optimal extraction. the work aims to find plants with antimalarial activities which were used by the local people; to raise the value of traditional knowledge system (tks) prevalent in the study region; to compile characteristics of local plants used in malaria treatment (referred as antimalarial plants) and to have its spatial distribution analysis to establish a concept of geographical healt ...201626847459
in vitro antibacterial and antifungal activities of cassia fistula linn. fruit pulp extracts.aim of the study is to assess the antimicrobial activity cassia fistula fruit pulp extracts on some bacterial and fungal strains. hydro alcohol and chloroform extracts of cassia fistula fruit pulp were evaluated for the potential antimicrobial activity. the antimicrobial activity was determined in both the extracts using the agar disc diffusion method. extracts were effective on tested microorganisms. the antibacterial and antifungal activities of solvent extracts (5, 25, 50, 100, 250 μg/ml) of ...201223049197
spasmolytic effect of traditional herbal formulation on guinea pig ileum.the herbal formulation consisting of andrographis paniculata nees., cassia fistula l., foeniculum vulgare mill. and cuminum cyminum l. is widely used by the local traditional practitioners in rural northern karnataka for spasmodic abdominal pain.201726604555
evaluation of the effect of ethanolic extract of fruit pulp of cassia fistula linn. on forced swimming induced chronic fatigue syndrome in mice.the fruit of cassia fistula linn. is a legume, has antioxidant and lots of other medicinal properties. as oxidants are involved in the pathogenesis of chronic fatigue syndrome, the present study was done to evaluate the effect of ethanolic extract of fruit pulp of c. fistula linn. (eecf) on forced swimming induced chronic fatigue syndrome (cfs). albino mice of 25-40 grams were grouped into five groups (n=5). group a served as naive control and group b served as stress control. group c received e ...201726600847
the antibacterial activity of cassia fistula organic extracts.cassia fistula, is a flowering plant and a member of fabaceae family. its leaves are compound of 4 - 8 pairs of opposite leaflets. there are many cassia species around the world which are used in herbal medicine.201425147664
in vitro, in situ and in vivo studies on the anticandidal activity of cassia fistula seed extract.cassia fistula seeds have many therapeutic uses in traditional medicine practice. the present investigation was undertaken to demonstrate the anticandidal activity of the c. fistula seed extract at ultra-structural level through transmission electron microscope (tem) and scanning electron microscope (sem) observations. the effect of seed extract on the growth profile of the candida albicans was examined via time-kill assays and in vivo efficacy of the extract was tested in an animal model. in ad ...201222678414
fistulains a and b, new bischromones from the bark of cassia fistula, and their activities.fistulains a and b (1 and 2), two novel bischromones with unique coupling patterns, alone with their biosynthetic related compound 3, were isolated from the bark of cassia fistula. fistulain a represents a new type of dimeric chromone alkaloid biogenetically derived from a chromone and a tricyclic alkaloid through an unusual c-14-n linkage. fistulain b has a new carbon skeleton with a c-14-c-5' linkage formed between two different chromone units. fistulain a displayed anti-tmv activity, and both ...201525965347
isolation, characterization, and evaluation of cassia fistula linn. seed and pulp polymer for pharmaceutical application.present work, is an effort toward exploring the potential of cassia fistula linn. seed gum as an extended release polymer and laxative. while, c. fistula pulp polymer has evaluated as suspending agent.201425426443
biodiesel production from non-edible lignocellulosic biomass of cassia fistula l. fruit pulp using oleaginous yeast rhodosporidium kratochvilovae himpa1.this study explored biodiesel production from a low cost, abundant, non-edible lignocellulosic biomass from aqueous extract of cassia fistula l. (cae) fruit pulp. the cae was utilized as substrate for cultivating novel oleaginous yeast rhodosporidium kratochvilovae himpa1. this oleaginous yeast accumulates high amount of triacylglycerides as large intracellular lipid droplets (4.35±0.54μm) using cae as sole nutritional source. total lipids (4.86±0.54g/l) with lipid content of 53.18% (w/w) were p ...201526318927
ethnoveterinary plants for the treatment of camels in shiwalik regions of kathua district of jammu & kashmir, india.camel is an important mode of transportation in the hot and hilly tracts of shiwaliks of kathua districts. the camel owners of the region lack the modern veterinary facilities and therefore depend heavily upon local treatments for the animal. this ethnoveterinary knowledge of plants is acquired by them from their forefathers and generally moves from one generation to another orally. the oral mode of transferring this valuable knowledge is vulnerable to erosion with the passage of time and genera ...201525917839
response of three semi-arid plant species to fluoride; consequences for chlorophyll florescence.the study was done to investigate the ability of three semi-arid plant species viz. acacia tortilis, cassia fistula and prosopis juliflora to adapt to fluoride (f) stress. here we examined the changes in activities of chlorophyll a fluorescence and photosynthetic pigment concentration during early growth of these plants. one month old plants were treated with 10, 20, and 50 mg kg(-1) f in soilrite. we did not observe any major change in photosynthetic performance of these plants during early gro ...201424912239
anti-ulcer activity of leguminosae plants.ulcer is the most common gastrointestinal disturbance resulting from an inadequate gastric mucosal defense. several drugs are available in the market to address the disease; however, these drugs are associated with unnecessary side effects.201424760067
bioactivity of phytochemicals in some lesser-known plants and their effects and potential applications in livestock and aquaculture production systems.livestock and aquaculture production is under political and social pressure, especially in the european union (eu), to decrease pollution and environmental damage arising due to animal agriculture. the eu has banned the use of antibiotics and other chemicals, which have been shown to be effective in promoting growth and reducing environment pollutants because of the risk caused to humans by chemical residues in food and by antibiotic resistance being passed on to human pathogens. as a result of ...200722444893
screening and partial immunochemical characterization of sulfite oxidase from plant source.sulfite oxidase [so; ec 1.8.3.1] catalyses the physiologically vital oxidation of sulfite to sulfate, the terminal reaction in degradation of sulfur containing amino acids, cysteine and methionine. sulfite oxidase from vertebrate sources is among the best studied molybdenum enzymes. existence of so in plants has been established recently by identification of a cdna from arabidopsis thaliana encoding a functional so. the present study was undertaken to identify herbaceous and woody plants (viz., ...201020358871
effect of tamarindus indica linn. and cassia fistula linn. stem bark extracts on oxidative stress and diabetic conditions.tamarindus indica and cassia fistula are traditionally important medicinal plants. stem barks of these plants have not been much explored for their potential hypoglycemic and oxidative stress conditions. the main aim of present study was to evaluate antidiabetic activity along with renal complications and antioxidant potential of alcoholic extracts of stem barks of these plants. alcoholic extracts of stem barks of tamarindus indica and cassia fistula were evaluated for anti-hyperglycemic effect ...201624383324
ethnopharmacological assessment of medicinal plants used against livestock infections by the people living around indus river.the present study was aimed to document detailed ethnopharmacological knowledge of medicinal plants against livestock infections of an unexplored remote region of pakistan. semistructured questionnaires were used for data collection. total 43 plants belonging to 26 families were found to be used in ethnoveterinary practices. seeds (29%) were found to be the most frequent plant part used followed by leaves (22%). ethnoveterinary recipes were mostly prepared in the form of decoction and powdering. ...201425544941
chromatographic studies on a herb decoction.argwadhadhi kwatham is a compound preparation of 3 single drugs viz cassia fistula l. azadirachta indica a., tinospora cordifolia l. literature survey show tat all3 ingredients are very effective for skin diseases. kahayams prepared individually with these 3 drugs was found to be more effective for skin dideases. this paper deals with a comparative study of the chemical constituents present in aragwadhadhi kwatham and the individual kwathams, all the four kwarham were chemically analysed t.l.c. ...199822556839
efficacy of some botanical extracts against trogoderma granarium in wheat grains with toxicity evaluation.in an attempt to find alternative control methods for stored products insects, extracts of seven plant species (cassia senna, caesalpinia gilliesii, thespesia populnea var. acutiloba, chrysanthemum frutescens, euonymus japonicus, bauhinia purpurea, and cassia fistula) were evaluated under laboratory conditions for their ability to protect wheat (triticum spp.) grains against trogoderma granarium insect. moreover, gas chromatography-mass spectrometry (gc-ms) analysis was carried to identify the c ...201222606054
functionalized para-substituted benzenes as 1,8-cineole production modulators in an endophytic nodulisporium species.a nodulisporium species (designated ti-13) was isolated as an endophyte from cassia fistula. the fungus produces a spectrum of volatile organic compounds (vocs) that includes ethanol, acetaldehyde and 1,8-cineole as major components. initial observations of the fungal isolate suggested that reversible attenuation of the organism via removal from the host and successive transfers in pure culture resulted in a 50 % decrease in cineole production unrelated to an overall alteration in fungal growth. ...201424836622
[evaluation of traditional medicine: effects of cajanus cajan l. and of cassia fistula l. on carbohydrate metabolism in mice].the authors report the results of pharmacologic evaluation of two medicinal plants: cajanus cajan (l.) millsp and cassia fistula, which are used in panamanian folk medicine for the treatment of diabetes. it was found that the aqueous fraction of the leaves and stems of c. cajan did not produce any hypo blood sugar effect in normoglycemic mice; instead, it produced a hyperglycemia with doses of 500 mg/kg and 1000 mg/kg (p less than 0.001). only with a dose of 300 mg/kg a short lived decrease in t ...19912024054
bioactive amento flavone isolated from cassia fistula l. leaves exhibits therapeutic efficacy.novel natural compounds endowed with sound bioactivities are currently the utmost need as leads toward drug discovery. for the first time, here, we report the presence of amentoflavone (biflavonoid) in the leaves of cassia fistula l. structural characterization was carried out using ultraviolet-visible spectrophotometer, fourier transform infrared, nuclear magnetic resonance, and thin-layer chromatography. the isolated compound was further evaluated for its bioactivity. the compound demonstrated ...201728401469
cassia fistula: a remedy from traditional persian medicine for treatment of cutaneous lesions of pemphigus vulgaris.pemphigus is a rare autoimmune disease that may be fatal without proper medical intervention. it is a blistering disease that involves both the skin and mucus membranes, in which the most important causes of death comprise superimposed opportunistic infections and complications of long-term high-dose corticosteroid therapy or prolonged consumption of immune suppressant drugs. skin lesions are the most important sources of infection, and any local treatment decreasing the healing time of lesions ...201728348966
the effect of cassia fistula emulsion on pediatric functional constipation in comparison with mineral oil: a randomized, clinical trial. 201223351337
modulatory effects of cassia fistula fruits against free radicals and genotoxicity of mutagens.cassia fistula l. (fabaceae) fruits are highly recommended in folklore medicine for curing various ailments. in the current study, methanol (cafm), hexane (cafh), chloroform (cafcl), ethyl acetate (cafe), butanol (cafb) and aqueous (cafa) fractions of c. fistula fruits were investigated for their potential to inhibit the genotoxicity of mutagens and free radicals. the antimutagenicity of fractions was evaluated against the reactive carcinogenic ester generating mutagen, 2-aminofluorene (2-af) an ...201627984161
anti-aging and tyrosinase inhibition effects of cassia fistula flower butanolic extract.natural products made from plant sources have been used in a variety of cosmetic applications as a source of nutrition and as a whitening agent. the flowers of cassia fistula l, family fabaceae, have been used as a traditional medicine for skin diseases and wound healing and have been reported to possess anti-oxidant properties. the anti-aging effect of c. fistula flower extract on human skin fibroblast was investigated.201627912751
a review of flavonoids from cassia species and their biological activity.cassia is a large tropical genus with about 600 species that have been widely used as folk medicines in china and india. this genus has been known to possess various biological activities, e.g. antimicrobial, anti-inflammatory, antioxidant, anti-malarial, anti-mutagenic activity, and anti-fertility etc. flavonoids, for its broad spectrum of pharmacological activity and low toxicity, have attracted more interest in the development and utilization of natural medicines. the structure and biological ...201727538998
biochemical analysis of cassia fistula aqueous extract and phytochemically synthesized gold nanoparticles as hypoglycemic treatment for diabetes mellitus.cassia fistula stem bark was used for the preparation of aqueous extract and synthesis of gold nanoparticles to evaluate the hypoglycemic effects of the plant. the synthesized gold nanoparticles were characterized by ultraviolet-visible spectroscopy for their absorbance pattern, fourier transform infrared spectroscopy to identify possible functional groups, and scanning electron microscopy to determine the size of the nanoparticles. the present investigation reports the efficacy of the gold nano ...201222419867
observations on traditional usage of ethnomedicinal plants in humans and animals of kangra and chamba districts of himachal pradesh in north-western himalaya, india.medicinal plants are frequently used by gaddi and gujjar tribes of kangra and chamba districts of himachal pradesh, india to cure various ailments in humans and livestock. therefore, extensive field work was conducted to document the traditional use of ethnomedicinal plants by these tribes.201627321279
hypolipidemic and antioxidant effects of ethanol extract of cassia fistula fruit in hyperlipidemic mice.the plant cassia fistula l. (caesalpiniaceae) fruit was widely used by traditional practitioners to treat cardiovascular diseases (cvds) in india. hyperlipidemia is a lipid metabolism disorder and the major risk factor for the development of cvds. although most of the current hypolipidemic drugs are expensive and have potential side effects, the research focusing on natural alternative medicines is relevant.201627256804
evaluation of cytotoxicity and genotoxicity of some philippine medicinal plants.the genotoxicity and toxicity of ethnomedicinal philippine plants, which include cassia fistula, derris elliptica, ficus elastica, gliciridia sepium, michelia alba, morus alba, pogostemon cablin and ricinus communis, were tested using the vitotox assay. the plants are used traditionally to treat several disorders like diabetes, weakness, menorrhagia, headache, toothache and rheumatism. the dried leaves were homogenized for overnight soaking in methanol at room temperature. the resulting alcoholi ...201121716927
antifeedant and larvicidal activities of rhein isolated from the flowers of cassia fistula l.antifeedant and larvicidal activities of rhein (1,8-dihydroxyanthraquinone-3-carboxylic acid) isolated from the ethyl acetate extract of cassia fistula flower were studied against lepidopteron pests spodoptera litura and helicoverpa armigera. significant antifeedant activity was observed against h. armigera (76.13%) at 1000 ppm concentration. rhein exhibited larvicidal activity against h. armigera (67.5), s. litura (36.25%) and the lc50 values was 606.50 ppm for h. armigera and 1192.55 ppm for s ...201123961115
characterization of jamaican delonix regia and cassia fistula seed extracts.delonix regia and cassia fistula seed extracts were evaluated for their antioxidant activity, total phenolics, ash, zinc and fatty acid content. fourier transform infrared spectroscopy (ftir) was utilized to assess the chemical functionalities present within the seeds. antioxidant activity was determined by the 2,2-diphenyl-1-picrylhydrazyl (dpph) and trolox equivalent antioxidant capacity (teac) assays. total phenolics were determined by the folin-ciocalteu assay. lipid extracts were characteri ...201627034834
identification of a herbal powder by deoxyribonucleic acid barcoding and structural analyses.authentic identification of plants is essential for exploiting their medicinal properties as well as to stop the adulteration and malpractices with the trade of the same.201527013796
an investigation on cytotoxic effect of bioactive agnps synthesized using cassia fistula flower extract on breast cancer cell mcf-7.a single step protocol to produce biofunctionalized silver nanoparticles (agnps) using the aqueous extract of cassia fistula flower as "natural factory" was investigated. the reaction between silver ions and aqueous flower extract after the bioreduction process has resulted in the formation of reddish brown color colloidal solution. xrd pattern showed the face centered cubic crystalline structure of agnps and exhibited spherical morphology as characterized by fe-sem. ftir studies identified diff ...201528352579
laūq: a sustained-release dosage form for respiratory disorders in traditional persian medicine.laūq is a pharmaceutical dosage form that had been mainly used for the treatment of various respiratory disorders in traditional persian medicine. it is important from 2 aspects: a dosage form with efficient and optimum delivery of drugs to the respiratory tract and biological effects of its ingredients. natural medicine in laūq has been demonstrated to act in respiratory disorders by their antitussive, antiallergic, anti-inflammatory, antioxidant, spasmolytic, and antibacterial activities. some ...201626008751
biogenic synthesis of silver nanoparticles from cassia fistula (linn.): in vitro assessment of their antioxidant, antimicrobial and cytotoxic activities.the present study reports on biogenic-synthesised silver nanoparticles (agnps) derived by treating ag ions with an extract of cassia fistula leaf, a popular indian medicinal plant found in natural habitation. the progress of biogenic synthesis was monitored time to time using a ultraviolet-visible spectroscopy. the effect of phytochemicals present in c. fistula including flavonoids, tannins, phenolic compounds and alkaloids on the homogeneous growth of agnps was investigated by fourier-transform ...201627906147
three new anthraquinones from the twigs of cassia fistula and their bioactivities.three previously unreported anthraquinones, fistulaquinones a-c (1-3), together with three known ones (4-6) were isolated from the twigs of cassia fistula. their structures were determined by means of extensive nmr and ms spectroscopic analyses. all the isolated compounds were tested for their anti-tobacco mosaic virus (anti-tmv) activity, and compound 3 showed significant activity with inhibition rate of 34.5% at 20 μm concentration, even more potent than positive control. additionally, compoun ...201728152609
a new biologically active flavone glycoside from the seeds of cassia fistula (linn.).a new bioactive flavone glycoside 1 [mp 252-254 degrees c, c28h32o16, [m]+ 624 (eims)] was isolated from the acetone soluble fraction of the defatted seeds of cassia fistula (linn.). it was characterized as a new bioactive flavone glycoside 5,3',4'-tri-hydroxy-6-methoxy-7-o-alpha-l-rhamnopyranosyl-(1 --> 2)-o-beta-d-galactopyranoside by several colour reactions, spectral analysis and chemical degradations. compound 1 showed anti-microbial activity.200312608640
ethnomedicinal plants used for treating epilepsy by indigenous communities of sub-himalayan region of uttarakhand, india.although many plants are claimed to possess anticonvulsant/antiepileptic (ac/ae) properties, but there is very little information available about plants used by various ethnic communities in different parts of india to treat epilepsy, one of the most common disorders of central nervous system (cns); this communication provides significant ethnomedicinal information on the plants used by indigenous communities: bhoxa, tharu and nomadic gujjars of sub-himalayan region, uttarakhand, india to treat ...201324029249
large scale screening of ethnomedicinal plants for identification of potential antibacterial compounds.the global burden of bacterial infections is very high and has been exacerbated by increasing resistance to multiple antibiotics. antibiotic resistance leads to failed treatment of infections, which can ultimately lead to death. to overcome antibiotic resistance, it is necessary to identify new antibacterial agents. in this study, a total of 662 plant extracts (diverse parts) from 222 plant species (82 families, 177 genera) were screened for antibacterial activity using the agar cup plate method ...201626985889
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